Rickettsia prowazekii NMRC Madrid E: H374_4640
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Entry
H374_4640 CDS
T02544
Name
(GenBank) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rpn
Rickettsia prowazekii NMRC Madrid E
Pathway
rpn00300
Lysine biosynthesis
rpn00550
Peptidoglycan biosynthesis
rpn01100
Metabolic pathways
rpn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rpn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
H374_4640
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
H374_4640
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
H374_4640
Enzymes [BR:
rpn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
H374_4640
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-GeneID:
15150240
NCBI-ProteinID:
AGJ01749
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Position
544576..545925
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AA seq
449 aa
AA seq
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MIWNSKTLSIALGIEISNSVNCNEVQFNSKDVKKGDLFIALQGNRDGHDYIQDAIDKGAT
AVIVSKQVEINDKDKIILVNNSFEALQKMALYKRENSKAKFIAITGSVGKTSTKEALKIL
LQHDFIVFASRGNFNNYLGLLINLASMADDTEYAIFELGMNHQGEISELVQILKPNIAMI
NNISEAHLEFFHSLEEIAEAKCEIFKNFSKNDIAIINASNNCYNKILSILKNLSITNIYS
FGHSSKASAKLILYKTLGEQVHLQYYINNKFIDITIPFIPRHFANNYTGVLLIIDILGKD
IEISAKYLADIALTKGRGKIINIQNSRVICDYYNASPQSMKAALEYLKQVPADNKTSIIG
EMLELGWNSQRLHEELVPYILDAGCTKVYLVGAYTKYIYDLLPNKISKKFFKNVEELITH
ITDLFEYSELILIKGSRGVKLDKIVDYYQ
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atgatttggaactctaaaactttaagtattgctcttggtatagaaatctctaattctgtc
aattgtaatgaagtacaatttaactctaaagatgttaaaaaaggtgatttatttatagca
cttcaaggtaatagagatggtcatgattatatccaagatgcaatagataaaggcgcaaca
gcagtaattgttagtaaacaagtagagataaatgataaagataaaattatcttagttaat
aattcttttgaagcgctacaaaaaatggctctatataaacgagagaattcaaaagcgaaa
tttatcgctataaccggtagtgtcggtaaaacttctaccaaagaagcactaaaaatatta
ttacaacatgattttatagtttttgctagcagaggtaattttaataattacttagggtta
cttattaatcttgcatcaatggctgatgatacggaatatgctatttttgagcttggtatg
aatcatcaaggtgaaataagcgaactggttcaaatattaaagccaaatattgctatgatt
aataatatttcagaagctcatttagaattttttcactcacttgaagagatagccgaagct
aaatgtgagatttttaaaaattttagtaaaaatgatattgccattattaatgcaagtaat
aattgttataacaaaatattatcgatattaaaaaatctatctattacaaatatatatagc
tttggtcactcttctaaagcttcagctaaattaattttatataagactctaggagagcaa
gtacacttacagtattatataaataataaattcatagacataactataccattcatccct
aggcatttcgctaacaattacacaggtgtacttttaattatcgatatattaggtaaagat
atagagatatctgcaaagtacttagcagatattgcgcttactaaagggagagggaagatt
atcaatatacaaaattctcgtgtaatttgtgattactataatgcaagtcctcaatcaatg
aaagctgcattagaatatttaaaacaagtgcctgcagataataaaacctctataataggc
gagatgctggagcttggttggaattctcaacgattacatgaggagctagtaccttatata
ctcgatgctggttgtactaaagtttatttagtaggagcatatactaaatatatttatgat
ttactccctaataaaatatctaaaaaattttttaaaaatgttgaagaattgataacgcat
atcactgatttatttgaatatagtgagcttattttaatcaaagggtccagaggtgtaaaa
cttgataagattgttgattattatcaataa
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