Rattus norvegicus (rat): 361100
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Entry
361100 CDS
T01003
Symbol
Top2b
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
361100 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
rno03032
]
361100 (Top2b)
03036 Chromosome and associated proteins [BR:
rno03036
]
361100 (Top2b)
Enzymes [BR:
rno01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
361100 (Top2b)
DNA replication proteins [BR:
rno03032
]
Eukaryotic type
DNA Topoisomerases
361100 (Top2b)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
361100 (Top2b)
Centrosome formation proteins
Centriole proteins
361100 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
361100
NCBI-ProteinID:
NP_001094328
RGD:
1586156
Ensembl:
ENSRNOG00000048795
UniProt:
Q14TE9
A0A8I5Y7L4
LinkDB
All DBs
Position
15:complement(11482089..11542464)
Genome browser
AA seq
1614 aa
AA seq
DB search
MAKSSLAGVDGALTWVNNAAKKEELETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYI
GSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP
ESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN
IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLAKFKMEKL
DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE
LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSV
KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI
LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS
GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL
RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS
IPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL
AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN
ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL
AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD
DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPN
YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP
ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK
YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK
DLIQMLVQRGYESDPVKAWKEAQEKAAEEEDAQNPHDDSSSDSGTPSGPDFNYILNMSLW
SLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS
GKAVKGKVGKAKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTTVVKV
EFDEEFSGTPAEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPASTGKPNTKKVKKR
NPWSDDESKSESDLEEAEPVVIPRDSLLRRAAAERPKYTFDFSEEEEDDADDDDDNNDLE
ELKVKASPITNDGEDEFVPSDGIDKDEYAFSPGKSKATPEKSSHDKKSQDFGNLFSFPSY
SQKSEDDSAKFDSNEEDTTSVFAPSFGLKQTDKVPSQTVAAKKGKAPSDAAAPKAKRAPR
QRKVVEPANSDSDSELGNIPKKTAAPKGKGRGAKKRKASGSENEGDYNPGRKPSKTASKK
PKKTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4845 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccagcctcgcgggcgttgacggggcgctgacctgggtgaacaatgctgca
aaaaaggaagagttggagacagcgaacaaaaatgattcttccaagaagttgtctgttgag
agagtgtaccagaagaagacccaactggagcatattctccttcgtcctgatacatacatt
ggatcagtggaaccactgacacagttaatgtgggtgtatgacgaagatgtaggcatgaac
tgcagagaggttacctttgttccgggcttatacaagatctttgatgaaattttggtcaat
gctgctgacaacaagcagagggataagaacatgacctgtattaaggtttctattgatcct
gaatctaatattataagcatttggaataatggaaaaggcattccagtagtagaacacaaa
gtagagaaagtttatgttcctgctttaatttttggacagcttttaacatcgagtaattat
gatgatgatgagaaaaaagttacaggaggccgtaatggttatggtgcaaaactttgtaat
atttttagtacaaagtttacagtagaaacggcttgcaaagaatacaaacatagttttaag
cagacatggatgaataatatgatgaagacttctgaagccaaaatcaaacattttgatggg
gaagattatacatgcataacattccagccagatctagccaagtttaagatggaaaaactt
gacaaggacattgtggccctcatgaccagaagggcatacgatttagctggttcctgcaaa
ggcgtcaaggtcatgttcaatggcaagaagttgcctgtaaatggatttcgcagctatgta
gacctttatgtgaaagacaaattggatgaaactggggtcgctctcaaagttattcatgaa
cttgcaaatgaaagatgggatgtttgtctaaccttgagtgaaaaaggtttccagcagatc
agctttgtgaatagtattgcaactacaaaaggtggacggcacgtggattacgtagtagat
caagttgttggtaaactgattgaagtagttaagaaaaagaacaaagctggtgtatcagtg
aagccatttcaagttaaaaaccacatatgggtttttattaattgtcttattgaaaatcca
acctttgattctcaaactaaggaaaacatgactctgcagcccaagagctttgggtctaaa
tgccagctgtcagaaaagttctttaaagcggcctctaattgtggcattgtagaaagcata
ttgaactgggtgaaatttaaggctcagactcagctgaataagaagtgctcctcagtaaag
tacagcaaaatcaaaggcattcccaaactggatgatgccaatgatgctggtggcaaacat
tccctggagtgtacattaatattaacagagggggactctgccaaatctctagctgtctct
ggattaggtgtgattgggagagacagatatggagtcttccctctcaggggtaaaattctc
aatgtacgagaagcgtctcataaacagattatggaaaatgcagaaataaacaatattatt
aaaatagttggtttgcaatacaagaaaagttatgatgatgcagaatctctgaaaacttta
cgttatgggaagattatgattatgactgatcaggatcaagatggttctcacattaaaggc
ctgctaatcaattttattcatcacaattggccatcacttttgaagcatggctttcttgaa
gaattcattactcccattgtaaaggcgagcaaaaataagcaggaactttccttttatagt
attcctgaatttgatgagtggaaaaaacatatagaaaaccagaaagcctggaaaataaag
tactacaaaggattgggtaccagtacagctaaggaagccaaggaatattttgctgatatg
gaaaggcatcgcattttgtttagatatgctggccctgaggatgatgctgccattaccttg
gcatttagtaagaagaagattgatgacagaaaagaatggttaaccaactttatggaggat
cggagacagcggaggttacatggcctaccagagcaatttttatatggtacagcaactaag
catttgacatacaatgatttcatcaacaaggaattgattctcttctcaaactcggacaat
gagagatctataccctctcttgtggatggcttcaagccaggtcaacgaaaagttttgttt
acctgtttcaagaggaatgataaacgtgaagttaaagtcgcacagctggctggatctgtt
gctgaaatgtctgcttatcatcatggagaacaagcgttgatgatgactattgtgaatttg
gctcagaattttgtgggcagcaacaacattaacttgcttcagcccattggtcagtttgga
actcggcttcacggtggcaaagatgctgcaagcccccgttatatcttcacaatgttaagc
tctctggcaagactactttttccagctgtggatgataacttgcttaagttcctttatgat
gataatcagcgtgtagagccggagtggtatatccccataatccccatggttttgattaat
ggtgctgagggtattgggactggatgggcttgtaaattgcccaactatgatgccagagaa
attgtgaacaatgtcaggcggatgctagaaggtttggatcctcaccccatgcttccaaac
tataagaacttcaaaggcaccatccaggagcttggtcagaaccagtatgctgttagtggt
gagatatttgtggtggacagaaacacagtagagattacagaacttccagttagaacctgg
acacaggtatacaaggagcaggtcctagaacctatgcttaatggaacagataaaacacca
gcactgatttctgattacaaagaatatcacactgatacaactgtgaaatttgtggtgaag
atgacagaagagaagctcgcccaagcggaagctgccggcctgcataaagtttttaaactc
caaaccactcttacttgcaattccatggtactctttgatcatatgggatgtctgaagaag
tatgaaactgtgcaagacattttgaaagaattctttgatttacggttaagttattatggt
ttacggaaggagtggcttgtaggaatgttgggagcagaatccacaaagcttaacaatcaa
gcccgtttcattttagagaagatacaagggaaaatcacgatagagaataggtcaaagaaa
gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgaaagcctggaaa
gaagcacaagaaaaggctgcggaagaggaagatgcacaaaacccacatgatgacagttcc
tctgactcaggaactccttcaggccctgattttaattatattttaaatatgtctctatgg
tctcttactaaagaaaaagttgaagaactcattaaacagagagatacaaaaggacgagag
gttaatgatctcaaaaggaaatctccctcagatctttggaaagaagatttagcagcattt
gttgaagaattggataaagtggaagcacaagaacgagaagacattctggcagggatgtct
gggaaagcagtgaaaggcaaagtcggcaaagctaaagtaaagaagctccagctggaggag
acgatgccctcgccttacgggagaagaatcgttcctgagattactgccatgaaggcagac
gccagcagaaaactgctgaagaagaagaagggtgatcctgatactacagttgtgaaagta
gaatttgatgaagaatttagtggaacaccagcagaaggtacaggagaagagacattgaca
ccatctgctcctgtaaataaaggccccaaacccaaaagggagaaaaaggagcctggtacc
agggttagaaaaacacctgcatcaactggcaaacctaatacaaagaaagtgaagaagcgg
aatccttggtcagatgatgagtccaaatcagagagtgacttggaagaagcagagcctgtg
gttatcccaagagattctttgcttaggagagcagctgctgaaagacctaagtacactttt
gatttctcagaagaggaggaggatgatgctgatgatgatgacgacaataatgatttagaa
gaattgaaagttaaagcatctcccataacaaatgatggggaggatgaatttgttccttca
gatggcatagataaagatgagtatgccttttctccaggcaaatccaaagctacaccagaa
aaatcttcacatgacaaaaaaagtcaggattttggaaatcttttttcatttccttcatat
tctcagaagtcagaagatgattcagctaaatttgacagtaatgaagaagacaccacatct
gtttttgcaccatcatttggtctgaagcaaacagataaagttccaagtcaaacagtcgct
gctaaaaagggtaaagcaccttcagatgcagcagcccctaaggccaagagagcccctaga
cagaggaaggtagtagagcctgcaaactccgactcggattctgaactcggcaacattcca
aagaagacggccgcaccgaaaggtaaaggccgaggggcaaagaaaaggaaagcatcaggc
tcagaaaatgaaggtgattataaccctggcaggaaaccatctaaaacagccagcaagaaa
ccgaagaaaacgtcttttgatcaggattcagatgtagacatcttcccttcagacttcact
tctgaaccacctgctctcccacggactggtcgggctaggaaagaagtaaaatattttgca
gagtctgatgaagaagaagacgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
