Rattus norvegicus (rat): 59077
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Entry
59077 CDS
T01003
Symbol
Grk4
Name
(RefSeq) G protein-coupled receptor kinase 4
KO
K08291
G protein-coupled receptor kinase [EC:
2.7.11.16
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04062
Chemokine signaling pathway
rno04144
Endocytosis
rno05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
59077 (Grk4)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
59077 (Grk4)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
59077 (Grk4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
59077 (Grk4)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.16 G-protein-coupled receptor kinase
59077 (Grk4)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
59077 (Grk4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
59077
NCBI-ProteinID:
NP_075217
RGD:
61858
Ensembl:
ENSRNOG00000011847
UniProt:
P70507
A6IK17
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All DBs
Position
14:complement(80230699..80305292)
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AA seq
575 aa
AA seq
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MELENFMANTLLLKARQGFTKKTGRSKKWRELLKLPPVSMCSDLRHSIEKDFSSLCDQQP
IGRLLFRQFCNTKPDLKRCIEFLDAAAEYEVTIEEEQREFGLSIYSRFFKENSEVSLPQI
PPDLVKECKCNLKQSSPSQNVFQDCAGVIYKYLSEKPFEEYQESTYYNRFLQWKWLERRP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEK
LHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGNPGFEEQRAVFYAAELCCGLE
DLQRERIVYRDLKPENILLDDHGHIRISDLGLALEIPEGEMVRGRVGTVGYMAPEIISHE
KYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREEMERRVKTETEEYSERFSENAKSIC
SMLLTKDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPPFCPDPEAIYCKDILDI
GQFSVVKGVNLDTNDEIFYTQFATGCVTIPWQNEMIESGCFKDLNEYEDKGLSPLEKHKI
CSCILRPKRNFFHRLFRRAACLNIAHSEEREPTEH
NT seq
1728 nt
NT seq
+upstream
nt +downstream
nt
atggaactggagaacttcatggccaacactttgttgctgaaggctcgtcaaggatttacc
aaaaagactggtcgcagtaaaaagtggagagagctcctgaagttgcccccagtcagcatg
tgcagtgacttacgacactccatcgaaaaggattttagcagtctttgtgaccaacagcca
atcggaagacttcttttcagacaattctgtaatacgaaaccagatctaaagaggtgcatt
gaattcttggatgcagcggcagagtatgaagttaccatcgaagaggaacaaagagaattt
ggactatccatctacagtagattcttcaaagagaattcagaagtctccttaccacagata
cctccagatcttgtgaaggagtgtaaatgcaatctgaagcagagttctccctctcaaaat
gtgttccaggactgtgctggagttatctataagtatttgagtgaaaaaccatttgaagaa
taccaagagagtacatactataatcgatttttacaatggaaatggctagaaaggcgtcca
gtaacaaagaacacattcagacaatacagagttttaggaaaaggcggatttggagaggtt
tgtgcctgtcaagtgcgagctacaggaaaaatgtatgcctgcaaaaaactagaaaaaaaa
agaataaagaagaggaaaggtgaagccatggctctgaatgaaaaaagaatcttagaaaaa
ttgcatagtagatttgtagttagtttagcctacacttatgaaaccaaggatgctttgtgt
ttggtgctaaccattatgaatggaggggatttgaagtaccacatttacaacctgggcaat
cctggctttgaggagcagagagctgtgttctatgctgcagagctgtgctgtggcttggaa
gatttacagagggaaagaattgtatacagagacctaaaaccagagaatatcctccttgat
gatcatggacacatccgaatttcagatcttggtctagctctggaaatcccagaaggggag
atggttcgaggaagagttggtactgttggctacatggctccagaaattatcagtcatgaa
aagtatacatttagtcctgattggtggggacttggctgtctgatatatgaaatgattgcg
ggacattctccattcagaaaatataaagaaaaagtcaaccgggaggaaatggaaagaaga
gtgaagactgaaactgaggagtactctgagaggttttcagagaatgccaagtccatctgc
agcatgttacttaccaaggatccaagtaaaaggctgggctgccagagtgatggagcctct
gctgtaaagcagcacccaatattcaaggatattaacttcagcagactggaagcaaatatg
ttagacccacctttctgtcctgatcctgaggccatttattgtaaggatatcttggatatt
ggacagttctctgtggtgaaaggagtcaacctggacaccaatgatgagatcttctacact
caatttgcgacagggtgtgtcaccattccctggcagaatgagatgattgaatctggatgt
ttcaaggacctcaatgaatatgaagataaaggtctgtcaccacttgaaaaacacaagata
tgttcctgtattcttagaccaaagagaaacttcttccatagactcttcagaagagcggcc
tgcctgaacattgcccacagtgaggagagggagccaacagaacactga
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