Rattus norvegicus (rat): 309441
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Entry
309441 CDS
T01003
Symbol
Twnk
Name
(RefSeq) twinkle mtDNA helicase
KO
K17680
twinkle protein [EC:
5.6.2.3
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno05017
Spinocerebellar ataxia
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
309441 (Twnk)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
rno03029
]
309441 (Twnk)
Enzymes [BR:
rno01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
309441 (Twnk)
Mitochondrial biogenesis [BR:
rno03029
]
Mitochondrial DNA transcription, translation, and replication factors
Mitochondrial DNA replication factors
Mitochondrial DNA maintenance factors
309441 (Twnk)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_25
DnaB_C
ATPase
AAA_22
AAA_16
AAA_29
T2SSE
AAA_23
AAA_19
TsaE
ABC_tran
nSTAND3
SMP_C2CD2L
RsgA_GTPase
cobW
PhoH
Motif
Other DBs
NCBI-GeneID:
309441
NCBI-ProteinID:
NP_001101069
RGD:
1307884
Ensembl:
ENSRNOG00000014935
UniProt:
D3ZA68
A6JHH4
LinkDB
All DBs
Position
1:253817074..253823958
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AA seq
683 aa
AA seq
DB search
MWLLLRRAYPLRILLPLRGEWMGRRGLPRSLAPGPPRRRYRKEALPALEVPVSPVTTTEI
RQYLRAHGIPFQDGHSCLRAPSPFVAPSDIKNQKKDATTSFCLFIDKTTGHFLCMTSLAE
GSWEDLQASVEGRGDGAKEGILLGEGPEAEDREEVLRIWNRAIPLWELPDPQETQLARVM
FGLTKVTDDTLRRFNVRYLRSTRSLVFPWFTPGSSGLRGLKLLGVEGQENGVQYVETTIP
RPGVYHNLFGLPLIGRRDTEVVLTSRELDSLALSQSTGLPTLSLPRGTVCLPPALLPYLE
QFRRIVFWLGDDLRSWEAAKLFARKLNPKRCSLVRPGNQQPRPLEALNQGLSLPRILRTA
LPAWHKSIVSFRQLREEVLGELSNVDQAAGVRWSRFPDLNRLLKGHRKGELTVFTGPTGS
GKTTFISEYALDLCTQGVNTLWGSFEISNVRLARVMLTQFAVTRLEEQLDKYEEWADRFE
DLPLYFMTFHGQQSIRSVIDTMQHAVYVYDVCHVVIDNLQFMMGHEQLSTDRIAAQDYIV
GAFRKFATDNSCHVTLVIHPRKEDDDKELQTASIFGSAKASQEADNVLILQDRKLVTGPG
KRYLQVSKNRFDGDVGVFPLEFNKSSLTFSIPPKSKARLKKIKDDNGLVAKKSSSGKKGS
AHQNSETCIGQDPCQPDTSPSSR
NT seq
2052 nt
NT seq
+upstream
nt +downstream
nt
atgtggctccttctccggcgtgcttatcccctccggatcttgctgccactgcgtggggag
tggatgggtaggagaggcctgccccgaagcttggctccaggccctccccgaagaaggtac
agaaaagaagcgcttccagccttagaggtaccagtatcacctgtgactacaactgaaatc
cgccaatatttacgagcacatgggatccccttccaggatggccacagctgccttcgagca
ccaagtccctttgtggcaccctcagacatcaaaaatcagaagaaggatgctaccacttcc
ttctgcctcttcatcgacaagaccacaggacactttctctgcatgaccagcctagcagaa
gggagctgggaagacctccaggccagtgtggagggacgaggcgatggggccaaagaggga
atcctacttggggagggcccagaagctgaggacagggaggaggtcttgagaatctggaac
cgagccatacctctttgggagctgcctgatccccaggaaacccagctagctcgtgtgatg
tttggccttaccaaggtgacagatgacacactcaggagattcaatgtccgctatcttcga
tctactcgaagtctggtcttcccttggttcacccctgggagctcaggattacgtggcctg
aagctactaggggttgagggtcaggaaaatggagtacagtatgtagagaccaccattccc
cggcctggtgtctatcacaacctatttggattacccctgatcggccgtagagacactgag
gtggtcctgacaagtcgagagctggacagcctggccttgagccagtccacggggctgcca
accctttccctaccccgaggaacggtctgcttacccccagccctactcccttacctcgaa
cagttccggaggattgtgttctggctaggggatgaccttcgatcgtgggaagctgccaaa
ctgtttgcccgaaaactgaaccccaagcgatgctctttggtgaggcctgggaaccaacaa
cctcgtcccctggaggccttaaaccaaggcttaagtcttccccgtattctccgtactgcc
ctccctgcctggcacaagtctattgtgtcttttcgccagctccgagaagaggttttagga
gagctatcaaatgtggaccaagcagccggtgtccgttggagccgattcccagaccttaat
cggctgctgaagggtcatcggaagggcgagctgacggtctttacagggccaacaggcagt
ggcaagacaacattcatcagtgagtatgccctggacttgtgtacccagggagtgaacaca
ctgtggggtagctttgagatcagcaatgtgagactagcccgggtcatgctgactcagttt
gctgtgacacggctagaagaacaactggacaagtatgaagagtgggcagaccgttttgag
gacctgcctctctatttcatgactttccacggacaacagagcatcaggtctgtcatagac
acaatgcaacatgctgtctacgtctatgacgtttgtcatgtagtcatcgacaacttgcag
ttcatgatgggtcatgagcagctctctactgacaggatcgcagctcaagactacattgtt
ggagcctttcggaagtttgccacagacaatagctgccacgtgactctggttattcaccca
cggaaagaagatgacgacaaggaactacagacagcatccatttttggctcagccaaagcc
agccaagaagcagacaatgttctgatcttgcaggacaggaagctggtgactgggcctggg
aaacggtatctgcaggtgtccaaaaatcgctttgatggagacgtaggcgtcttcccactt
gagttcaacaagagttcccttaccttctccatcccacctaagagcaaagcccgactcaag
aagattaaggatgacaatggactagtggccaagaagtcctcctctggaaaaaaagggtct
gcgcaccagaactctgagacttgcataggccaggacccctgccagccagatacctccccg
tcctcaaggtga
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