Rhodococcus ruber: CS378_08745
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Entry
CS378_08745 CDS
T05142
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rrz
Rhodococcus ruber
Pathway
rrz00860
Porphyrin metabolism
rrz01100
Metabolic pathways
rrz01110
Biosynthesis of secondary metabolites
rrz01120
Microbial metabolism in diverse environments
rrz01240
Biosynthesis of cofactors
Module
rrz_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
rrz_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
rrz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CS378_08745
Enzymes [BR:
rrz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CS378_08745
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CS378_08745
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ATQ28804
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Position
complement(1965897..1967462)
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AA seq
521 aa
AA seq
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MSRVRKHNPGRILFVGAGPGDPALLTVRARDVLAGATIAFTDPDVDRGVVALVGTTAGRD
AETGEPVAEVRPALGEPTEVAKTLVAEAKNGHDVVRLVAGDPLTTDSVIAEVNAVARTQV
VFEVLPGLTPGSAVPSYAGMALGSCHTEVDVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVEHGLAPQTPAAITVRGTTRQQRTVEATLATLNDAGSELVGPLVVTVGKIVSQRGKL
SWWESRALYGWTVLVPRTKEQAGEMSERLVTHGAIPIEVPTIAVEPPRSPAQMERAVKGL
VDGRYQWVVFTSTNAVRAVWEKFEAFGLDARAFSGVKIACVGQATADKVRSFGITPELVP
SGEQSSEGLLAEFAPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAETREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEFGLR
VDVQPETAQIGPLVEALAEHAARLRAEGALPPPRKKSRARR
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagtccgtaagcacaatcccggacggatcctgttcgtgggagctgggccgggc
gacccggctctgctgaccgtgcgtgcccgcgacgtgctcgcgggcgcgacgatcgccttc
accgaccccgacgtcgacaggggggtggtggcgctcgtcggcaccaccgccggccgggac
gcggagaccggggagcccgtcgccgaggtgcgtcccgcgctgggcgagcccaccgaggtc
gccaaaaccctcgtcgcggaggcgaagaacggccacgatgtcgtgcgcctcgtcgccggc
gacccgctgaccaccgactcggtgatcgccgaggtcaacgccgtcgcccgcacccaggtg
gtgttcgaggtcctgccggggctgacccccggctcggccgtgccgagctacgccggcatg
gcgctgggctcgtgccacaccgaggtcgacgtgcgcggcgaggtggactgggcggcgctc
gccgccgcgcccggcccgctggtgctgcacgccacgtccggtcatctcgcggagactgcg
agcgccctcgtcgagcacgggctcgcgccgcagaccccggcggcgatcaccgtccgtggc
acgacccggcagcagcgcacagtcgaagccaccctcgccacgctcaacgacgccggttcc
gagctcgtcggtccgctcgtcgtcaccgtcggcaagatcgtctcgcagcgcggcaaactc
tcgtggtgggagtcccgcgccctgtacgggtggacggtgctggtgccgcgcaccaaggag
caggccggggagatgagcgagcggctcgtcacgcacggagcgatcccgatcgaggtgccg
accatcgcggtggagccgccccgcagtccggcccagatggagcgggccgtcaagggactc
gtggacggccgctaccagtgggtggtgttcacctccacgaacgcggtgcgcgcggtgtgg
gagaagttcgaggcgttcggcctcgacgctcgcgccttctcgggtgtgaagatcgcgtgt
gtcgggcaggcgaccgcggacaaggtgcgctcgttcgggatcacccccgagctggtgccc
tcgggcgaacagtccagcgaggggctgctggccgaattcgccccgtacgacgacgttttc
gatcccgtcaaccgggtgctgctgccgcgcgccgacatcgccaccgagaccctcgcggag
ggcctgcgcgagcggggctgggagatcgacgacgtgactgcctaccgcacggtgcgggcg
gcaccgccgccggccgagacccgcgagatgatcaagaccggtgggttcgacgcggtgtgc
ttcacctcgtcgtcgacggtccgcaacctcgtgggtatcgcgggtaagccgcacgcgcgc
accatcgtcgcgtgcatcgggccgaagaccgcggagaccgcgatcgagttcgggctgcgg
gtggacgtgcagccggagaccgcgcagatcggtcccctggtggaggcgctcgccgagcac
gccgcccggctgcgggccgagggcgcattgccgccgccccgcaagaagtcccgcgcccgc
cgctga
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