Rattus norvegicus (rat): 79243
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Entry
79243 CDS
T01003
Symbol
Hsd17b2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00140
Steroid hormone biosynthesis
rno01100
Metabolic pathways
rno04913
Ovarian steroidogenesis
Module
rno_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
79243 (Hsd17b2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
79243 (Hsd17b2)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
79243 (Hsd17b2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
79243 (Hsd17b2)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
DUF1776
KR
Polysacc_synt_2
Epimerase
NmrA
Motif
Other DBs
NCBI-GeneID:
79243
NCBI-ProteinID:
NP_077367
RGD:
621803
Ensembl:
ENSRNOG00000013982
UniProt:
Q62730
F7EZ71
Q5I0N4
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All DBs
Position
19:62662320..62733944
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AA seq
381 aa
AA seq
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MNPFSSESAWLCLTATAVLGGMLLCKAWSSGQLRSQVVCLAGLWGGACLLSLSLLCSLFL
LSVSCFFLLYVSSSDQDLLPVDQKAVLVTGADSGFGHALAKHLDKLGFTVFAGVLDKEGP
GAEELRKNCSERLSVLQMDVTKPEQIKDVHSEVAEKIQDKGLWAVVNNAGVLHFPIDGEL
IPMTVYRKCMAVNFFGAVEVTKVFLPLLRKSKGRLVNVSSMGAMIPFQMMAAYASTKAAI
SMFSAVIRQELAKWGVKVVTIHPGGFQTNIVGSQDSWDKMEKEILDHFSKEIQENYGQEY
VHTQKLALPVMREMSNPDITPVLRDIQHAICAKNHSSFYCSGRMTYLWICFAAYSPISLL
DYILKNYFTPKLMPRALRTAS
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgaacccgttttcctctgagtcagcatggctctgcttgactgccactgcggtgctgggg
ggcatgcttctctgcaaagcctggagttcagggcagctaaggagccaggtggtgtgtctg
gctggcctctggggaggtgcctgcctgctcagcctgtccctcctctgcagcttgttcctc
ttatcggtgtcctgcttcttccttctgtatgtgagttcatctgaccaagacttgttacct
gtggatcaaaaggctgtgctggtgacaggtgccgattccggtttcggtcatgctttggcc
aagcacctggacaagctgggtttcacagtgtttgctggagtgctggataaagagggccca
ggagcggaggaattgaggaaaaactgctctgagcgcctttcggtgctccagatggatgtc
accaagccagagcagataaaagatgttcacagcgaagtcgcagagaagatacaagacaaa
ggactgtgggctgtggtcaacaatgctggggtcttgcactttccgatcgacggggaactc
attcccatgaccgtgtacagaaaatgcatggcagtgaacttcttcggagccgtcgaggtc
accaaggtgtttctgcctctacttagaaagtccaaggggaggctggttaacgtcagcagc
atgggagccatgattccatttcagatgatggccgcctacgcctccacgaaggcagctata
agcatgttctcagccgtcatcaggcaagagcttgccaaatggggagtcaaagtcgtgacc
atccatcctggaggcttccaaacaaacatcgtaggctcacaggacagttgggataaaatg
gagaaggagatcctggaccacttttccaaagagattcaggagaactatggacaggaatat
gtccatacgcagaagctcgccctcccggtcatgagagagatgtccaacccggatatcacc
cctgtgctgcgggacatccagcacgccatttgtgccaagaaccactcttccttttattgc
tcagggagaatgacttacctgtggatctgcttcgcggcctactccccgatcagcttattg
gactatattttgaaaaactattttactccaaaactcatgccaagagctttaaggacagca
agttag
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