Rhinopithecus roxellana (golden snub-nosed monkey): 104675499
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Entry
104675499 CDS
T03989
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04140
Autophagy - animal
rro04141
Protein processing in endoplasmic reticulum
rro04210
Apoptosis
rro04932
Non-alcoholic fatty liver disease
rro05010
Alzheimer disease
rro05012
Parkinson disease
rro05014
Amyotrophic lateral sclerosis
rro05016
Huntington disease
rro05017
Spinocerebellar ataxia
rro05022
Pathways of neurodegeneration - multiple diseases
rro05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
104675499 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
104675499 (ERN1)
09143 Cell growth and death
04210 Apoptosis
104675499 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
104675499 (ERN1)
05012 Parkinson disease
104675499 (ERN1)
05014 Amyotrophic lateral sclerosis
104675499 (ERN1)
05016 Huntington disease
104675499 (ERN1)
05017 Spinocerebellar ataxia
104675499 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
104675499 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
104675499 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
104675499 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rro01001
]
104675499 (ERN1)
Enzymes [BR:
rro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
104675499 (ERN1)
Protein kinases [BR:
rro01001
]
Serine/threonine kinases: Other
IRE family
104675499 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
CytochromB561_N
Motif
Other DBs
NCBI-GeneID:
104675499
NCBI-ProteinID:
XP_030778818
LinkDB
All DBs
Position
19:complement(77403621..77494985)
Genome browser
AA seq
979 aa
AA seq
DB search
MPARRLLLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLR
KVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKSKNKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTV
SRDVEEKPAHAPARPEAPVDSVLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQ
FQKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPNTSPRASNHSLC
SGSSASKAGSSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAV
KRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF
AHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKL
AAGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKS
LQRQANILLGACSLECLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQ
LQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVR
DLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQ
PYYFHRLPEPQPPVTPDAL
NT seq
2940 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgctgctgctgctgctgctgacgctactgctgcccggcctcggg
atttttggaagtaccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacgctg
gatggaagtttgcatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaa
gatccagtcctacaggtcccaacgcatgtggaagagcctgcctttctcccagatcctaat
gatggcagcctgtatacgcttggaagcaagaataatgaaggcctgacgaaacttcctttt
accatcccagaattggtgcaggcatctccgtgccgaagttcagatggaatcctctacatg
ggtaaaaagcaggacatctggtatgttattgacctcctgactggggagaagcagcagacc
ttgtcatcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcga
acagaatacaccatcaccatgtacgacaccaaaacccgagagctccggtggaatgccacc
tactttgactacgcagcctcactgcccgaggacgacatggactacaagatgtcccacttt
gtgtccaatggtgatgggctggtggtgaccgtggacagtgaatctggggatgtcctgtgg
atccaaaactacgcctcccctgtggtggccttttatgtatggcagcgggagggtctcagg
aaggtgatgcacatcaatgtcgctgtggagaccctgcgctatctgaccttcatgtctggg
gaggtggggcgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagc
aagctgacgcccactctgtatgttgggaaatactctaccagcctctatgcctctccctca
atggtacacgagggagttgctgtcgtgccccgcggcagcacacttcctttgctggaaggg
ccccagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcaca
gacctcaagtttgatcccggactcaaaagcaagaacaagctcaactacttgaggaattac
tggcttctgataggccaccatgaaaccccactgtctgcgtctaccaagatgctggagaga
ttccccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaag
agctttgaggaagttatcaacctggttgaccagacttcagaaaacgcacctaccaccgtg
tctcgggatgtggaggagaagcccgcccatgcccctgcccggcccgaggcccccgtggac
tccgtgctcaaggacgtggccaccatcatcctgagcaccttcctgctgattggctgggtg
gccttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcag
ttccagaaggaactggagaagattcagctcctgcagcagcagcagcagcagctacccttc
cacccacctggagacacggctcaggacggcgagcttctggacacatctggcccatactca
gagagctcgggcaccagcagccccaacacgtcccccagggcctccaaccactcgctctgc
tccggcagctctgcctccaaggctggcagcagcccctccctggagcaagacgacggagat
gaggaaaccagcatggtgatagttgggaaaatttccttctgtcccaaggacgtcctgggc
catggagctgagggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtg
aagaggatcctccccgagtgttttagcttcgcagaccgtgaggtccagctgttgcgagaa
tcagatgagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccag
tacattgccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggacttt
gcgcatctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccac
cttcactccctcaacatcgttcacagagacctaaagccccacaacattctcatatccatg
cccaatgcacatggcaagatcaaggccatgatctctgactttggcctgtgcaagaagctg
gcagcgggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggata
gctccagagatgctgagcgaagactgtaaggagaaccctacctacacggtggacatcttt
tctgcaggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtcc
ctgcagcggcaggccaacatcctcctgggtgcctgcagcctcgagtgcttgcacccagag
aagcacgaagacgtcattgcacgtgaattgatagagaagatgattgcgatggatcctcag
aaacgcccctcagcgaagcacgtgctgaaacacccattcttctggagcctagagaagcag
ctccagttcttccaggacgtgagtgacagaatagaaaaggaatccctggatggcccgatt
gtgaaacagttagagagaggcgggagagccgtggtgaagatggactggcgggagaacatc
accgtccccctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcaga
gatctcctccgagccatgagaaataagaagcaccactaccgggaactgcctgcagaggtg
cgggagacgctggggtccctccctgatgacttcgtgtgctacttcacgtctcgcttcccc
cacctcctcgcacacacctaccgggccatggagctgtgcagccacgagagactcttccag
ccctactacttccacaggctcccagagccccagcccccagtgactccagatgccctctga
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