Rhinopithecus roxellana (golden snub-nosed monkey): 104677430
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Entry
104677430 CDS
T03989
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230
Purine metabolism
rro01100
Metabolic pathways
rro04934
Cushing syndrome
rro05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
104677430 (PDE11A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
104677430 (PDE11A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
104677430 (PDE11A)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
104677430 (PDE11A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
104677430 (PDE11A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD-CE
HD
Motif
Other DBs
NCBI-GeneID:
104677430
NCBI-ProteinID:
XP_010380758
UniProt:
A0A2K6NWU0
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Position
14:69962030..70444375
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AA seq
933 aa
AA seq
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MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSS
LAHSTCKGGSSVGGGIGPNGSAHSQPLPGGGDCGGVPLSPSWASGSRGDGNLQRRASQKE
LRKSFARSKAIHMNRTYDEQATSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVERAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELLSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAA
NRSKWEELHQKRLLASTASSSPASVMVATEDRN
NT seq
2802 nt
NT seq
+upstream
nt +downstream
nt
atggcagcctcccgcctggactttggggaggtggaaactttcctggacaggcacccagag
ttgtttgaagattacttgatgcggaaggggaagcaggagatggttgaaaagtggctgcag
aggcatagtcagggtcagggggctttaggtccaaggccctctttggctggtaccagcagc
ttggctcacagcacctgcaaaggtggcagcagcgttggtggtggcattggaccaaatggc
tctgcccatagccagcctcttcccggtggtggggactgtggtggggttcccttgagtccc
agctgggccagtggcagcaggggtgatgggaacctgcagcggagagcttctcagaaagag
ctaaggaagagttttgcccgctccaaggccatccacatgaacaggacttacgatgaacag
gcgacctcccgggctcaggaacccctgagcagtgtacgacggagggcacttctccggaag
gccagctccctgccccccaccacagcccatattctcagtgcgctgctggaatcgagagtg
aatctgcctcagtatcctcctacagccatcgactacaagtgccacctgaaaaagcataat
gagcgtcagttctttctggaattggtcaaagatatctccaatgaccttgacctcaccagc
ctgagctacaagattcttatctttgtctgccttatggtggacgctgaccgctgctctctt
ttcctggtggaaagggcagctgctggcaagaagagcttggtctccaaattctttgatgtg
catgcaggaacccctctgctgccttgcagcagcacagagaactcaaatgaggtgcaggtc
ccctggggcaaaggcatcattggctatgtcggggagcatggagaaacggtcaacattcct
gatgcctaccaggatcgacgattcaatgatgaaatcgacaagctaactggatacaagaca
aaatcattattgtgcatgcctatccgaagcagtgatggtgagattattggtgtggcccaa
gcgataaataagattcctgaaggagctccatttactgaagatgatgaaaaagttatgcag
atgtatcttccattttgtggaatcgccatatctaacgctcagctctttgctgcctcaagg
aaagaatatgaaagaagcagagctttgctagaggtcgttaatgacctctttgaagaacaa
actgacctggagaaaattgtcaagaaaataatgcatcgggcccaaactctgctgaaatgt
gaacgctgttctgttttactcctagaggacatcgaatcaccagtggtgaaatttaccaaa
tcctttgaattgctgtccccgaagtgcagtgctgatgctgagaacagtttcaaagaaagc
atggagaaatcatcgtactctgactggctaataaataacagcattgctgagctggttgct
tcaacaggcctcccagtgaatatcagtgatgcctaccaggatccgcgctttgatgcagag
gcggaccagatatctggttttcacataagatctgttctctgtgtccctatttggaatagc
aaccaccaaataattggagtggctcaagtgttaaatagacttgatgggaaaccttttgat
gatgcggatcaacgactttttgaggcttttgtcatcttttgtggacttggcatcaacaac
acaattatgtatgatcaagtgaagaagtcctgggccaagcagtctgtggctcttgatgtg
ctatcatatcatgcaacatgttcaaaagctgaagttgacaagtttaaggcagccaacatc
cctctggtgtcagaacttgccatcgatgacattcattttgatgacttttctcttgacgtt
gatgccatgatcacagctgctctccggatgttcatggagctggggatggtacagaaattt
aaaattgactatgagacactgtgtaggtggcttttgacagtgaggaaaaactatcggatg
gttctgtaccacaactggagacatgccttcaacgtgtgtcagctgatgttcgcgatgtta
accactgctgggtttcaagagattctgaccgaggtggaaattttagccgtgattgtggga
tgcctatgtcatgacctcgaccacaggggaaccaacaatgccttccaagctaagagcggt
tccgccctggcccaactctatggaacctctgctaccttggagcatcaccatttcaaccac
gctgtgatgatccttcaaagtgagggtcacaatatctttgctaacctgtcctccaaggaa
tatagtgaccttatgcagcttttgaagcagtcaatattggcaacagacctcacgctgtac
tttgagaggagaactgaattctttgaacttgtcagtaaaggagaatacgattggaacatc
aaaaaccaccgtgatgtatttcgatcaatgttaatgacagcctgtgaccttggagccgtg
accaaaccgtgggagatctcgagacaggtggcagaacttgtaaccagtgagttcttcgaa
caaggagatcgggagagattagagctcaaactcactccttcggcaatttttgatcggaac
cggaaagatgaactgcctcggttgcaactggagtggattgatagcatctgcatgcctttg
tatcaggcactggtgaaggtcaatgtgaaactgaagccgatgctagattcagtagctgca
aacagaagtaagtgggaagagctgcaccaaaaacggctgctggcctcaactgcctcatcc
tcccctgccagtgttatggtagccacggaagacaggaactaa
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