Rhinopithecus roxellana (golden snub-nosed monkey): 104669989
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Entry
104669989 CDS
T03989
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230
Purine metabolism
rro01100
Metabolic pathways
rro04024
cAMP signaling pathway
rro05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
104669989 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
104669989 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
104669989 (PDE10A)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
104669989 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
104669989 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
104669989
NCBI-ProteinID:
XP_030785330
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Position
4:152453023..152815744
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AA seq
791 aa
AA seq
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MEGSTPWSSEAEPQEERSQMPQRAGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLK
RKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATK
ADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTISAYVAKSRKTLLVEDIL
GDERFPKGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLA
WASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCA
LFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYA
DPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFC
ALALHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQDLMRFTLPVRLCKEIELFHFD
IGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMY
AILQNNHALFTDLERKGLLIACLCHDLDHRGFSNTYLQKFDHPLAALYSTSTMEQHHFSQ
TVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNN
QSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDK
KDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETATWISSP
SVAQKAAASED
NT seq
2376 nt
NT seq
+upstream
nt +downstream
nt
atggaagggagcacgccctggagttcagaagccgagcctcaagaggaaagaagccagatg
ccccagagagcaggtttgacagatgaaaaagtgaaggcatatctttctcttcacccccag
gtattagatgaatttgtatctgaaagtgttagtgcagagacagtagagaaatggctgaag
aggaagaacaacaaatcagaagatgaatcggctcctaaggaagtcagcaggtaccaagat
acgaatatgcagggagttgtatatgaactaaacagctatatagaacaacggttggacaca
ggaggagacaaccagctactcctctatgaactgagcagcatcatcaaaatagccacaaaa
gctgatggatttgcattgtatttccttggagagtgcaataatagcctgtgcatattcaca
ccacctgggataaaggaaggaaaaccccgcctcatccctgctgggcccattactcagggc
accaccatctctgcttatgtggccaagtccaggaaaacattgctagtagaagacatcctt
ggagatgaacgatttccaaaaggtactggactggaatcagggactcgtatccagtctgtt
ctttgcttaccgattgtcactgcaattggtgacttgattggtattcttgagctgtatcgg
cactggggcaaagaagccttctgtcttagtcaccaggaggttgcaacagcaaatcttgcc
tgggcttcagtagcaatacatcaggtgcaggtatgcagaggccttgccaaacagactgaa
ttgaatgactttctactcgacgtatcaaaaacatattttgataacatagttgcaatagat
tctctacttgaacacataatgatatatgcaaaaaacctggtgaatgccgaccgttgtgca
cttttccaggtagaccataagaacaaggagttatattcagacctttttgatatcggagag
gaaaaggaaggaaaacctgtcttcaagaagaccaaagagataagattttcaattgagaaa
ggaattgctggccaagtagcaagaacaggggaagtcctgaacattccagatgcctatgca
gacccacgctttaacagagaagtagacttgtacacaggctacaccacacggaacatcctg
tgcatgcccatcgtcagccgaggcagcgtgataggtgtggtgcagatggtcaacaaaatc
agtggcagtgccttctctaaaaccgatgaaaataacttcaaaatgtttgccgtcttttgt
gctttagccttacactgtgctaatatgtatcatagaattcgccactcagagtgcatttac
cgggtaacgatggaaaagctgtcctaccatagcatttgtactgcagaagagtggcaagac
ctcatgcgattcacccttcctgtgcgtctctgcaaagaaattgaattattccactttgac
attggtccttttgaaaacatgtggcctggaatttttgtctacatggttcatcggtcctgt
gggacatcctgctttgagctcgaaaagttgtgtcgttttattatgtctgtgaagaagaat
tatcggcgggttccttatcacaactggaagcatgcggtcactgtagcccactgcatgtac
gccatacttcagaacaatcacgcgcttttcacagaccttgagcgcaaaggactgctgatt
gcgtgtctgtgtcatgacctagaccacaggggctttagtaacacctacctgcagaagttc
gaccaccctctagcagctctctactccacttccaccatggaacagcaccacttctcccag
accgtgtccatcctccagttggaagggcacaatatcttctccactctgagctccagtgaa
tacgagcaggtgcttgagatcatccgcaaagccatcattgccacagaccttgctttatac
tttggaaacaggaaacagttggaagagatgtaccagaccggatcgctaaaccttaataat
caatcacatagagaccgtgtaattggtttgatgatgacggcctgtgacctttgttctgtg
acaaaactgtggcccgttacaaaattgacggcaaatgatatatatgcagaattctgggct
gagggtgatgaaatgaagaaattgggaatacagcctattcctatgatggacagagacaag
aaggatgaagtcccccaaggccagcttgggttctacaatgctgtagccattccctgctac
acaacccttacccagatcctccctcccacggagcctctccttaaagcatgcagggataat
ctcaatcagtgggagaaggtgattcgaggagaggagactgcaacctggatttcatcccca
tccgtggctcagaaggcagctgcatctgaagactga
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