Rattus norvegicus (rat): 54314
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Entry
54314 CDS
T01003
Symbol
Tpo
Name
(RefSeq) thyroid peroxidase precursor
KO
K00431
thyroid peroxidase [EC:
1.11.1.8
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00350
Tyrosine metabolism
rno01100
Metabolic pathways
rno04918
Thyroid hormone synthesis
rno05320
Autoimmune thyroid disease
Module
rno_M00043
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
54314 (Tpo)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
54314 (Tpo)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
54314 (Tpo)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8 iodide peroxidase
54314 (Tpo)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
An_peroxidase
EGF_CA
Sushi
EGF_3
FXa_inhibition
EGF
Plasmod_Pvs28
cEGF
Motif
Other DBs
NCBI-GeneID:
54314
NCBI-ProteinID:
NP_062226
RGD:
3900
Ensembl:
ENSRNOG00000004646
UniProt:
F1LN48
LinkDB
All DBs
Position
6:complement(52425998..52495793)
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AA seq
914 aa
AA seq
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MRTLGAMAVMLVVMGTAIFLPFLLRSRDILGGKTMTSHVINVVETSQLLVDNAVYNTMKR
NLKKRGVLSPAQLLSFSKLPESTSGAISRAAEIMETSIQVMKREQSQFSTDALSADILAT
IANLSGCLPFMLPPRCPDTCLANKYRPITGVCNNRDHPRWGASNTALARWLPPVYEDGFS
QPRGWNPNFLYHGFPLPPVREVTRHLIQVSNEAVTEDDQYSDFLPVWGQYIDHDIALTPQ
STSTAAFWGGVDCQLTCENQNPCFPIQLPSNSSRTTACLPFYRSSAACGTGDQGALFGNL
SAANPRQQMNGLTSFLDASTVYGSSPGVEKQLRNWSSSAGLLRVNTLHLDSGRAYLPFAS
AACAPEPGAPHANRTPCFLAGDGRASEVPALAAVHTLWLREHNRLATAFKAINTHWSANT
AYQEARKVVGALHQIITMRDYIPKILGPDAFRQYVGPYEGYNPTVNPTVSNVFSTAAFRF
GHATVHPLVRRLNTDFQDHTELPRLQLHDVFFRPWRLIQEGGLDPIVRGLLARPAKLQVQ
EQLMNEELTERLFVLSNVGTLDLASLNLQRGRDHGLPGYNEWREFCGLSRLETPAELNKA
IANRSMVNKIMELYKHADNIDVWLGGLAEKFLPGARTGPLFACIIGKQMKALRDGDRFWW
ENSHVFTDAQRQELEKHSLPRVICDNTGLTRVPVDAFRIGKFPQDFESCEEIPSMDLRLW
RETFPQDDKCVFPEKVDNGNFVHCEESGKLVLVYSCFHGYKLQGQEQVTCTQNGWDSEPP
VCKDVNECADLTHPPCHSSAKCKNTKGSFQCVCTDPYVLGEDEKTCIDSGRLPRASWVSI
ALGALLIGGLASLSWTVICRWTHADKKSTLLITERVTTESGFRKSQESGISPQKAEVQDA
EQEPAYGSRVLLCE
NT seq
2745 nt
NT seq
+upstream
nt +downstream
nt
atgagaacacttggagctatggcagtaatgctggttgtgatgggaactgcaattttcctc
cctttcctcctgagaagcagagacatcttgggggggaagactatgacatcccatgttatc
aatgttgtagaaacgagccagcttctggtggacaatgcagtctacaacaccatgaaaaga
aacctcaagaaaaggggagtcctttctccagcccagcttctctctttctccaagctgcca
gagtccaccagtggagctatttcccgagcagcagagatcatggaaacatcaatacaagtc
atgaaacgtgaacaatcacagttctccacggatgcactatcagcagacatcctggccaca
attgccaacctgtcaggatgcttgcctttcatgctgccaccgagatgtcctgacacctgc
ctggcaaacaagtaccggcccatcacaggggtgtgcaacaacagagatcaccccagatgg
ggagcctccaacacagccctagcaagatggctgcctcctgtctacgaagatggtttcagt
cagcccagaggctggaaccctaatttcttataccatggcttcccactgcccccggtacgg
gaggtgacaagacacctcattcaagtttcaaatgaggctgtgactgaagatgaccagtac
tctgattttctgccggtgtggggacagtacatcgatcatgacattgctctcacaccacag
agcaccagcacagcagccttctggggaggtgtcgactgccagttgacctgtgagaaccaa
aacccctgcttccccatacagcttccctcaaactcctcacggaccactgcatgcctacct
ttctaccgctcctcagccgcctgtggcactggggaccaaggagcactctttggcaacctg
tctgcagccaatccgaggcagcagatgaatggcttgacctccttccttgatgcttccacg
gtgtatggcagctccccaggtgttgagaagcagttgcgcaactggagcagctctgcaggg
ctgctgcgtgtcaacaccctccacctagactctggccgtgcctacctgcccttcgcatca
gccgcctgtgctccagagcctggtgctccacacgccaaccgcacgccctgcttcctggct
ggtgatggccgcgccagcgaggtccccgccctggcagcagtgcacaccttgtggctgcgc
gagcacaaccgcctggctacagctttcaaagccatcaacacacattggagcgccaacact
gcctaccaggaggcacgcaaggtggtaggggcattgcaccagatcatcaccatgagggat
tatatccccaagatcctgggtcccgatgccttcaggcagtatgtgggcccctatgaaggc
tataaccccacggtgaaccctactgtgtccaacgtcttctctactgctgccttccgcttt
ggccatgccacagtccatccactggtgagacgactaaacacagacttccaggaccacaca
gagctccccaggctgcagctgcacgacgtcttcttcaggccctggaggcttatccaggaa
ggtggtttggatccaatagtaagaggcctcctggcaagaccagccaagctgcaagtacag
gagcaactgatgaatgaggaactgaccgagaggctctttgtgttgtctaatgtgggcacc
ttggatctggcatcactgaacttgcagaggggccgggaccacggcttaccaggctacaat
gagtggagagagttctgtggcttgtcacgcctggagacaccagctgagctgaacaaggcc
attgccaacagaagcatggtcaacaagataatggagttatacaagcatgctgacaacatt
gatgtctggttgggaggcctggctgaaaagttcttaccgggagcccgcaccggtcctctg
tttgcatgtatcattgggaagcagatgaaggctctgagggatggggacaggttttggtgg
gagaacagccatgtcttcacagacgctcagaggcaggaactggaaaagcattcactacct
cgggtcatctgtgacaacaccggcctcaccagagtacctgtggatgccttccgtattgga
aagttcccccaggactttgaatcctgtgaggaaatccctagcatggacctcagactgtgg
agggagaccttcccacaagacgacaagtgtgtcttcccagagaaggtggacaatgggaac
tttgtgcactgtgaagaatctgggaagctggtactggtgtattcctgtttccatggatac
aagctgcaaggccaggagcaggtcacatgtacccagaatggatgggactcagagcctcct
gtctgtaaagatgttaatgagtgtgcagatctgacacacccaccttgccactcctccgca
aagtgcaagaacaccaagggaagcttccagtgtgtgtgcacagacccctacgtgctaggt
gaggatgagaagacctgcatagattctggcaggctacctcgggcatcctgggtctccatt
gcattgggtgcacttctcattggtggtttggccagtctcagctggactgtaatttgcagg
tggacacatgctgataagaagtccacattgctgatcaccgagagagtgaccacggagtca
ggattcagaaagagtcaggagagtgggatttcaccacaaaaggccgaggttcaagatgct
gaacaggaaccggcttatggatccagagtcctcctgtgtgaatag
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