Rattus norvegicus (rat): 296091
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Entry
296091 CDS
T01003
Symbol
Pla2g4e
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00564
Glycerophospholipid metabolism
rno00565
Ether lipid metabolism
rno00590
Arachidonic acid metabolism
rno00591
Linoleic acid metabolism
rno00592
alpha-Linolenic acid metabolism
rno01100
Metabolic pathways
rno04010
MAPK signaling pathway
rno04014
Ras signaling pathway
rno04072
Phospholipase D signaling pathway
rno04217
Necroptosis
rno04270
Vascular smooth muscle contraction
rno04370
VEGF signaling pathway
rno04611
Platelet activation
rno04664
Fc epsilon RI signaling pathway
rno04666
Fc gamma R-mediated phagocytosis
rno04724
Glutamatergic synapse
rno04726
Serotonergic synapse
rno04730
Long-term depression
rno04750
Inflammatory mediator regulation of TRP channels
rno04912
GnRH signaling pathway
rno04913
Ovarian steroidogenesis
rno04921
Oxytocin signaling pathway
rno05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
296091 (Pla2g4e)
00565 Ether lipid metabolism
296091 (Pla2g4e)
00590 Arachidonic acid metabolism
296091 (Pla2g4e)
00591 Linoleic acid metabolism
296091 (Pla2g4e)
00592 alpha-Linolenic acid metabolism
296091 (Pla2g4e)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
296091 (Pla2g4e)
04072 Phospholipase D signaling pathway
296091 (Pla2g4e)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
296091 (Pla2g4e)
04664 Fc epsilon RI signaling pathway
296091 (Pla2g4e)
04666 Fc gamma R-mediated phagocytosis
296091 (Pla2g4e)
09152 Endocrine system
04913 Ovarian steroidogenesis
296091 (Pla2g4e)
04921 Oxytocin signaling pathway
296091 (Pla2g4e)
09156 Nervous system
04724 Glutamatergic synapse
296091 (Pla2g4e)
04726 Serotonergic synapse
296091 (Pla2g4e)
04730 Long-term depression
296091 (Pla2g4e)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
296091 (Pla2g4e)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
296091 (Pla2g4e)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
296091 (Pla2g4e)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
296091
NCBI-ProteinID:
XP_017447688
RGD:
1310595
Ensembl:
ENSRNOG00000024904
LinkDB
All DBs
Position
3:complement(127586318..127652369)
Genome browser
AA seq
900 aa
AA seq
DB search
MGQKSRLLSLRQEPRQETPSVDSGKPELESRHDASEADACLGFPLPVRHMPSRRWQVLGA
ERHGNERAAACLTLEMSTIGEETSQNKQCQKSMWAAARQEGSSPCHLLTVRIISMKNVRQ
ADILSQTDCFVTLWLPTASQKKLRTRTISNCPHPEWNESFTFQIQTRVKNVLEFSICDED
TLTQSDHLLTVLYDLSKLCLRNKTHVKFPLNPEGMEELEVEFLLEENVSSSETLITNGVL
VSRQVSCLEVHAESRRPRKRKKNKNLLVMVTDSFENTQCVQPCLEPCCPNPACFHYPKYS
QPQLYAEAPKSHWSYRLCCCEAQRNDTVCQPLDCLSDGQPMTLPLGENYELHMKSSPCSN
TLDVRLGFSLCQEEVEFLQKRKVAVTKALNQVLQLEEGLHEHEVPMIAIMATGGGTRSMV
SLYGHLLGLQKLNLLDCSVYLTGLSGATWTMATLYSDPEWSSKDLEPVVFEARRHVVKDK
MPALYPDQLCKWQEELRQHSQEGYKTTFTDFWGKLVEYSLGDKKNECKLSEQRAALCRGQ
NPLPIYLTINVKDDVSNQDFREWFEFSPYEVGMQKYGAFIPTELFGSEFFMGRLMKRIPE
PEMCYMLGLWSSIFSLNLLDAWNLSHTSEEFFYRWTREKLHDIEDDPLLPEIPRCDANPL
ETTVVIPATWLSNTFREILTHRPLVSEFHNFLYGLQLHTDYLQNKQFCMWKDTVLDTFPN
QLTQFTKHLNLLDTAFFVNSSYAPLLRPERKVDLIIHLNYCAGSQTKPLKQTCEYCTEQN
IPFPNYSIQEDDKSLKECYVMENPQEPDAPIVVYFPLINDTFQKYKAPGVERSPEELELG
QLNIYGPKSPYATKELTYTEAAFDKLVKLSEYNILNNKDKLIQAVRLAMEKKRMKSQCPS
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgggccagaaaagccggttgttgagcctcaggcaagagcccagacaggaaactcccagt
gtggattcaggcaagccagagctggagagccgccacgatgcttcagaggcagatgcctgc
ttgggtttcccactccctgtcagacacatgccaagcagaagatggcaggtgctcggagcg
gagagacacggaaatgaaagagcagcagcatgtctcactctagagatgtctacaatagga
gaggagactagccaaaacaaacaatgtcagaagagcatgtgggctgctgcacggcaggag
gggtcgtctccatgccatctattgacagtgaggatcattagcatgaaaaatgttcggcag
gctgatatattgagtcagacagattgctttgtgaccctctggctgcctactgcctctcag
aagaagctgaggaccagaaccatctccaactgcccacacccagagtggaatgaaagcttc
acctttcagatccagactcgagtaaagaatgttctagagttcagcatctgtgatgaagat
acgctgacacaaagtgaccatctcttgacagtcctctatgacctctccaagctctgcctt
cggaataaaacccacgtgaagttcccactcaacccagagggcatggaagaactggaagtg
gagttcctgctcgaagaaaatgtctcctcatcagagaccctcatcaccaatggcgtgctg
gtgtctcgccaagtctcttgcctggaagttcatgcagaatccaggaggccaaggaagagg
aagaaaaacaaaaaccttctggtgatggtgacagactccttcgagaacacccagtgtgtc
cagccctgtctggagccctgctgccccaatcctgcctgcttccactaccccaaatactcc
cagccccagctttatgcagaggcacctaagagccactggagctataggctttgctgctgt
gaagcacaaaggaatgacacagtctgccagcccctcgattgcctttctgatggccagccg
atgaccctgcctttgggagagaactatgagttacacatgaagtcctcaccctgctctaac
acactggatgtgcggctcgggttcagcctgtgccaggaagaggtggagtttctgcagaag
cggaaggtggcggtgaccaaggcactgaatcaagtgctgcaactggaggagggcctgcat
gagcatgaggtaccgatgatagccatcatggccacaggaggtggcacgaggtctatggtc
tccttgtatggccacttgctggggctgcagaagctgaaccttctggactgttctgtttac
ctcaccggcttgtcaggtgcaacctggacaatggctaccttgtacagtgatcctgagtgg
tcatccaaagacctggagcctgtagtctttgaggcccggagacatgttgtcaaagacaag
atgcctgcattgtacccagatcagctctgcaaatggcaagaggaactccgacaacacagc
caggagggctacaagaccacgttcacagacttttggggcaagctggtggagtacagtctg
ggagataagaaaaatgaatgcaagctgtcagaacagcgagctgctctgtgccggggacag
aaccctctgcccatctacctcactatcaatgtcaaggatgatgtaagcaaccaggatttc
agagaatggttcgagttctccccctacgaagtgggcatgcagaagtacggagccttcatc
cccacggagctatttggctctgagttcttcatggggcggctgatgaagaggattcctgag
ccagagatgtgctacatgctagggttgtggagtagcatcttttccctgaacctgcttgat
gcttggaatctgtcccacacctcggaggagtttttctataggtggaccagggagaaactg
catgacatcgaagatgatcccctcctgcctgaaatccccagatgtgatgctaaccccttg
gagaccacagtagtgatcccagccacatggctgtccaacaccttccgagaaatcctcaca
cacaggcccttggtgtctgagttccacaacttcctgtacgggttgcagctgcacaccgac
tacttacagaacaaacagttctgtatgtggaaagacacagtactggacactttcccaaac
cagctgacacagtttacaaaacacctgaacctgctggacactgcattctttgtcaactcc
agctatgcgcccctccttaggccagagagaaaagtcgaccttatcatccatctcaattac
tgcgcaggatcccagacaaagcccctgaaacaaacctgcgagtactgcacggagcagaat
atccccttccccaactactccatccaggaggacgacaaaagtctcaaggagtgctatgtg
atggagaatccccaggagcctgatgcgcccatcgtggtctacttcccactcatcaatgac
accttccagaagtacaaggctccaggtgtagagcgaagtcctgaggagctagaactgggc
cagctgaacatctatggaccaaagtctccctatgccaccaaggagctgacgtacacagag
gccgccttcgacaagctggtgaagctctcagagtataacatcctcaataacaaagacaag
ctcattcaggccgtgagactagcaatggagaagaaacgcatgaagagccagtgtccctcc
tag
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