Rhodococcus opacus B4: ROP_17230
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Entry
ROP_17230 CDS
T00882
Symbol
cysGA_hemD
Name
(GenBank) putative uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rop
Rhodococcus opacus B4
Pathway
rop00860
Porphyrin metabolism
rop01100
Metabolic pathways
rop01110
Biosynthesis of secondary metabolites
rop01120
Microbial metabolism in diverse environments
rop01240
Biosynthesis of cofactors
Module
rop_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
rop_M00925
Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
rop_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
rop00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ROP_17230 (cysGA_hemD)
Enzymes [BR:
rop01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
ROP_17230 (cysGA_hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
ROP_17230 (cysGA_hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BAH49970
UniProt:
C1AZ42
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All DBs
Position
complement(1828720..1830285)
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AA seq
521 aa
AA seq
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MSRVRKNTPGRILFVGSGPGDPALLTVHARDVLAAATLAFTDPDVDKGVTVLVGTDLGVD
AETGEPLAEVRPALGEPAEVAKTLVHEAKNGHDVVRLVSGDPLTTDSVIAEVTAVARTQV
QFEVLPGLPSASAVPSYAGMALGSGHTEADVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVEHGLAPQTPAAITVRGTTRQQRTVEATLATLNEAGSELVGSLVVTVGKVVAQRNKM
SWWESRALYGWKVLVPRTKDQAGEMSDRLVTHGAIPIEVPTIAVEPPRSPAQMERSVKGL
VDGRYQWVVFTSTNAVRAVWEKFEEFGLDARAFSGVKIACIGEATAAKVRSFGINPELVP
SGEQSSEGLLAEFAPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAETREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPKTAETAIEFGLR
VDVQPETAQVGPLVEALAEHAARLRAEGALPPPRKKSRARR
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagtccgtaagaacacccccggacgaatcctgttcgtgggatccggaccgggc
gatccggcactgctcaccgtgcacgcacgggacgtccttgccgcagccaccctcgccttc
accgaccccgacgtcgacaagggcgtcaccgtcctggtgggcaccgacctgggcgtcgac
gccgagaccggtgagccgctcgccgaggtccgtcccgcactgggcgagccggcggaggtc
gcgaagaccctcgtccacgaggcgaagaacggccacgacgtcgtgcgcctggtgtccggc
gacccgctgaccaccgactccgtgatcgccgaggtcaccgccgtcgcccgcacccaggtg
cagttcgaggtcctgccgggactgccgtccgcgtccgccgttccgtcctacgccggtatg
gcactggggtcgggacacaccgaggccgacgtccgcggcgaggtcgactgggcggccctg
gccgccgcacccggaccactggtcctgcacgccacgtcgggtcatctcgccgagacggcg
agcgccctcgtcgagcacggcctggccccgcagaccccggcggccatcacggtccgcggc
acgacccggcagcagcgcaccgtcgaggccaccctcgcgacgctgaacgaggccggttcc
gaactggtcggttcgctggtcgtgacggtcggcaaggtcgtcgcccagcgcaacaagatg
tcctggtgggagtcgcgcgcgctgtacggctggaaggtcctggtgccgcgcaccaaggat
caggcgggcgagatgagcgaccgcctcgtcacgcacggcgccatcccgatcgaggtgccc
accatcgccgtcgagccgccccgcagcccggcgcagatggaacggtccgtgaagggcctc
gtcgacggccgctaccagtgggtggtcttcacctccaccaacgcggtgcgtgcggtgtgg
gagaagttcgaggagttcggactcgacgcccgtgcattctccggcgtcaagatcgcctgc
atcggtgaggccaccgcggccaaggtgcgctcgttcgggatcaaccccgaactcgtgccg
tccggtgagcagtcgagtgaaggcctgctggccgaattcgccccgtacgacgacgttttc
gaccccgtcaaccgggttctgctgccccgcgccgacatcgccaccgagacgctcgccgag
ggcctgcgcgaacgcggctgggaaatcgacgacgtcaccgcgtaccgcaccgtgcgggcc
gcgccgccgccggccgagacccgcgagatgatcaagaccggtgggttcgacgccgtctgc
ttcacctcgtcctcgacggtccgcaacctcgtcggcatcgccggaaagccgcacgcgcgc
accctcgtcgcctgcatcggcccgaagaccgccgagactgccatcgagttcggcctgcgg
gtggacgtgcagccggagaccgctcaggtcgggccgctggtggaggctctcgcagagcac
gccgcgcggctgcgcgcggagggcgcactgcccccgccgcgcaagaagtcccgcgcacgg
cgatag
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