Ruditapes philippinarum (Manila clam): 132751936 Help Entry 132751936         CDS       T09557                                  Name (RefSeq) polycystin-1-like isoform X1   KO K04985   polycystin 1 Organism rphi  Ruditapes philippinarum (Manila clam) Brite KEGG Orthology (KO) [BR:rphi00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:rphi03037]     132751936    04812 Cytoskeleton proteins [BR:rphi04812]     132751936    04040 Ion channels [BR:rphi04040]     132751936    04091 Lectins [BR:rphi04091]     132751936 Cilium and associated proteins [BR:rphi03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    132751936 Cytoskeleton proteins [BR:rphi04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     132751936 Ion channels [BR:rphi04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    132751936 Lectins [BR:rphi04091]  C-Type lectins   Others    132751936 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PKD REJ LRR_8 Polycystin_dom PKD_4 PKD_channel PLAT Lectin_C LRR_4 EB GPS PKD_3 LRR_9 LED_rpt Motif Other DBs NCBI-GeneID:  132751936 NCBI-ProteinID:  XP_060598138 LinkDB All DBs Position Unknown AA seq 5144 aa AA seqDB search MPRKSPLFCPLSMKNNSQSARNHHGVSHSWRFTLFVLGLLLCFFAPDYVEAVFTPPAGCT SSTWIYQNNKVQNISCRGQNLLSVPTDAKEGSDVIRLDLADNLISNLSNNEFQYFTNLLD LDLSNNKISVFDLDTFTNLTNLQFLNLAGNNLSTLPSGTFTSISVTTLDLSSINLQSVDR DHFKNLVNLEELYLSHNNLSILEQHLFKDLQSLRLIDLSHNVITYVDKDFLNDANSLTNL DLSNNRIASLDKSTFNDLKYLEILYLNDNLLTSLDTDIFKELTSLTTLHLTTNLLTTLNR DVFKELDSLTSLYLGNNAQTTVHKDLFQHNSNLQDLSLSANQLSTIPTDIFDHQTTFQVD LSGNPFICSCDIRDFLFSLKYSTSISLIDEGAILCTDASLQQHINLDYDNANCSGNLGAA CTVTYDCKVRNAQCSNSKCICPANFYDTNLNTTNGGLCYAKVDLDHECPGMDTACMGSHV ECAVKSPSSANTYCLCESAYYDDNPQYVGGTCRLKVELGQPCTSINNMCRPDYSLCGTSD TCECQTGYYDNDGTLNIGGDCLQVLALYSSCNQSYQCGPANSECTNSACSCMPGYYDFTN IGQCKADNGRHKRDSHVLKTYCKNHGIALHNCRPSGFYSCYPDNTSSVEVVFDKVNIVST EEECKNYCFVENVRYYLVEGSNICICGNTTTSKSCCPKISDQCSSRSYLGPITTLAEAGI RMSHIPRLVEGKSHEVSVTTSLTAIDQINLRFGDSQTIKTVNASSVTTQHTYTHSGLFWL TVSACAATRNVCEDASLPIRVQVPAVNLTTYMTAITLADVSSNLSSSFSATFSMGYDIDY RWSKTYGGTVTKRKSCKPGWTQHRNKCIKLMTSPTSYSTAKTTCAADGSLLKISFMQELT EIVTALSASSETLLIGAERAGGVWQWSDGSKTVFFDDDLVSSTNGDCVALVGSSSTLTSI SCTTSTKYVCMSDPVDCPKGGDLLSNDYCYVLASTESVSAKNWNAANQYCASYFGGWLTN VTDAAVQSKVTSLLTSHSVSEAWIGLSDQQVEGSYLWGDFSSFDFNSASYLPTVTSNSGD CFVATSANTWNSQDCTNIRDFVCQYSERIERLTVPSFVSGTADLDITPGQDIQQAVAAST FPSAATSSLEILIFPGLPFARSGTIRQVNFRSVNVVSGNYDVSFQIYRPSCTTGYLYQAG CVPTMFSSCVAGTYSCTPNTGCSDSEYFCLLSNSCVFKNESCTCNSVSVPTTTSGCGSPG SVSNYELITQLSVTFSNTGERWYGVTGELAVQEGDIIGLQYPTGKNIVNCENRPSSLDQQ KVMKGTTSNWLVKKDSFPATATTEDLTCDMQFVYTQDLAKNLPNNLGYMDTVGNYQLAIS IIETETKTVSISLEESVADVELVYPVLGLTNTSLTSLGAVYTEWNVAYHFTIAAGRGTNL SLKCALLTGQTFTFTSSCHSSVSSEVGDNCNSSMWWSDTPFATFTYNTSAVGTISTTIEV SNSLSAQSYTLYIITEKRITGVVFSLKTPSRLPNCIRKGTTAQFDLENTEGTNPSYSFKV AGVSAASRNASLFYSFPTIGTFTVAGTISNNLDSQTKSINVSVKQEASFTNCKLLDTPYI AAVGISFDLKLQCECSIGSEVNTHWMFSDSTANITTADVTVSSSPKSWTQAVTFSSVSTV DLAVYAMDAFQAVLVNGSVNVYNAIPTITVTANSSNVFLNTVVEITVNVPTSPGNYYNIN YSYDFGDGSTKTSASSVVTHSFTTGNNYTVSVTASNGPSSQTASMNIVVYEAVTVTALTN DGPKQTGNPITFTASVSSGNFLSYRYVSSNSAFDVTRSTGTYTHTFASAGNYSVTVTVSN MLSTQSVSTQAYVMNAGDLIISGFKIDGNDVSGCYESTIGRSYKVDLIHYSVATIVCDWN FGDGQTYTGTTCHKTHAFTTASNFTITVTAKYHLHSATETLSQQVCIQERITTPTMSIES TVTLPSSGSVKRNVTVAVATGSPLTYAWLTNATGTTSTDAILPVEFTSEGTYYFTVTVSN NVNSETVTKSVTVIEELSGVTIVCSSCLEISGEYYIQNNVATEFKVTTTTGSGSFAWDFG DSTTGTGISNFHTYTSIDTYNVTVTASSMVTTAVTQYITVHVEAAITSVTMQNRLYDWLT NKRDSSVKDLNILNTGRFDATVTPAGMDLDYIWKCESGTIEETTQVNEWDHKFPTKGSKS CTVTVKNSLGNMTSSAFTFFVVEKLLGSSLQVTENGNALTGTNETHTYKAKLNEVITFTV TSSQIVPNTVEYFLRLKKKSTGSSIYALQNSTIDKDDPTLSYRLDENALYQLEAIVTNSL GPVSITVYVEVVEAVSGPYINPAPGKDGNITLGSSITLTGGATNGEYKEFNWLYASAPSG QVLPTTTTSDIVITPSVVGLYIVTLEVSNAVSGPISVNYTINVMIGVSGVQISVTMPYTN AVRVYTSLTFTAQIAAGTSPSYSWNALVSGTTNSTGTAQTFVYQFMSQALYNITLFAENY ASSGTAYKEIYSLYDVPTFTLSMSGASYITSISKHAAPSNTIITFSSSITNTEYMQFNWN IGGTSVAATETLQKNFTSAAEYTVQLTASNLISNENSQISILVQDSISDFDVQNCIGTYM MNTVITLTSSYKGTDISVDWTRQGLASVTSAATTVQYSTVGIYSVNVTGRNYVSQETKNC WISIQGPIGNLNLQASVYKYVGYPITFNVSGDYINPAIFTWVFSHGVNMTTSNSPTLDLS FTTSGNYTLTVIVANDVSSSRKSISFQVKDLGCSAPTVTVVGSTDKRSPRAREVEISVDV STGGCSSYSSSNSWKVYSASSCVASLQNEYTLPSTIKTDLPSIVLLSNTLNYGTYCVVFQ HTYENTPVEAFKYFNLTIVPSDLVSVLSGGHKVGVRVASTLSLDASQSYDPDNVPATTLN FAWSCTQTMGSSAAAAVCNGISAITNASTILTGLTLTVNDVYVVTVTVSATGRIASSFTQ TITILSNTAPVISINCVSCQANGHYFLTRSRSVSFEGACIGCNTASLQWTVKENSTGTAD TIDSTKTTTDTNQMNFVLLSGVIQDNKAYVFKLEATVGSETGQAEIVLAPSSKPSGGICT LSPSAGVVALTDTATYSCSNVVDSDSLSAIYYKVTVRSTTSYKTPYIAYYGSKSVNSIFV VPFPGTNYSSVQIEISAVNFYRAETVLYTRTVSFVAPTLSSSQAHKTDYIVDQMLSNMKT IVRQNNPPLLLQYCMSVLSYLNDQSENNVGTLAQRMAIRDVIMNSLSGLPLTSIYNIQQM ATAIEYLVEHTEEVSLATLSSALSEIEAMTELLESTVSRGDDQRDYDSNTLIKANANMQQ ALKSLSTVTSDSATLAKFGSLSDYVLQVSSSVQTTSYSSDEAQTQALIIKSMKSSTQLLI LPLLAQVADENPIQKVTTDYEVMARHVSTDKITQNHNSNLGTSIQFPSDILTSRYTEPSV FQIVYISKIIQYNFGFSNLLPKNTLSLTTSFYKPSGDSVTVDNLSSGNEVIMYMFKNNVT SYPINDTAFHYSSGYDPLLHMNYSSRTLSPDASFAVNVNMPTEAGVGIHIQLRGNFTRAS AKLFATLYKNDIKFSETDSNTNKRPKTIDKAMMDDLKHDHTAYTFFISPSDYSTDDAFKV HLRVSESTQVLVGVYLTRCEFFNEGNEEWDNEGCLPHQDSIATCIKCACNHMTSFGGSLF VSPDELDFTDLSEVDFASNPVAIITCSVILGLYIILVVAFRKLDLMDLKRISLIPLCGKD GSFKYEVTIVTGRLPGAGTTAHVGIRLVGEYGKSARQHVIKSGAFKRNCSDTFIIAYDVN LGELKKIQIWHDNRGSSPSWYLSHVIVNDLQTDHKFYFFGNTWFSLEQENGTIQKELKVA GSNDMSKFSYRLKTAMFNSLADKHLWLSLFNRPAQSRFTRVQRVTCCVTILFTFVVVNAM WYGLLKKDNTELGLEGFGWEEVVLAMVSNIMVLPISIGLVYLFKKSRSKPNFFDHVHKPQ TAQTLEIENLCGNSQSGSFESTNTGAIPYDLERESTIDSVPHTAAGLHRSRHVAKSQREN TDDSIIQKRPSVAVTKASSKSPLWNEDNIMKWPESVNYDDGADSRPSTASTMAAGPSVRQ PPGKAGGSTPGASRKSKTLKKGDAGQLLDELDKLEHDLKESESRSVKSSGSKKSSTTLRR PTMHKSQWGSLEDILHSDDESVAESSAKMRKRGSTTSQSTIGKFNPRADPRISGNGGMWP ESRESVMSRESGGRSGRGITSGLRPGYYSEMTMESRDIPVHKEKCSLPPWCIYIAYTLCT LLVIFSSIIVILYCFRFGYQESVKWVLALILSLVLSFLIIEPLKALLIAVYVVATFKKVE EDEDEDFIDIEPTFDNSNEKIKDVKFKPISGFALLQAKEEGRKIHRMNVMIRQFIAYVFY LWLIMVLVYVNFQYDTYLMTKHVENDFIAPTTNDHLNFTNITTIDEFWEWTETVFIDSLY KENNTQDEEHAFLLGEARMRLIRGVTAKCEAANAASNLGASSLTDRTCYGQGNYDEDTDD YAEGWNDSNSNYSWRHYSAGELGSTHKIGHVATYGGGGYPQGLGTTSAETDSIIAHLKDK GWIDLQTRAVIFEFALYSAGSDITSMVALLAEFPLTGGVITSYEIQSQKLLWFQKDTVEP LMVLECILFLVIIYSVIHLALQIREWGKQFFKDIWNWYEMLTTLMALVSVGMYIGCVVEA TNTFNRFLDNQTGFTNYERAMYVHVGMRYLNAWLLFLLMFKVVKQMRFIKFMYVYERTLS SAVSHLLGTGLIYIILLLVYAQVGYLMYGRFVSGFESVGHSITTLIVMIRGSFDFWPMLD YQPVFSHFYVYSYYTFAYGIMIALVISILTSTYKVIKSQMYYKATLEMQDYEMVDFMLKR FKLLTGLQKPKPAFRRVRFPGLPSVSSRSSSSYSNRSAEPLPSEESVTGPQYSEVKLRSM MARLGPTWQAVLRRMDKIVALDDEEESLVKKADDEMKNLNWKCRINEIERQHKELLSWQN QPSTSDKPPLGDSKLRQSILKRPGASKDNQDRKAPATVSGAQIRTAASTPADDGNGAQGR RPLSDQGVRVEPASTSKRRASSNDKSKLQTFFRSIKPSKSAWNK NT seq 15435 nt NT seq  +upstreamnt  +downstreamnt atgccgcgaaaaagtcctctgttttgcccacttagtatgaagaacaattcacaaagtgca agaaaccatcatggggtgtcacattcttggagatttacactttttgtgctcggattatta ttatgttttttcgctccggactatgtggaagcggtgtttacaccgcctgccggttgcacc agctcaacatggatttaccaaaacaacaaagtgcagaacatctcctgtaggggtcagaac ctactatcagtgccaacagacgccaaagaaggcagcgatgttattaggcttgatcttgca gacaacctaatttcaaacctgtcaaacaatgaatttcagtattttaccaacttattagat ttagatttatcgaataacaagatttctgtttttgatcttgacactttcaccaacttgacg aacctccagtttttgaacttggcggggaacaatcttagtactttaccctcaggaactttc acatccatctctgttacaacattagatcttagctccataaatctacaaagtgttgacaga gatcatttcaaaaatcttgtaaaccttgaagaactttacctgtcacacaacaatttgagt atattggagcagcatttgtttaaagatctccagtctctaagactgatagatctaagtcac aatgttattacatatgtggacaaggactttctgaatgatgcgaattccttgaccaatctg gatctgagtaacaacagaatagcttccttagacaaatcaactttcaatgaccttaaatat ctagaaatattgtatttgaatgacaatttgttgacatcattggatacagatatattcaag gaacttacatcactaacaacattacatttaactacaaatctgctgactacactaaacagg gatgtgtttaaggaattggattcactcacttctttatatctaggcaacaatgcacaaaca acagttcacaaagatttgtttcaacacaattcaaatttgcaagacctgtctcttagtgcc aaccaattatcaacaattccaacagatatttttgatcatcagacaacatttcaagtggat ttgtcagggaatcctttcatatgtagctgtgatattcgggacttcctgttttctctaaaa tattccacaagtatctcactgatagatgaaggtgctattctatgtaccgatgcttcctta caacagcatatcaacttagactatgataacgccaactgctctggaaatcttggtgcagcc tgcacagttacttacgattgtaaagtgcgtaacgcacagtgtagtaactcaaaatgtatc tgtccggccaatttctacgacacaaatttaaatacaacaaacggtggactatgttatgca aaggtagatttagatcatgagtgtcccgggatggataccgcatgtatgggctctcatgta gaatgtgccgtcaaaagtccgtcttctgccaacacatattgtctgtgtgaatctgcatat tatgatgataatccgcagtatgtgggcggtacatgtaggctcaaggttgaactaggacag ccatgtacaagtataaacaacatgtgtcggccagattactcattgtgcggaacaagtgac acttgtgagtgtcagactggttactatgacaacgatggtacattaaacattggtggagat tgtcttcaagtacttgccctgtactctagttgtaaccagagttaccagtgcggccctgcc aactccgagtgtacaaacagtgcttgttcatgcatgcctggttactatgatttcaccaat ataggtcaatgcaaagctgataatggccgccacaaaagggattctcatgtgttgaaaact tactgtaaaaatcacggtatcgcactgcataattgtcgaccaagtggattttactcatgt tatccggataacacctccagtgtggaagttgtgtttgacaaagtaaacattgttagcacg gaggaagaatgcaagaattactgttttgtggagaatgtgagatattaccttgtagaagga tcaaacatttgtatttgcgggaatacaactacatccaagtcatgctgtccaaaaataagc gatcaatgttcatcaaggtcatatcttgggccgataacaacacttgctgaagcaggcatc agaatgtcccatattccgcgccttgttgaaggaaaatctcacgaagtatcggtaacaact tccttaacagcaatcgatcagatcaatttaaggtttggtgactcccagacaataaaaaca gtgaatgcatcaagtgttaccacccagcatacatacacacattccggcttgttctggtta acggtcagtgcgtgtgccgcgactagaaacgtttgtgaggatgcttcgttacctattcgt gtacaagtaccagcagtaaatctcacaacctatatgacagccattacactggcagatgtc tccagcaacttgagtagcagttttagcgcaactttctccatgggttatgatatagattac aggtggtcaaagacatatggtggcacagttacaaaacggaagagttgtaagccaggctgg acacaacacagaaacaagtgtatcaaactcatgacctctccaacatcatacagtactgca aagacaacatgtgctgcagacggctcacttttgaagatcagctttatgcaggaattaaca gagattgttactgcactcagtgcaagttcagaaactctgttaattggtgctgagagagca ggtggagtatggcaatggtcagatggctctaaaactgttttctttgatgatgatctggtc agctcaacaaacggagattgtgtcgcgttagtcggaagttctagtacactgaccagcatt tcctgcactacgtcaaccaaatatgtctgtatgtcagatcctgtagattgtcctaaaggt ggagatctattgagtaatgactattgttatgtacttgctagtacagaatcagtctccgct aaaaattggaacgctgctaatcaatattgcgcaagttattttggcggctggttgactaat gtcacagacgcagccgtgcaatccaaagtgacatctctgctcacaagccacagtgtgagt gaggcttggattggattgtcagatcaacaggtagagggttcgtatctctggggagatttt tcatcatttgatttcaattctgcctcgtacctgccaacggtgacctcaaatagtggtgac tgttttgttgcaacaagtgctaacacctggaactcccaggactgtactaacatccgggac tttgtgtgtcagtattcagaacgaattgagagattaacagtgccaagcttcgtatccggg actgcagaccttgatataactcccggccaggatatacaacaagctgtagctgccagcacc ttcccatctgctgctacttcctctctggaaattctcatctttccaggcctaccttttgca agatctggaactatcaggcaggtgaatttccggtcagttaatgtggtgtcaggaaactat gatgtttctttccaaatataccgaccatcgtgcaccaccggatatctttaccaagcaggc tgtgtgcctaccatgttctcaagttgtgttgctggaacttactcatgtacgccgaacaca ggctgttcagactcggaatatttctgtctactcagcaactcttgtgtattcaagaatgaa tcatgcacatgtaattctgtatcagtaccaacaacaacttctggctgtggtagcccaggt agtgtatcaaactatgaacttataactcagttgtcggtgacattttccaacaccggtgaa agatggtacggtgtgaccggagaactagctgttcaggaaggtgacattattggtttacag tatcctactgggaaaaatattgtcaattgtgagaatcgtccatcaagcttagatcagcag aaggttatgaaagggactacaagtaactggcttgtgaaaaaggactcttttccagccacc gccacaactgaagatttgacatgtgacatgcagtttgtttatacccaggatttagcgaag aatttaccaaacaatctagggtacatggatacagtgggcaactatcaactggcaatttca attatcgaaacagagacgaaaactgtgtcaatttctttagaagaatcagtagcagatgtt gaactggtttacccagttcttggtttaacaaacacaagtttgacctcacttggagctgtg tacactgaatggaatgttgcctaccattttacaattgctgcaggaaggggaaccaacctg tctctcaaatgtgctcttcttactggtcagacctttacatttaccagttcatgccactcc agtgtttcatccgaggttggtgacaactgtaactcctcaatgtggtggtcagacacacct tttgcaacattcacttacaacacatcagcagtgggaacaatcagcacaaccattgaagta agcaacagtctcagtgctcaatcttataccttgtacatcataacagagaaacgaatcaca ggagtcgtattcagtctcaaaacaccaagccgtttgccaaattgtatacgtaaaggtaca acggctcaatttgacctggaaaatactgagggtacaaatcctagttattcatttaaagta gcaggtgtttcagcggcctcaagaaatgcgtctttattttattcatttccaacaattggt acatttacggttgctgggacaatatctaacaatcttgactctcaaacaaagtcaatcaat gtatctgttaaacaagaagcaagcttcacaaactgtaaattacttgacactccatatatt gcagcggtaggaatcagttttgatttaaagcttcagtgcgaatgctcaattggatcagaa gtgaatacacattggatgtttagtgacagcactgccaacattactactgctgatgttact gttagttcatcaccaaagtcatggacacaggctgttactttcagttcagtctctacagta gatttagctgtatatgcaatggatgctttccaagctgtacttgtgaatggctcagtgaat gtttacaatgcaatacctacaataacagtaacagcaaacagttcaaatgtttttcttaac acagtagtagaaataactgttaatgttccaacaagcccaggaaattactacaacatcaac tacagttatgattttggagatggcagtactaagacaagcgcatctagtgtagttacccat tctttcaccacaggtaataattacacggtgagtgttacagcaagtaatggaccaagcagc cagactgcttctatgaatattgtggtttatgaagctgttacagtcactgcattaacaaat gatggaccaaaacaaacgggaaatcccatcacatttacagcttctgtttcttctggaaat ttcttgtcatacaggtatgtttcttctaactcagccttcgatgtgaccagatccactgga acgtatacacatacctttgcctcagctggtaactatagtgttacagtaactgtttccaac atgctcagtacccagagtgtatcaacacaagcatatgttatgaatgctggagatcttatt atatcaggatttaagattgatggaaatgatgtttcaggctgctatgaatcaactatagga cggagttacaaagtggaccttattcactacagtgttgcaaccatagtctgtgactggaac tttggggacggtcaaacttataccggcacaacttgtcataaaactcatgcttttacaact gcatcaaactttactataactgttactgcaaagtaccacctacacagtgctacagaaact cttagtcaacaagtttgcatacaagaaagaattactactccaacaatgtcaatagaatct accgttactctcccttcatcaggatcagtcaagagaaatgtcactgtagccgtggcaaca ggatcacctttgacgtatgcttggttgacaaatgcaacaggtactacatccacagacgca atccttcccgttgaatttacttcagaagggacatattactttacagttacagtgtcaaat aatgtcaactcagaaacagtgacaaagtctgtcactgttatagaagaattaagtggagta actattgtctgctcatcatgtctcgaaatatcaggcgaatactacatacaaaataatgta gcgacagaattcaaagtaacaacaacaacaggaagtggatcatttgcctgggattttggt gattctacaactggtacaggaatttcaaattttcacacatacacttctatcgacacatat aacgtaactgtcacagcgagcagcatggtcacaacggctgtaacacaatacatcacagtt catgtagaagctgctattacatcagttactatgcaaaatagactttacgactggctgact aataaacgtgattcatctgttaaagatttaaatattttgaatactgggagatttgatgca acagtaacaccagctggaatggatttggattacatttggaaatgtgaatcaggcactatc gaggaaactactcaagtaaatgaatgggatcacaaattcccaacaaaaggctcaaaatct tgtactgttactgtaaaaaactcccttggtaacatgacctcatcagcatttacatttttt gtagttgaaaaattgctagggtctagcctacaagtaacagaaaatgggaacgcgttgact ggcacaaatgagactcatacatacaaggcaaaattaaatgaagtgatcacatttacagta acatcgtcacaaattgttccaaacacagtggaatatttcttacgtcttaaaaagaaaagt acaggttcatctatctatgctttacagaactcaactattgataaagatgatccgacactt tcttacagacttgatgagaatgctttataccagctcgaggcaattgttacaaacagtttg gggccggtgtctatcacagtgtatgtggaagttgtggaagcagtatcaggaccctacatt aaccctgcaccaggcaaagatggaaatattacactaggtagcagcattacattaacaggg ggtgcaactaatggtgaatacaaggagtttaactggttgtatgcatcagcaccaagtgga caggtattacctacaacaacaacatcagacatagtgataacaccttcagtggtaggcttg tatattgtgacattggaagtttctaacgctgtttcaggtcctatcagtgtaaactacaca ataaatgtaatgataggtgtatcgggagtacagatatctgttacaatgccttacactaat gctgtgagagtatataccagtctaacatttactgcacagattgcagctggaaccagtccc tcctacagttggaacgctcttgtctcagggacaacaaatagtacaggaactgctcaaacg tttgtttaccaatttatgtctcaggcactttataacattacactatttgcagaaaattat gcaagtagcggaactgcttacaaagaaatatattctctatatgatgttccaacatttacc ctgtcaatgagtggcgcttcatatattacaagcattagtaaacatgctgcgccatctaat actattataactttctccagcagtataacaaacacagaatacatgcagtttaactggaat attgggggaacatctgtggcagcaactgaaactttgcagaaaaactttactagtgctgca gaatacactgttcagttaactgcaagtaatctaatcagtaatgagaacagccagataagt attctcgtacaggacagtatttctgattttgacgtgcagaattgtataggaacatacatg atgaatactgttataactcttacatcgtcatataaagggactgatatttctgtagattgg actcgtcaaggattggcgagcgtaacaagtgctgctacgactgtccagtattcaactgtt gggatttacagcgtgaatgtaacaggaagaaactatgtgagtcaggagacaaagaactgc tggatatctatccaaggtcctattggtaacttgaatttacaggcatcagtttacaagtat gtggggtatcctattacatttaacgttagcggcgactacatcaatcctgcaattttcacc tgggtgttttcccatggagttaacatgacaacaagtaatagtccaacgctcgacctctca tttacaactagtggaaattatacattaacagtgattgttgcaaatgatgtgagtagctcc agaaagagtataagctttcaggtaaaagatctcggttgtagtgcaccaacagtgacagtg gttggcagtacagataaacgatcaccaagggctcgtgaagtggaaatatcagttgacgta tcaacagggggttgttctagttactcatcatccaatagctggaaagtttattccgcatcc tcctgtgtagcctcgcttcagaatgagtacactcttccaagtacaattaaaacagactta ccaagcattgtgttgcttagcaacacacttaactacggaacatattgtgtggtattccag catacatatgaaaacactcctgttgaggcattcaaatactttaatttgacaatagtcccg tctgatttagtgtctgttctgagcggaggacataaagttggtgtgagggttgcttcaact ttatctctcgatgcaagccagtcttatgatccagataacgttcctgcgacaactctaaat tttgcatggtcctgtacacaaacaatgggatcgtcagcagctgcagctgtctgtaatggt ataagtgcaataacaaatgcatctacaatcttgactggtttgaccttgacagttaatgat gtgtatgttgtcacagtaacagtgtcagctacaggcagaatagccagttccttcacacaa actattactatattgagcaacacagcacctgtaataagtattaactgtgtgtcatgccaa gccaatggacattacttcctgacaagaagccgcagtgtctcatttgaaggtgcttgcatt ggctgtaatacagcaagtcttcagtggacagtgaaagagaattcaactggtacagctgat acaattgacagcactaaaacaacaacagacactaatcagatgaactttgtccttcttagc ggtgtcatacaagataataaggcttatgtttttaaattagaggccactgttggaagtgaa actgggcaggctgagattgttcttgcaccaagctcaaagccttctggaggaatatgcaca cttagtccgtcggcaggtgttgttgcattgacagacacggcgacttactcctgcagtaat gtggtagactcggattcattatcggctatatactacaaagttacagttagatcaactaca tcgtacaagaccccatacattgcttattatggttcaaaatctgtcaacagtatttttgtg gtacctttcccaggaaccaattacagcagtgtacaaatagagatctctgccgtaaacttc tatagagctgaaactgtcttatataccagaactgtatcgtttgttgcaccaaccttatca agtagtcaggctcacaagacagactatatagtggatcagatgttatccaatatgaagacc attgtgaggcagaataaccctccacttctactccagtactgtatgtccgtgctcagttac ctcaacgatcagtcagagaataacgtcggaactctagctcaacgaatggctatccgtgat gttattatgaactccctaagtggtctccccttaacttccatatacaacattcagcagatg gcaacagctatagaatatcttgttgaacatacagaggaggtctctttggccacactttca tctgctctaagtgaaattgaggcgatgacagaacttctagaatctacagtaagcagggga gacgatcagcgagactatgactctaacactttgattaaagcaaatgccaacatgcaacag gcattaaaatctctttcaacagtcacaagtgacagtgctactcttgccaaatttggcagt ctttctgactacgttctgcaggtcagttctagtgtacaaaccacctcgtactccagtgat gaagcccagacacaagcattaatcattaagagcatgaagtcaagcacacaactgttgata ttgcctctccttgcacaggtcgctgatgagaacccaatacagaaagtaacaactgattac gaagtcatggctcgacacgtttccacggacaagattacgcaaaatcacaacagcaattta gggacatctattcaatttccgtcagatatattaacttctcgttacaccgaaccttcagta tttcagattgtttacatcagcaagattattcagtataactttggcttcagtaacctccta ccaaaaaatacgctctcgcttactaccagtttttacaagccatcgggagactcggtcaca gtggataacctttccagtgggaatgaagtgataatgtacatgtttaagaataatgttaca tcatatccaatcaatgacacagcttttcactactcatcaggatacgacccgttattacat atgaattattcgagccgaactctgagtcctgatgccagtttcgcagttaatgttaacatg ccaacagaagcaggtgtgggaattcatattcaactgcgtggaaatttcaccagagctagt gctaaactgtttgcaacattgtacaagaatgatatcaaatttagtgaaactgacagcaat acgaataaaagaccgaaaactatagataaagccatgatggatgatcttaaacacgatcac acagcttacacattcttcatatcaccaagtgattactcaactgacgatgcatttaaagta catcttcgagtctcggaatcaactcaagtactagttggtgtttatcttacaagatgtgaa ttctttaatgaaggtaatgaagagtgggataatgaaggttgcttgccacatcaagattcc atcgcaacatgcatcaaatgtgcgtgtaatcacatgacctcatttggcgggagtttgttt gtgtcacctgacgagctagatttcacagacctttctgaagtggactttgcctcaaaccca gtggctatcattacatgtagtgtgatcctgggactgtatataatcctggtagtagccttc aggaaactggatctgatggacttaaaaaggatctccctcattcctctctgtggtaaagat ggctccttcaaatatgaggttaccatagtaacggggcggttaccaggagcaggtacaaca gctcatgttggtattcgactggtcggagagtacggaaaatcagcccgtcaacatgttatc aaatctggtgcattcaagcggaactgttctgacactttcatcatagcttatgatgtgaac cttggcgagcttaagaagattcaaatatggcacgacaatagaggctcctccccttcctgg tacttgagtcatgtgatcgtaaacgaccttcagacagatcataagttttacttttttggg aacacatggttttcacttgaacaggaaaatggaacaattcaaaaggagctgaaagttgca ggctccaatgacatgagtaaatttagctaccgactaaagacagccatgtttaactccctt gctgataaacatctatggttgtctctattcaaccgtcccgctcagagtcggttcacacgt gtacaacgagtcacatgttgtgtcacaatactgttcacatttgttgtcgttaacgccatg tggtatggtttactaaagaaggacaacacagagctcgggttagaaggtttcggatgggag gaagttgttctggcaatggtcagtaacataatggttcttcctatcagtattggactggtg tatctcttcaagaaaagtcgatcaaagcctaacttctttgaccatgtacacaaaccacag acagctcagacacttgagatagaaaatctgtgtgggaactcgcagagtggatcatttgag agtacaaacacaggagccataccatatgaccttgaaagggagagtaccatcgattctgtc ccacatacagctgcaggactgcatcgttctcgacacgtggcgaagtctcagcgagaaaac acagacgatagcatcattcaaaaacgtccgtctgttgctgtaacaaaggcaagttctaag tcaccattgtggaatgaagataacatcatgaaatggcctgagtcagtaaattacgatgat ggtgcagattcacgtccatctactgcctcaacaatggctgctggaccgtctgtacgtcaa ccaccaggaaaagctggggggtccacacctggagcatcacggaagtcgaagacgttgaag aagggtgatgctggacagttactggatgaactggataaactagaacatgatttgaaggag agtgaatctagatcagttaaatcgagtggcagtaagaaatcatcaaccactcttagacgg ccaacgatgcacaagtcacagtggggcagtttagaagatattctacactccgatgatgag agtgtagcagaaagcagtgccaagatgaggaagcgaggatctacaaccagtcagagtacg atcggaaagttcaatccccgtgctgatcctaggattagcggaaatggtggcatgtggcct gaatcccgagagtctgtgatgagtcgcgagtcaggcggtaggtctggcagaggtataact tcaggacttcgaccgggttattacagtgagatgacgatggaatctagggatatacccgta cacaaggagaaatgctccctaccaccatggtgtatctatatagcatacacactttgtacc ctgcttgtcatcttctcttccatcattgttatcttgtactgtttccggttcgggtaccag gagtctgtgaagtgggtcctggcattgattctctcccttgttctgtccttccttatcatt gagccactcaaggcattgttgattgccgtgtacgtggtcgccacatttaagaaagtagag gaggatgaggatgaagattttattgacattgaaccgaccttcgacaactctaacgaaaaa ataaaggatgtgaaattcaaaccaatatctggatttgctttgctacaagctaaggaggaa ggccgcaaaatccacagaatgaatgttatgattcgacagtttatagcctacgtattctac ctatggctgatcatggtgttggtgtatgtgaacttccaatatgatacgtatctgatgaca aaacacgtagaaaatgactttattgcacctacaaccaatgaccatctcaactttaccaat ataaccactatagacgaattttgggagtggacagagactgtatttattgattcactgtac aaagaaaataatacccaggatgaggaacatgcgttccttcttggagaagccagaatgagg cttataaggggagttacagccaaatgtgaagcagcaaacgcagcatctaacctcggagcc tcgtctctcacggaccgcacttgttacggacagggtaattatgatgaggatactgacgac tatgccgaaggttggaacgacagtaactctaactactcctggagacattactctgctggc gagctcggaagcactcacaagattggacatgtagctacatacggaggtggtggttaccca caaggtctcggtacaacgtctgctgagactgacagtatcatagcccatctgaaggacaaa ggatggatagatcttcaaacacgagctgtcatctttgaatttgccttatacagtgctggc tcagacattacctcaatggttgctttactggccgagttcccgctcaccggtggcgtgatt acaagttacgagatacagagtcagaaactactctggttccagaaagatacagtcgaacct ttaatggttcttgagtgcattttatttttggtgatcatctactctgtcattcacttggcc ttacaaatccgagagtggggtaaacaattcttcaaggacatatggaactggtatgagatg ttgaccacattaatggcactggttagtgtgggaatgtatatcggctgtgtagtagaggcg acaaatacgttcaacagattcctcgacaatcagacaggatttacgaattacgagcgtgct atgtatgtacatgttggaatgagatacctgaatgcttggctactcttccttctaatgttc aaggttgtaaagcagatgagatttatcaagtttatgtacgtgtacgagcgtacattaagc agtgccgtcagtcacctactgggcaccggtctcatctatatcatactacttctagtgtac gcccaggttggatacctgatgtatggccgattcgtctcaggttttgaatcagttggtcat tcaattactacactaattgtaatgatacgtggaagttttgatttctggccaatgcttgac tatcaaccagtgtttagtcatttttacgtgtactcgtactatacttttgcttatggtatc atgatagctctagtcatttcgatattaacgagcacatacaaggtgataaagtcgcagatg tactacaaggccacgctcgagatgcaggactacgagatggtggacttcatgctgaagaga ttcaaacttttgactggtttacagaaacctaaaccagcatttcgtcgggtacgtttccca gggttaccatcagtgtctagtcgaagttcatccagttattctaatcgtagtgcagaacca ttgccgagcgaggagagtgttacagggccgcagtattcagaagttaaactgcgtagcatg atggccagactgggaccaacatggcaagctgtactcagaagaatggacaagattgttgca ttagatgatgaggaagaaagtctagtcaaaaaagcagatgatgaaatgaagaatttgaat tggaagtgccgtataaatgagattgagcggcaacataaagaactattaagctggcagaac cagccatcaacttctgataaacctcctctaggagattcaaagctaagacaatcaatttta aagaggcctggagcctcaaaagacaatcaggatagaaaggcacctgcgacagtgtcaggt gctcagattcggactgcagcctcgacccctgcagatgacggtaatggtgcgcagggtcga cggccgttaagtgatcaaggtgttcgtgtagagccagcctcgacgtcaaagaggcgtgcg tcttccaatgacaagtccaaattacaaacatttttcagaagcattaagccatcaaaatca gcttggaacaaatga

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