Rhinopithecus roxellana (golden snub-nosed monkey): 104656952
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Entry
104656952 CDS
T03989
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230
Purine metabolism
rro01100
Metabolic pathways
rro04927
Cortisol synthesis and secretion
rro04934
Cushing syndrome
rro05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
104656952 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
104656952 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
104656952 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
104656952 (PDE8B)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
104656952 (PDE8B)
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Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
104656952
NCBI-ProteinID:
XP_010354970
UniProt:
A0A2K6P975
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Position
3:complement(148695151..148940525)
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AA seq
885 aa
AA seq
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MGCAPSIHVSQSGVIYCQDSDESNSPRQTTSVSQGPAAPLPGLYVQTDASDAIPPSRASG
PPSAARARRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITI
NDVPPCISQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAW
FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPGLMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccatgtctcgcagagcggcgtgatctactgccaggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggtcccgcggcacccctg
cccggcctctacgtccagaccgacgcctccgacgccattcccccaagccgcgcgtccgga
ccccccagcgccgcccgcgcccgcagggcccgcacagagctgggcagcggcagcagcgcg
ggttccgcagcccccgccgcgaccaccagcaggggccggaggcgccactgctgcagcagc
gccgaggccgagactcagaccagctacaccagcgtgaagcaggtgtcttctgcggaggtg
cgcatcgggcccatgagactgacgcaggaccctattcaggttttgctgatctttgcaaag
gaagatagtcagagcgatggcttctggtgggcctgtgacagagctggttatagatgcaat
attgctcggactccagagtcagcccttgaatgctttcttgataagcatcatgaaattatt
gtaattgatcatagacaaactcagaacttcgatgcagaagcagtgtgcaggtcgatccgg
gccacaaatccctctgagcacacggtgatcctcgcagtggtttcacgagtatcggatgac
catgaagaggcgtcagtccttcctcttctccatgcaggcttcaacaggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcccagttcaaattacgggcctgtaattcagtgtttacagcattagatcactgtcatgaa
gccatagaaataacaagcgatgaccacgtgattcagtatgtcaacccagccttcgaaagg
atgatgggctaccacaaaggtgagctcctgggaaaagaactcgctgatctgcccaaaagc
gataagaaccgggcagaccttctcgacaccatcaatacatgcatcaagaagggaaaggag
tggcagggggtttactatgccagacggaaatccggggacagcatccaacagcatgtgaag
atcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactg
tgttgtaccactgacaataataagcagattcacaagattcatcgtgattcaggagacaat
tctcagacagagcctcattcattcagatataagaacaggaggaaagagtccattgacgtg
aaatcgatatcatctcgaggcagtgatgcaccaagcctacagaaccgtcgctatccgtcc
atggcgaggatccactccatgaccatcgaggctcccatcacaaaggttataaatataatc
aatgcagcccaagaaaacagcccagtcacagtagcggaagccttggacagagttctagag
attttacggaccacagaactgtactcccctcagctgggtaccaaagatgaagatccccac
accagtgatcttgttggaggcctgatgactgatggcttgagaaggctgtcaggaaatgag
tatgtgtttactaagaatgtgcaccagagccacagtcaccttgcaatgccaataaccatc
aacgatgttcccccttgtatctctcaattacttgataatgaggagagctgggacttcaac
atctttgaattggaagccgttacgcataaaaggccactggtttacctgggcttaaaggtc
ttctctcggtttggagtatgtgaatttttaaactgttctgaaaccactcttcgggcctgg
ttccaagtgatcgaagccaactaccactcttccaatgcctaccacaactccacccatgct
gccgacgtcctgcacgccaccgctttcttccttggaaaggaaagagtcaagggaagcctc
gatcagctggatgaggtggcagccctcattgctgccacggtccatgatgtggatcacccg
ggaaggaccaactctttcctctgcaatgcaggcagtgagcttgctgtgctctacaatgac
actgctgttctggagagtcaccacaccgccctggccttccagctcaccgtcaaggacacc
aaatgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
attgacatggttttggcaacagagatgacaaaacactttgaacatgtgaataagtttgtg
aacagcatcaacaagccaatggcagctgagattgagggcagcgactgtgaatgcaaccct
gctgggaagaacttccctgaaaaccaaatcctgatcaaacgcatgatgattaagtgtgct
gacgtggccaacccatgccgccccttggacctgtgcattgaatgggctgggaggatctct
gaggagtattttgcacagaccgatgaagagaagagacaggggctacctgtggtgatgcca
gtgtttgacaggaatacctgtagcatccccaagtctcagatctctttcattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacatctgccaggcctgatgcaacat
ttggctgacaactacaaacactggaagacactagatgacctaaagtgcaaaagtctgagg
cttccatctgacagctaa
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