Rhipicephalus sanguineus (brown dog tick): 119374038
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Entry
119374038 CDS
T07382
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
rsan
Rhipicephalus sanguineus (brown dog tick)
Pathway
rsan00280
Valine, leucine and isoleucine degradation
rsan00640
Propanoate metabolism
rsan00785
Lipoic acid metabolism
rsan01100
Metabolic pathways
rsan01210
2-Oxocarboxylic acid metabolism
Module
rsan_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rsan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
119374038
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
119374038
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119374038
Enzymes [BR:
rsan01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
119374038
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
RusA
TPP_enzyme_M
Motif
Other DBs
NCBI-GeneID:
119374038
NCBI-ProteinID:
XP_037500025
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Position
11:complement(34854857..34882324)
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AA seq
449 aa
AA seq
DB search
MAARTTARILCALSQTGRRNPHRRLYRTSAICGQQRGSSSSVPPLDDTSRPQYLGTKCDW
TESIEFRTHVVSEGFPVYRVLNRDGKPIVPSEDPQLSEQVLLKMYNGMTLLNSMDRILYE
SQRQGRISFYMTNFGEEGTHFGSAAALDNNDLIYGQYREAGVLVWRDYPLAQFMGQCYGN
ELDDCKGRGMPVHYGSDKHNFVTISSPLATQMPQAVGSAYAFKLAQKKNCVVCYFGEGAA
SEGDAHAALNFAATLDCPVIFFCRNNGYAISTPAHEQYKGDGIVARGPGYGIASIRVDGN
DVLAVYNVTKAARQIAVEECKPVLIEAMTYRIGHHSTSDDSSAYRSVDEVRSWDRNDHPI
TRFRNYLVHRGIWDDAKEEQWKNETKKQIMQAFARAEKLKKPPVKYMFTDVYRQMPDSLQ
EQWELMRQHLQQYKEHYPLSSFKELPDGE
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atggcagccaggacaacggcgcgaattctctgcgctctctcgcaaacggggaggcgaaat
ccgcaccgtcgactataccgcacatcggcgatctgcgggcaacagcggggcagcagctcc
tcagtcccaccgctggatgacaccagccgaccgcagtacctgggtaccaagtgcgactgg
accgagagcatcgagttccgcacgcacgttgtctccgaagggttcccagtctaccgtgtc
ctcaaccgcgatgggaagcctattgtgccctctgaggatcctcagctgtcggagcaggtg
ctgctcaagatgtacaatggcatgacgctgctgaacagcatggaccgaatcctgtacgag
tcacaaaggcaagggcgcatctctttctacatgaccaactttggcgaggagggcacacac
tttggcagcgctgctgcactggacaacaatgacctcatctacggacagtaccgagaagca
ggagtgctggtgtggcgggactacccactggctcaattcatgggccagtgctacggcaac
gagctggacgactgcaagggacgaggcatgcccgtgcactatggcagcgacaagcacaac
ttcgtcaccatcagctcaccgctcgccacacagatgccccaggctgtgggctctgcatac
gcgttcaagctcgctcaaaagaagaactgcgtcgtctgctactttggcgagggtgccgcc
agtgaaggcgacgcccatgctgccctcaattttgccgccactcttgactgtccggtcatc
ttcttttgccgaaataatggctacgccatttcaaccccagcccatgaacagtacaaaggt
gatggaatcgttgcaagaggtcctggctatggcatcgcatcgatacgtgttgacggcaac
gatgtcctggctgtgtacaatgtcacaaaagctgctcgccaaatcgcagttgaggaatgc
aaaccagtgctcatagaggccatgacctacagaatcggtcatcacagcacatcagatgac
agctcagcataccggtctgtggacgaggttcggtcctgggaccggaacgaccaccccatc
acccgcttccggaactacctcgtccaccgtggaatctgggacgacgccaaggaggaacag
tggaagaacgagaccaagaagcagatcatgcaggcatttgcacgtgctgagaaactgaag
aagccgccagtgaagtacatgttcacggacgtctacagacaaatgcccgattcactgcag
gagcagtgggaactaatgaggcagcatctgcagcagtataaggagcactatccactcagc
tccttcaaagagcttcccgacggtgaatag
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