Rattus norvegicus (rat): 81643
Help
Entry
81643 CDS
T01003
Symbol
Atic
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00230
Purine metabolism
rno00670
One carbon pool by folate
rno01100
Metabolic pathways
rno01523
Antifolate resistance
Module
rno_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
81643 (Atic)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
81643 (Atic)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
81643 (Atic)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
rno04147
]
81643 (Atic)
Enzymes [BR:
rno01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
81643 (Atic)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
81643 (Atic)
Exosome [BR:
rno04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
81643 (Atic)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-GeneID:
81643
NCBI-ProteinID:
NP_112276
RGD:
70879
Ensembl:
ENSRNOG00000015511
UniProt:
O35567
A6KFG3
LinkDB
All DBs
Position
9:80614311..80634360
Genome browser
AA seq
592 aa
AA seq
DB search
MASSQLALFSVSDKTGLVEFARNLASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDAADMARLDFNLIRVVVCNLYPFVKTVASPDVTVEAA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYGAVAAEMQGSGNKDTSLETRRHLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDLYPTLTPLA
IAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNG
SYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKA
GVKRAEVSNAIDQYVTGTIGEGEDLVKWKALFEEVPELLTEAEKKEWVDKLSGVSVSSDA
FFPFRDNVDRAKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcttcctcccagcttgccctgttcagtgtgtctgacaaaactggcctcgtggaattt
gccagaaacctcgcgtctcttggtttgagtttggtcgcttctggaggcacggcaaaagcg
atcagggatgctggcctggcagtgagagatgtgtctgagctaactgggttccctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaatcttagcacgcaat
attccagaagatgctgctgacatggccaggcttgatttcaacctcataagagttgttgtc
tgtaacctgtacccgttcgtgaagactgtggcttctccagatgtaaccgttgaggcagct
gttgagcaaattgacattggtggcgtgaccttactgagagctgcagccaaaaaccatgct
cgagtgacagttgtgtgtgagccagaggactatggtgcggtggctgcagagatgcagggc
tctggtaataaggacacctccctggagaccaggcgccacttggcattgaaggcattcacg
cataccgctcaatatgatgaagcgatttcggattacttcaggagacagtacagtaaagga
atttctcagatgcccttgaggtatgggatgaacccccatcagactcctgcccagctgtat
acactgaagcccaagcttcccatcacagttctcaacggagccccaggattcataaacctc
tgcgatgctttgaatgcctggcagctggtgacagagctgagaggagcagtagacattcca
gctgcggcgtctttcaagcacgtcagcccagcaggtgctgctgttggggttccactcagt
gaggacgaagccagagtctgcatggtctatgacctctatccgaccctcacgcccctggcc
attgcatatgcaagagcaagaggagctgataggatgtcttcatttggtgattttgttgca
ttatctgatgtttgtgatgtcccaactgcaaaaattatctccagagaagtgtcagatggt
attgttgccccaggatatgaggaagaggccttgaaaatactttctaaaaagaaaaatgga
agctactgtgttcttcagatggaccagtcctacaaaccggatgaaaatgaagttcgaacg
ctctttggtcttcgtttaagccagaagagaaataatggtgttgttgacaagtcgttgttt
agcaatattgtcaccaagaataaagatctgccggaatctgctctccgagacctcattgtc
gccaccatcgctgtcaagtatactcagtctaattcggtgtgctatgccaaggacgggcag
gttattggcatcggagcaggacagcagtctcggatacactgtacacgccttgcaggtgat
aaggcaaactcttggtggcttcggcaccatccacgagtgctttccatgaagtttaaagct
ggggtgaagagagcagaagtctccaatgccatcgatcagtatgtgaccggcaccattggt
gagggtgaagacctggtgaaatggaaagcactgtttgaagaggttcctgagttactcact
gaggcggagaagaaggaatgggtggacaagctgagtggcgtgtctgtcagttccgatgct
ttctttcctttcagggataatgtagaccgagcgaaaaggagtggtgtggcctacattgtt
gctccatccggatctactgctgacaaggttgtgatcgaggcgtgtgacgagctggggatc
gtgttggctcatacagatctgcgtctcttccaccactga
DBGET
integrated database retrieval system
