KEGG   Rattus norvegicus (rat): 65162
Entry
65162             CDS       T01003                                 
Symbol
Dio2
Name
(RefSeq) type II iodothyronine deiodinase
  KO
K17904  type II thyroxine 5'-deiodinase [EC:1.21.99.4]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04081  Hormone signaling
rno04919  Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    65162 (Dio2)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    65162 (Dio2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.21.99  With unknown physiological acceptors
    1.21.99.4  thyroxine 5'-deiodinase
     65162 (Dio2)
SSDB
Motif
Pfam: T4_deiodinase AhpC-TSA Redoxin Thioredoxin_8 DUF2284
Other DBs
NCBI-GeneID: 65162
NCBI-ProteinID: NP_113908
RGD: 68418
Ensembl: ENSRNOG00000062383
UniProt: P70551
LinkDB
Position
6:complement(115396308..115410594)
AA seq 262 aa
MGLLSVDLLITLQILPVFFSNCLFLALYDSVILLKHVALLLSRSKSTRGEWRRMLTSEGL
RCVWNSFLLDAYKQVKLGEDAPNSSVVHVSNPEAGNNCASEKTADGAECHLLDFASAERP
LVVNFGSATUPPFTRQLPAFRQLVEEFSSVADFLLVYIDEAHPSDGWAVPGDSSMSFEVK
KHRNQEDRCAAAHQLLERFSLPPQCQVVADRMDNNANVAYGVAFERVCIVQRRKIAYLGG
KGPFSYNLQEVRSWLEKNFSKR
NT seq 789 nt   +upstreamnt  +downstreamnt
atgggactcctcagcgtagacttgctgatcactcttcagattctgccagtctttttctcc
aactgcctcttcctggcgctctatgactcggtcattctgctcaagcacgtggcgctgctt
ctcagccgctccaagtccactcgcggagagtggaggcgcatgctgacctcagaaggacta
cgctgtgtctggaacagctttctcctagacgcctacaaacaggttaaattgggtgaagat
gctcccaattccagtgtggtgcacgtgtccaatcctgaagcaggtaacaattgtgcctca
gagaagacggcggatggggctgaatgccaccttcttgactttgccagtgcagagcgccca
ctggtggtcaactttggttcagcgacctgaccaccttttactaggcaactgccagccttc
cgccagttggtggaagagttctcctcggtggctgacttcctgttggtatacattgatgag
gctcacccttcagatggctgggcagtgcctggggactcctctatgtcttttgaggttaag
aagcaccggaaccaagaggaccgatgtgctgcagcccaccagctcctggagcgtttctcc
ttgccgccccagtgtcaagttgtggctgaccgcatggacaataatgccaacgtagcttat
ggggtagcctttgaacgtgtgtgcatcgtgcagagacggaaaattgcttacttaggaggg
aagggccccttcagctataacctgcaagaagtccgaagttggctggagaagaatttcagc
aagagatga

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