Roseovarius phycicola: RZ517_12460
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Entry
RZ517_12460 CDS
T10600
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rphc Roseovarius phycicola
Pathway
rphc00300
Lysine biosynthesis
rphc00550
Peptidoglycan biosynthesis
rphc01100
Metabolic pathways
rphc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rphc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RZ517_12460 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RZ517_12460 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RZ517_12460 (murF)
Enzymes [BR:
rphc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RZ517_12460 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WWR45600
LinkDB
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Position
complement(2453433..2454875)
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AA seq
480 aa
AA seq
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MSLWTAAEAAAATGGENTQDWSASGVSIDTRTLKPGDLFVALRDVRDGHDFVAQALAKGA
AAALVSHVPKDVDPEAPLLVVKDVLPALEALGQAARARTEARVVAVTGSVGKTSTKDMLR
TVLAGQGRTHAAEASYNNHWGVPLTLARMPVDTEFAVIEIGMNHPGEIAPLSRMARPHVA
IVTTVAPAHLEAFENIEGIAHEKASIFEGLEPNGTAIVNGDVDTAAILRETAERLAGTVV
SFGESEGLNWQLRDVQVHNTSTVAKAQVSGEHVLFKVGTPGAHFAANALAVLAAVDAMGA
DLDVAVSDLGRWHPPSGRGTHETLLLDVADETLTIALIDDAFNANPASMEASLAVLAGTV
PEDDIGRVAAGRRIAVLGDMLELGPDEAVLHADLANLPAMQELDIVHCVGSRMRALYDAL
PERKRGRWVNEAEELAAQAARLIDAGDVILVKGSKGSRVSRVVEALRRAARGGTREEEDV
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgagtctctggaccgcagccgaggccgcagcggccacaggcggggaaaacacgcaggat
tggtcggcctcgggtgtttcgattgatacgcgcacgctgaagcccggcgatttgttcgtg
gcgctcagggatgtgcgcgacgggcatgattttgttgcacaagcgcttgccaagggcgcg
gcagcggcgctggtcagccatgtgcctaaggatgtggaccccgaggcgccgcttctggtg
gtgaaagatgttttacctgcgctggaggctttggggcaggccgcgcgtgcaaggacagaa
gcgcgtgttgttgccgtgaccggatcggtgggcaagacttcgaccaaggacatgctgcgc
acggtgctggccggacaggggcggacgcatgcggcagaggccagttacaacaaccattgg
ggtgttccgctgacgttggcgcggatgcccgtagacaccgaattcgccgtcatcgagatc
ggcatgaaccatcccggagagatcgcacctctatcacgcatggcgcgtccacatgtggcg
atcgtcaccaccgtggcacctgcgcatcttgaggcgttcgagaatatcgaaggcatcgcg
catgaaaaggcgtcaatctttgaagggctagagccgaacggcacggcgattgtgaatggt
gatgtggacacagcggcaatcctgcgcgagaccgcagagcgcctggccgggaccgtggtg
tcctttggcgaaagtgaaggtctcaattggcaattgagggacgtacaggtccacaacacc
tctactgtggccaaggcgcaggtttcaggtgaacatgtactcttcaaggtcggcacaccc
ggagcgcacttcgccgccaacgcgctcgccgttctggccgccgtggatgccatgggcgca
gacctcgatgttgcggtgtcggatctgggtcgctggcatccgccttcggggcgcggcacg
catgagacgcttttgctggatgtggccgatgagacgctgaccatcgcgcttattgacgat
gcgtttaacgccaaccccgcctcaatggaggcgtcgctggcggttttggcgggaacggtt
cccgaggacgacatcgggcgtgtcgccgcgggtcgccgtatcgcggttttgggggatatg
ttggaactaggccctgatgaggcagtgcttcatgccgatctggccaatcttccagccatg
caagagcttgacattgtccattgtgtcgggtcacggatgcgcgcgctttacgatgcgctg
ccagagcgtaagcggggacgctgggtgaacgaagccgaagagcttgcagcccaggcggcc
cgcttgattgatgcaggtgacgtgatcctggtcaaaggctccaaaggcagccgggtgagc
cgcgtggttgaggcgctcagacgtgcagcgcgcggtgggacgcgtgaagaagaggatgtg
tag
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