Rattus norvegicus (rat): 367072
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Entry
367072 CDS
T01003
Symbol
Arhgef12
Name
(RefSeq) rho guanine nucleotide exchange factor 12
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04270
Vascular smooth muscle contraction
rno04360
Axon guidance
rno04611
Platelet activation
rno04625
C-type lectin receptor signaling pathway
rno04810
Regulation of actin cytoskeleton
rno05135
Yersinia infection
rno05152
Tuberculosis
rno05163
Human cytomegalovirus infection
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
367072 (Arhgef12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
367072 (Arhgef12)
04625 C-type lectin receptor signaling pathway
367072 (Arhgef12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
367072 (Arhgef12)
09158 Development and regeneration
04360 Axon guidance
367072 (Arhgef12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
367072 (Arhgef12)
05205 Proteoglycans in cancer
367072 (Arhgef12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
367072 (Arhgef12)
09171 Infectious disease: bacterial
05135 Yersinia infection
367072 (Arhgef12)
05152 Tuberculosis
367072 (Arhgef12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
367072 (Arhgef12)
Membrane trafficking [BR:
rno04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
367072 (Arhgef12)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
Ribonuc_2-5A
AAA_23
Motif
Other DBs
NCBI-GeneID:
367072
NCBI-ProteinID:
NP_001013264
RGD:
1305111
Ensembl:
ENSRNOG00000008924
UniProt:
Q5BMA6
LinkDB
All DBs
Position
8:complement(52247047..52373158)
Genome browser
AA seq
1545 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSTSHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLAESEVEPSVIGHMSPIMTSPHSPG
AAGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTATQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVIAPSRPLGDALTLSEAETDPGDGLCRTDWSSGDAS
RPSSDSADSPKSSLKERVCLEDTPERTEGVQDADTQSLVGSPSTRGAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLRVSVPEEISVDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRGTLEKERACAEQIVTKIEEVLMTAQAVEEER
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMEIQKLRHPKHLSAPSSMSPELQDPAKLRQSGVANEGTDTGY
LPASSMSSATSGAALSQEGGRENDTGAKQVGDAVAPGDCLDSIPRVPNTVFDFPPPLLDQ
VQEEECEVERVAEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHVGLNEQMKAVRKRNETSVIDHIGEDLLLWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPPEREKV
KKAADQCRQILNYVNQAVREAENKQRLEDYQRRLDTSSLKLSEYPNVDELRNLDLTKRKM
IHEGPLVWKVNRDKSIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPQPPPCEGDNDEEEPAKLKVEHHDLSVAGLQSPDRVLGLESPLISSKPQSHSMNTP
GKSEAEHLFVTATQFAKEQHANGTFKEGDGGYPVTISDPHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKTTQEDWRSFSRYRPASEEAQADSGIPDLESVKACHAGEGQMSFKTGTG
DVATCDSPRTSTESCAVQDSVILASQDSQASNIIEMDHMLLTPEVPTTAEPEGGLDDSGE
HFFDAREAHSDDNPSEGDGAVRKEEEDVNVRISGNCLILDGYDAVQESSTDEEIASSFTL
QPVTGLPSVDSSHQQQHSPQNAISEGAISPSTPEFLVQRRWRAVEDACSEVQSPSAWTDS
QSQILEYIHKIEADLEHLKKVEESYTLLCQRLAGSALPDKVSDKS
NT seq
4638 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctactatcacggacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaaccgagagtcaccaacagataagaaacagaaagtcgaacgcagcaca
tcacatgattttgaccccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatctatggtcttgttcagcgctgtgtgatcatccagaaagatgacaat
ggattcgggctgacagtcagcggggacaatccagtcttcgtacaatctgtcaaagaagat
ggagcagccatgcgcgctggagtacaaacaggtgatcgaatcatcaaggtgaatgggact
ctggtgactcattcaaatcatctggaggtggtgaaactaatcagatctggttcctatgta
gctctcactgtccagggacgcccacctgggtcgccccagattccacttgctgagtctgaa
gtagaaccatcagtcattggacatatgtctcccattatgacatcccctcattcccctgga
gcagccgggaacatggagagaatcactagtcctgtgctcatgggggaggaaaacaatgtg
gtccataaccagaaagtagagattctgaggaaaatgttacagaaagaacaggagcgtctg
cagttactgcaggaagattacaaccgaacggctacccagagattgctcaaggagatccag
gaggccaagaagcacatcccccagctgcaggagcagctgtccaaagccacaggctctgct
caggacggagctgtaattgcaccctccaggccattaggtgatgccctaacactcagcgag
gcagaaacggaccctggagacggcctgtgcaggactgactggagcagtggagatgcttct
cggcccagtagtgacagtgcagatagccccaagagtagcctgaaggaaagggtttgtctc
gaggacaccccagagaggactgaaggagttcaggatgctgacacacagtcgctggtcggc
agtccctccacccgtggcgcccctcatattatcggagcagaggatgatgattttggtact
gaacacgagcagatcaatggacagtgcagctgtttccagagcattgagttgctgaagtct
cgccctgcccacttggctgttttcttacaccatgtagtctcacagtttgaccctgcaaca
ttgctctgttatctctattcagacctgtataagcagacgaactccaaggagactcggcgg
gtcttcctggagtttcatcagttcttcttggaccgatctgcacacctgagagtttccgtc
cccgaggaaatctctgtggatctagaaaagagaagacccgagctcattcctgaggatctg
catcgccattacattcaaacaatgcaggagagggttcaccctgaagttcagaggcacttg
gaggattttcgacagaaacgcagcatgggactgaccttggctgagagtgagctgaccaaa
cttgatgcagagagagacaaggaccggggaactctggagaaggagcgagcatgtgcggaa
cagatcgttaccaaaattgaagaagtattgatgactgctcaggctgtagaagaagaaagg
agttccaccatgcagtatgtaattctcatgtatatgaagcatttgggagtaaaagtgaaa
gaacctcgaaacttggagcacaagcggggtcggatcggcttccttccgaagatcaagcaa
agcatgaagaaagatagagagggggaagaaaaagggaagcgaagaggattccccagcatt
ttgggacccccaagaagaccaagccgccatgacaacagtgcaattggcagggccatggag
atacagaagcttcgccacccgaagcacttgtccgcaccctcatctatgagtcctgagctt
caggaccctgctaagttgcgccagagtggagtagccaatgaaggaacagacactggatat
ctgcctgccagttccatgtcctctgccacctcaggggctgctctttcccaagagggaggg
agagagaatgacacaggagcaaaacaagttggagacgcggtggcacctggagactgcttg
gatagcatacctcgagtccccaatactgtttttgacttccccccgcctctgctagatcaa
gtgcaggaggaggaatgtgaagtggagagggtggcagaacatggaaccccaaaacccttt
cgaaagtttgacagcatcgcctttggagaaagtcagagtgaggacgagcagtttgaaaat
gacctggaaacagatccacccaactggcagcagctcgttagcagagaagtgctactggga
ctgaaaccctccgagatcaagagacaggaagtgattaatgaattgttctacactgagaga
gcgcatgtccgaacactgaaggttcttgaccaagtattctatcagcgagtgtccagggaa
gggattctatcaccttccgagctgcgcaagattttttcaaacttggaggatatccttcaa
cttcatgttgggttgaatgagcagatgaaagctgtccgaaaaaggaacgagacctcagtt
attgatcatattggggaagatctgctcctttggttcagtggaccaggggaggagaagctg
aagcacgctgctgccacattctgcagtaaccagcctttcgccctggaaatgatcaagtct
cgccagaaaaaggattctcgattccagacttttgtgcaagatgctgagagtaaccccctg
tgccgtcgtcttcagctgaaggatatcattcccacccaaatgcagaggctcaccaagtac
ccccttcttttggataatatcgccaaatacacagaatggcctccagaaagggaaaaggtg
aagaaggctgcagatcaatgtcgtcagatcttaaattatgtaaatcaggctgtcagggag
gcagaaaacaagcagcgcttagaagactatcagcgtcgccttgacacctccagtctcaag
ttgtctgagtacccgaatgttgatgagctcaggaatttggatttaacaaaaagaaagatg
attcatgaagggccgttggtctggaaggtgaatagagataaaagcatcgatctgtataca
ctgctgctggaagacattcttgtgctgttacagaagcaggacgacaggctggtactgagg
tgccacagcaagatcctggcctccacagctgacagcaagcacaccttcagtcctgtcatt
aagctcagcacagtgctggtccgacaggtggccacagataacaaagctttattcgtcatc
tccatgtcagataatggagcccaaatttatgaattggtagcacagacggtttctgaaaag
acggtctggcaagacctcatctgtcggatggccgcatcagtgaaggagcagtccacaaag
ccgattcccctcccacagccgccaccttgcgaaggagacaatgatgaagaagaaccagcc
aagttaaaagtggagcaccatgatctttctgtcgctggtctgcagagtccagacagagtt
ttgggattagaatctcccttaatttcgtcaaaacctcagtcccattcaatgaatacccct
ggcaaatcagaggcagaacatctctttgtgaccgcaacacagtttgcaaaggagcagcat
gcaaatgggaccttcaaggaaggtgatggcgggtatccagtcacaatctcagatccacac
ttgcccgtgtcagaggagcggtgggcattggacgcactgagaaatttgggcttgttgaag
cagttgctggttcagcagttggggctcacggagaagactactcaggaagactggcggtcc
ttctcaagatacagaccggcttctgaagaggcacaggcggacagtggcattccggacttg
gaaagtgttaaggcttgtcatgccggggaaggacagatgtcttttaaaactggaactggt
gatgttgcaacttgtgacagtccacggacttcaactgagtcctgtgctgtacaggattcg
gtgatactggcttcccaagacagccaggcaagcaacatcatagaaatggaccacatgctc
ctgaccccagaggtgcctactactgcagagccagaggggggtctggatgacagtggagag
cacttttttgatgcccgtgaagcacatagcgatgataatccatctgaaggtgatggcgca
gtcagaaaggaagaggaggatgttaatgtgcgcatctcaggaaactgtttgatccttgat
ggctatgatgcagtgcaggagagctccacagatgaggagattgcctcctcattcaccctg
cagcctgtgacaggcctcccttctgtggactccagccaccagcagcaacactcccctcag
aatgccatttccgagggggcgatttcaccatccaccccagaattcctggtccagcgacgc
tggagagctgtggaggatgcttgctctgaggtccagagtccctctgcttggacagattca
caaagccaaatcctggagtacattcataaaatagaggctgacctggaacacttaaagaag
gtggaggaaagttacacccttctttgccaaaggctggctggctcagccctccccgacaag
gtctcagataaaagttag
DBGET
integrated database retrieval system
