Rattus norvegicus (rat): 682930
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Entry
682930 CDS
T01003
Symbol
Cacna1s
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04010
MAPK signaling pathway
rno04020
Calcium signaling pathway
rno04022
cGMP-PKG signaling pathway
rno04024
cAMP signaling pathway
rno04260
Cardiac muscle contraction
rno04261
Adrenergic signaling in cardiomyocytes
rno04270
Vascular smooth muscle contraction
rno04723
Retrograde endocannabinoid signaling
rno04725
Cholinergic synapse
rno04726
Serotonergic synapse
rno04727
GABAergic synapse
rno04911
Insulin secretion
rno04912
GnRH signaling pathway
rno04921
Oxytocin signaling pathway
rno04924
Renin secretion
rno04925
Aldosterone synthesis and secretion
rno04927
Cortisol synthesis and secretion
rno04929
GnRH secretion
rno04934
Cushing syndrome
rno04935
Growth hormone synthesis, secretion and action
rno05010
Alzheimer disease
rno05020
Prion disease
rno05022
Pathways of neurodegeneration - multiple diseases
rno05207
Chemical carcinogenesis - receptor activation
rno05410
Hypertrophic cardiomyopathy
rno05412
Arrhythmogenic right ventricular cardiomyopathy
rno05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
682930 (Cacna1s)
04020 Calcium signaling pathway
682930 (Cacna1s)
04024 cAMP signaling pathway
682930 (Cacna1s)
04022 cGMP-PKG signaling pathway
682930 (Cacna1s)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
682930 (Cacna1s)
04929 GnRH secretion
682930 (Cacna1s)
04912 GnRH signaling pathway
682930 (Cacna1s)
04921 Oxytocin signaling pathway
682930 (Cacna1s)
04935 Growth hormone synthesis, secretion and action
682930 (Cacna1s)
04924 Renin secretion
682930 (Cacna1s)
04925 Aldosterone synthesis and secretion
682930 (Cacna1s)
04927 Cortisol synthesis and secretion
682930 (Cacna1s)
09153 Circulatory system
04260 Cardiac muscle contraction
682930 (Cacna1s)
04261 Adrenergic signaling in cardiomyocytes
682930 (Cacna1s)
04270 Vascular smooth muscle contraction
682930 (Cacna1s)
09156 Nervous system
04727 GABAergic synapse
682930 (Cacna1s)
04725 Cholinergic synapse
682930 (Cacna1s)
04726 Serotonergic synapse
682930 (Cacna1s)
04723 Retrograde endocannabinoid signaling
682930 (Cacna1s)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
682930 (Cacna1s)
09164 Neurodegenerative disease
05010 Alzheimer disease
682930 (Cacna1s)
05020 Prion disease
682930 (Cacna1s)
05022 Pathways of neurodegeneration - multiple diseases
682930 (Cacna1s)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
682930 (Cacna1s)
05412 Arrhythmogenic right ventricular cardiomyopathy
682930 (Cacna1s)
05414 Dilated cardiomyopathy
682930 (Cacna1s)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
682930 (Cacna1s)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
rno04040
]
682930 (Cacna1s)
Ion channels [BR:
rno04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
682930 (Cacna1s)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
682930
NCBI-ProteinID:
NP_446325
RGD:
70983
Ensembl:
ENSRNOG00000046231
UniProt:
Q02485
LinkDB
All DBs
Position
13:50045668..50115903
Genome browser
AA seq
1850 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISVVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTAILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRV
FRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFMIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSRGLPDKSEEERSTMTKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPASPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFT
AVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDL
SKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMILKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILS
EIDTLLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKRCDPESDYAPGEEYACGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFAEMEMEELESPVFLEDFPQNPGTHPLARANTNNANANVAYGNSSHRNSPV
FSSIRYERELLEEAGRPVTREGPFSQPCSVSGVNSRSHVDKLERQMSQRRMPKGQVPPSP
CQLSQEKHPVHEEGKGPRSWSTETSDSESFEERVPRNSAHKCTAPATTMLIQEALVRGGL
DSLAADANFVMATGQALADACQMEPEEVEVAATELLKRESPKGGAMPREP
NT seq
5553 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgagggcctgaggaagaagcagcctaagaaacccgtc
cctgagattctgccgaggccaccccgggccttgttctgcttgactctccagaaccccctg
aggaaggcctgcatcagcgtcgtggagtggaaacccttcgagaccatcatcttgctcacc
atcttcgccaactgtgtggccctggcagtgtacctgcccatgccagaggatgacaacaac
actctgaaccttggcctggagaaactggagtacttcttcctcatcgtcttctccattgag
gctgctatgaagatcatagcctatggcttcctattccatcaggatgcttacctgcgcagt
ggctggaacgtgctggacttcatcattgtctttctgggtgtcttcaccgcgattctggaa
caagttaacatcattcaaaccaacacggcccccatgagcagcaaaggagccggcttggat
gtgaaggccctgcgagctttccgcgtgctcagacccctgcggctggtgtcaggggtgccc
agccttcaggtagtcctcaactccatcttcaaggccatgctccccctgttccacatcgcc
ctgctcgtcctcttcatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aagatgcacaagacgtgctacttcattgggacagacatcgtggccacagtagagaatgag
aaaccatcaccctgtgctagaactggctccgggcgcccctgcaccatcaacggcagcgag
tgccgaggaggttggccaggacccaaccatggcatcacccacttcgacaactttggcttc
tctatgctcactgtgtaccagtgcatctccatggaggggtggaccgatgtcctgtactgg
gtcaatgatgccatcgggaacgagtggccctggatctactttgtcaccctcattctgctg
ggctccttcttcatcctgaacctggtgctgggtgtcctgagtggagaattcaccaaggag
cgagagaaggccaagtccagaggaaccttccaaaagctccgggagaagcagcagctggag
gaagaccttcgtggttacatgagttggatcacacagggcgaggtcatggacgtggacgac
ttgagagaaggcaagctgtctttggatgaagggggctcggatacagagagcttatatgaa
atcgagggcttgaacaaaatcatccaattcattcggcactggcggcagtggaatcgcgtc
ttccgctggaagtgccatgacctagtgaaatccaaggtcttctattggctggtgatcctg
attgtggccctcaacaccctgtccattgcctcagagcaccacaaccagccactctggctg
acgcatttgcaagatgtcgccaaccgcgtgctgctggccctcttcaccatcgagatgctc
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagatcttgctggtggagtcgggagccatgacg
cccctgggcatctctgtgctccgctgcatccgcctcctgaggctcttcaagatcaccaag
tactggacatcgctgagcaacctggtggcctcgctgctcaactccatccgctctatcgct
tccctcttgctgctgctctttcttttcatgatcatctttgccctgctaggcatgcagctc
tttggaggcagatacgactttgaagacacggaagtacgacgaagcaactttgacaacttc
ccccaggccctcatcagtgtcttccaggtcctgacgggtgaagactggaactctgtgatg
tacaatgggatcatggcctacggaggcccgtcctaccctggcgtgctcgtgtgcatttat
ttcatcatcctttttgtctgtggtaactacatccttctcaatgtcttcctggctatcgct
gtggacaacctggcagaggctgagagcctgacatctgcccagaaggccaaggctgaggag
agaaagcgcaggaagatgtctagagggctcccagacaagtcagaagaggagagatccaca
atgaccaagaagctggagcagaaacccaagggtgaaggcatccccaccactgccaagctg
aaaatcgatgagtttgaatcgaacgtcaatgaggtgaaagacccctacccttcagctgac
ttcccaggggacgacgaggaagatgagcctgagatcccagcaagcccccgaccacgccct
ctggctgagctgcagctgaaagagaaagcggtgcccatcccagaggccagctccttcttc
atcttcagccccaccaataagatccgcgtcctatgtcaccgcattgtcaacgccacctgg
ttcaccaactttatcctactcttcatcctgctcagtagtgctgctctggccgctgaggac
cccatccgggccgactccatgaggaatcagatccttgagtattttgattatgtgttcact
gctgttttcactgtggagatcgtccttaagatgaccacctatggagccttcctgcacaaa
ggctccttctgccgcaactacttcaacatcctggacctgctggtagtggctgtgtctctc
atctccatgggcctcgagtccagcgccatctccgtggtgaagatcttgagggtcctgagg
gtgttgcgaccactccgggccataaacagagccaaagggttgaagcacgtggtgcagtgc
gtgtttgttgctatccgcaccatcgggaacatcgtgctggtcaccacgctcctgcagttc
atgtttgcatgcatcggagtccagcttttcaagggaaaattctacagctgcaatgattta
tccaagatgactgaagaggagtgcaggggctactactacatatacaaggatggagacccc
acgcagatagagttgcgaccccgtcagtggatacacaatgacttccactttgacaatgtc
ctgtctgctatgatgtcactcttcacggtctccacctttgagggttggcctcagctactg
tacaaggccatagactccaatgaggaggacacaggccccgtctacaacaaccgagtggag
atggccatcttcttcatcatctacatcattctcatcgccttcttcatgatgaacatcttt
gtgggcttcgtcatcgtcaccttccaggagcagggggagactgagtataagaactgtgag
ctggacaagaaccagcgccaatgtgtgcagtatgccctgaaggcccgcccgctgaggtgt
tacatccccaaaaacccataccagtatcaggtgtggtatgtcgtcacttcctcctacttt
gaatacctgatgtttgctctcatcatgctcaacactatctgcctaggcatgcagcattac
aaccagtcggaacagatgaaccacatatcggacatcctcaatgtggctttcaccatcatc
ttcaccctggagatgatcctcaagctcatagctttcaagcccaggggctattttggagac
ccctggaacgtgtttgactttctaatcgtcattggcagcatcattgacgttatcctgagt
gagatcgatactttgctggcctccagcgggggactatattgcctgggtggaggctgcggg
aacgttgacccagatgagagcgcccgcatctccagtgccttcttccgcctgttccgagtc
atgcgactgatcaagctgctgagccgggcggagggtgtgcgcaccctgctctggacgttc
atcaagtccttccaggccctgccgtatgtggctttgctgatcgtcatgctcttcttcatc
tacgctgtcatcggcatgcagatgttcgggaagatcgccatggtggacgggacgcaaata
aaccggaacaacaacttccagactttcccacaagctgtgctgctgctcttcaggtgtgcc
acaggggaagcctggcaggagatcctgctggcctgcagctacgggaaacgctgcgacccg
gagtctgactacgcaccgggggaggagtacgcgtgtggcaccaactttgcctactactac
ttcatcagcttctacatgctctgcgccttcctgatcatcaacctctttgtggctgtcatc
atggacaactttgactacctcacaagggactggtccattctgggccctcaccacctggat
gagttcaaggccatctgggctgagtacgacccagaggctaagggcaggatcaagcacctg
gacgtggtgaccctgctgaggaggatccagccccctctgggctttgggaagttctgccca
cacagggtagcatgtaagaggctggtgggcatgaacatgcccctgaatagtgatggcaca
gtcaccttcaatgccacactcttcgccctggtacgcacagccctcaagatcaagacagaa
ggcaattttgaacaagccaatgaggagctgagagccatcatcaaaaagatctggaagaga
accagcatgaagctcctggaccaagtcatccctccaataggagatgacgaggtgacagtg
gggaagttctatgccacattcctcatccaggagcactttcggaagttcatgaagcgccag
gaggaatattatgggtatcgacccaaaaaggacacagttcagatacaggctggattgcgg
accatagaggaagaggcagctcctgagatccaccgagccatctctggagacctgacggcg
gaggaggagctggagagggccatggtagaggctgccatggaggaggggatattccggaga
actggaggcctgtttggtcaagtggacaacttcctggaaaggaccaactctctgccccct
gtcatggctaaccaaagacccctccaatttgccgaaatggagatggaagagctggagtca
ccagtctttttggaggacttccctcagaacccaggcacccaccctcttgctcgtgccaat
accaacaacgccaatgccaatgttgcctatggcaacagcagccatagaaacagcccagtg
ttttccagcatccgctatgaaagggagctcctggaagaggcaggcaggcctgttaccaga
gaaggacccttcagtcagccctgcagcgtctctggagttaacagcagatcccatgtggac
aaactggaaagacagatgtcccaaagaagaatgcccaaaggccaggtgcctccttcccca
tgccagctctcccaggaaaagcatcctgtgcacgaagaggggaagggccccaggtcatgg
tctacggaaacatctgacagtgagagctttgaggagcgtgttcccaggaattcggctcac
aagtgcacagccccagctaccaccatgctgatccaggaggctctggttcgaggaggacta
gactccttagcagcagatgctaacttcgtcatggcaacaggccaggccctggcagatgcc
tgccagatggaaccagaggaagtcgaggtggcagcaacagagctactgaagcgagaatcc
ccaaagggcggggccatgcccagggagccttga
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integrated database retrieval system
