Rattus norvegicus (rat): 310638
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Entry
310638 CDS
T01003
Symbol
Ash1l
Name
(RefSeq) histone-lysine N-methyltransferase ASH1L
KO
K06101
[histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:
2.1.1.354
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00310
Lysine degradation
rno01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
310638 (Ash1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rno03036
]
310638 (Ash1l)
Enzymes [BR:
rno01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
310638 (Ash1l)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
310638 (Ash1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SET
BAH
AWS
Bromodomain
PHD_5
PHD
PHD_2
Motif
Other DBs
NCBI-GeneID:
310638
NCBI-ProteinID:
NP_001101159
RGD:
1306350
Ensembl:
ENSRNOG00000020386
UniProt:
A0A0G2K2W6
A6J6B3
LinkDB
All DBs
Position
2:176644393..176780848
Genome browser
AA seq
2918 aa
AA seq
DB search
MDPRNTAMLGLGSDSEGFSRKSPSAISSGTLASKREVEIEGNTDEEDPRKRNRERAIEAG
KDDGLTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTVKHSRK
ALKSGKMTDEKNEHCPSKWDSSKLFKKAGDATAIECQSEESVHLHSQGENNPLSKKLSPV
HSQMADYIPAAPPLVGSRDPDIKDRALLNGGTSVTEKLAQLIATCPPSKSSKAKPKKLGT
GTTVGLVSKDLIRKPGVGSIAGIIHKDLIKKPALSTAVGLVTKDPGKKPMFNAAVSLINK
DSVKKLGTGTTAVFINKDLGKKPGTVTTVGLLSKDPGKKLGIGIVPGLVNKESGKKLGLG
TVVGLVNKELGKKLSSTVGLVAKDVTKKIVASSAMGLVNKDIGKKLLSCPIAGQLGSKDA
LNLKSEALLPTQEQLKASCSANISNHESQELPESLKDSATSKTFEKNVMRHSKESMLEKF
SVRKEITNLEKEMFNEGTCIQQDSFSSNERGAFETSKHEKQPPVYCTSPDFQIGGASDAS
TAKSPFGAVGESNLPSSSPTVSVNPLTRNPPETSSQLVPNPLLLNSTAEQMEEISESIGK
NQFTAESTHLNVGHRSLGHSISIECKGIDKELNESKSTHLDISRISSSLGKKPSLASDSG
IHTITPSVVNFTSLFSNKPFLKLGAVAAPDKHCQVAESLSTSFQSKPLKKRKGRKARWTK
VVARSTCRSPKGLDLERSELFKNVSCSSLSNSSEPAKFMKTIGASSFVDHDFLKRRLPKL
SKSSAPSLALLADSEKASHKSFITHKLSSSMCVTSDLLSDIYKPKRGRPKSKEMPQLEGP
PKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQSLSVSPFPKKRGRPKRQMRSPVK
MKPPVLSVAPFVATESPSKLESESENHRSSSDFFESEDQLQDTDDLEDSHRQSVCSVSDL
EMEPDKKISKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTV
SSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGLLSGSPASLAVLEQTAQQAAG
SALGQILPPLLPSPASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHVHSRQ
GSMIQTLAMKKAAKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPVSESHSDETIPSDSG
IGTDNNSTSDRAEKFCGQKKRRHSFEHISLIPPETSTVLNSLKEKHKHKCKRRSHDYLSY
DKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRI
NFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSY
GMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPTKYHKK
KHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSEQPQVSMD
TGSSRSVLESLKRYRFGKDTVGDRYKHKEKHRCHMSCPHLSPSKSLINREEQWVSREPSE
SSSLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHMNLFTSAIGSCRVSNPNSSC
RKKLTDSPGLFPVQDTALSRPHRKEPLPSTERAIQSLAGSQSASDKPSQRSSESTNCSPT
RKRSSSESTSSTVNGIPSRSPRLVASLDDSVDCLLQRIVQHDEQESVEKNGDAPITTVSA
PPSSSPGHSYSKERTLGKSDSLLVPAVPSDSCNSIPLLSEKLASRCSPHHIKRSVVEAMQ
RQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSM
QAFQAAQFVNPELNEGEEVSLHLSPDTVTDVIEAVVQSVNLNSEHKKGWKRKNWLLEEQT
RKKQKTVPEEEEQENNKSFIEKPVEIPSPLETPAEPSEPESNLQPVLALIPREKKAPRPP
KKKYQRAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVDVYVDVKPLSG
YEATTCNCKKPDDDTRKGCGDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERF
RAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVID
SYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDVPAGTELTYDYNFHSFNVEKQ
QLCKCGFEKCRGIIGGKSQRMNGLPSHKGSQPASTHRKSARSKEKRKSKHKLKKRRGHPS
EEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIHQKQEEVKHSRDIHST
SLYTRWNGICRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENLEVARAARLAQIFKE
ICDGIISYKDSSQQALAAPLLNLPPKKKNADYYEKISDPLDLSTIEKQILTGYYKTVEAF
DADMLKVFRNAEKYYGRKSPIGRDVCRLRKAYYSARHEASAQIDEIVGETASEADSSETS
VSEKENSHEKDDDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNTDVEHYLCEQCDPR
PVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLL
SHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIP
LEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAF
DHFPKKLTPKRDFSPHYVPDNYKRNGGRSSWKSERSKPLLKDLGQDDDALPLIEEVLASQ
EQAANEMPSPEEPDQERVTGDVSDAEKKPEESSQEPQLASTPEERRHSQRERLNQILLNL
LEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPENSFRK
NT seq
8757 nt
NT seq
+upstream
nt +downstream
nt
atggaccctaggaatactgctatgttaggattgggttctgactccgaagggttttcaaga
aagagtccttctgccatcagttctggcactctggccagcaagagagaagtagaaatagag
ggtaacacagacgaagaggatcctcgaaagcggaatcgagaaagggccatagaagcagga
aaagacgatggtttgacagatgcacagcaacagttttcagtgaaagaaacaaacttttca
gagggaaatttaaaattgaaaattggccttcaggctaagagaactaaaaagcctccaaag
aacttggagaactatgtgtgtcgccctgccataaaaacaactgtcaagcactcaaggaaa
gcacttaaaagtgggaagatgacagatgagaagaatgaacactgcccttcaaaatgggac
tcttcaaaattgttcaagaaagcaggtgatgctacagccatcgaatgccaatctgaagaa
agtgtccatcttcactctcagggggaaaataaccctttgtctaagaagctttctccagtg
cattcacaaatggccgattacattcctgcagcaccacctcttgttggcagtcgggatcct
gacataaaggacagagcattacttaatggaggaactagtgtaacagaaaagttggcacag
ctcattgctacctgtcctccttccaagtcttccaaggcaaaaccgaagaagttaggaact
ggcactacagtaggattggttagcaaggacttgatcaggaaaccaggtgttggttctata
gctggaataattcataaagacttaattaaaaagcctgctcttagcacagcagttggattg
gtaactaaagatccagggaaaaagcctatgttcaatgcagcagtaagcctgatcaataag
gactctgtgaaaaaattgggaactggcactacagcggtattcattaataaagacttaggc
aaaaagccagggactgtcactacagtaggactgctgagcaaagacccagggaagaagcta
ggaattggtatcgttccagggttagtgaataaagagtctggcaagaaattaggacttggc
accgtagttggactggttaataaagagttgggaaagaaattgagttctacagttggccta
gtggccaaggatgttacgaagaagattgtagcaagctcagcaatgggattggttaataag
gacattggaaagaaattattaagttgccccattgcaggacaactgggcagtaaagatgcc
ttaaaccttaaatctgaagcactgctccccactcaggaacaacttaaggcttcctgtagt
gcaaacataagtaatcatgaaagtcaagaacttcctgagtctctgaaagacagtgctacc
agcaaaacctttgagaagaatgttatgcggcatagtaaagaaagcatgttggaaaagttt
tcagtccgaaaagaaattactaatttggagaaagaaatgtttaatgaaggaacatgcatt
cagcaagacagtttctcatctaatgaaaggggagcctttgagacctcaaagcatgaaaag
caacctcctgtgtattgcacttctcctgactttcaaataggaggtgcctctgacgcatct
acagctaaatctccctttggtgcagtaggagaaagcaatcttccttcctcgtcacctact
gtatctgttaaccctttaaccagaaatccccctgaaacttcttcacagttggttccaaac
ccattacttttaaattctacagcagaacaaatggaagaaatttctgaatctattggaaag
aaccagttcactgctgaaagtacccacttgaatgttggtcataggtcattaggtcatagc
ataagtattgagtgtaaaggaattgataaagaactaaatgaatcaaaaagtacacatcta
gatatttctagaataagttcttccttgggaaaaaagccaagtttggcttctgactctggt
attcatacaattactccttccgttgttaattttactagtttatttagtaacaaacctttt
ctaaagcttggtgcagtagctgcaccagacaagcactgccaggtcgctgaaagcctaagc
actagtttccagtccaaaccattgaaaaaaagaaaagggagaaaagctcggtggactaaa
gtggtggcaagaagcacatgccgatccccaaaaggactagacttagaacggtcagagctt
tttaagaatgtttcctgtagctcactatcaaatagttctgagccagcaaagtttatgaaa
actatcggagcatcgtcttttgtcgatcatgacttccttaaacgccgattgccaaagttg
agtaagtcttcagctccatctcttgctcttttagccgacagtgagaaagcatctcataag
tcttttatcactcacaaactgtcctccagtatgtgtgtcactagtgatcttttgtcggat
atttataagcccaaaagaggaagacccaaatccaaggaaatgcctcaactagaaggtcca
cctaaaaggactttaaaaatacctgcctctaaagttttttctttacagtctaaagaagaa
caagaacccccaattttacaaccagaaattgaaattccttccttcaaacaaagtttgtct
gtatctccttttccaaaaaagagaggcaggcctaagaggcagatgaggtctccagtgaag
atgaagccccctgtactgtcagtggctccatttgttgccactgaaagtccaagtaagcta
gagtctgaaagtgagaaccatagaagtagcagtgatttctttgagagtgaggatcagctt
caggatacagatgacttagaggacagtcataggcaaagtgtctgcagtgtgagtgacctg
gagatggagccggataaaaaaattagcaagcgaaacaatggacaattaatgaaaacaatt
atccgcaaaataaataaaatgaagactttaaagagaaaaaaattgttgaatcagattctt
tcaagttctgtagaatcaagtaataaaggaaaagtacagtccaaacttcataatacagta
tcaagtcttgctgccacgtttggctctaaattggggcaacagataaatgtcagcaagaaa
ggaaccatttacatagggaagagaagggggcgaaaaccaaaaactgtcttaaatggcctt
ctttctggtagccctgccagccttgctgtgcttgaacaaacggctcagcaggcagctggg
tccgcattaggacagatcctccccccgttactgccttcacctgctagtagctctgagatc
cttccatcacctatttgctctcagtcttctgggactagtggaggtcagagccctgtcagt
agtgacgcaggctttgttgaacctagttcagtgccatatttgcatgtgcactcaagacag
ggcagtatgattcagactcttgcaatgaagaaggctgccaaaggcaggaggcggctatct
cctcctactttgttgccaaattctccttctcatttgagtgaactcacatccctgaaagaa
gccactccttccccagttagtgagtctcatagtgatgagaccattcccagtgacagtggc
attgggacagataataatagcacatcagacagggcagagaagttttgtggacagaaaaaa
aggagacattcttttgagcacatttctctgattccccctgaaacttctaccgtcctaaac
agtcttaaagagaaacacaaacacaaatgtaagcgcaggagtcacgattacctcagctat
gacaagatgaaaagacaaaagcgaaaacggaaaaagaaatatccccagcttcgaaatagg
caggatccagacttcatcgcagaactagaggagctgataagtcgtctaagtgagattcgg
attacccatcgaagtcatcatttcattccccgagacctcctgccaactatttttcgaatc
aactttaatagtttctatacacatccttcttttcccttagaccctttgcactacattcgg
aagcctgacttaaaaaagaaaagagggaggccccctaagatgagggaggcaatggcagaa
atgccctttatgcacagccttagttttcctttatctagtactggattttacccttcttat
ggcatgccttattctccttcacccctcactgctgctccgataggattagggtattatgga
cggtatccccccactctctatccaccacctccatctccttcattcaccactccactgcca
cctccctcctatatgcatgctggtcatttattgctcaatcctaccaaatatcataagaaa
aagcataagctccttagacaggaggcttttcttacaaccagcaggactcctctcctttcc
atgagcacctaccccagcgtacctcctgagatggcttatggttggatggtggagcacaaa
cacagacaccgtcacaaacacagagagcaccgttctgaacagccccaggtttccatggat
actggctcctccagatcggtcttggagtctttgaaacgttaccgatttggtaaggatact
gttggagatcgctataagcataaggaaaagcacaggtgtcacatgtcctgccctcatctc
tctccttcaaagagcttaataaacagagaagaacagtgggtttctcgagagccttcagaa
tcaagttctttagccttgggattgcaaacacctttacaaattgactgctcggaaagttct
ccaagtttgtcccttggaggatttactcccaattctgagccagccagcagtgatgaacat
atgaacctttttacaagtgcaataggcagctgcagagtttcaaaccctaactcgagctgc
cggaagaagttaactgacagccctggactctttcctgtacaagatactgcactaagtcgg
cctcacagaaaggaaccgttgccttccactgaaagggcaatacaatcgttggcaggttcc
cagtcagcttccgataaaccttcccagcgatcatcagaaagcacaaattgtagccctacc
cgtaaaaggtcttcatctgaaagtacttcttcaacagtgaatggaattccttccagaagt
cccagattggttgcttctctggatgactctgtagactgtctgttgcagcggatagttcaa
catgatgagcaagagtccgtggagaaaaatggtgatgctccaattacaactgtatctgca
ccaccttcttccagtccaggccatagctacagcaaagagcggaccctagggaaatcagac
agtcttctagtgcctgcagtcccgagtgactcttgtaatagtatcccacttctttctgaa
aagttagcaagcagatgttcccctcatcatatcaagagaagtgtagttgaagctatgcag
cgccaagctcggaaaatgtgcaattatgacaaaatcttggctaccaagaaaaatctggac
catgtcaataaaattttaaaagccaaaaaacttcaaaggcaggccaggacaggaaacaat
tttgtgaaacgcagaccaggtcgacctcggaaatgtcccctccaagctgtggtgtcaatg
caagcattccaggctgcccagtttgtcaacccagaattgaacgaaggcgaagaagtgtcg
ctgcacctaagtccagacacagttacggatgtgatcgaggctgtggttcagagtgtgaac
cttaattcagaacataagaaggggtggaagaggaaaaattggctgttagaagaacagact
agaaaaaagcagaagacagtaccagaggaagaagaacaagaaaacaataaaagctttata
gaaaaaccagttgaaattcccagtcctcttgaaaccccggctgaaccttctgaacctgaa
agtaacttacaacctgtgctggctctcatcccacgagaaaagaaagccccacgtcctcca
aagaagaaataccagagagctgggctgtattctgatgtctacaaaactacagacccaaag
agccgattaatccaactgaagaaagagaagttggagtacactccgggagagcatgagtat
ggactattcccagcacccattcatgttgatgtctacgttgatgtcaaacctctttctggt
tatgaggctaccacctgtaattgtaagaagccagatgatgacaccaggaagggctgtggg
gatgactgcctcaatagaatgatctttgctgagtgttcccctaacacgtgcccctgtggt
gagcagtgctgtaaccaaaggatacagagacatgagtgggtgcagtgtctggaacgattt
cgagctgaggaaaaaggttggggaattagaaccaaagagcccctaaaagctggccaattc
atcattgaatacctgggggaagttgtcagcgaacaagaattcaggaacaggatgattgaa
cagtatcataatcacagtgaccactactgtttaaacctggatagtggaatggtgattgac
agttaccgcatgggaaacgaggccagattcatcaaccacagctgtgacccaaattgtgaa
atgcagaaatggtctgttaacggagtgtaccgcattggattgtatgcacttaaggatgta
cccgctgggaccgagctcacctacgattacaactttcattccttcaatgtagaaaaacag
caactttgtaaatgtggttttgagaagtgtcgaggaatcattggaggcaaaagtcaacga
atgaatggactccctagccataaaggcagccagcctgcaagcacacatagaaagtctgca
cggtcgaaagaaaagcggaagtccaagcacaagctgaagaaaaggagaggccatccctct
gaagagcccagtgaaaacatcaacaccccaacaagattgactccacagttacagatgaag
ccaatgtccaatagagagaggaactttgtgttaaagcatcatgtgttcttggtccgaaac
tgggagaagatccatcagaagcaggaggaagtaaagcacagccgtgacatccactccaca
tccctgtacacccgatggaatggcatctgtagagacgatgggaacattaagtctgatgtc
ttcatgacccagttctctgccctgcagacagcgagatctgttcgcacaagacgcttggca
gctgcagaggagaacctggaagtggctcgggcagcacgcctggcccagatcttcaaagag
atctgcgatggcatcatctcctacaaagattcttcccaacaagctcttgcagctccactg
ttgaatcttcccccaaagaaaaaaaatgctgactattatgagaagatctctgacccgctg
gatctcagcaccatagagaagcagatcctcactggatactacaaaaccgtggaagctttt
gatgccgacatgcttaaggtctttcgaaatgctgagaagtattatgggcgtaaatccccg
attgggagagatgtttgccgcttaagaaaggcctattacagtgcccggcatgaagcttca
gctcaaatcgatgagattgtgggagaaacagccagtgaggcagacagcagtgagacctca
gtgtctgagaaggaaaacagccatgagaaggacgatgatgtgatccgctgcatctgcggc
ctctacaaggatgaaggcctcatgatccaatgtgacaagtgcatggtgtggcagcactgt
gactgcatgggtgtgaacacagacgtggagcactacctttgtgagcagtgtgacccccgg
cccgtggacagggaggtacccatgatccctagaccccactatgcccagcctgggtgtgtc
tactttatctgtttactccgagatgatttgctgcttcgtcagggtgattgtgtgtacctg
atgagggacagtcggcgcacacctgatggccacccagtccgtcagtcctatagactgtta
tctcacattaaccgagataaacttgacatctttagaatcgagaagctttggaagaatgaa
aaagaagaacggtttgcctttggtcaccattatttccgcccccatgaaactcaccactct
ccatcccgtcggttctatcacaatgagctatttcgggtgccactctatgagatcattccc
ttggaagctgtagttgggacctgctgtgtgttggacctttatacgtactgtaaagggaga
cccaaaggagtaaaggaacaagatgtatacatctgtgattatcggcttgacaagtcagca
caccttttttacaagatccatcggaatcgctatcctgtctgcaccaaaccctatgccttt
gatcatttccccaagaagctcactcccaaaagagacttctcacctcattatgtcccagat
aactacaagaggaacggaggacgatcgtcctggaagtctgaacgttcaaagccgctctta
aaagacctcggacaagatgatgatgctttgcccttgattgaagaggtgctggctagtcag
gagcaagcagccaatgaaatgcccagccctgaggagccagaccaggaaagagtcactggg
gacgtcagtgacgctgaaaagaagccagaggagagtagtcaagagccccagttagccagc
acgcctgaggagcgaaggcacagccagagggaacggctcaaccagatcctgctcaacctc
ctggagaaaatacctgggaaaaacgccattgatgtgacctacctgctggaggaagggtca
ggcaggaaactacgaaggcgcactttgtttataccagaaaacagctttcggaagtga
DBGET
integrated database retrieval system
