Rhinopithecus roxellana (golden snub-nosed monkey): 104681538
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Entry
104681538 CDS
T03989
Symbol
TSC2
Name
(RefSeq) tuberin isoform X1
KO
K07207
tuberous sclerosis 2
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04072
Phospholipase D signaling pathway
rro04115
p53 signaling pathway
rro04140
Autophagy - animal
rro04150
mTOR signaling pathway
rro04151
PI3K-Akt signaling pathway
rro04152
AMPK signaling pathway
rro04211
Longevity regulating pathway
rro04218
Cellular senescence
rro04714
Thermogenesis
rro04910
Insulin signaling pathway
rro04919
Thyroid hormone signaling pathway
rro05163
Human cytomegalovirus infection
rro05165
Human papillomavirus infection
rro05168
Herpes simplex virus 1 infection
rro05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
104681538 (TSC2)
04151 PI3K-Akt signaling pathway
104681538 (TSC2)
04152 AMPK signaling pathway
104681538 (TSC2)
04150 mTOR signaling pathway
104681538 (TSC2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
104681538 (TSC2)
09143 Cell growth and death
04115 p53 signaling pathway
104681538 (TSC2)
04218 Cellular senescence
104681538 (TSC2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
104681538 (TSC2)
04919 Thyroid hormone signaling pathway
104681538 (TSC2)
09149 Aging
04211 Longevity regulating pathway
104681538 (TSC2)
09159 Environmental adaptation
04714 Thermogenesis
104681538 (TSC2)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
104681538 (TSC2)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
104681538 (TSC2)
05163 Human cytomegalovirus infection
104681538 (TSC2)
05165 Human papillomavirus infection
104681538 (TSC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
rro01009
]
104681538 (TSC2)
Protein phosphatases and associated proteins [BR:
rro01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
104681538 (TSC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tuberin
DUF3384
Rap_GAP
Cnd1
Motif
Other DBs
NCBI-GeneID:
104681538
NCBI-ProteinID:
XP_010386162
UniProt:
A0A2K6RHU4
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All DBs
Position
20:complement(71124712..71166995)
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AA seq
1898 aa
AA seq
DB search
MPDCCGLHIPAAHAAPSRDARITGLSSRELPRTTTPSKPRGGPSRDAAAGSAGRASGSVQ
GPAGVRLSPRPGGPARGGASREGFSGASWPTMAKPTSKDSGLKEKFRILFGLGTPRPNPR
SAEGKQTEFIITAEILRELSVECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLL
QPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLDVFKALTDN
GRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRT
ASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLG
HSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMAC
PNEVVSYEIVLSITRLIKKYRKELQVVTWDILLNIIERLLQQLQTLDSPELKTIVHDLLT
TVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALM
ERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLAT
QLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLV
ILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRL
GLPNKDGVVRFSPYCVCDYMEPERGSEKKAGGPLSPPTGPPGPAPAGPAVRLGFLPYSLL
FRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLER
LRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALS
ICSVEMPDIMIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPQLYRNFAAEQYASVF
AISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPE
KDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRS
RIQTSLTSASLGSADENSMAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGE
FLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPELSSSPGMNVRQTKEAP
AKLESQAGQQVSCGARDRVRSMSGGHGLRVGALDVPASQFPGSATSPGPQTAPAAKPEKA
SAGTRLPMQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQ
ELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHR
SVSWADSAVVMEEGSPGEVPVPVEPPGLEDFEAVLGVDRRTDAYSRSSSTSSQEEKSFHA
EELVAGGIPIERAVSSEGGRPSVDLSFQPSQPLSKSSSSPELQSLQDILGDPGDKADVGR
LSPEVKARSQSGILDGEGAAWPASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPS
RRGRRVERDAFKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFER
SVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQP
DKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIV
YNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLP
FVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVH
PPSHTKGPAQTPAEPTSGYEMGQRKRLISSVEDFTEFV
NT seq
5697 nt
NT seq
+upstream
nt +downstream
nt
atgccggactgctgcggactacacatcccggcggcccatgcggccccgtcacgtgacgca
aggatcaccggcctttcctctagagagctgcccagaactacaactcccagcaagccccgc
ggcggcccttcgcgcgacgccgctgccggaagtgcgggtcgcgcttccggcagcgtccag
gggccagcgggggtgcgcctttccccgcgtcctggcggcccggcgcgcggtggcgcgtcg
agggaggggttttctggtgcgtcctggcccaccatggccaaaccaacaagcaaagattca
ggcttgaaggagaagtttaggattctgtttggactgggaacaccgaggccaaatcccagg
tctgcggagggcaaacagacggaatttatcatcaccgcggaaatcctgagagaactgagt
gtggaatgtggcctcaataatcgcatccggatgatagggcagatttgtgaagtcgcaaaa
accaagaaatttgaagagcacgcagtggaagcactctggaaggcggtcgcggatctgctg
cagccagaacggccgctggaggcccggcacgcggtgctggctctgctgaaggccatcgtt
caggggcagggcgagcgtttgggggtcctcagagccctcttctttaaggtcatcaaggat
tacccttccaacgaagacctccacgaaaggctggatgttttcaaggccctcacagacaat
gggagacacatcacctacttggaggaagagctagcggactttgtcctgcagtggatggat
gtcggcttgtcctcggaattccttctggtgctggtgaacttggtcaaattcaacagctgc
tacctcgatgagtacatcgcaaggatggttcagatgatctgcctgctctgcgtccggact
gcgtcctctgtggacatagaggtctccctgcaggtgctggacgccgtggtctgctacaac
tgcctgccggctgagagcctcccgctgttcatcgtcaccctctgccgcaccatcaacgtc
aaggagctctgcgagccttgctggaagctgatgcggaacctccttggcacccacctgggc
cacagtgccatctacaacatgtgccacctcatggaggacagagcctacatggaggacgcg
cccctgctgagaggagccgtgttttttgtgggcatggctctctggggagcccaccggctc
tattctctcaggaactcaccgacatcggtgctgccatcattttaccaggccatggcatgt
ccgaacgaggtggtgtcctatgagatcgtcctgtccatcaccaggctcatcaagaagtat
aggaaggagctccaggtggtgacgtgggacattctgctgaacatcatcgaacggctcctt
cagcagctccagaccttggacagcccggagctcaagaccatcgtccatgacctgctgacc
acggtggaggagctgtgtgaccagaatgagttccacgggtctcaggagagatactttgaa
ctggtggagagatgtgcagaccagagacctgagtcctccctcctgaacctgatctcctat
agagcacagtccattcacccggccaaggacggctggattcagaacctgcaggcgctgatg
gagagattcttcaggagcgagtcccgaggtgccgtacgcatcaaggtcctggatgtgctg
tcctttgtgctgctcatcaacaggcagttctacgaggaggagctgattaactcagtggtc
atctctcagctctcccacatccccgaggataaagaccaccaggtccgaaagctggccacc
cagttgctagtggacctggcagagggctgccacacacaccacttcaacagcctgctggac
atcatcgagaaggtgatggcccgctccctctccccacccccagagctggaagaaagggat
gtggccgcgtactcggcctccttggaggatgtgaagacagctgtcctggggcttctggtc
atccttcagaccaagctgtacaccctgcctgcgagccatgccacgcgcgtttatgagatg
ctggtcagccacattcagctacactacaagcacagctacaccctgccaatcgccagcagc
atccggctgcaggcctttgacttcctgttgctgctgcgggccgactcactgcaccgcctc
ggcctgcccaacaaggatggggtcgtgcggttcagcccctactgcgtctgcgactacatg
gagccagagagaggctctgagaagaaggccggcggccccctttctcctcccacagggcca
cctggcccggcgcctgcaggcccggccgtgcggctgggcttcctgccctactccctgctc
ttccgcgtcctgctgcagtgcttgaagcaggagtctgactggaaggtgctgaagctggtt
ctgggcaggctgcctgagtccctgcgctacaaagtactcatctttacctccccttgcagt
gtggaccagctatgctctgctctctgctccatgctttcaggcccaaagacactggagcgg
ctccgaggcgccccggaaggcttctccagaactgacctgcacctggctgtggttccagtg
ctgacagcattaatctcttaccataactacctggacaaaaccaaacagcgcgagatggtc
tactgcctggagcagggcctcatccaccgctgtgccagccagtgcgtcgtcgccttgtcc
atctgcagcgtggagatgcctgacatcatgatcaaggcgctgcccgtcctggtggtgaag
ctcacgcacatctcggccacagccagcatggccgtcccgctgctggagttcctgtccact
ctggccaggctgccgcagctctacaggaactttgccgcggagcagtatgccagtgtgttc
gccatctcgctgccgtacaccaacccctccaagtttaatcagtacatcgtgtgtctggcc
catcacgtcatagccatgtggtttatcaggtgccgcctgcccttccggaaggattttgtc
cctttcatcactaagggcctgcggtccaatgtcctcttgtcttttgatgacacccccgag
aaggacagcttcagggcccggagtactagtctcaacgagaggcccaagagtctgaggata
gccagaccccccaaacaaggcttgaataactctccacccgtgaaagaattcaaggagagc
tctgcagccgaggccttccggtgccgcagcatcagtgtgtctgaacatgtggtccgcagc
aggatacagacgtccctcaccagtgccagcctggggtctgcagacgagaactccatggcc
caggctgacgatagcctgaaaaacctccatctggagctcacggaaacctgtctggacatg
atggctcgatacgtcttctccaacttcacagctgtcccgaagaggtctcctgtgggcgag
ttcctcctggcgggtggcaggaccaaaacctggctggttgggaacaagcttgtcaccgtg
acgacgagtgtgggaaccgggacccggtcgttactaggcctggactcgggggagctgcag
tccggcccggagttgagctccagccctggcatgaatgtgagacagacgaaggaggcgcca
gccaagctggagtcccaggctgggcagcaggtgtcctgtggggcccgggaccgggtccgt
tctatgtcagggggccatggtcttcgagttggcgccctggatgtgccagcctcccagttc
ccgggcagtgccacttctccaggaccacagactgcaccagccgcgaagcctgagaaagcc
tcagccggcacccggcttcctatgcaggagaagacgaacctggcagcctacgtgcccctg
ctgacccagggctgggcggagatcctggtccggaggcccacagggaacaccagctggctg
atgagcctggagaacccgctcagccccttctcctcggacatcaacaacatgcccctgcag
gagctgtccaacgccctcatggcagcggagcgcttcaaggagcaccgggacacagccctg
tacaagtcgctgtcggtgccagcggccagcacggccaaaccccctcctctgcctcgctcc
aacacagtggcctctttctcctccctgtaccagtccagctgccaaggacagctgcacagg
agcgtttcctgggcagactccgccgtggtcatggaggagggaagtcctggcgaggttcct
gtgccagtggagcccccaggattggaggactttgaggcagtgctaggcgtggacaggcgc
acagacgcctacagcaggtcgtcctcaacctccagccaggaggagaagtcattccacgca
gaggagctggttgccgggggaatccccattgaacgagccgtctcctcggagggtggccgg
ccctctgtggacctctccttccagccctcgcagcccctgagcaagtccagctcctctcct
gagctgcagagcctgcaggacatcctcggggaccctggggacaaggccgacgtgggccgg
ctgagccctgaggttaaggcccgttcacagtcaggaatcctggacggggaaggtgctgcc
tggccagcctcgggcgaagacagtcggggccagcccgagggtcccttgccttccagctcc
ccccgctcgcccagtggcctccggccccgcggttacaccatctctgactcggccccatca
cgcaggggcaggagggtagaaagggatgcctttaagagcagagccacagcttccaatgca
gagaaagtgccgggcatcaaccccagtttcgtgttcctgcagctctaccattcacctttc
tttggtgacgagtcaaacaagccaatcctgctgcccaatgagtcacagtcctttgagcgg
tcggtgcagctcctcgaccagatcccatcatacgacacccacaagatcgccgtcctgtat
gtgggagaaggccagagcaacagtgagctcgccatcctgtccaacgagcatggctcctac
aggtacacggagttcctgacgggcctgggccggctcatcgagctcaaggactgccagcca
gacaaggtgtacctgggaggcctggacgtgtgtggtgaggacggccagttcacctactgc
tggcacgacgacatcatgcaagccgtcttccacatcgccaccctgatgcccaccaaggac
gtggacaagcatcgctgtgacaagaagcgccatctgggcaacgatttcgtgtccattgtc
tacaatgactctggcgaggacttcaagctcggcaccatcaagggccagttcaactttgtc
cacgtgatcatcaccccgctggactatgagtgcaacctggtgtccctgcagtgcaggaaa
gacatggagggccttgtagacaccagcgtggccaagatcgtgtctgaccgcaacctgcct
tttgtggcccgtcagatggccctgcatgcaaacatggcctcacaggtgcaccacagccgc
tccaaccccactgacatctacccctccaagtggattgcccggctccgccacatcaagagg
ctccgccagcggatctgcgaggaagccgcctactccaaccccagcctgcctctggtgcac
cccccgtcccataccaaaggccctgcacagactccggccgagcccacgtctggctacgag
atgggccagcggaaacgcctcatctcctccgtggaggatttcaccgagttcgtgtga
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