Rattus norvegicus (rat): 29516
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Entry
29516 CDS
T01003
Symbol
Pde3b
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
KO
K13296
cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:
3.1.4.17
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00230
Purine metabolism
rno01100
Metabolic pathways
rno04022
cGMP-PKG signaling pathway
rno04024
cAMP signaling pathway
rno04371
Apelin signaling pathway
rno04910
Insulin signaling pathway
rno04914
Progesterone-mediated oocyte maturation
rno04922
Glucagon signaling pathway
rno04923
Regulation of lipolysis in adipocytes
rno04924
Renin secretion
rno05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
29516 (Pde3b)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
29516 (Pde3b)
04024 cAMP signaling pathway
29516 (Pde3b)
04022 cGMP-PKG signaling pathway
29516 (Pde3b)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
29516 (Pde3b)
04922 Glucagon signaling pathway
29516 (Pde3b)
04923 Regulation of lipolysis in adipocytes
29516 (Pde3b)
04914 Progesterone-mediated oocyte maturation
29516 (Pde3b)
04924 Renin secretion
29516 (Pde3b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
29516 (Pde3b)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
29516 (Pde3b)
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Motif
Pfam:
PDEase_I
Sigma70_ner
CDC45
Motif
Other DBs
NCBI-GeneID:
29516
NCBI-ProteinID:
NP_058925
RGD:
61943
Ensembl:
ENSRNOG00000011417
UniProt:
Q63085
F1LQ35
LinkDB
All DBs
Position
1:178041207..178204503
Genome browser
AA seq
1111 aa
AA seq
DB search
MRKDERERDTPAMRSPPPPPPPATATAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCR
FCNVEPPAASLRAGARLSLAALAAFVLAALLGAGPERWAAAATGLRTLLSACSLSLSPLF
SIACAFFFLTCFLTRAQRGPDRGAGSWWLLALPACCYLGDFAAWQWWSWLRGEPAAAAAG
RLCLVLSCVGLLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAG
CLLALGLDHFFHVRGASPPPRSASTADEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRR
PSLPCISREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQV
ISSLRSISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSSKPSFPT
AQLRRSSGASGLLTSEHHSRWDRSGGKRPYQELSVSSHGCHLNGPFSSNLMTIPKQRSSS
VSLTHHAGLRRAGALPSPSLLNSSSHVPVSAGCLTNRSPVGFLDTSDFLTKPSVTLHRSL
GSVSSAADFHQYLRNSDSSLCSSCGHQILKYVSTCEPDGTDHHNEKSGEEDSTVFSKERL
NIVETQEEETVKEDCRELFLEGDDHLMEEAQQPNIDQEVLLDPMLVEDYDSLIEKMSNWN
FQIFELVEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHN
RVHATDVLHAVWYLTTRPIPGLQQLHNNHETETKADSDARLSSGQIAYLSSKSCCIPDKS
YGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASA
WNLYLSRPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFEFLAEFNAKANDVNSNGIE
WSSENDRLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEATLGLPISPFMD
RSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIEAEEGDDTESDDDDDDDDDDDDDD
DDDDEELDSDDEETEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEKCKAEG
NKLQVDNASLPQADEIQVIEEADEEEEQMFE
NT seq
3336 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaggacgagcgcgagcgggacacgccagccatgaggtccccgccgccgccgccg
ccgccggccacggccacggccgcctcgccccccgagagcctgcgcaacggctacgtgaag
agctgcgtgagcccgctgcggcaggaccctccgcgcagcttcttcttccacctctgccgc
ttctgcaacgtggagccgccggcggcctcgctccgcgccggggcacgcctctcgctcgcc
gctctggccgcctttgtcctggccgcgctgctgggcgcggggcccgagcgctgggcggcc
gcggcgaccgggcttcggacgctgctgagcgcttgctcgctcagcctcagcccgctcttc
agcatcgcctgtgccttcttcttcctcacctgcttcctgacgcgcgcgcagcgcggcccg
gaccgcggcgccggctcctggtggctgctggcgctgcctgcctgctgctacctgggcgac
ttcgcggcgtggcagtggtggtcgtggctgcgcggggagccggcggcggcggcggccggc
cggctctgcctggtgctgagctgcgtggggctgctgacgctcgcgcctcgcgtgaggctg
cggcacggagtcctggtgctgctcttcgccggcctggtgtggtgggtgtccttctccggc
ctcggggctctgccgcccgcgctcaggcctctgctgtcgtgcctggtcgggggcgcggga
tgcctgctagccctgggcttggaccacttctttcacgtccggggagcctcacctcccccg
cgctcggcgagtaccgcggatgaaaaagtgcctgtgatcagaccccggaggaggtccagc
tgcgtgtcgctgggagaaagcgcggccggttactatggcagtggcaagatgttcaggaga
ccgtcgttgccttgtatttctcgagaacagatgattctctgggactgggacttgaagcag
tggtgtaaacctcattaccagaattctggaggtggaaatggagttgatctttcagtgcta
aatgaagctcgcaatatggtgtcagaccttctgattgacccaagccttcccccacaagtc
atttcttctttgcggagtatcagtagcttgatgggtgctttctcaggttcctgtaggcca
aagattaattctttcacaccatttcctggattttatccctgttctgaagtagaagatcca
gtagagaaaggcgatcgaaaacttcacaaggggttgagtagcaaacccagtttcccgact
gcacagctgaggaggagctcaggagcgtcaggattgctgaccagtgagcaccactcacgg
tgggatcgcagcggtggcaaaaggccttaccaagaactcagtgtttcaagtcatggatgc
cacctaaatgggccttttagttcaaatcttatgacaattccaaagcagaggtcatcatct
gtgtcgctgacgcaccatgcaggtctgagaagagctggtgctttgcccagccccagtctt
ctgaattcttcaagccatgtacccgtgtctgctggctgtctaactaatcgatcacccgta
ggatttcttgataccagtgattttcttactaagccaagtgttactttacatagatcactg
ggcagtgtatccagtgcagcagatttccatcagtaccttaggaactctgacagcagtctg
tgtagcagctgtggacaccaaatactcaagtatgtttcgacatgtgaacctgatggtaca
gaccaccacaatgaaaaatcaggtgaagaagacagcactgttttctcaaaagaacgattg
aacattgtggaaactcaagaagaagagacagtgaaggaagactgcagggaattatttttg
gaaggtgatgatcacctaatggaagaggcccagcaaccgaatattgaccaggaagtgtta
ttggacccgatgttagtggaagattatgattcattaatagaaaagatgagcaactggaac
tttcagatttttgagcttgtagaaaaaatgggagaaaaatcaggaaggattctcagccag
gttatgtatactttatttcaagatactggtttattggaaacatttaaaattcccactcaa
gaatttatgaattattttcgtgcactagaaaatggctaccgagatattccatatcacaat
cgtgtgcatgccacagatgtcctacatgctgtttggtatttgacaacacgaccaattcct
ggcttacagcagctccataataaccatgaaacagaaaccaaagcagattcagatgctaga
cttagttctggacagattgcttacctttcttcgaagagttgctgtattccagataagagt
tatggctgcctgtcttcaaacattcctgcgttagaactgatggctttatatgtggcagct
gccatgcacgattatgatcacccaggaagaacaaatgcattcctagtggctacaaatgca
cctcaggcagttttatacaatgacagatctgttctagaaaatcatcatgccgcatcagcg
tggaatctgtatctttctcgcccagaatacaacttcctccttaaccttgatcacatggaa
ttcaagcgttttcgatttttagtcatagaagcaatccttgctacagatctcaaaaaacat
tttgagttccttgctgaattcaatgccaaggccaatgatgtaaatagtaacggtatagaa
tggagcagtgaaaacgatcgactcttagtctgccaggtgtgcatcaaattagcagacatc
aacggcccagcaaaagatcgggatcttcatttgagatggacagaaggcattgtgaatgag
ttttatgagcagggagatgaagaagcaaccctgggtctacctattagtcccttcatggat
cgttcttctcctcaactagcaaaactccaagagtcatttatcacccacattgtgggcccc
ctgtgcaactcctatgatgctgctggcttgctgcctggtcagtggatagaagcagaagag
ggtgacgatacagaaagtgatgatgatgatgatgatgatgatgatgatgatgatgatgat
gatgatgatgatgaagagttagattcagatgatgaagaaacagaagacaatctaaatcct
aaaccacaaagaaggaaaggcaggcggcgaatattttgccaactaatgcaccacctcact
gaaaaccacaagatctggaaggaaatcatagaagaggaagaaaaatgtaaagctgagggg
aacaaactgcaggtggataatgcctccttacctcaggcagatgagattcaggtcattgaa
gaagcagatgaagaggaagaacaaatgtttgaatga
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