Rhinopithecus roxellana (golden snub-nosed monkey): 104665149
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Entry
104665149 CDS
T03989
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230
Purine metabolism
rro01100
Metabolic pathways
rro04022
cGMP-PKG signaling pathway
rro04740
Olfactory transduction
rro04925
Aldosterone synthesis and secretion
rro05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
104665149 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
104665149 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
104665149 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
104665149 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
104665149 (PDE2A)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
104665149 (PDE2A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
104665149
NCBI-ProteinID:
XP_010365186
UniProt:
A0A2K6R893
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Position
15:59560447..59661433
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AA seq
934 aa
AA seq
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MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAV
KEALSAVLPRVETVYTYLLDGESRLVCEDPPHELPQEGKVWEAIISQKRLGCNGLGLSDL
PGKPLARLVAPLAPHTQVLVIPLVDKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVA
LRRVQALQQRRPSEAPRAVQNPPEGAVEDQKGGAAYTDRDRKILQLCGELYDLDASSLQL
KVLQYLQQETRASRCCLLLVSEDSLQLSCKVIGDKVLGEEISFPLTGCLGQVVEDKKSIQ
LKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDQDEHVIQ
HCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNA
EICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLF
YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGIS
IAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTP
RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHF
CYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVME
RHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG
YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEM
MDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGL
PSNNSLDFLDEEYEVPDLDGTGAPINGCCSLDAE
NT seq
2805 nt
NT seq
+upstream
nt +downstream
nt
atggtcctggtgctgcaccacatcctcatcgctgttgtccaattcctcaggcggggccag
caggtcttcctcaagccggacgagccgccgccgccgccgcagccatgcgccgacagcctg
caggatgctttgctgagtctgggctctgtcatcgacatttcgggcctgcaacgtgctgtc
aaggaggccctgtcagctgtgctcccccgagtggaaactgtctacacctacctgctggat
ggggagtcccggctggtgtgtgaggaccccccacatgaactgccccaggaggggaaagtc
tgggaggctatcatctcccagaagcggctgggctgcaatgggctgggcctctcagacctg
ccagggaagcccttggccaggctggtggctccactggctcctcatacccaagtgctggtc
ataccgctagtggacaaggaggccggggccgtggcagctgtcatcttggtgcactgtggc
cagctgagtgacaatgaggaatggagcctgcaggcagtggagaagcataccttggtggcc
ctgcggagggtgcaggccctgcagcagcgccggcccagcgaggctccccgagccgtccag
aaccccccggagggggcggtggaagaccagaagggcggggcagcgtacaccgaccgcgac
cgcaagatcctgcaactgtgcggggaactctacgacctggatgcctcttccctgcagctc
aaagtgctccaatacctgcagcaggagacccgggcatcccgctgctgcctcctgctggtg
tcggaggacagtctccagctttcttgcaaggtcatcggagacaaagtgctcggggaagag
atcagctttcccttgacaggatgcctgggccaggtggtggaagacaagaagtccatccag
ctgaaggacctcacctctgaggatgtgcaacagctgcagagcatgttgggctgtgagctg
caggccatgctctgtgtccctgtcatcagccgggccactgaccaggtggtggccttggcc
tgcgccttcaacaagctagaaggagacttgttcaccgaccaggatgaacatgttatccag
cattgcttccactacaccagcaccgtgctcaccagcaccctggccttccagaaggaacag
aaactcaagtgtgagtgccaggctcttctccaagtggcaaagaacctcttcacccacctg
gatgacgtctctgtcctgctccaggagatcatcacagaggccagaaacctcagcaatgca
gagatctgctctgtgttcctgctggatcagaatgagctggtggccaaggtgttcgatggg
ggcgtggtggatgatgagagctacgagatccgcatcccggccgatcagggcatcgcggga
cacgtggcgaccacgggccagattctgaacatcccggacgcatatgcccatccgcttttc
taccgcggcgtggacgacagcaccggcttccgcacacgcaacatcctctgcttccccatc
aagaacgagaaccaggaggtcatcggtgtggctgagctggtgaacaagatcaatgggccc
tggttcagcaagttcgacgaggacctggcgacggccttctccatctactgtggcatcagc
atcgcccattctctcctatacaaaaaagtgaatgaggctcagtatcgcagccacctggcc
aatgagatgatgatgtaccacatgaaggtctccgatgatgagtataccaaacttctccat
gatggaatccagcctgtggctgccattgactccaattttgcaagtttcacctatacccct
cgttccctgcccgaggatgacacatccatggccatcctgagcatgctgcaggacatgaat
ttcatcaacaactacaaaattgactgcccgaccctggcccggttctgtttgatggtgaag
aagggctaccgagatcccccctatcacaactggatgcacgccttttctgtctcccacttc
tgctacctgctctacaagaacctggagctcaccaactacctcgaggacatcgagatcttt
gccttgtttatttcctgcatgtgtcacgacctggaccacagaggcacaaacaactctttc
caggtggcctcgaaatctgtgctggctgcgctctacagctccgagggctccgtcatggag
aggcaccactttgctcaggccatcgccatcctcaacacccacggctgcaacatctttgat
catttctcccggaaggactatcagcgcatgctggatctgatgcgggacatcatcttggcc
acggacctggcccaccatctccgcatcttcaaggacctccagaagatggctgaggtgggc
tacgaccgaaacaacaagcagcatcacagactcctcctctgcctcctcatgacctcctgt
gacctctctgaccagaccaagggctggaagaccacgagaaagatcgcggagctgatctac
aaagaattcttctcccagggagacctggagaaggccatgggcaacaggccaatggagatg
atggaccgggagaaggcctatatccccgagctacaaatcagcttcatggagcacattgca
atgcccatctacaagctgttgcaggacctgttccccaaagcagcagagctgtacgagcgc
gtggcctccaaccgtgagcactggaccaaggtgtcccacaagttcaccatccgcggcctc
ccaagtaacaactcgctggacttcctggatgaggagtacgaggtgcctgatctggatggc
actggggcccccatcaatggctgctgcagccttgatgctgagtga
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