Roseovarius sp. AK1035: RAK1035_2485
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Entry
RAK1035_2485 CDS
T05517
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rok
Roseovarius sp. AK1035
Pathway
rok00300
Lysine biosynthesis
rok00550
Peptidoglycan biosynthesis
rok01100
Metabolic pathways
rok01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rok00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RAK1035_2485
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RAK1035_2485
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RAK1035_2485
Enzymes [BR:
rok01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RAK1035_2485
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AWZ21193
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Position
2559544..2560980
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AA seq
478 aa
AA seq
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MSLWSAKEAVAATQGRSTADWQATGVSIDTRTLKPGDLFVALNAARDGHEFVAQALAKGA
AAALVSRIPEGLPAEAPLLIVEDVQKGLEDLGRAARARSEARVVAVTGSVGKTSTKEMLR
DVLGHQGRTHAAEASYNNHWGVPLTLARMPVDTEFAVIEIGMNHPGEIAPLACMARPHVA
VITTVAAAHLEAFENIDGIAKEKASIFEGLEPGGVAVINADIATTPILRAKAAQHAARIL
SFGTARGAHHRLLNVELHDHVTVGHARAWRSPLVYKVGVPGRHFAMNALAVLAVAQVLGC
DRAVAMADLASWAPPAGRGTREELVLDLASDGMSIDLIDDAFNANPTSMAAALEVLAAAH
PRDGVGRVSRGRRIAILGDMLELGPDEAAMHAGLADLPYMARINEIHCVGPRMRALWDIL
PEARRGRWVASAEELAAQAHRLIDAGDVVLVKGSKGSRVSLVVEALRRVGRVTEEGQV
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atgagcctttggtcagcaaaagaagcggtagccgcgacgcaggggcgtagcacagccgac
tggcaggcgaccggcgtatccattgatacccgcaccctcaaacccggcgatctcttcgtg
gcgctcaacgcggcccgcgacgggcatgaatttgtggcgcaggcgctggccaagggggct
gcggcggcgctggtgtcgcgcatccccgaaggcctgcccgccgaggccccgctgttgatt
gttgaggatgtgcaaaaggggcttgaggatctgggccgtgcggcgcgtgcccgctcggag
gcccgcgttgtggccgtgacgggatcggttggcaaaacctcgaccaaggaaatgctgcgc
gatgtgttgggccatcaaggccgcacccatgccgccgaggccagttacaacaatcactgg
ggcgtgccgcttacgctggcgcggatgccggtggatacagagtttgccgtgatcgaaatc
ggcatgaaccaccccggtgagattgcccctctggcgtgtatggcgcggccgcatgtggcg
gtgatcaccaccgtcgccgctgcacatcttgaagcgttcgagaatatcgacggcatcgcc
aaagaaaaggccagcatttttgaagggttagagccggggggcgtggcggtgatcaacgcc
gacatcgcgaccacgcccattttgcgcgccaaggctgcgcagcatgcggcgcgcatcctc
agctttggcaccgcgcgcggtgcgcatcaccgcctgctcaacgtcgaactgcatgaccac
gtgaccgtgggccacgcccgcgcatggcgctcgccgctggtttacaaggtgggcgtgccg
gggcggcattttgcaatgaacgcgctggccgttttggcggtggcgcaggtgctgggctgt
gaccgggccgtggccatggctgatctggccagttgggccccccccgccgggcgcggcacc
cgcgaagagctggtgcttgatctggccagcgacgggatgagcattgacctgatcgacgat
gcgttcaacgccaatccgacctctatggccgccgcgctcgaagtgctggcggcggcgcac
ccgcgggatggtgtgggccgcgtgtcgcgcgggcgcaggatcgccattctgggcgacatg
ctggaacttgggccggatgaggccgcaatgcacgcaggattggctgatctgccctatatg
gcgcggataaacgaaatccactgcgttggtccccgtatgcgcgccctgtgggatattctg
ccagaggcgcggcgcggtcgttgggtggccagcgccgaagagctggcagcgcaggcgcac
cggctgatcgacgcaggcgatgtggtattggtaaagggttccaagggcagccgggtgagc
cttgtggtcgaggcgctgcggcgcgtgggccgggtgacagaagaaggacaagtctaa
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