Ralstonia solanacearum CMR15: CMR15_mp10292
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Entry
CMR15_mp10292 CDS
T02725
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase 2 (Alpha-isopropylmalate synthase 2) (Alpha-IPM synthetase 2)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
rsm
Ralstonia solanacearum CMR15
Pathway
rsm00290
Valine, leucine and isoleucine biosynthesis
rsm00620
Pyruvate metabolism
rsm01100
Metabolic pathways
rsm01110
Biosynthesis of secondary metabolites
rsm01210
2-Oxocarboxylic acid metabolism
rsm01230
Biosynthesis of amino acids
Module
rsm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rsm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CMR15_mp10292 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CMR15_mp10292 (leuA)
Enzymes [BR:
rsm01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CMR15_mp10292 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CBJ39945
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All DBs
Position
CMR15_mp:complement(348880..350610)
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AA seq
576 aa
AA seq
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MLKHPATKYRPFPPIALPDRTWPSKTITHAPIWMSTDLRDGNQALFEPMNAERKMRMFKM
LVQIGFKEIEAAFPAASQTDYDFVRELIEGGHIPEDVTIEVLTQAREDLIRRTMESLRGA
RRAIIHVYNATSPVFRRTVFNTDREGVKRIAVESAKLIREIAESMPETQWTYQYSPEVFS
GTELEFALEVCNAVTEAWDPTPAHKIIFNLPATVEMATPNVYADQIEWMHRHLARRDSIL
LSVHPHNDRGTAVAAAELAVMAGADRVEGCLFGNGERTGNVDLVTLALNLYSQGIDPGLD
FSHVNDVARTCEDCTQLPVHPRHPYVGDLVFTAFSGSHQDAIKKGFAVQKPDAIWEMPYL
PIDPADVGRTYDSIIRVNSQSGKGGIAYLLESGYGIAMPRRLQVEFSSTVQQLTDASGRE
ATAADIWALFQETYLRADGPIGYVSHRLTERDDGSQHIRLVVNIADREHVCEGVGNGPLD
ALVQALGAVLAAPVSIHHYEERALGQGANADAIAFAELAAPGVAGSVFGVGIDANLTTAS
IRAVVGGVNRLAARHAQAQPGQSLLRRGTAPSMELA
NT seq
1731 nt
NT seq
+upstream
nt +downstream
nt
atgttgaagcaccccgccaccaagtaccgcccgttcccgccgatcgccctgcccgatcgc
acctggccgtccaagaccatcacccatgcgccgatctggatgagcacggacctgcgcgac
ggcaaccaggccctgttcgagccgatgaacgccgagcgcaagatgcgcatgttcaagatg
ctcgtgcagatcggcttcaaggaaatcgaagccgccttccccgccgcctcccagaccgac
tacgacttcgtgcgcgagctgatcgaaggcggacatatccccgaggacgtgaccatcgag
gtgctgacacaggcgcgcgaggacctgatccgccgcaccatggaatcgctgcgcggcgcc
cggcgcgcgatcatccacgtctacaacgcgacctcgccggtgttccgccgcacggtgttc
aacaccgaccgcgaaggcgtcaagcgcatcgccgtagagagcgcgaagctgatccgcgag
atcgccgagtcgatgcccgagacgcagtggacgtatcaatacagcccggaggtcttcagc
ggcaccgagctggagtttgcgctggaggtctgcaacgccgtcaccgaggcgtgggacccg
acgcccgcgcacaaaatcatcttcaacctgccggccacggtggagatggccacgcccaac
gtctacgccgaccagatcgaatggatgcaccgccacctggcgcgacgcgattcgatcctt
ctctccgtgcacccgcacaacgaccgcggcacggcggtcgcggcggccgagctggcggtg
atggccggcgccgaccgcgtggaaggctgcctgttcggcaacggcgagcgcaccggcaac
gtggacctggtcacgctggcgctcaacctgtattcgcagggcatcgatccggggctggac
ttctcgcacgtcaacgacgtggcgcgcacgtgcgaagactgcacgcagctgccggtgcat
ccgcgccatccgtacgtgggcgacctggtcttcaccgcgttctcgggctcgcaccaggac
gccatcaagaaaggctttgcggtgcagaagccggatgccatctgggagatgccctatctg
ccgatcgacccggccgacgtgggccgcacctacgattcgatcattcgcgtcaacagccag
tcgggcaagggcggcatcgcttatctgctggaaagcggctatggcatcgcgatgccgcgc
cggctgcaggtggagttcagcagcaccgtgcagcagttgaccgacgccagcggccgcgaa
gccaccgccgccgacatctgggcgctgttccaggagacctatctgcgggccgacgggccg
atcggctacgtgtcgcaccggctcaccgagcgtgacgacggcagccagcacatccgcctg
gtcgtcaacatcgccgaccgcgagcacgtctgcgaaggcgtgggcaacggaccgctggat
gcgctggtgcaggcgctgggcgcggtgctggcggcgccggtgtcgatccaccactacgaa
gagcgcgcactgggccagggcgcgaacgccgatgccatcgcctttgctgaactggccgcg
ccgggcgtggccggcagcgtgttcggcgtgggcatcgacgcgaacctgacgaccgcgtcg
atccgcgcggtggtgggcggcgtgaaccggctggcggcgcgccacgcgcaggcgcagccg
ggtcaaagcctgctgcggcgcggcacggcaccttccatggagcttgcctga
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