Rattus norvegicus (rat): 83805
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Entry
83805 CDS
T01003
Symbol
Src
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno01522
Endocrine resistance
rno04012
ErbB signaling pathway
rno04015
Rap1 signaling pathway
rno04062
Chemokine signaling pathway
rno04081
Hormone signaling
rno04137
Mitophagy - animal
rno04144
Endocytosis
rno04360
Axon guidance
rno04370
VEGF signaling pathway
rno04510
Focal adhesion
rno04520
Adherens junction
rno04530
Tight junction
rno04540
Gap junction
rno04611
Platelet activation
rno04613
Neutrophil extracellular trap formation
rno04625
C-type lectin receptor signaling pathway
rno04727
GABAergic synapse
rno04750
Inflammatory mediator regulation of TRP channels
rno04810
Regulation of actin cytoskeleton
rno04912
GnRH signaling pathway
rno04915
Estrogen signaling pathway
rno04917
Prolactin signaling pathway
rno04919
Thyroid hormone signaling pathway
rno04921
Oxytocin signaling pathway
rno04926
Relaxin signaling pathway
rno05100
Bacterial invasion of epithelial cells
rno05135
Yersinia infection
rno05152
Tuberculosis
rno05161
Hepatitis B
rno05163
Human cytomegalovirus infection
rno05167
Kaposi sarcoma-associated herpesvirus infection
rno05168
Herpes simplex virus 1 infection
rno05203
Viral carcinogenesis
rno05205
Proteoglycans in cancer
rno05207
Chemical carcinogenesis - receptor activation
rno05208
Chemical carcinogenesis - reactive oxygen species
rno05219
Bladder cancer
rno05417
Lipid and atherosclerosis
rno05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
83805 (Src)
04015 Rap1 signaling pathway
83805 (Src)
04370 VEGF signaling pathway
83805 (Src)
09133 Signaling molecules and interaction
04081 Hormone signaling
83805 (Src)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
83805 (Src)
04137 Mitophagy - animal
83805 (Src)
09144 Cellular community - eukaryotes
04510 Focal adhesion
83805 (Src)
04520 Adherens junction
83805 (Src)
04530 Tight junction
83805 (Src)
04540 Gap junction
83805 (Src)
09142 Cell motility
04810 Regulation of actin cytoskeleton
83805 (Src)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
83805 (Src)
04613 Neutrophil extracellular trap formation
83805 (Src)
04625 C-type lectin receptor signaling pathway
83805 (Src)
04062 Chemokine signaling pathway
83805 (Src)
09152 Endocrine system
04912 GnRH signaling pathway
83805 (Src)
04915 Estrogen signaling pathway
83805 (Src)
04917 Prolactin signaling pathway
83805 (Src)
04921 Oxytocin signaling pathway
83805 (Src)
04926 Relaxin signaling pathway
83805 (Src)
04919 Thyroid hormone signaling pathway
83805 (Src)
09156 Nervous system
04727 GABAergic synapse
83805 (Src)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
83805 (Src)
09158 Development and regeneration
04360 Axon guidance
83805 (Src)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
83805 (Src)
05207 Chemical carcinogenesis - receptor activation
83805 (Src)
05208 Chemical carcinogenesis - reactive oxygen species
83805 (Src)
05203 Viral carcinogenesis
83805 (Src)
09162 Cancer: specific types
05219 Bladder cancer
83805 (Src)
09172 Infectious disease: viral
05161 Hepatitis B
83805 (Src)
05168 Herpes simplex virus 1 infection
83805 (Src)
05163 Human cytomegalovirus infection
83805 (Src)
05167 Kaposi sarcoma-associated herpesvirus infection
83805 (Src)
09171 Infectious disease: bacterial
05135 Yersinia infection
83805 (Src)
05152 Tuberculosis
83805 (Src)
05100 Bacterial invasion of epithelial cells
83805 (Src)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
83805 (Src)
05418 Fluid shear stress and atherosclerosis
83805 (Src)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
83805 (Src)
01522 Endocrine resistance
83805 (Src)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
83805 (Src)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
83805 (Src)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
83805 (Src)
Protein kinases [BR:
rno01001
]
Non-receptor tyrosine kinases
SRC family
83805 (Src)
Membrane trafficking [BR:
rno04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
83805 (Src)
Endocytosis
Clathrin-mediated endocytosis
Kinases
83805 (Src)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
83805 (Src)
Macropinocytosis
Kinases
83805 (Src)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH2_1
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
83805
NCBI-ProteinID:
NP_114183
RGD:
620795
Ensembl:
ENSRNOG00000009495
UniProt:
Q9WUD9
LinkDB
All DBs
Position
3:166511616..166559463
Genome browser
AA seq
542 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENVHGAGGAFPASQTPSKPASADGHRGPNAAFVPPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLK
GETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq
1629 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggacgccagccagaggcgccgcagcctggagccc
gcggagaacgtgcatggggcaggtggcgccttccctgcctcacagacaccaagcaagcct
gcctccgccgatggccaccgcgggcccaatgccgcctttgtgccccccgcggccgccgag
cccaagctcttcggaggcttcaactcctcggacactgtcacctccccacaaagggcgggg
cctctggcaggtggggtgactacctttgtggccctctatgactatgagtcacggacagag
actgacctgtccttcaagaaaggggagcggctgcagattgtcaataacacgaggaaggtg
gatgtcagagagggagactggtggctggcacactcgctgagcaccggacagaccggttac
atccccagtaactatgtggcgccctccgactccatccaggctgaggagtggtactttggc
aagatcactagacgggaatcagagcggctacttctcaacgccgagaaccccagagggacc
ttcctcgtgagggagagtgagaccacaaaaggtgcctactgcctctctgtatccgacttt
gacaatgccaagggcctaaatgtgaaacactacaagatccggaaactggacagtggcgga
ttctacatcacctcccgcacgcaattcaacagcctgcagcagcttgtggcttactactcc
aaacatgctgatggcctgtgtcaccgtctcactaccgtgtgtcccacatccaagcctcag
acccagggcctggccaaggatgcgtgggagatcccccgggagtccctgcggctggaggtc
aagctgggccagggttgcttcggagaggtgtggatggggacctggaacggcaccacgagg
gttgccatcaaaaccctgaagccaggcaccatgtctccagaggccttcctgcaggaggcc
caagtcatgaagaaactgaggcatgagaagctggtgcagctgtatgccgtggtgtcagaa
gaacccatttacattgtgacagagtacatgaacaaggggagtctgctggactttctcaag
ggggaaacgggcaaatacttgcggctaccccagctggtggacatgtctgctcagattgct
tcaggcatggcctatgtggagcggatgaactatgtgcaccgggacctccgagccgccaat
atcctggttggcgagaacctggtgtgcaaagtggccgactttgggctggcccggctcata
gaggacaacgaatacacagctcggcaaggtgccaaattccccatcaagtggaccgcccct
gaagcggctctgtatggcaggttcaccatcaagtcggacgtgtggtcctttggaatcctg
ctgactgagctcaccactaagggcagagtgccctatcctgggatggtgaaccgagaggtg
ctggaccaggtagagcggggctaccggatgccttgtccccccgagtgccctgagtccctg
catgacctcatgtgccagtgctggcggaaggagcctgaggagcggcccaccttcgagtac
ctgcaggccttcctggaggactactttacgtccacggagccgcagtaccagcccggggag
aacctatag
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