Rattus norvegicus (rat): 432361
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Entry
432361 CDS
T01003
Symbol
Nrg2
Name
(RefSeq) pro-neuregulin-2, membrane-bound isoform
KO
K05456
neuregulin 2
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno04012
ErbB signaling pathway
rno05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
432361 (Nrg2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
432361 (Nrg2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
432361 (Nrg2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
rno04052
]
432361 (Nrg2)
Cytokines and neuropeptides [BR:
rno04052
]
Cytokines
Growth factors (RTK binding)
432361 (Nrg2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neuregulin
I-set
Ig_3
ig
Ig_2
Ig_6
V-set
C2-set_2
EGF
EGF_2
Motif
Other DBs
NCBI-GeneID:
432361
NCBI-ProteinID:
NP_001129623
RGD:
1303302
Ensembl:
ENSRNOG00000019093
UniProt:
O35569
D4A078
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All DBs
Position
18:complement(27890578..28072538)
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AA seq
860 aa
AA seq
DB search
MRQVCCSALPPPLEKARCSSYSYSDSSSSSSSNNSSSSTSSRSSSRSSSRSSRGSTTTTS
SSENSGSNSGSIFRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSML
LFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVL
DKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPVDPNGKNIKKE
VGKILCTDCATRPKLKKMKSQTGEVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIR
IKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARK
CNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQK
RVLTITGICVALLVVGIVCVVAYCKTKKQRRQMHHHLRQNMCPAHQNRSLANGPSHPRLD
PEEIQMADYISKNVPATDHVIRREAETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLE
RSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSQEERRRAAMPPYHDSIDSLR
DSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQ
QPLLRHPAPPGPGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPED
DEYETTQECAPPPPPRPRTRGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSG
CGSASASDDDADDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTR
ASSRHSRGPPTRAKQDSGPL
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atgcggcaggtttgctgctcagcgctgccgccgccactggagaaggctcggtgcagcagc
tacagctacagcgacagcagcagcagcagcagcagcaacaacagcagcagcagcaccagc
agcagaagcagcagcagaagcagcagcagaagcagcagaggcagcaccaccaccaccagc
agcagcgagaacagcggcagcaacagcggcagcatcttccgtcccgctgcgcccccagag
ccgcggccgcagccacagccgcagccccgcagccccgcagcccggagagccgccgcccgc
tcgcgagccgcagccgccggcggcatgaggcgcgacccggcccccggcttctcgatgctg
ctcttcggtgtgtcactcgcctgctactcgcccagcctcaagtccgtgcaggaccaggcg
tacaaggcacccgtggtggtggagggcaaggtacagggactggccccggcaggcggttcc
agctctaacagcacccgagagcctcccgcctcgggtcgggtggcgctggtgaaggtgctg
gacaagtggccgctccggagcggggggctgcagcgcgagcaggtgatcagcgtgggctcc
tgcgcgccgctcgaaaggaaccagcgctacatctttttcctggagcccaccgagcagccc
ttagtttttaagacagcctttgccccggtcgaccctaacggcaaaaacatcaagaaagag
gtgggcaagatcctgtgcactgactgcgcaacccggcccaagctgaagaagatgaagagt
cagacaggagaggtgggcgagaagcagtcgctcaagtgtgaggcggcggcggggaacccc
cagccctcctatcgatggttcaaggacggcaaggagctcaaccggagtcgtgacattcgc
atcaagtatggcaacggcagaaagaactcacggctacagttcaacaaagtgaaggtggag
gacgctggagagtacgtctgtgaggctgagaacatccttgggaaggacactgtgaggggc
cggctccatgtcaacagtgtgagcaccactctgtcgtcctggtcggggcacgcccggaag
tgcaatgagacagccaagtcctactgtgtgaatggaggcgtgtgctactacatcgaaggc
atcaaccaactctcctgcaaatgtccaaacggattcttcggacagagatgtttggagaaa
ctgcctttgcgattgtacatgccagatcctaagcaaaaggctgaggagctgtaccagaag
agagtcctgacaattaccggcatctgtgtggctctgctggtcgtgggcatcgtctgtgtg
gtcgcctactgcaagactaaaaaacagaggaggcaaatgcatcaccatctccggcagaac
atgtgtccggcccaccagaaccgaagcctggccaatgggcccagccaccctcggctggac
cctgaggagatccagatggcagattacatttccaaaaatgtgccagctacagaccatgtg
atccggagggaagctgagaccacattttctgggagccactcctgttcaccctctcaccac
tgttccacagccacacccacctccagccacagacatgagagccacacgtggagcttggaa
cgttcggagagcctgacctcggattcccagtcaggcatcatgctatcatcagtgggcacc
agcaagtgcaacagcccagcatgtgtggaggcacgggcacggagggcagcagcctacagc
caggaggagcgacgcagggctgccatgccaccctaccacgactccatagactcgctgcgt
gactccccacacagtgagaggtacgtgtcagccctgaccacgcccgcgcgcctttcgccc
gtggacttccactactcgctggccacccaggtgccgactttcgagatcacgtcgcccaac
tctgcccacgccgtgtcgctgccacccgcagcgcccatcagctaccgcctagcggagcag
cagccgctcctgcggcacccagcgccgcccggcccggggccagggcccggagcggacatg
cagcgcagctacgacagctactactacccggcggcggggcccgggccgcggcgcggcgcc
tgcgcgctgggaggcagtttgggcagcctgcccgccagccccttccgcatcccggaggac
gacgagtacgagaccacgcaggagtgcgcgcccccgccaccgccgcggccgcgcacgcgc
ggcgcgtcccgcaggacgtcggcggggccgcggcgctggcggcgctcccgcctcaacggg
ttggctgcgcagcgcgcacgcgcagcgcgggactcgctgtcgttgagcagcggttcgggc
tgcggctcggcgtcggcctcggacgacgatgcggacgacgcggacggggcgctggcggcc
gagagcacgcctttcctcggcctgcgagcggcgcacgacgcgctgcgctcggactcgccg
ccgctctgcccggcggcggacagcaggacttactactccctggacagccacagcacgcgc
gccagcagcagacacagccgggggccgcccacgagggcaaagcaggactccgggcccctc
taa
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