KEGG   Rattus norvegicus (rat): 302470
Entry
302470            CDS       T01003                                 
Symbol
F8
Name
(RefSeq) coagulation factor VIII precursor
  KO
K03899  coagulation factor VIII
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04610  Complement and coagulation cascades
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    302470 (F8)
SSDB
Motif
Pfam: F5_F8_type_C Cu-oxidase_3 Cu-oxidase_2 F5_F8_type_C_2
Other DBs
NCBI-GeneID: 302470
NCBI-ProteinID: NP_899160
RGD: 727845
Ensembl: ENSRNOG00000031197
UniProt: D3ZEB1 Q7TN96
LinkDB
Position
18:155237..187186
AA seq 2258 aa
MRAARGLCFFLSLCALCSCATRKYYLGAVELPWDYVSGGASGAQRSDSRFPPGTPAPSAH
VVHTKTVFVEYMDRFFHTAKPRPLWMGLLGPTIWTEVHDTVVITLKNMASHPVSLHAVGM
SFWKASEGAAYDDHSSPAEKDDDKVLPGESHTYAWQVLGESGPMASDPPCLTYAYLSHVD
LVRDLNSGLVGALLVCKEGRLSADRTRMPPHFVLLFAVFDEGRSWHAATRDPASTEAQPT
VHTVNGYTNRTLPGLTGCRGTSVYWHVMAVGTTPDIHSILLEGHTFSVRSHRQASLEISP
MTLLTAQTWLMDLGRFLLFCHISSHRHGGMEAYVQVDNCPEAPQGQGKRDEDTEDYDDLD
SEMDVFTWDPDAAPFVQVRSAAKRHPKTWVHYIAAEEGDWDYAPAAATLEDGSLRNRYLG
RGPGRIGSKYKKVRFVAYTDGTFHTREATPREAGLLGPLLYGEVGDSLLIVFKNRASRAY
NIHPHGIRDVGAVHAGRLPRGVKHVKDLPIRPGETFKYRWTLTAEDGPARSDARCVTRYY
ASAVDPERDLASGLIGPLLICCKESVDQRGNQMMSDERNVILFSVFDENRSWYISENMRR
FLPDEAHVQLQDPEFEASNLMHSINGYVFDSLELRVCLHEVAAWHVLSVGAQTDFLSVFF
SGHTFRHRAVYADTLTVFPHSGVTVFMSMDNPGVWVLGCHNPDFRESGMTALLKVSSCDE
GVSDYYGETYEGVLAPLANDNAVDPRSFSQNSNHLHSRKKKSNTPMRFPLSHPTQHGSFW
SDSQGDVHDAVHRAHSPAAAHSNEGPAEAAQLEPKPHPGEKMALPPSWLRAKRSLVTTME
AKRKKLDLQVQVSGLPDDRTTAVVAPDDPMAACKKAGSSGFPDESSPAALGKKMYPRIRP
HGPLSIIEGNRDSNSSDSTLMYRLGSPPGDATSWTENRRGLGEKRSHRVAFLARGNTLLS
DVDEKSHAPGPTSVGNSTAAVQDTILEICSEILEVTPPIHDRILSDKSATYLRPHRTPDR
ITSTERKDIRHKKDGDLVPQDADDTSAPFSEAPFLSESTDWLKEANGDNSAKPEQEPSPE
QLVYLMYIKCMENQSFSSEKNKMIAGQGGFTKNTGLEDTVFPRKTSVFLTTVAKRQESGR
HNQENIPQAVTEKEAPIEEKGALPQVHIATGSKNFPRDMFVLGTGQNINLHEETYVPVHK
NVPWTRNPTDTRQIPMVHFFKKRKEEETNSGGLVNKTRETVRNYPSQKNSVARRREQASG
RIKASARWLPDVNRSIQSLLKQIDHRKERKKFIIESRSADSSGTKSPTQTNHSPSHVVKM
SAFPPRDIRRIESRDSSQVWVSSYAYDFETGSSRIRESSPFLNETETDNPSLAVPPRERF
VRRGRFASPEKVNTHSAPCDKPENVVSSEPVSPGEAVTVALPPHVSTQEEEPLPAGSSCE
RRGHVDLFLEISLQRTRGPVERSRGRRSGGDTEGHTENPGKTPSPLPQMPKDQRGSEAGY
PKICRWRDGTVLPPRPHNLSLGAKKKPNLPRREATRVEQGEAPSLVSPEPLVLRRRPREA
STLLPGGEMREDDGDGVTAEYDDDDDVMAEYDDDAVTVDTPEDFDIYGEEAGQGPRGFQQ
KTRHYFIAAVEELWDYGVRVSPGALGDRAWSGDAARFRKVVFREFTDGSFTQRVHRGELD
AHLGLLGPYIRAEVEDNIVVTFRNQASRPYSFYSSLVSYPEADGGAAPRSNFVRPNETKT
YFWRVRPHMAPTDGEFDCKAWAYFSDVDLERDLHSGLIGPLLVCHASTLHPSHARPLAVQ
EFALLFAVFDETKSWYCAENLDRKCRPPRGTPAGDPAWREEYRFHAVNGYVADALLGLVM
AEGRRTRWHLLSMGDPGHAQSVHFSAHSVTVRDGGEHRTAVCNLYPGVFTTVEMLPSRAG
IWRVESLVGEHLQAGMSALFLVYSTRCQVPLGMASGYIRDSQITASGYHGLWTPQLARLH
NAGSVNAWSAKEPFAWIKVDLLAPMILHGIETQGARHRLSSLYVSQFIIMYSLDGKQWLS
YRGNSTGSLMVFFGNVDASTVRHNRFDPPIVARYIRVHPTHASIRTALRMELLGCDLNSC
SAPLGMESGWISDTQVTASSHLSTTFSAWPPALARLHLRGGANAWRPQVNDPTQWLQVDL
QRTVKVTGVVTQGARSLLTAMFVKKFLVSTSQDGRHWTHVLQDGKVKVFQGNRDASTPMV
NSLHPPRFTRYLRIHPQVWERQIALRLEILGCEAQQLD
NT seq 6777 nt   +upstreamnt  +downstreamnt
atgcgcgcggcgcgcggcctgtgcttcttcctcagcctctgcgcgctctgctcctgcgcc
acccggaagtactacctgggcgccgtggagttgccatgggactatgtgagcggtggtgct
tccggtgcccagcgcagcgactccaggttccctcccgggacaccagcgccgtctgcgcat
gttgtgcacacgaagacggtgtttgtggagtacatggaccggtttttccacacggcaaag
cccaggccactgtggatgggtctcctaggccccaccatttggaccgaggttcacgacact
gtggtcatcacactcaaaaacatggcttctcatcccgtcagtctccacgctgtcggtatg
tccttctggaaggcgtccgagggcgcggcatacgacgaccacagcagcccggccgagaag
gacgacgacaaagtcctccccggcgagagccacacttacgcgtggcaggtcctgggggag
agcggcccaatggcttccgaccccccgtgcctcacctatgcctacctgtctcatgtggac
ctcgtgagggacctgaactcgggcctcgtcggggccctgctcgtgtgcaaagaaggccgt
ctgtccgcagacagaacacggatgccaccccacttcgtgctgctttttgctgtcttcgat
gaagggcggagctggcacgcagcaacacgtgaccccgcgtccaccgaggcccagcccacg
gtgcacactgtgaatggctacacgaaccggacactgccgggtctgaccggatgccgcgga
acatccgtgtactggcacgtgatggcggtgggcaccacgcccgacatacactccatcctc
ctcgaaggccacacattctctgtgaggagccaccgtcaggcttccctggagatctcacct
atgactctgctcacggctcagacgtggctgatggacctggggcggttcctgctcttctgt
cacatctcctcccacagacacggtggcatggaagcctacgtccaggtggacaactgcccc
gaggcgccccaggggcaggggaaaagggacgaggacacagaggactatgatgatctggac
tcggaaatggacgtcttcacctgggaccccgatgccgcccccttcgtccaggtccgctca
gcagccaagagacaccccaagacctgggtgcactacatcgcagcagaggagggggactgg
gactacgcgcctgcggccgccaccctagaagacgggagcctgcggaaccggtacctgggg
cgcggccctggccgcatcggcagcaaatataagaaagtcaggttcgtggcctacacggac
ggcacctttcacacgcgtgaggccaccccgcgtgaagctgggctcctagggccactgctc
tacggggaggtcggagactcactgttgattgtgttcaagaaccgagcgagccgggcatac
aacatccaccctcatgggatccgtgacgttggcgctgtgcatgcagggaggctgccacga
ggggtgaagcacgtgaaggatttgccgatccgcccaggagagacgttcaagtacaggtgg
acgctgaccgcagaggatgggcctgcaaggtcggatgcgcggtgtgtgacgcgctactat
gcgagcgctgtggatcccgagagagacctggcttccgggctgattggccccctcctcatc
tgctgtaaagaatctgtagatcaaagggggaaccagatgatgtcagacgagaggaacgtc
atcctgttctccgtgtttgatgagaaccggagctggtacatctcggagaacatgcgacgc
ttcctccccgacgaggcacatgtgcagctgcaggaccccgagttcgaggcctccaacctc
atgcacagcattaatggctacgtcttcgacagcctggagctgcgcgtttgcctgcacgag
gtggctgcctggcacgtgctcagcgtcggcgcgcagactgacttcctgtctgtcttcttc
tctggacacacgttcagacacagggcagtgtacgcagacacactcacggtgttcccgcac
tcgggggtcaccgtcttcatgtccatggataacccaggtgtgtgggtgctggggtgccac
aacccggacttccgggagagcgggatgaccgcactgctgaaggtttccagttgtgacgag
ggcgtgagtgattactacggagagacctatgagggcgttctggccccgttggccaatgac
aacgccgtggaccccaggagcttctcccagaattcaaatcatctgcacagcaggaaaaag
aaaagcaacacgccgatgcgcttcccactgagccatcctacccagcatggctccttttgg
tcggacagccagggagatgtccatgacgctgttcatagagcccattcacccgctgcagca
cacagcaatgaaggcccagccgaagcagcccagctcgagcccaaaccccatcccggtgag
aaaatggcacttcctccttcttggttaagagcaaagagaagtctggtgacaaccatggaa
gccaagcggaagaaactggatctccaggtccaggtttctggtttgcccgacgacagaaca
accgcagtggttgcgccggacgatccgatggcggcttgtaagaaggcgggttcttcaggg
tttccagatgaatcgagtcctgctgcattgggtaagaaaatgtatccccgtatcaggccc
cacggacctttaagcatcattgaaggaaacagggattccaactcgtcggactcgacttta
atgtataggctgggaagtccaccaggagacgccacatcatggacggagaaccgcagagga
cttggcgagaagaggtctcacagggtcgctttcctggccagaggtaacactttactcagc
gacgttgatgaaaaatcgcatgcccccggcccaacatcagttgggaacagcacagcagct
gtgcaggacaccatattagagatctgcagtgagattctcgaggtcacacctccgattcat
gacaggatactttcagacaaaagtgctacatatttgagaccgcaccgtacgcccgacaga
atcacctcgacggaaaggaaagacatacgtcacaaaaaagatggagatcttgttccgcag
gatgcagatgacacaagcgcaccattctcggaggcgcctttcctgtcagaatccacagat
tggttaaaagaggccaatggggataactccgcaaaacctgagcaagaacccagtccagag
caattagtgtatttaatgtatataaagtgtatggaaaatcagagtttctcgtcagagaag
aataaaatgatagcagggcaaggtggatttaccaagaacacaggacttgaagacacggtt
tttcccagaaagacgagtgtgtttctcaccactgtggctaagcggcaagaaagtgggagg
cacaaccaagaaaacattcctcaggcagtgacagagaaggaagcgccaatcgaagagaag
ggagctctgccccaggtgcacatagcgactggctctaagaacttcccgagagacatgttt
gtactcggtactgggcaaaatataaatctccacgaagagacatatgtaccagttcacaaa
aacgtcccatggacaagaaacccaacagacacaagacagattcccatggttcatttcttt
aagaaaaggaaggaggaggaaaccaattcaggaggcttggtaaataaaacgagagaaacg
gtgagaaactacccaagccagaagaatagcgttgctcgacgtagggaacaggcttcggga
cgaatcaaagcatccgctcgttggcttccagacgtaaaccgttcaatccagagtctcctt
aaacagattgaccaccgcaaggaaaggaaaaagttcattatagaatctcgctccgcagat
tcttctgggactaaaagtcccactcagaccaatcattctccctcacacgttgtgaaaatg
tcagcattcccaccgagagacatccgaaggatcgagtcgcgagacagttctcaggtctgg
gtgtcgtcctatgcttacgactttgagacaggaagttctagaattcgagagagcagtcct
ttcctgaatgaaactgaaacggataacccttctctcgccgtgccaccgcgggagaggttc
gtgcgtcgaggaaggttcgcctccccagaaaaagtgaacacacactcagcgccgtgtgac
aaacccgaaaatgttgtctcctcggaaccagtgtcgcctggcgaagctgtcacagtcgca
ctccctcctcacgtctccactcaggaggaggaacctttgcctgcaggaagtagctgtgag
cgtcgcggacatgtggatctctttctcgagatctctctccagagaacacgggggcccgtt
gaacggagtagaggaaggaggtctgggggagacacggaaggtcacacagagaaccccgga
aagactccctccccactgccacagatgccgaaagatcagcgtgggtctgaagcggggtac
ccgaaaatctgccgctggagagacggcactgttttgcccccgaggcctcacaacctttcc
ctaggagcaaagaaaaaaccaaatctgccccgaagagaagccactcgggtggagcaaggc
gaggctccgagcctggtctctccagagcccctggtgctgagacgacgtccaagggaagct
agcacccttctgccaggaggagagatgcgagaggacgacggtgatggtgtcacggcggag
tacgacgacgacgatgacgtcatggcagagtatgacgacgatgctgtcacggtggacacg
cccgaggatttcgacatctatggcgaggaggcagggcagggaccccgcggctttcagcag
aaaacgcggcactatttcatcgcggccgtggaggagctttgggactacggggtgcgtgtg
tcgcctggagctctgggagacagggcgtggagtggggacgcagctcggttccggaaagtg
gttttccgtgagttcacggacgggtcgttcacgcagcgtgtgcaccgtggggagctggac
gcacacctggggctattggggccatacatacgggcggaagtggaggacaacatcgtggtg
accttccggaaccaggcctcccgcccctactccttctactccagcctcgtgtcctacccg
gaagccgacggtggagctgcaccaaggagcaactttgtgcggcccaacgagaccaaaact
tacttctggagagtccggccccacatggcgcccacggacggcgagtttgactgcaaggcc
tgggcctatttctccgacgtggacctcgagcgagacctgcactcggggctgattgggcca
ctgctcgtgtgccacgcctccaccctgcacccctcgcacgcgcggccgctcgcagtgcag
gagttcgcgctgctcttcgcggtgttcgatgagaccaagagctggtactgcgctgagaac
ctggaccggaagtgcaggccgccccgtggcacccccgcgggagaccccgcctggagagaa
gagtaccgcttccatgccgtgaatggttacgtcgcagatgctctgcttggcctggtgatg
gcggaaggtcggaggacgaggtggcatctgctcagcatgggcgaccccgggcacgcacag
tccgtgcatttcagcgcgcacagcgtcaccgtgcgggacgggggcgagcacaggacggcg
gtgtgcaacctgtacccaggcgtgttcacaaccgtggagatgttgccgtccagagcgggg
atctggcgggtggagagcctggtgggcgagcacctacaggctgggatgagcgccctcttc
ctggtgtacagcacgcgctgccaggtcccgcttggcatggcttccggttacatccgggac
tcgcagatcacggcttccggctaccacgggctgtggaccccgcagctcgcgaggcttcac
aacgcgggatccgtgaatgcctggagtgccaaggagccattcgcgtggatcaaggtggat
ctcctggcgcccatgattcttcacggcatcgagacgcagggcgcccgacacagactttcc
agcctttatgtgtctcagttcatcatcatgtacagcctggatgggaagcagtggctgagc
taccgaggaaactccacgggaagcctgatggttttcttcggcaacgtggacgcgtccact
gtgaggcacaaccgcttcgaccccccgatcgttgcccgctacatccgtgtgcaccccaca
catgccagcatccgtaccgccctgcgcatggagctgctcggctgcgaccttaacagctgc
agcgcgcccctgggcatggagagtggatggatctcggacacgcaggtcactgcctcgtcc
cacctcagcaccacgttctctgcttggccgcctgcgctcgctcggcttcacctccggggt
ggggccaacgcctggcgaccccaggtgaatgatcccacacagtggctgcaggtggacttg
cagaggactgtgaaagtcaccggcgtcgtcacccagggtgcgcggtctctcctcactgcc
atgtttgtgaaaaagttcctcgtctccaccagccaagatggccgccactggactcacgtc
ttgcaagacggcaaggtcaaggtttttcagggtaaccgggatgcgtccacgcccatggtg
aactctctgcaccccccgcgcttcactcgataccttcggattcacccccaagtgtgggag
cggcaaattgctctgcggctcgagatcctggggtgtgaggctcagcagctggactga

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