Rattus norvegicus (rat): 29560
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Entry
29560 CDS
T01003
Symbol
Hif1a
Name
(RefSeq) hypoxia-inducible factor 1-alpha
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04066
HIF-1 signaling pathway
rno04137
Mitophagy - animal
rno04140
Autophagy - animal
rno04659
Th17 cell differentiation
rno04919
Thyroid hormone signaling pathway
rno05167
Kaposi sarcoma-associated herpesvirus infection
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05208
Chemical carcinogenesis - reactive oxygen species
rno05211
Renal cell carcinoma
rno05230
Central carbon metabolism in cancer
rno05231
Choline metabolism in cancer
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
29560 (Hif1a)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
29560 (Hif1a)
04137 Mitophagy - animal
29560 (Hif1a)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
29560 (Hif1a)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
29560 (Hif1a)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
29560 (Hif1a)
05205 Proteoglycans in cancer
29560 (Hif1a)
05208 Chemical carcinogenesis - reactive oxygen species
29560 (Hif1a)
05230 Central carbon metabolism in cancer
29560 (Hif1a)
05231 Choline metabolism in cancer
29560 (Hif1a)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
29560 (Hif1a)
09162 Cancer: specific types
05211 Renal cell carcinoma
29560 (Hif1a)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
29560 (Hif1a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
rno03000
]
29560 (Hif1a)
Transcription factors [BR:
rno03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
29560 (Hif1a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PAS_3
HIF-1a_CTAD
PAS_11
PAS
HIF-1
PAS_9
PAS_4
DDRGK
HLH
Motif
Other DBs
NCBI-GeneID:
29560
NCBI-ProteinID:
NP_077335
RGD:
61928
Ensembl:
ENSRNOG00000008292
UniProt:
O35800
LinkDB
All DBs
Position
6:92624059..92669262
Genome browser
AA seq
823 aa
AA seq
DB search
MEGAGGENEKKNRMSSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASV
MRLTISYLRVRKLLGAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKY
MGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVRKGKEQNTQRSFFLRMKCTLTSRG
RTMNIKSATWKVLHCTGHIHVYDTSSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDS
KTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQ
VTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTES
VLKPVESSDMKMTQLFTKVESEDTSCLFDKLKKEPDALTLLAPAAGDTIISLDFGSDDTE
TEDQQLEDVPLYNDVMFPSSNEKLNINLAMSPLPASETPKPLRSSADPALNQEVALKLES
SPESLGLSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNVFKLELVEKLF
AEDTEAKNPFSAQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESNSPSPPSVSTVTGFQ
QTQLQKPTITVTATATATTDESKAVTKDNIEDIKILIASPPSTQVPQEMTTAKASAYSGT
HSRTASPDRAGKRVIEKTDKAHPRSLNLSVTLNQRNTVPEEELNPKTIALQNAQRKRKME
HDGSLFQAAGIGTLLQQPGDRAPTMSLSWKRVKGYISSEQDGMEQKTIFLIPSDLACRLL
GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2472 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgagaacgagaagaaaaataggatgagttccgaacgtcgaaaa
gaaaagtctagggatgcagcacgatctcggcgaagcaaagagtctgaagttttttatgag
cttgctcatcagttgccacttccccacaacgtgagctcccatcttgataaagcttctgtt
atgaggctcaccatcagttacttacgtgtgaggaaacttctaggtgctggtgatcttgac
attgaagatgaaatgaaagcacagatgaactgcttttatctgaaagccctggatggcttt
gttatggtgctaacagatgatggtgacatgatttacatttctgataacgtgaacaaatac
atggggttgactcagtttgaactaactggacacagtgtgtttgattttacccatccatgt
gaccatgaggaaatgagagaaatgcttacacacagaaatggcccagtgagaaaggggaaa
gaacaaaacacgcagcgaagcttttttctcagaatgaaatgtaccctaacaagccggggg
aggacgatgaacatcaagtcagcaacgtggaaggtgctgcactgcacaggccacattcat
gtgtatgataccagcagtaaccagccgcagtgtggctacaagaaaccgcctatgacgtgc
ttggtgctgatttgtgaacccattcctcatccatcaaacattgaaattcctttagacagc
aagacatttctcagtcgacacagcctcgatatgaaattttcttactgtgatgaaaggatt
actgagttgatgggttatgagccagaagaacttttgggccgttcaatttatgaatattat
catgctttggactctgatcatctgaccaaaactcatcatgacatgtttactaaaggacaa
gtcaccacaggacagtacaggatgcttgcaaaaagaggtggatatgtctgggttgagact
caagcaactgttatatataatacgaagaactctcagccacagtgcattgtgtgtgtgaat
tatgttgtaagtggtattattcagcacgacttgattttctcccttcaacaaacagaatct
gtcctcaaaccagttgaatcttcagatatgaaaatgacccagctgttcactaaagtggaa
tctgaggacacgagctgcctcttcgacaagcttaagaaagagcccgatgccctgactctg
ctagctccagcggctggggacacgatcatatcactggacttcggcagcgatgacacggaa
actgaagaccaacaacttgaagatgtcccgttgtacaatgatgtaatgttcccctcttct
aatgagaaattaaatataaatctggcaatgtctccattacctgcctctgaaactccaaag
ccacttcgaagtagtgctgatcctgcactgaatcaagaggttgcattgaagttagagtca
agcccagagtcactgggactttcttttaccatgccccagattcaagatcagccagcaagt
ccttctgatggaagcactagacaaagctcacctgagcctaacagtcccagtgagtactgc
tttgatgtggacagcgatatggtcaatgtattcaagttggaactggtggaaaaactgttt
gctgaagacacagaagcgaagaatccattttcagctcaggacactgatttagacttggaa
atgctggctccctatatcccaatggatgatgatttccagttacgttcctttgatcagttg
tcaccattagagagcaattctccaagccctccgagtgtgagcacagttacaggattccag
cagacccagttacagaaacctaccatcactgtcactgccaccgcaactgccaccactgat
gaatcaaaagcagtgacgaaggacaatatagaagacattaaaatactgattgcatctcca
ccttctacccaagtacctcaagaaatgaccactgctaaggcatcagcatacagtggtact
cacagtcggacagcctcaccagacagagcaggaaagagagtcatagaaaaaacagacaaa
gctcatccaaggagccttaacctatctgtcactttgaatcaaagaaatactgttcctgaa
gaagaattaaacccaaagacaatagctttgcagaatgctcagaggaagcgaaaaatggaa
catgatggctccctttttcaagcagcaggaattggaacgttactgcagcaaccaggtgac
cgtgcccctactatgtcgctttcttggaaacgagtgaaaggatacatatctagtgaacag
gatggaatggagcagaagacaatttttttaataccctctgatttagcatgtagactgctg
gggcagtcaatggatgagagtggattaccacagctgaccagttacgattgtgaagttaat
gctcccatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat
caagttaactga
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