Rhinopithecus roxellana (golden snub-nosed monkey): 104669588
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Entry
104669588 CDS
T03989
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00140
Steroid hormone biosynthesis
rro01100
Metabolic pathways
rro05215
Prostate cancer
Module
rro_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
104669588 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
104669588 (SRD5A2)
Enzymes [BR:
rro01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
104669588 (SRD5A2)
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GFIT
Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
PEMT
Motif
Other DBs
NCBI-GeneID:
104669588
NCBI-ProteinID:
XP_010370895
UniProt:
A0A2K6RXA3
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Position
17:complement(73602198..73663935)
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AA seq
254 aa
AA seq
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MQVQCQQSPVLAGSATLVALGALVLYVAKPSGYGKHTESLKPAATRLPARAAWFLQELPS
FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVYSLLNRGRPYPAVLIFRGIAFCA
GNGFLQSYYLIYCAEYPDGWYTDIRFCLGVFLFILGMGVNIHSDYILRQLRKPGEITYRI
PQGGVFMYVSGANFLGEIIEWIGYALATWSLPALAFAFFSVCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttcagtgccagcagagcccagtgctggcaggcagcgccactttggtcgctctt
ggggcactggtcttgtacgtcgcgaagccctccggctacgggaagcacacagagagcctg
aagcccgcggctacccgcctgccagcccgcgcagcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgctcggcaacccctctccctcttcgggccacctggg
acggtgcttctgggcctcttctgcgtacattacttccacaggacatttgtgtactcactg
ctcaatcgagggaggccttatccagctgtactcattttcagaggcattgccttctgcgct
ggaaatggattccttcaaagctactatctgatttactgtgctgaataccctgatgggtgg
tacacagacatacggttttgcttaggtgtcttcttatttattttgggaatgggagtcaac
atccatagtgactatatattgcgccagctcaggaagcctggagaaatcacctacaggatt
ccacaaggtggcgtgtttatgtatgtttccggagccaatttcctcggtgagatcattgaa
tggatcggctatgcgctggccacttggtccctcccagcacttgcatttgcttttttctca
gtttgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaagcccttattccattcatcttttaa
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