Rattus norvegicus (rat): 300944
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Entry
300944 CDS
T01003
Symbol
Xrn1
Name
(RefSeq) 5'-3' exoribonuclease 1
KO
K12618
5'-3' exoribonuclease 1 [EC:3.1.13.-]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno03008
Ribosome biogenesis in eukaryotes
rno03018
RNA degradation
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09120 Genetic Information Processing
09122 Translation
03008 Ribosome biogenesis in eukaryotes
300944 (Xrn1)
09123 Folding, sorting and degradation
03018 RNA degradation
300944 (Xrn1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
rno03019
]
300944 (Xrn1)
03009 Ribosome biogenesis [BR:
rno03009
]
300944 (Xrn1)
03016 Transfer RNA biogenesis [BR:
rno03016
]
300944 (Xrn1)
03036 Chromosome and associated proteins [BR:
rno03036
]
300944 (Xrn1)
Messenger RNA biogenesis [BR:
rno03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
300944 (Xrn1)
mRNA degradation factors
5'-3' decay
5' exonucleases
300944 (Xrn1)
Ribosome biogenesis [BR:
rno03009
]
Eukaryotic type
Pre-60S particles
RNases
300944 (Xrn1)
Transfer RNA biogenesis [BR:
rno03016
]
Eukaryotic type
tRNA degradation factors
Rapid tRNA decay (RTD) pathway factors
300944 (Xrn1)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Gene silencing
piRNA pathway
300944 (Xrn1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
XRN_N
XRN_M
XRN1_D2_D3
XRN1_D1
SH3_12
Dicer_dimer
Motif
Other DBs
NCBI-GeneID:
300944
NCBI-ProteinID:
NP_001292169
RGD:
1309713
Ensembl:
ENSRNOG00000042951
UniProt:
D4ABN8
LinkDB
All DBs
Position
8:105407785..105516967
Genome browser
AA seq
1719 aa
AA seq
DB search
MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI
FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE
TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK
IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA
PEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHL
HINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKW
FESKVGNKYLNEAAGAAAEEAKSCKDKRKVKGQENSLSWAALDKREGEGVASRDNFEDET
EDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLADQAACYVQAIQWILHYYYHGVQSWSWY
YPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPSASKTLLPTCYQHLMTSEDSP
IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM
CWYDSDTEFTYSSPWPEKFPAIERCSTRYKIISLDAWRVDINKNKITRVDQKALYFCGFP
TLKHIKHKFFLKKSGVQVFQQSSRGENMMLEITVNAEPDELSIENIASSVLGKSVFVNWP
HLEEARVVAVSDGETKFYMEEPPGTQKVYLGKTAPPCKVIQLSDKEQSNWTKEIQGISEQ
YLRRKGIMINETSAVVYAQLLTGRRYQVNQNGEVRLEKQWSKQSLPFVYQTIVKDVRAFD
SRFSNIKTLDDLFPPRSVVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDAL
IQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN
KKNEEVPGYTKRVGSEWMYSSAAEQLLAEYIERAPELFSYIAQNSQEDVFYEDDIWPGES
ESGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKNNKKVRVTV
KPHLLFRPLEQQHGAIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF
EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPAVSHCSV
NSSVSSGHMGGLNHSPQSLFLPTQVPTKGDDEFCNIWQSLQGSGKIQHLQPTVQEKGAVL
PQEISQVTESHKSGFNDHSVRHQQRKHDPHRKFKEEYKSPKAECQNQKLSNKQTSGASAR
CNIKLLKRNESPGTSEAQKVVTSYPNAVHKPHSGIESFLASLNISKESEVQLPHGEPPDE
AHLSPQSFAMKGTRMLKEILKIDSPDTTDSKNDVKKFDNEVMVSSSRRDEHGPSSHPKPT
SHVSQPHSTNEYQSVDSVCWPGHMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVC
QVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVNFPLPPPIFTNYPPAVPPGAVP
PVFPQPTANMMPSSSHLFGSVPWRPPVPVPGNAYHYPSYPATMPLAGGMPGGVHNQFIPL
QVTKKRVANKKNFENKEAQSSQATPLQTNKPGSSEATRMTPQEGSPASSASSQATQPVSS
HVETASQGHVVSHQRSAPSSSRRKSRKLAVNFSVSKPSE
NT seq
5160 nt
NT seq
+upstream
nt +downstream
nt
atgggagtccccaagttttaccgatggatctcggagcgatacccctgcctcagcgaagtg
gtgaaggagcatcagattcctgaatttgataacttgtacctggatatgaatggaattata
catcaatgttcccatcctaacgatgatgatgttcacttcagaatttcagatgacaaaatc
tttactgatatttttcactacttggaggtgttgtttcgaattattaaacctaggaaagtg
ttctttatggctgttgacggtgtggctcctcgagcaaaaatgaaccagcaacgtgggagg
cgttttaggtcagccaaggaggcagaagacaaaattaaaaaggcaatagaaaagggagaa
acacttcctacagaagccagattcgattccaactgtattacgccagggactgaattcatg
gccaggttgcatgaacatctgaagtattttgtaaatatgaaaatttccacagacaaatca
tggcaaggtgttaccatctacttctcaggccatgagactcctggagaaggagagcataaa
atcatggaatttatcagatccgagaaagcaaagccagatcatgatccaaacaccagacat
tgtctttatggcttagatgctgacttgatcatgcttggattaacaagtcacgaggcacat
ttttctctcttaagagaagaagttcggtttggtggaaaaaaaacacaaagggtatgtgca
ccagaagaaacgacgtttcacctcctacacttgtctttaatgagagagtatattgattat
gaattttcagcattaaaagaaaagatcacatttaaatatgatattgaaaaaattatagat
gattggattttgatgggatttcttgttggcaatgattttatccctcatctacctcattta
catattaatcatgatgcactgcctcttctttatggaacatatattgctatcctgccagaa
cttggaggttatattaatgaaagtggacatctcaacttacctcgatttgagagatacctt
gtgaagctgtcagactttgatcgagaacacttcagcgaagtttttgtggacctcaagtgg
tttgaaagcaaagttggtaacaagtatctcaatgaagcagcaggtgcggcagcagaagaa
gcaaagagctgcaaggacaagagaaaagtaaagggccaggaaaattctttaagttgggct
gcattagacaaaagagaaggtgaaggagtagcttctagagataattttgaagatgagact
gaagatgatgatctgtttgaaactgaatttagacaatataaaagaacatactacatgacg
aagatgggggtcgatgtagtatctgatgagtttctggctgatcaagctgcctgttatgtt
caggctatacagtggatcttacactattactatcatggagtccagtcctggagctggtat
tacccctatcattacgcacccttcctgtctgatatccgcaatatcagtacactcaagatt
cactttgaactgggcaagcccttcaagccgttcgagcagctcctcgctgtgcttccgtca
gccagtaagactttgcttcccacatgctaccagcatttgatgaccagcgaagactcgcca
attatagaatattatccacctgattttaaaactgatctaaatggaaaacaacaggaatgg
gaagccgtggtattaataccctttattgatgagaagcgattgttggaagccatggagaca
tgtaaccactccctcaagaaggaagaaaggaagagaaaccaacacagtgagtgcctaatg
tgctggtatgatagcgacacagagttcacctactcctctccatggccagaaaagttccct
gccatagaacgctgcagtacaaggtataaaataatatcattagatgcttggcgcgtagac
ataaacaagaacaaaataaccagggttgaccagaaggcattatatttctgtggattccct
actttgaaacacatcaaacataaattttttttgaagaaaagtggtgttcaagtattccag
cagagtagtcgtggtgaaaacatgatgttggaaatcacagtgaatgcagaaccagatgaa
ctcagtatagagaacatagcttcatctgtgctgggaaagtcagtctttgttaactggcct
catcttgaagaagctagagttgtggcagtatcggatggtgaaactaagttttatatggaa
gaacctccaggaacacagaaggtttatttgggaaaaactgctccaccatgtaaagtcatc
caactttcagataaagaacaatcgaactggactaaagaaatacaaggaatttcagaacaa
tatctaagaagaaagggaataatgataaatgaaacatctgctgttgtatatgctcagttg
ctcacaggtcgtagatatcaagtcaatcagaatggtgaagttcgtctagaaaaacagtgg
tcaaaacaaagtcttccttttgtttatcaaactattgttaaggatgtccgagcttttgac
tctcgtttctccaatatcaaaacactggatgatttgtttccccccagaagtgtggtgttt
atgcttgggactccttattacggctgcactggagaagttcaggactcgggtgatgtgata
acagaaggtaggattcgtgtggttttcagcattccatgtgaaccaaaccttgatgcttta
atacagaatcagcataaatactctataaagtacaacccaggatatgtgttggccggtcgc
cttggagtgagtggataccttgtttcaaggtttacaggaagtatttttattggaagagga
tctaggagaaaccctcatggagaccataaagcaaatgtgggtttaaatctcaaattcaac
aagaaaaatgaggaagtccctggctatacgaagagagtcgggagtgagtggatgtactcg
tcggcggccgagcagctacttgccgagtacatagagagagcaccagaactgtttagttac
atagcacagaacagccaagaggatgtgttctatgaggacgacatctggcctggagagagt
gagagcggggccgagaaagttcaagaaatcattacttggctgaaaggacatcctgtcagt
actctgtctcggtcttcctgtgacttacacattctggatgcagccattgttgaaaaaatc
gaggaagaagttgagaagtgcaagcaaagaaagaacaacaagaaagtccgagtgacagtg
aagcctcacttgctgttcagacctctagagcagcaacacggagccattcctgatcgggat
gctgagttccgcctctttgatcgcgttgtaaacgtgagagagaacttctcggtgccagtc
ggccttcgcggcaccatcattggaattaaaggggctaatagagaagctgatgtgctattt
gaagtattatttgatgaggaatttcctggaggcttaacaataaggtgctcacctggtcgg
ggataccgactgccaacaagtgccttagtgaacctttctcatgggagtcgctgtgaaact
ggaaaccagaagttgacagccattgtgaaaccacagccagctgtgagtcactgtagcgta
aactcatcagtttcctctgggcacatgggaggcctcaaccactctcctcagtcactcttt
cttcctactcaagtacctacaaaaggtgatgatgaattttgcaacatttggcaatctcta
cagggatctggaaaaattcaacacttgcagccaacggtacaagagaagggtgcagttcta
cctcaagaaataagtcaagtaactgaatctcataaatctggctttaacgaccatagtgtc
agacatcagcaaagaaaacatgaccctcaccgaaaatttaaggaagaatataagagtcct
aaagcggagtgtcagaatcaaaagttgtctaataaacagacttccggagcgtctgccaga
tgtaatattaaactattgaagagaaatgaaagtccaggaacttcagaagcccagaaggtt
gtaaccagttacccaaatgcagttcataagcctcactctggaattgagagctttttagca
tctttgaatatctctaaggaaagtgaagtacaattacctcatggagagcctccagatgag
gcacatctgtcaccgcagtcctttgctatgaaaggaacacggatgcttaaagaaattctg
aaaattgatagccctgacacaacagacagtaagaatgatgtgaaaaaatttgataatgaa
gtcatggtttcttctagtagaagagatgaacatggaccctcatcacatcctaagccaaca
agccatgtgagccagcctcacagtactaatgaataccagagtgtggacagtgtgtgctgg
ccaggccacatgcctcctgtgtccacaccagttactgaactctctcgaatttgttccctt
gttggaatgccacaaccggatttctcctttctgcggacaacacagacaatgacagtttgt
caggtgaagttgtctaatggcttgctggtgcatgggcctcagtgccactctgagagtgag
gccaaggaaagagccgcactgtttgctttacaacagctgggctccttgggtgtgaatttt
cctttgcctccaccaatatttacaaattatcctcctgcggtaccacctggagctgtcccg
cctgtctttccccaacctactgctaatatgatgccttcatcgtctcatctctttggctca
gtgccatggagaccaccagtgccagttcctgggaatgcctaccactatccttcatatcct
gcgaccatgcccttggctggaggaatgccaggtggagtgcacaatcagttcatacctctg
caggttacaaaaaaaagagttgcaaacaaaaagaattttgagaataaggaggcccagagt
tctcaagccacaccacttcagactaacaagccagggtcttctgaagccaccagaatgact
ccacaagaaggttcaccagcgtcttcagcgtcctctcaggctacccagcctgtgtcttct
cacgttgaaactgcatcccaaggccatgttgtgtcccaccagaggtcagctccaagctcc
tcaagaaggaaatcaagaaaattggctgtcaactttagtgtttctaaaccttctgaataa
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integrated database retrieval system
