Rattus norvegicus (rat): 79238
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Entry
79238 CDS
T01003
Symbol
Hmgcl
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial precursor
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00280
Valine, leucine and isoleucine degradation
rno00650
Butanoate metabolism
rno01100
Metabolic pathways
rno04146
Peroxisome
Module
rno_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
79238 (Hmgcl)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
79238 (Hmgcl)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
79238 (Hmgcl)
Enzymes [BR:
rno01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
79238 (Hmgcl)
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GFIT
Motif
Pfam:
HMGL-like
Motif
Other DBs
NCBI-GeneID:
79238
NCBI-ProteinID:
NP_077362
RGD:
620554
Ensembl:
ENSRNOG00000009422
UniProt:
P97519
A6IT78
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Position
5:153461738..153475552
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AA seq
325 aa
AA seq
DB search
MATVRKAFPQRLVGLASLRAASTSSMGTLPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLI
DMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAG
AKEVSIFGAASELFTRKNVNCSIEESFQRFDGVMQAARAASISVRGYVSCALGCPYEGKV
SPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVLHEVPVAALAVHCHDTYGQ
ALANTLVALQMGVSVVDSSVAGLGGCPYAKGASGNLATEDLVYMLTGLGIHTGVNLQKLL
EAGDFICQALNRKTSSKVAQATCKL
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcgacagtgaggaaggctttcccacagaggctggtgggcttggcgtccctccgggct
gcgagcacctcctccatgggcaccttgccgaagcgggtgaagatcgtggaagtcggcccc
cgagatggtctgcagaatgaaaagagtatcgtgccgacgccagtgaaaatcaaactgata
gacatgctatccgaagcagggctcccggtcatcgaggccaccagctttgtctctcccaag
tgggtgccgcagatggctgaccactctgacgtcttgaagggcattcagaagtttcccggc
atcaactacccggtcctgacaccaaacatgaaaggctttgaggaagcggtagctgcaggt
gccaaggaagtgagcatctttggggctgcgtccgagctcttcacccggaagaatgtgaac
tgctctatagaggagagtttccagcgctttgatggggtcatgcaggccgcgagggctgcc
agcatctctgtgagagggtatgtctcctgtgccctcggatgtccctacgaggggaaggtc
tccccggctaaagttgctgaggtcgccaagaagttgtactcaatgggctgctatgagatc
tcccttggggacaccattggcgtaggcacgccaggactcatgaaagacatgctgactgct
gtcctgcatgaagtgcctgtggccgcattggctgtccactgccatgacacctatggccaa
gctctggccaacacgttggtggccctgcagatgggagtgagcgttgtggactcctcggtg
gcaggactcggaggctgtccctatgcaaagggggcgtcaggaaacttggctaccgaggac
ctggtctacatgctgactggcttagggattcacacgggtgtgaacctccagaagctccta
gaagccggggacttcatctgtcaagccctgaacagaaaaaccagttccaaagtggcacag
gccacctgcaaactctga
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