Rhinopithecus roxellana (golden snub-nosed monkey): 104668281
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Entry
104668281 CDS
T03989
Symbol
PLAT
Name
(RefSeq) tissue-type plasminogen activator
KO
K01343
tissue plasminogen activator [EC:
3.4.21.68
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04371
Apelin signaling pathway
rro04610
Complement and coagulation cascades
rro05202
Transcriptional misregulation in cancer
rro05215
Prostate cancer
rro05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
104668281 (PLAT)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
104668281 (PLAT)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
104668281 (PLAT)
09162 Cancer: specific types
05215 Prostate cancer
104668281 (PLAT)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
104668281 (PLAT)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rro01002
]
104668281 (PLAT)
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
rro00536
]
104668281 (PLAT)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.68 t-plasminogen activator
104668281 (PLAT)
Peptidases and inhibitors [BR:
rro01002
]
Serine peptidases
Family S1: chymotrypsin family
104668281 (PLAT)
Glycosaminoglycan binding proteins [BR:
rro00536
]
Heparan sulfate / Heparin
Coagulation and fibrinolysis
104668281 (PLAT)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Trypsin
Kringle
fn1
EGF
DUF1986
hEGF
JAG1-like_EGF2
cEGF
Trypsin_2
EGF_C8A_B_C6
Motif
Other DBs
NCBI-GeneID:
104668281
NCBI-ProteinID:
XP_010369248
UniProt:
A0A2K6Q8B5
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All DBs
Position
9:7474247..7506633
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AA seq
562 aa
AA seq
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MNAMKRGLCCVLLLCGAVFALPSQEIHARFRRGARSYQVICRDEETQMIYQQHQSWLRPL
LRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKHCE
IDTRATCYEDQGISYRGTWSIAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCR
NPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGLAYRGTHSLTASGASCLPWN
SMILIGKVYTAQNPNAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCG
LRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQ
ERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDLSHCA
QESSMVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQH
LLNRTVTDNMLCAGDTRSSGPQANLHDACQGDSGGPLVCLNGGRMTLVGIISWGLGCGQK
DVPGVYTKVTNYLDWIQDNMQL
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgaatgcaatgaagagagggctctgctgtgtgctgctgctgtgtggagcagtctttgct
ttgcccagccaggaaatccacgcccgattcagaagaggagccagatcttaccaagtgatc
tgcagagatgaggaaacgcagatgatataccagcaacatcagtcatggctgcgccccttg
ctcagaagcaaccgggtggaatactgctggtgcaacagtggcagggcacagtgccactca
gtgcctgtcaaaagttgcagcgagccaaggtgtttcaatggcggcacctgccagcaggcc
ctgtacttctcagatttcgtgtgccagtgccctgaaggatttgctgggaagcactgtgaa
atagataccagggccacgtgctacgaggaccagggcatcagctacaggggcacgtggagc
atagcagagagcggcgccgagtgtaccaactggaacagcagcgcactggcccagaagccc
tacagcgggcggaggcctgacgccatcaggctgggcttggggaaccacaactactgcaga
aacccagaccgagactcaaagccctggtgctatgtctttaaggcggggaagtacagttcg
gagttctgcagcacccccgcctgctctgagggaaacagtgactgctactttgggaatggg
ttagcctaccgtggcacccacagcctcaccgcatcgggtgcctcctgcctcccgtggaat
tccatgatcctgataggcaaggtttacacagcacagaaccccaatgcccaggcactgggc
ctgggcaaacataattactgccggaatcctgatggggacgccaagccctggtgccacgtg
ctgaagaaccgcaggctgacatgggagtactgtgatgtgccctcctgctccacctgcggc
ctgagacagtacagccagcctcagtttcgcattaaaggagggctcttcgccgacatcgcc
tcccacccctggcaggctgccatctttgccaagcacaggaggtcgccgggagagcggttc
ctgtgtgggggcatactcatcagctcctgctggattctctccgccgcccactgcttccag
gagaggtttccgccccaccacctgacggtgatcttgggcagaacataccgggtggtccct
ggtgaagaagagcagaagtttgaagtagaaaaatacattgtccataaggaattcgatgat
gacacttatgacaatgacattgcgctactgcagctgaaatcagatttgtcccactgtgca
caggagagcagcatggtccgcactgtgtgcctcccgccggcggacctgcagctgccagac
tggactgagtgtgagctctccggctacggcaagcatgaggccttgtctcctttctattca
gagcggctgaaggaggctcatgtcagactgtacccatccagccgctgcacatcacaacat
ttacttaacagaacggtcaccgacaacatgctgtgtgctggagacactcggagcagcggg
ccccaggcgaacctgcacgacgcctgccagggtgattcgggaggccccctggtgtgtctg
aatggtggccgcatgactttggtgggcatcatcagctggggcctgggctgtggacagaag
gatgtcccgggtgtgtacaccaaggtcaccaactacctagactggattcaagacaacatg
caactgtga
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