Rattus norvegicus (rat): 299857
Help
Entry
299857 CDS
T01003
Symbol
Shmt2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform 1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00260
Glycine, serine and threonine metabolism
rno00630
Glyoxylate and dicarboxylate metabolism
rno00670
One carbon pool by folate
rno01100
Metabolic pathways
rno01200
Carbon metabolism
rno01230
Biosynthesis of amino acids
rno01240
Biosynthesis of cofactors
rno01523
Antifolate resistance
rno04981
Folate transport and metabolism
Module
rno_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
299857 (Shmt2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
299857 (Shmt2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
299857 (Shmt2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
299857 (Shmt2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
299857 (Shmt2)
Enzymes [BR:
rno01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
299857 (Shmt2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
299857
NCBI-ProteinID:
NP_001008323
RGD:
1308582
Ensembl:
ENSRNOG00000008106
UniProt:
Q5U3Z7
LinkDB
All DBs
Position
7:complement(65244247..65249580)
Genome browser
AA seq
504 aa
AA seq
DB search
MVPFSLLRTTRPLQRCGQLVCMAARAQHSEVAQKQAGEAAGGWTGQESLSDSDPEIWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKYADIVTTTTHKTLRGARSGLIFYRKGVRTVD
PKTGQEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLRNAQA
MADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKTAKLQDFKSFLLKDPETSQ
RLANLRQQVEQFARGFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atggtacccttctctttacttcggaccactcggcctctgcagagatgtggtcagctggtc
tgcatggctgcccgggcccagcacagtgaggtggcccagaagcaggctggggaagcagct
ggaggctggacgggccaggagagtttatcagacagtgaccctgagatatgggagcttctg
cagagggagaaggacagacagtgtcgtggcctggagctcatcgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctcaacaacaagtactcggagggttac
cctggcaagagatactacggaggagcagaagtcgtggacgagattgagctgctgtgtcag
cgccgggccttggaagcctttgacctggatcctgcacagtggggagtcaatgtgcagccg
tattcagggtccccagccaacctggctgcctacaccgcccttctgcagcctcatgatcga
atcatggggttggacctgcccgatgggggccacctcacccacggctacatgtctgatgtc
aagcggatctctgccacctccatcttcttcgagtccatgccgtataagctcaatccccaa
accggcctcatcgactacgaccagctagcgctgactgctcggcttttccgacctcggctc
atcatagctggcactagtgcctatgcccgcctcattgactatgcacgaatgagagaggtg
tgtgacgaagtcaaggcacacctgctggcagacatggcccatatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagtatgcggacatcgtcaccaccaccactcacaag
actcttcgaggggccaggtcaggactcatcttttaccggaagggagtgcggactgtagac
cccaagactggccaagagatcccttatacttttgaggacagaatcaacttcgctgtgttc
ccatccttacaagggggcccccacaatcacgccattgctgcagtagctgtggctctcaag
caggcctgcacccctatgttccgggagtactccttacaagtgttgcggaacgcccaagcc
atggccgacgccctgctcaagcgaggatactcgctggtgtctggtggcactgacacccac
ctggtgctggtggacctgcggcccaagggcctggatggagcacgggccgagcgtgtgttg
gagcttgtgtccatcacagccaacaagaacacctgtcctggagaccggagtgccattact
ccgggaggcttgaggcttggggccccagcattgacttctcgtcaattccgtgaggatgac
ttccggagggtcgttgattttatcgatgaaggagtcaacattggcttggaggtgaagcgc
aagactgccaaacttcaggatttcaagtccttcctgctcaaggacccagaaacaagtcag
cgtttggccaacctccggcaacaggtggaacagtttgccaggggcttcccaatgcctgga
tttgatgaacgttga
DBGET
integrated database retrieval system
