Rhinopithecus roxellana (golden snub-nosed monkey): 104659593
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Entry
104659593 CDS
T03989
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00010
Glycolysis / Gluconeogenesis
rro00620
Pyruvate metabolism
rro01100
Metabolic pathways
rro01200
Carbon metabolism
rro01230
Biosynthesis of amino acids
rro04910
Insulin signaling pathway
rro04930
Type II diabetes mellitus
rro04932
Non-alcoholic fatty liver disease
rro04950
Maturity onset diabetes of the young
Module
rro_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
rro_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
104659593 (PKLR)
00620 Pyruvate metabolism
104659593 (PKLR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
104659593 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
104659593 (PKLR)
04950 Maturity onset diabetes of the young
104659593 (PKLR)
04932 Non-alcoholic fatty liver disease
104659593 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
rro04147
]
104659593 (PKLR)
Enzymes [BR:
rro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
104659593 (PKLR)
Exosome [BR:
rro04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
104659593 (PKLR)
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Gene cluster
GFIT
Motif
Pfam:
PK
PK_C
IMPDH
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
104659593
NCBI-ProteinID:
XP_010357969
UniProt:
A0A2K6QEV0
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Position
8:41874593..41886471
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AA seq
574 aa
AA seq
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MSIQENIPSLQRWSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ
LPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS
HGSHEYHAESIANVREAVESFAASPLGYRPVAIALDTKGPEIRTGILQGGPESEVELVKG
SQVLVTVDPAFRTRGNANTVWVDYPNVVGVVPVGGRIYIDDGLISLVVQKIGPEGLVTQV
ENGGVLGSHKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAA
LGPEGQGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC
NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKM
QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRS
AQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESG
KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgtcgatccaggagaacataccatccctgcagcgctggtcatgggtctctaagtcccaa
agagacttagccaagtccatcctgattggagctccaggagggccagcggggtatcttcgg
cgggctagtgtggcccaactgacccaggagctgggcactgccttcttccagcagcagcag
ctgccagctgctatggcagacaccttcctggaacacctctgcctactggacattgactcc
gagcccgtggctgctcgcagtaccagcatcatcgccaccatcgggccggcatctcgctcc
gtggagcgcctcaaggagatgatcaaggccgggatgaacattgcgcgactcaatttctcc
cacggctcccacgagtaccacgctgagtccatcgccaacgtccgggaggcggtggagagc
tttgcagcttccccgctcggctaccggcccgtggccatcgccctggacaccaagggaccg
gagatccgcactgggatcctgcaggggggtccggagtcggaagtggagctggtgaagggc
tcccaggtgctggtgactgtggaccccgcgtttcggacgcgggggaacgcgaacaccgtg
tgggtggactaccccaatgttgtcggggtcgtgccggtggggggccgcatctacattgac
gacgggctcatctccctagtggtccagaaaatcggcccagagggactggtgacccaagtg
gagaacggtggtgtcctgggcagccataaaggcgtgaacttgccgggggcccaggtggac
ttgcccgggctgtccgagcaggacgtccgggacctgcgcttcggggtggagcatggagtg
gacatcgtgtttgcctcctttgtgcggaaagccagcgacgtggctgctgtcagggctgct
ctggggccagaaggacagggcatcaagatcatcagcaaaattgagaaccacgaaggcgtg
aagaggtttgatgaaatcctggaggtgagcgatggcatcatggtggcacggggggaccta
ggcatcgagattccagcagagaaggtttttctggctcagaagatgatgattgggcgctgc
aacttggcgggcaagcctgttgtctgtgccacacagatgctggagagcatgattaccaag
ccccggccaacgagggcagagacaagtgatgtggccaatgctgtgctagatggggccgac
tgcatcatgctgtcaggggagactgccaaaggcaacttccctgtggaagccgtgaagatg
cagcatgcgattgcccgggaggcagaggctgcagtgtaccaccggcagctgtttgaggag
ctacgtcgggcagcaccactgagccgtgatcccactgaggtcaccgccattggcgccgtg
gaggctgccttcaagtgctgtgctgctgccatcatcgtactgaccacaactggccgctca
gcccagcttctgtctcggtaccgacctcgggcagcagtcattgctgtcacccgctctgcc
caagctgcccgccaggtccacttatgccgaggcgtcttccccttgctttaccgtgaacct
ccagaagccatctgggcagatgacgtagatcgccgggtgcaatttggcattgaaagtgga
aagctccgtggcttcctccgtgttggagacctggtgattgtggtgacaggctggcgacct
ggctccggctacaccaacatcatgcgggtgctgagcatatcctga
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