KEGG   Rattus norvegicus (rat): 295037
Entry
295037            CDS       T01003                                 
Symbol
Mgst2
Name
(RefSeq) microsomal glutathione S-transferase 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    295037 (Mgst2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    295037 (Mgst2)
   00982 Drug metabolism - cytochrome P450
    295037 (Mgst2)
   00983 Drug metabolism - other enzymes
    295037 (Mgst2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    295037 (Mgst2)
   05204 Chemical carcinogenesis - DNA adducts
    295037 (Mgst2)
   05207 Chemical carcinogenesis - receptor activation
    295037 (Mgst2)
   05208 Chemical carcinogenesis - reactive oxygen species
    295037 (Mgst2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    295037 (Mgst2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    295037 (Mgst2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    295037 (Mgst2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    295037 (Mgst2)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     295037 (Mgst2)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   295037 (Mgst2)
SSDB
Motif
Pfam: MAPEG DUF6442 zf_UBZ
Other DBs
NCBI-GeneID: 295037
NCBI-ProteinID: NP_001099900
RGD: 1311218
Ensembl: ENSRNOG00000061857
UniProt: A6JV75 A0A8I5ZLK2
LinkDB
Position
2:137821787..137866664
AA seq 147 aa
MAGDSSLLAAVSLLSACQQSYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFY
SVFIISLWMAGWYFNQVFATCLGLLYIYARHKYFWGYAEAAEKRIIGFRLSLGILALLTV
LAVLGVASRFLDEYLDFHVAKKLKRPF
NT seq 444 nt   +upstreamnt  +downstreamnt
atggcgggggattcaagcctgctggctgcagtctcccttctctctgcctgtcagcaaagt
tattttgctttgcaagtcggacgagtaagattaaaatacaagatcgcacctccagcagtc
acgggctctctggagtttgagagaatatttcgcgcacagcaaaactctttggagttttat
tccgtattcatcatatcgctgtggatggctggatggtatttcaatcaagtttttgcaacc
tgtctgggtctcctgtacatatacgcccgtcacaagtatttctggggctatgcagaagcc
gctgaaaaaaggatcattggtttccggctgagcctgggcattttggccttgctgactgtc
ctcgctgtcctgggggtagcaagcagattcctggacgaatacctggactttcatgttgcc
aagaaactgaagcggcccttctaa

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