Rubrobacter radiotolerans: RradSPS_0140
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Entry
RradSPS_0140 CDS
T03080
Name
(GenBank) leuC: 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
rrd
Rubrobacter radiotolerans
Pathway
rrd00290
Valine, leucine and isoleucine biosynthesis
rrd00660
C5-Branched dibasic acid metabolism
rrd01100
Metabolic pathways
rrd01110
Biosynthesis of secondary metabolites
rrd01210
2-Oxocarboxylic acid metabolism
rrd01230
Biosynthesis of amino acids
Module
rrd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rrd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
RradSPS_0140
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
RradSPS_0140
Enzymes [BR:
rrd01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
RradSPS_0140
4.2.1.35 (R)-2-methylmalate dehydratase
RradSPS_0140
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Motif
Pfam:
Aconitase
NMB1110-like_C
DUF3426
Motif
Other DBs
NCBI-ProteinID:
AHY45423
UniProt:
A0A023WZA2
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Position
143561..144964
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AA seq
467 aa
AA seq
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MSKPKTMAEKVWERHVVRSAPGEPDLLYIDLHMVHEVTSPQAFEALRLAGRTVRRPDLTV
ATMDHNVPTTDFGVPVKDRVSAKQMEALRKNAEDFGIELHGWGSRGQGIVHVIGPEMGLT
QPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLPQRRPKTMAVTIEGELPEDV
TAKDLMLGILNRIGTGGGVGYIIEYRGEAIRNLSMEGRMTICNMTIEGGGRAGMVAPDET
TFEYVKGREHAPKGADWDIAVEEWKNLRTDEGAEFDKEVVIQAEELVPYVSWGTTPAQTV
GLDEAVPEPENEGHERALKYMALEAGTPIREIEVDTVFLGSCTNGRIEDLRAAAKVLQGH
KVKEGIRAMVVPGSMRVKLQAEEEGLDEVFKEAGFDWRNAGCSMCLGMNPDILMPGERCA
STSNRNFEGRQGKGGRTHLVSPVVAAATAVVGRFASPNDLKATTEVK
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgagcaagccaaagacgatggccgagaaggtttgggagcgacacgtggtaaggagcgcg
cccggcgagccggacctgctctacatagacctgcacatggtccacgaggtgacgagcccg
caggcgttcgaggctttgaggctcgcgggaaggacggttcgcagacccgacctgaccgtt
gcgacgatggaccacaacgtgccgacaacggacttcggagtgccggtaaaggaccgcgtc
agcgcaaagcagatggaggctcttaggaagaacgccgaggacttcggcatcgagcttcac
ggctgggggagccgggggcagggaatagtccacgttatcgggccggagatgggcctgaca
cagccggggatgaccatagtgtgcggcgactcgcacaccgccacgcacggagcgttcggg
gcgcttgcgttcgggatcggcacgagcgaggtcgagcacgtgctggctacgcaaacgctc
ccgcaaaggcggccgaagacgatggccgtaacgatcgagggcgagcttccagaggacgta
acggcaaaggacctgatgctcggcatcctgaacaggatcggcaccggcggcggcgtcggc
tacatcatcgagtaccggggcgaggctatccggaacctctcgatggaggggcggatgacg
atctgcaacatgaccatcgagggcggcggacgcgccgggatggtcgccccggacgagacg
accttcgagtacgtgaagggacgcgagcacgccccgaagggcgccgactgggacatcgcg
gtcgaggagtggaagaacctccgaacggacgaaggggccgagttcgacaaggaggtcgtt
atacaggccgaggagcttgtcccgtacgtctcctgggggacgaccccggcccagaccgtc
gggctcgacgaggccgtccccgagcccgagaacgagggccacgagcgcgccctgaagtac
atggcccttgaggcgggcaccccgatccgggagatcgaggtggacaccgtgtttctcggc
tcctgcacgaacggccgcatagaggatctcagggccgcggcgaaggtgctccaagggcac
aaggtcaaggaaggcatccgggcgatggtcgtgccgggctcgatgcgggtgaagctgcag
gccgaggaggaggggctggacgaggtcttcaaggaggccggctttgactggcgcaacgcc
gggtgctcgatgtgcctcggcatgaacccggacatcctcatgcccggcgagcggtgcgcc
tcgacctcgaaccggaacttcgaggggcggcagggcaagggcggccggacgcacctcgtg
agcccggtcgtcgcggcggcgacggcggttgtagggaggttcgcctcgccgaacgacctc
aaggcaacgacggaggtgaagtag
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