Rhinopithecus roxellana (golden snub-nosed monkey): 104673299
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Entry
104673299 CDS
T03989
Symbol
RAF1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X2
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01521
EGFR tyrosine kinase inhibitor resistance
rro01522
Endocrine resistance
rro04010
MAPK signaling pathway
rro04012
ErbB signaling pathway
rro04014
Ras signaling pathway
rro04015
Rap1 signaling pathway
rro04022
cGMP-PKG signaling pathway
rro04024
cAMP signaling pathway
rro04062
Chemokine signaling pathway
rro04068
FoxO signaling pathway
rro04071
Sphingolipid signaling pathway
rro04072
Phospholipase D signaling pathway
rro04140
Autophagy - animal
rro04150
mTOR signaling pathway
rro04151
PI3K-Akt signaling pathway
rro04210
Apoptosis
rro04218
Cellular senescence
rro04270
Vascular smooth muscle contraction
rro04360
Axon guidance
rro04370
VEGF signaling pathway
rro04371
Apelin signaling pathway
rro04510
Focal adhesion
rro04540
Gap junction
rro04550
Signaling pathways regulating pluripotency of stem cells
rro04613
Neutrophil extracellular trap formation
rro04625
C-type lectin receptor signaling pathway
rro04630
JAK-STAT signaling pathway
rro04650
Natural killer cell mediated cytotoxicity
rro04660
T cell receptor signaling pathway
rro04662
B cell receptor signaling pathway
rro04664
Fc epsilon RI signaling pathway
rro04666
Fc gamma R-mediated phagocytosis
rro04720
Long-term potentiation
rro04722
Neurotrophin signaling pathway
rro04726
Serotonergic synapse
rro04730
Long-term depression
rro04810
Regulation of actin cytoskeleton
rro04910
Insulin signaling pathway
rro04912
GnRH signaling pathway
rro04914
Progesterone-mediated oocyte maturation
rro04915
Estrogen signaling pathway
rro04916
Melanogenesis
rro04917
Prolactin signaling pathway
rro04919
Thyroid hormone signaling pathway
rro04921
Oxytocin signaling pathway
rro04926
Relaxin signaling pathway
rro04928
Parathyroid hormone synthesis, secretion and action
rro04929
GnRH secretion
rro04935
Growth hormone synthesis, secretion and action
rro05010
Alzheimer disease
rro05022
Pathways of neurodegeneration - multiple diseases
rro05034
Alcoholism
rro05132
Salmonella infection
rro05152
Tuberculosis
rro05160
Hepatitis C
rro05161
Hepatitis B
rro05163
Human cytomegalovirus infection
rro05164
Influenza A
rro05165
Human papillomavirus infection
rro05167
Kaposi sarcoma-associated herpesvirus infection
rro05170
Human immunodeficiency virus 1 infection
rro05200
Pathways in cancer
rro05205
Proteoglycans in cancer
rro05206
MicroRNAs in cancer
rro05207
Chemical carcinogenesis - receptor activation
rro05208
Chemical carcinogenesis - reactive oxygen species
rro05210
Colorectal cancer
rro05211
Renal cell carcinoma
rro05212
Pancreatic cancer
rro05213
Endometrial cancer
rro05214
Glioma
rro05215
Prostate cancer
rro05218
Melanoma
rro05219
Bladder cancer
rro05220
Chronic myeloid leukemia
rro05221
Acute myeloid leukemia
rro05223
Non-small cell lung cancer
rro05224
Breast cancer
rro05225
Hepatocellular carcinoma
rro05226
Gastric cancer
rro05230
Central carbon metabolism in cancer
rro05231
Choline metabolism in cancer
rro05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
104673299 (RAF1)
04012 ErbB signaling pathway
104673299 (RAF1)
04014 Ras signaling pathway
104673299 (RAF1)
04015 Rap1 signaling pathway
104673299 (RAF1)
04370 VEGF signaling pathway
104673299 (RAF1)
04371 Apelin signaling pathway
104673299 (RAF1)
04630 JAK-STAT signaling pathway
104673299 (RAF1)
04068 FoxO signaling pathway
104673299 (RAF1)
04072 Phospholipase D signaling pathway
104673299 (RAF1)
04071 Sphingolipid signaling pathway
104673299 (RAF1)
04024 cAMP signaling pathway
104673299 (RAF1)
04022 cGMP-PKG signaling pathway
104673299 (RAF1)
04151 PI3K-Akt signaling pathway
104673299 (RAF1)
04150 mTOR signaling pathway
104673299 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
104673299 (RAF1)
09143 Cell growth and death
04210 Apoptosis
104673299 (RAF1)
04218 Cellular senescence
104673299 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
104673299 (RAF1)
04540 Gap junction
104673299 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
104673299 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
104673299 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
104673299 (RAF1)
04625 C-type lectin receptor signaling pathway
104673299 (RAF1)
04650 Natural killer cell mediated cytotoxicity
104673299 (RAF1)
04660 T cell receptor signaling pathway
104673299 (RAF1)
04662 B cell receptor signaling pathway
104673299 (RAF1)
04664 Fc epsilon RI signaling pathway
104673299 (RAF1)
04666 Fc gamma R-mediated phagocytosis
104673299 (RAF1)
04062 Chemokine signaling pathway
104673299 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
104673299 (RAF1)
04929 GnRH secretion
104673299 (RAF1)
04912 GnRH signaling pathway
104673299 (RAF1)
04915 Estrogen signaling pathway
104673299 (RAF1)
04914 Progesterone-mediated oocyte maturation
104673299 (RAF1)
04917 Prolactin signaling pathway
104673299 (RAF1)
04921 Oxytocin signaling pathway
104673299 (RAF1)
04926 Relaxin signaling pathway
104673299 (RAF1)
04935 Growth hormone synthesis, secretion and action
104673299 (RAF1)
04919 Thyroid hormone signaling pathway
104673299 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
104673299 (RAF1)
04916 Melanogenesis
104673299 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
104673299 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
104673299 (RAF1)
04720 Long-term potentiation
104673299 (RAF1)
04730 Long-term depression
104673299 (RAF1)
04722 Neurotrophin signaling pathway
104673299 (RAF1)
09158 Development and regeneration
04360 Axon guidance
104673299 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104673299 (RAF1)
05206 MicroRNAs in cancer
104673299 (RAF1)
05205 Proteoglycans in cancer
104673299 (RAF1)
05207 Chemical carcinogenesis - receptor activation
104673299 (RAF1)
05208 Chemical carcinogenesis - reactive oxygen species
104673299 (RAF1)
05230 Central carbon metabolism in cancer
104673299 (RAF1)
05231 Choline metabolism in cancer
104673299 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
104673299 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
104673299 (RAF1)
05212 Pancreatic cancer
104673299 (RAF1)
05225 Hepatocellular carcinoma
104673299 (RAF1)
05226 Gastric cancer
104673299 (RAF1)
05214 Glioma
104673299 (RAF1)
05221 Acute myeloid leukemia
104673299 (RAF1)
05220 Chronic myeloid leukemia
104673299 (RAF1)
05218 Melanoma
104673299 (RAF1)
05211 Renal cell carcinoma
104673299 (RAF1)
05219 Bladder cancer
104673299 (RAF1)
05215 Prostate cancer
104673299 (RAF1)
05213 Endometrial cancer
104673299 (RAF1)
05224 Breast cancer
104673299 (RAF1)
05223 Non-small cell lung cancer
104673299 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
104673299 (RAF1)
05161 Hepatitis B
104673299 (RAF1)
05160 Hepatitis C
104673299 (RAF1)
05164 Influenza A
104673299 (RAF1)
05163 Human cytomegalovirus infection
104673299 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
104673299 (RAF1)
05165 Human papillomavirus infection
104673299 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
104673299 (RAF1)
05152 Tuberculosis
104673299 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
104673299 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
104673299 (RAF1)
09165 Substance dependence
05034 Alcoholism
104673299 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
104673299 (RAF1)
01522 Endocrine resistance
104673299 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rro01001
]
104673299 (RAF1)
Enzymes [BR:
rro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
104673299 (RAF1)
Protein kinases [BR:
rro01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
104673299 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
104673299
NCBI-ProteinID:
XP_010375599
UniProt:
A0A2K6R7G0
LinkDB
All DBs
Position
1:complement(93241606..93326867)
Genome browser
AA seq
668 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDAVFDGSSCISPTLVQQFGYQRRASDDGKLTDASKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIENNNLNASPRAWSRRFCLRGRDA
IRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSY
YWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVNPTPEQFQAFRNEVAVLRKT
RHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH
AKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQ
DNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKA
MKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLT
TSPRLPVF
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggagcttggaagacgatcagcaatggttttggattcaaagatgcc
gtgtttgatggctccagctgcatctctcctacattagttcagcagtttggctatcagcgc
cgggcatcagatgatggcaaactcacagatgcttctaagacaagcaacactatccgtgtt
ttcttgccaaacaagcaaagaacagtggtcaatgtgcgaaatggaatgagcttgcatgac
tgccttatgaaagcactcaaggtgaggggccttcaaccagagtgctgtgcagtgttcaga
cttctccacgaacacaaaggtaaaaaagcacgcttagattggaatactgatgctgcctct
ttgattggggaagaacttcaagtagatttcctggatcatgttccgcttacaacacacaac
tttgctcggaagacgttcctgaagcttgccttctgtgacatctgtcagaaattcctgctc
aatggatttcgatgtcaaacttgtggctacaaatttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttattgtttccaaattccact
attggtgatagtggagtcccagcactaccttctttgactatgcgtcgtatgcgagagtct
gtttccaggatgcctgttagttctcagcacaggtattctacacctcacgccttcaccttt
aacacctccagtccctcatctgaaggttccctgtcccagaggcagaggtcgacgtccaca
cctaatgtccacatggtcagcaccaccctgcctgtggacagcaggatgattgagaataac
aacctgaatgcttctcccagggcgtggtccagacgattttgtttgaggggaagagatgca
attcgaagtcacagcgaatcagcctcaccttcagccctgtccagtagccccaacaatctg
agcccaacaggctggtcacagccgaaaacacccgtgccagcacaaagagagcgggcacca
gtatctgggacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctgtccactcggattgggtcaggctctttt
ggaactgtttataagggcaaatggcatggagacgttgcagtaaagatcctaaaggttgtc
aacccaaccccagagcaattccaggccttcaggaatgaggtggctgttctgcgcaaaaca
cggcatgtgaacattctgcttttcatggggtacatgacaaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctctacaaacacctgcatgtccaggagaccaagttt
cagatgttccagctaattgacattgcccgacagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggccta
acagtgaaaattggagattttggtttggcaacagtaaagtcacgctggagtggttctcag
caggttgaacaacctactggctctgtcctgtggatggccccagaggtgatccgaatgcag
gataacaacccattcagtttccagtcggatgtctactcctatggcatcgtattatatgag
ctgatgacgggggaacttccttactctcacatcaacaaccgagatcagatcatcttcatg
gtgggccgagggtatgcctccccagatcttagtaagctatataagaactgccccaaagca
atgaagaggctggtagctgactgtgtgaagaaagtaaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctgctccaacactctctaccgaagatcaaccggagcgct
tccgagccatccttgcatcgggcagcccacactgaggatatcaatgcttgcacgctgacc
acgtcccctaggctgcctgtcttctag
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integrated database retrieval system