Rhinopithecus roxellana (golden snub-nosed monkey): 104674338
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Entry
104674338 CDS
T03989
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X2
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00020
Citrate cycle (TCA cycle)
rro00480
Glutathione metabolism
rro01100
Metabolic pathways
rro01200
Carbon metabolism
rro01210
2-Oxocarboxylic acid metabolism
rro01230
Biosynthesis of amino acids
rro04146
Peroxisome
rro05230
Central carbon metabolism in cancer
Module
rro_M00009
Citrate cycle (TCA cycle, Krebs cycle)
rro_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
104674338 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104674338 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
104674338 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
104674338 (IDH2)
Enzymes [BR:
rro01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
104674338 (IDH2)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
104674338
NCBI-ProteinID:
XP_010376918
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Position
5:complement(119957456..119975509)
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AA seq
322 aa
AA seq
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MWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAG
TFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMST
KNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKN
YDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIA
SIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEH
FLNTTDFLDTIKSNLDRALGRQ
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atgtggaaaagtcccaatggaactatccggaacatcctgggggggactgtcttccgggag
cccatcatctgcaaaaacatcccacgccttgtccctggctggaccaagcccatcaccatt
ggcaggcacgcccatggcgaccagtacaaggccacagactttgtggcagaccgggctggc
acgttcaaaatggtcttcaccccgaaagatggcagcggtgtcaaggagtgggaagtgtac
aacttccccgcaggcggtgtgggcatgggcatgtacaacaccgatgagtccatctcgggt
ttcgcgcacagctgcttccagtatgccatccagaagaaatggccgctgtacatgagcacc
aagaacaccatactgaaagcctacgatgggcgtttcaaggacatcttccaggagatcttt
gacaagcactataagaccgacttcgacaagaataagatctggtatgaacaccggctcatt
gatgacatggtggctcaggtcctcaagtcttcgggcggctttgtgtgggcctgcaagaac
tatgacggagatgtgcagtcagacatcctggcccagggctttggctctcttggcctgatg
acgtctgtcctggtctgccctgatgggaagacgattgaggctgaggctgctcatgggacc
gtcacccgccactatcgggagcaccagaagggccggcccaccagcaccaaccccatcgcc
agcatctttgcctggacgcgtggtctggagcaccgagggaaactggatgggaaccaggac
ctcatcaggtttgcccagacgctggagaaggtgtgcgtggagacggtggagagcggagcc
atgaccaaggacctggcaggctgcattcatggcctcagcaatgtgaagctgaacgagcac
ttcctgaacaccacagacttcctcgacaccatcaagagcaacctggacagagccctgggc
aggcagtag
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