Rattus norvegicus (rat): 54226
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Entry
54226 CDS
T01003
Symbol
App
Name
(RefSeq) amyloid-beta precursor protein precursor
KO
K04520
amyloid beta A4 protein
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04726
Serotonergic synapse
rno05010
Alzheimer disease
rno05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
54226 (App)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
54226 (App)
05022 Pathways of neurodegeneration - multiple diseases
54226 (App)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rno01002
]
54226 (App)
09183 Protein families: signaling and cellular processes
00535 Proteoglycans [BR:
rno00535
]
54226 (App)
00536 Glycosaminoglycan binding proteins [BR:
rno00536
]
54226 (App)
Peptidases and inhibitors [BR:
rno01002
]
Peptidase inhibitors
Family I2: Kunitz - BPTI family
54226 (App)
Proteoglycans [BR:
rno00535
]
Cell surface proteoglycans
Others
54226 (App)
Glycosaminoglycan binding proteins [BR:
rno00536
]
Heparan sulfate / Heparin
Others
54226 (App)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
APP_E2
APP_N
APP_amyloid
APP_Cu_bd
Beta-APP
Kunitz_BPTI
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
54226
NCBI-ProteinID:
NP_062161
RGD:
2139
Ensembl:
ENSRNOG00000006997
UniProt:
P08592
A6JL62
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:complement(37506207..37724351)
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AA seq
770 aa
AA seq
DB search
MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTK
TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVG
EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
GVEFVCCPLAEESDSIDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEE
EAEDDEDVEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC
RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVSSQSLLKTTSEPLPQD
PVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
QAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN
IKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL
VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
NT seq
2313 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccagcctggcactgctcctgctggccgcctggacggttcgggctctggaggtg
cccactgatggcaatgccggtctgctggcagaaccccagatcgccatgttctgtggtaaa
ctcaacatgcacatgaatgtgcagaatggaaaatgggagtcagacccatcagggaccaaa
acctgcattggcaccaaggagggaatcctgcagtactgccaagaggtctaccctgaactg
cagatcacaaacgtggtggaagccaaccagccagtgaccatccagaactggtgcaagcgg
ggccgcaagcagtgcaagacgcacacccacatcgtgattccttaccggtgcctagttggt
gagtttgtaagcgatgcccttctcgtgcccgacaagtgcaagtttctacaccaggagcgg
atggacgtttgtgagacccatcttcactggcatactgttgccaaagagacatgcagtgag
aagagcactaacttgcacgactatggcatgctgctgccctgtggcatcgacaagttccga
ggggtcgagttcgtgtgctgcccgttggcggaggagagcgacagcatcgattctgcggac
gcagaggaggacgactccgatgtctggtggggtggagcggacacagactatgctgatggc
ggtgaagacaaagtcgtagaagtagccgaagaggaggaagtggccgatgttgaggaagaa
gaagctgaggatgacgaggatgtggaggatggggatgaggtggaggaggaggccgaggag
ccctacgaagaggccacagagagaacaaccagcattgccaccactaccacaactaccact
gagtctgtggaggaggtagtccgagaggtgtgctctgaacaagctgagaccgggccatgc
cgtgcaatgatctcccgctggtactttgatgtcactgaaggaaagtgcgccccattcttt
tacggcggatgtggcggcaacaggaacaactttgacactgaagagtactgcatggcggtg
tgtggcagcgtgtcatcccaaagtttactcaagactaccagtgaacctcttccccaagat
ccggttaaacttcccacgacggcagccagcacccctgacgcagtcgacaagtacctggag
acccccggagatgagaacgagcacgcccatttccagaaagccaaagagaggttggaagcc
aagcaccgagagagaatgtcccaggtcatgagagaatgggaggaggcagaacgtcaagcc
aagaatttgcccaaagctgacaagaaggccgttatccagcatttccaggagaaagtggaa
tctctggaacaggaagcagccaacgagaggcagcagcttgtagagacacacatggccaga
gttgaagccatgctcaatgatcgccgtcgcctggccctcgagaattacatcaccgcactg
caggcggtgcctccaaggcctcatcatgtgttcaacatgctgaagaagtacgtccgtgca
gagcagaaggacagacagcacaccctaaagcattttgaacatgtgcgcatggtggacccc
aagaaagctgctcagatccggtcccaggttatgacacacctccgtgtgatctacgagcgc
atgaaccagtctctgtccctgctctacaacgtccctgccgtggctgaggagattcaagat
gaagttgacgagctgcttcagaaggagcagaactactccgacgacgtcttagccaacatg
atcagtgaacccagaatcagttacggcaacgatgctctcatgccttctttgactgaaacg
aagaccactgtggagctccttcccgtgaatggcgaattcagcctggatgatctccaaccg
tggcatccttttggggtggactctgtgccagccaatacagaaaatgaagttgagcctgtc
gacgcccgccccgctgctgaccgaggactgaccactcgaccagggtctgggttgacaaac
atcaagacagaagagatctcagaagtgaagatggatgcggagttcggacatgattcaggc
ttcgaagtccgccatcaaaaactggtgttctttgcagaagatgtgggttcaaacaaaggt
gccatcattggactcatggtgggtggcgttgtcatagcaacagtgattgtcatcaccttg
gtgatgctgaagaagaaacagtacacatccatccatcatggcgtggtggaggttgacgct
gctgtgaccccggaggagcgccacctctccaagatgcagcagaatggatatgagaatcca
acatacaagttctttgagcagatgcagaactaa
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integrated database retrieval system
