Rattus norvegicus (rat): 60445 Help Entry 60445             CDS       T01003                                  Symbol Tsc1 Name (RefSeq) hamartin   KO K07206   tuberous sclerosis 1 Organism rno  Rattus norvegicus (rat) Pathway rno04072   Phospholipase D signaling pathway rno04140   Autophagy - animal rno04150   mTOR signaling pathway rno04151   PI3K-Akt signaling pathway rno04152   AMPK signaling pathway rno04211   Longevity regulating pathway rno04218   Cellular senescence rno04714   Thermogenesis rno04910   Insulin signaling pathway rno05163   Human cytomegalovirus infection rno05165   Human papillomavirus infection rno05168   Herpes simplex virus 1 infection rno05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     60445 (Tsc1)    04151 PI3K-Akt signaling pathway     60445 (Tsc1)    04152 AMPK signaling pathway     60445 (Tsc1)    04150 mTOR signaling pathway     60445 (Tsc1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     60445 (Tsc1)   09143 Cell growth and death    04218 Cellular senescence     60445 (Tsc1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     60445 (Tsc1)   09149 Aging    04211 Longevity regulating pathway     60445 (Tsc1)   09159 Environmental adaptation    04714 Thermogenesis     60445 (Tsc1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     60445 (Tsc1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     60445 (Tsc1)    05163 Human cytomegalovirus infection     60445 (Tsc1)    05165 Human papillomavirus infection     60445 (Tsc1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hamartin ATG16 Motif Other DBs NCBI-GeneID:  60445 NCBI-ProteinID:  NP_068626 RGD:  620124 Ensembl:  ENSRNOG00000011470 UniProt:  Q9Z136 LinkDB All DBs Position 3:11969547..12018591 Genome browser AA seq 1163 aa AA seqDB search MAQLANIGELLSMLDSSTLGVRDDVTTIFKESLNSERGPMLVNTLVDYYLETNSQPVLHI LTTLQEPHDKHLLDKMNEYVGKAATRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCL KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEVYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENVETFEEVVKPMMEHVRIHPELVTGSKDH ELDPRRWKTLETHDVVIECAKISLDPTEASYEDGDAVSHQLSACFPHRSADVTTSSYVDT QNSYGGATSTPSSTSRLMLFSTPGQLPQSLSSLSTRPLPEPLQASLWSPSAVCGMTTPPT SPGNVPADLSHPYSKAFGTTTGGKGTPSGTPATSPPPAPPCPQDDCAHGPASQASATPPR KEERADSSRPYLPRQQDVPSDRGLEDLPGSKGSVTLRNLPDFLGDLASEEDSIEKDKEEA AISKELSEITTAEADPVAPRGGFDSPFYRDSLSGSQRKTHSAASGTQGFSVNPEPLHSSL DKHGPDTPKQAFTPIDPPSGSADASPAGDRDRQTSLETSILTPSPCKIPPQRGVSFGSGQ LPPYDHLFEVALPKTACHFVSKKTEELLKKAKGNPEEDCVPSTSPMEVLDRLLEQGAGAH SKELSRLSLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL RKVIRAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYSQLQQQRDTMVTQLHSQIR QLQHDREEFYNQSQELQTKLEDCRSMIAELRVELKKANSKVCHTELLLSQVSQKLSNSES VQQQMEFLNRQLLVLGEVNELYLEQLQSKHPDTTKEVEMMKTAYRKELEKNRSHLLQQNQ RLDASQRRVLELESLLAKKDHLLLEQKKYLEDVKSQASGQLLAAESRYEAQRKITRVLEL EILDLYGRLEKDGRLQKLEEDRAEAAEAAEERLDCCTDGCSDSLLGHNEEAAGHNGETRT SRPGGTRASCGGRVTGGSSSSSSELSTPEKPPNQRFSSRWEPTMGEPSSSIPTTVGSLPS SKSFLGMKTRELFRNKSESQCDEDGMTMSSFSETLKTELGKDSAGMENKTPPSLDAPHPS SPSSDSMGQLHIMDYNETHHEHS NT seq 3492 nt NT seq  +upstreamnt  +downstreamnt atggcccagctagccaacattggggagctactctccatgctggactcttccacactgggt gtgcgtgatgacgtgacaaccatcttcaaggagtccctcaattctgaacgtgggcctatg cttgtaaacacgttggtggattattacctggaaaccaattctcagccggtcttgcacatc ctgaccaccctgcaagagccacatgataagcacctcttggacaaaatgaatgagtatgta ggcaaagctgccacccgcttatccatcctctcgctgctggggcatgttgtgaggctgcag ccatcttggaagcataagctctctcaagcacctcttctgccttctttactgaaatgtctc aagatggacactgatgttgtggttctcacaactggtgtcttggtgttgatcaccatgcta ccgatgatcccgcagtcagggaagcagcaccttctcgacttctttgacatctttggccgt ctttcatcatggtgcctgaagaaaccaggccatgtgacagaagtctacctggtccacctc catgccagtgtttatgccctcttccatcgcctttatggaatgtacccttgtaacttcgtc tccttcctgcgctctcactacagcatgaaggaaaacgtggagacttttgaagaagtggtc aagccaatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccat gaactggaccctcgaaggtggaagacattagaaactcatgatgttgtaatagagtgtgcc aaaatctctctggaccctaccgaagcctcatatgaagatggcgatgctgtgtctcaccag ctctctgcctgcttccctcaccgttcagctgatgtcaccaccagctcttacgtggacaca cagaatagctatgggggcgctacttccaccccttcctccacctctcggctgatgttgttc agtacccccgggcagctacctcagagtttgagttcactatcaacacggccgttacctgag ccgctgcaagctagtctttggagcccatctgcagtctgtggtatgaccactcctcctacg tctcctggaaatgtcccggctgatttgtcacatccatacagtaaagcctttggtactacc actggtggaaaaggaactccttcaggaaccccagcgacctctcctcccccagccccgcct tgtccccaagacgactgtgcgcacggtccagcctcccaggcctcagccacaccccccagg aaggaagaaagagcagattcttcaaggccttacctacccagacagcaggatgttccgagt gaccgcggattagaggatctacctggaagcaaaggttccgtcactctgaggaatctacca gatttcctaggtgacctggcttcagaggaagacagtatagagaaagataaggaagaagct gcgatatctaaagagctttctgagatcaccactgcagaggcggatcctgtagctcctcga gggggctttgactctcccttctaccgagacagtctctctggttctcagcggaagactcac tcagcagcctctgggactcagggcttcagcgtgaaccctgagcctttgcactcctccctg gacaaacatgggcctgacacaccaaagcaagcctttactcccatagacccaccctctggc agtgctgatgccagtcccgctggggacagggatcgccagacttctctggagaccagtatc ctcactcccagcccttgcaaaattccacctcagaggggagtgagctttggaagtgggcag cttcccccatatgatcatctctttgaggtggccttgccaaagactgcctgtcactttgtc agcaaaaagactgaagagctgttgaagaaagcgaaaggaaaccctgaggaagactgtgtg ccctctacctccccaatggaagtactggacagactgctagagcagggagcaggggcacac agcaaggaactgagcaggttgtccttgcccagcaagtctgttgactggacccactttgga ggctctcccccctcagatgagatccggaccctccgagaccagttgctcttactgcacaat cagctgctgtacgaacgctttaagcggcagcagcatgcactgaggaacagaaggctgctg cgcaaggtgatccgagctgcggccctggaggagcacaacgcagcgatgaaagatcagttg aagttacaagagaaggacatccagatgtggaaggtgagtctgcagaaagaacaagcccga tacagtcagcttcagcaacaacgtgacaccatggtgacccagctgcatagccaaatcaga cagctgcagcatgaccgagaagaattctacaaccagagtcaggagttacagacgaagctg gaggactgcagaagcatgatcgcggagcttcgagtggagctgaagaaggccaacagcaag gtgtgccacaccgagctgctgctcagccaggtctctcagaagctctccaatagtgagtca gtgcagcagcagatggagttcttgaataggcagctcctggtgctcggggaggtcaatgag ctgtacctggagcagctgcagagcaagcatcctgacaccaccaaggaagtagaaatgatg aaaactgcttatcggaaagaactagagaaaaacagaagccaccttctccagcagaaccag aggctggatgcctcacagaggcgagttttagaactggaatctcttctggccaagaaagac caccttctcctagagcagaagaagtaccttgaggatgtcaagagccaggcgagtggacag ctgctggctgcagagagcaggtatgaggctcagagaaagatcacccgggtgttggaactg gagatcctagacttgtatggtagattggagaaagatggccgcctacagaaactagaagag gacagagcagaggcagcagaggcagctgaagagaggcttgactgttgtactgatggatgc tcagattccttgttaggacataatgaagaggctgctggtcacaatggtgagaccaggacc tccagacctggtggcacccgggccagctgtggaggtagagtcactggaggcagcagcagc agcagcagtgagctttccactccagagaaacccccgaaccagaggttcagcagccggtgg gagcccaccatgggtgagccctccagcagcatccccaccactgttggctcacttcccagt tccaaaagcttcttgggcatgaagacccgggagctgttccgtaataagagtgagagccag tgtgatgaggatggcatgaccatgagtagcttttctgagaccctgaagacagaactgggc aaagactcggcgggcatggaaaacaagactcccccaagtctagacgccccacacccatct tccccaagctcagacagtatggggcagctccatatcatggactacaatgagactcatcac gaacacagctga

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