KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104656952
Entry
104656952         CDS       T03989                                 
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2
  KO
K18437  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230  Purine metabolism
rro01100  Metabolic pathways
rro04927  Cortisol synthesis and secretion
rro04934  Cushing syndrome
rro05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:rro00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    104656952 (PDE8B)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    104656952 (PDE8B)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    104656952 (PDE8B)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    104656952 (PDE8B)
Enzymes [BR:rro01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     104656952 (PDE8B)
SSDB
Motif
Pfam: PDEase_I PDE8A_N PDE8 PAS_9 PAS PAS_3 PAS_4 PAS_8 DUF4194 DHH
Other DBs
NCBI-GeneID: 104656952
NCBI-ProteinID: XP_010354970
UniProt: A0A2K6P975
LinkDB
Position
3:complement(148695151..148940525)
AA seq 885 aa
MGCAPSIHVSQSGVIYCQDSDESNSPRQTTSVSQGPAAPLPGLYVQTDASDAIPPSRASG
PPSAARARRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITI
NDVPPCISQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAW
FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPGLMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq 2658 nt   +upstreamnt  +downstreamnt
atgggctgcgcccccagcatccatgtctcgcagagcggcgtgatctactgccaggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggtcccgcggcacccctg
cccggcctctacgtccagaccgacgcctccgacgccattcccccaagccgcgcgtccgga
ccccccagcgccgcccgcgcccgcagggcccgcacagagctgggcagcggcagcagcgcg
ggttccgcagcccccgccgcgaccaccagcaggggccggaggcgccactgctgcagcagc
gccgaggccgagactcagaccagctacaccagcgtgaagcaggtgtcttctgcggaggtg
cgcatcgggcccatgagactgacgcaggaccctattcaggttttgctgatctttgcaaag
gaagatagtcagagcgatggcttctggtgggcctgtgacagagctggttatagatgcaat
attgctcggactccagagtcagcccttgaatgctttcttgataagcatcatgaaattatt
gtaattgatcatagacaaactcagaacttcgatgcagaagcagtgtgcaggtcgatccgg
gccacaaatccctctgagcacacggtgatcctcgcagtggtttcacgagtatcggatgac
catgaagaggcgtcagtccttcctcttctccatgcaggcttcaacaggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcccagttcaaattacgggcctgtaattcagtgtttacagcattagatcactgtcatgaa
gccatagaaataacaagcgatgaccacgtgattcagtatgtcaacccagccttcgaaagg
atgatgggctaccacaaaggtgagctcctgggaaaagaactcgctgatctgcccaaaagc
gataagaaccgggcagaccttctcgacaccatcaatacatgcatcaagaagggaaaggag
tggcagggggtttactatgccagacggaaatccggggacagcatccaacagcatgtgaag
atcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactg
tgttgtaccactgacaataataagcagattcacaagattcatcgtgattcaggagacaat
tctcagacagagcctcattcattcagatataagaacaggaggaaagagtccattgacgtg
aaatcgatatcatctcgaggcagtgatgcaccaagcctacagaaccgtcgctatccgtcc
atggcgaggatccactccatgaccatcgaggctcccatcacaaaggttataaatataatc
aatgcagcccaagaaaacagcccagtcacagtagcggaagccttggacagagttctagag
attttacggaccacagaactgtactcccctcagctgggtaccaaagatgaagatccccac
accagtgatcttgttggaggcctgatgactgatggcttgagaaggctgtcaggaaatgag
tatgtgtttactaagaatgtgcaccagagccacagtcaccttgcaatgccaataaccatc
aacgatgttcccccttgtatctctcaattacttgataatgaggagagctgggacttcaac
atctttgaattggaagccgttacgcataaaaggccactggtttacctgggcttaaaggtc
ttctctcggtttggagtatgtgaatttttaaactgttctgaaaccactcttcgggcctgg
ttccaagtgatcgaagccaactaccactcttccaatgcctaccacaactccacccatgct
gccgacgtcctgcacgccaccgctttcttccttggaaaggaaagagtcaagggaagcctc
gatcagctggatgaggtggcagccctcattgctgccacggtccatgatgtggatcacccg
ggaaggaccaactctttcctctgcaatgcaggcagtgagcttgctgtgctctacaatgac
actgctgttctggagagtcaccacaccgccctggccttccagctcaccgtcaaggacacc
aaatgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
attgacatggttttggcaacagagatgacaaaacactttgaacatgtgaataagtttgtg
aacagcatcaacaagccaatggcagctgagattgagggcagcgactgtgaatgcaaccct
gctgggaagaacttccctgaaaaccaaatcctgatcaaacgcatgatgattaagtgtgct
gacgtggccaacccatgccgccccttggacctgtgcattgaatgggctgggaggatctct
gaggagtattttgcacagaccgatgaagagaagagacaggggctacctgtggtgatgcca
gtgtttgacaggaatacctgtagcatccccaagtctcagatctctttcattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacatctgccaggcctgatgcaacat
ttggctgacaactacaaacactggaagacactagatgacctaaagtgcaaaagtctgagg
cttccatctgacagctaa

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