Runella slithyformis: Runsl_2240
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Entry
Runsl_2240 CDS
T01553
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rsi
Runella slithyformis
Pathway
rsi00300
Lysine biosynthesis
rsi00550
Peptidoglycan biosynthesis
rsi01100
Metabolic pathways
rsi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rsi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Runsl_2240
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Runsl_2240
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Runsl_2240
Enzymes [BR:
rsi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Runsl_2240
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
ACCA_BT
Motif
Other DBs
NCBI-ProteinID:
AEI48652
UniProt:
A0A7U3ZK64
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All DBs
Position
2579632..2580924
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AA seq
430 aa
AA seq
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MQGITIPELYDLFLTCTGVSTDTRQITEGCLFVALRGDKFDGNLYAKDALEKGAKYAIVD
NSDVAVDNRYLWVENSLESLQQLAAYHRKQLNIPVIGLTGSNGKTTTKELIAAVLSKKFK
TYATKGNLNNHIGVPLTLLAIDDTYEIAVVEMGANHQKEIALLSGISEPTHGLITNVGKA
HLEGFGGIEGVRIGKGELYDWLAHSGGTVFINGSDTALVEMADRRTFAEEVTYLAGDDAP
VLLEDSPLVVYRDAEGNQINTCLTGKYNFENIAVALAIGRYFGVSNALANQAVAEYNPTN
NRSQIIQKGTNTVIMDAYNANPSSMSAAIENFGRLKAKRKMVILGDMLELGDDSPEEHLL
IGKLIAQQHFDVVILAGKLMQEALPALPQAYYFPDKFSLHNWIVDHPQQNTHVLIKGSRG
MGLETVVPYL
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
atgcaaggaataacgatccctgaactttacgatttgtttctcacctgtacgggtgtttcg
accgacacccgtcaaatcacggaaggatgtttgttcgtggcacttcgcggcgataagttt
gatggtaatctatacgccaaagacgcgctggaaaagggagcaaagtacgcgattgtggat
aactccgacgtagcggtggataaccgatacctgtgggtggaaaacagcctcgaatccttg
cagcaattagccgcctatcaccgaaagcagttgaatatccccgttattggccttaccggt
tccaacggaaaaaccacgaccaaagagttgattgcggctgtattgtccaaaaaattcaaa
acgtatgccactaaaggtaatctgaataatcacatcggggttccgcttacactattggca
atagatgatacctacgaaatagccgtggtggaaatgggggccaatcaccaaaaggaaatt
gcgttgctcagcggtatttctgagccaacgcatgggttaattacgaacgtggggaaagct
catctggagggttttggcggcatcgaaggcgtcaggattggtaaaggagaactctacgat
tggctggcccactccggaggaacggtatttatcaacggttccgataccgccttggtggaa
atggccgatcggcgcacttttgccgaagaagttacctatttggcaggagatgacgctccg
gtactgctggaagactcgccgttggtagtgtatcgggacgccgaaggcaaccaaataaat
acctgcctgacgggaaagtataactttgaaaacatcgcggtggcgctcgccatcggtcgg
tattttggcgtttccaatgcactggccaatcaagccgttgccgagtacaatcccaccaat
aaccgttctcaaatcattcaaaaaggcaccaataccgtcatcatggatgcctataacgcc
aatccgtcgtcgatgtcggcggcgattgaaaacttcgggcgactgaaagcgaagcgaaag
atggtcattttgggcgatatgctcgaactcggcgatgactcacccgaagaacatttgctg
ataggaaaattgatcgcccagcaacattttgacgtggtcattctggcgggaaaactcatg
caggaggctctgccggcgttgcctcaagcctattattttccggataagttttcattgcat
aattggatcgtagaccacccgcagcaaaatacgcatgtcctcatcaaaggctcacggggc
atggggctcgaaacggtggtgccgtatctctga
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