Rana temporaria (common frog): 120929172
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Entry
120929172 CDS
T07929
Symbol
BRCA2
Name
(RefSeq) breast cancer type 2 susceptibility protein isoform X1
KO
K08775
breast cancer 2 susceptibility protein
Organism
rtem
Rana temporaria (common frog)
Pathway
rtem03440
Homologous recombination
rtem03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
rtem00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
120929172 (BRCA2)
03460 Fanconi anemia pathway
120929172 (BRCA2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
rtem04121
]
120929172 (BRCA2)
03036 Chromosome and associated proteins [BR:
rtem03036
]
120929172 (BRCA2)
03400 DNA repair and recombination proteins [BR:
rtem03400
]
120929172 (BRCA2)
Ubiquitin system [BR:
rtem04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
120929172 (BRCA2)
Chromosome and associated proteins [BR:
rtem03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
120929172 (BRCA2)
DNA repair and recombination proteins [BR:
rtem03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
120929172 (BRCA2)
FA (Fanconi anemia) pathway
Downstream FA components
120929172 (BRCA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB3
BRCA-2_OB1
BRCA2DBD_OB2
BRCA2_TR2
Tower
DUF6429
Motif
Other DBs
NCBI-GeneID:
120929172
NCBI-ProteinID:
XP_040196373
LinkDB
All DBs
Position
2:complement(78682269..78768688)
Genome browser
AA seq
3074 aa
AA seq
DB search
MAAVQLGGSVFLHLLRAHCPASDLGPISVNWFEELTAEAVQRQSRLCVDEEKGVEGLDDS
LFKTPKRKRPIDSQLDSTPIIFKEQSLCSPLFLSPTRDFPKNQPSAKNVSKTEKSPGDAT
QCLRDEVFGTSKQCHNSPSVMGEMFKTPLWDKKYTYRTPQRDWKNDVFDSLCCTPKFIGN
TTSRCISESLGAEADPEMSWSSSLATPPSPTVIIAQANDETSKIRPFDNKDAVIVQSLFS
KLCNDAETSFMAGPTDPKVDKDFQMKADDHLADSAYAVPNEAARGAFESSESGEVQKNVL
KNKDACQKTENVLEGMEDILSIFFTREKPPGLRKVKVDNRAKRRKKNDSNGVQESAVGQS
IFSLEAFLNMESQNKCNKPELENTHVANFHPSSMPSSYEWSPIALPDLNTTQGDVHLPVQ
TDVIYGGGKELGPSITNYSPTRNSGKSSSYHTPAGSCKVANGLEMAIPITVQQTLPDTKP
DVDTTCSAQNTRPTEGTTSADLELSAQQVLVEINEKRPQIGSTNIKATLSILKRQPKFLY
CLNDGKNGQDGRTRDIGKVSHNEPIRIPEKHAGFGEVQKELDSVNAACTHIQQDAQLEPK
EDSEYLKEDALDVQEIEENLLNLKHVDKPISKQAPRLDTATDISTTINIQADVKGTEHRN
TGDASKKSLLESVSISKKNSIDKNVGHSDVTLAKKQVMENDHSSDVTKDHKEQLDSHEEC
AFSTTEHHNASTDSLPLDVSLCIRKVENFGGFKTGSNKLISISEENLRKGELLFKDDDPI
HHISHPLPPAVDINNTLDIADSASVFNGFRTASRKEIKVDECKIAKGMLLFKDLEDGMCD
NIITNKDLRTPAANLVPENEKAREPDNNFEPLNKLSTEETKDSRTSNLLRLNNHSSKEVQ
IKGMRSQNVLLLQHSKSSTSDGKSQKETSLSSEIQSRFCEILTESQKAEVSELSSILENA
DSQFDFTQFRKTGTVTSNNNQNLRSAEDGIGESENLNNSDVWNDVDFNDSFATGAEHVEN
KDSSVKLSLEKKDNSVGATAYDSGVASVSEKLVSKDKKKKFGGFSLASGKCINITDDDMV
KAFELFCDLDDTTLSVKHPSTDVNKGNFPTTSAVPSTPNVQQVSKDSITVPRNVKESSIV
YSKTESSTKCEKRSSTFNEYMFNREKHNSKMKLMNEFVDSGNEVSGSEEAFCVQNINTAS
CGSLASASCVSTMPVGFSTGKGKVISVDKAALAKAKSIFNDLLHPDDIDRNQGSTSGVVV
KENINTISHGEPGKRTHELTVEQSAVGFITSGTGAPIPHDSVQKEKTIFDKVSGSELAHC
ISLPKEDTLNTKRVEFSTAHGKSVHLSEESLRRAQEIFADIDDHHLVTVGENSKFSLCDV
EKISSRSPNTNNVQDVLSKTLQEKEPVLPLLGFSTASGKSVVVSCDSLQKAKMMFAETDL
AVHNGLEGIEYQQMHDRPRSNPAEIKLSKPNIRGCNVATKNTTQVIVNVPPPLGFSTASG
KTVAVSNESLQKARRMLSDTDNSGLENGFQSSQTGLEIGNQEKCRDLVLCSSENTKLSKV
RLAEGNPMKPFLRDGTTDSCLEKTDLPPIVKTSRVAQPRDMHLPQETAPNIVKPSFITAG
GKPLQMSENALKKACEMFAEIDGQLENSCSLKQSVERNTKWNTPESSNVQDPASPTVSKE
TILALPAPGFSTASGKNVAVSADALLKARILLADGEDGITDESIAQGKSKAISVKNREEN
EMTLKPSTFHSGTKELMSLSKTSRGMYPFSEDHMPEKASKMLVNNSFMPGMPCFSTASGK
TVTLSEEALKKAQQIFSEMENCPSQQDKLEDVLGDNPLRVSKVQTSLHQKPKEQTTLETS
ETSNLPKTTTNRFGFSTASGKQVSVSETAIQTVKDLFQEFTESENLQEHCPNGKGDSNSS
KTANTLTPLVNKADVIANFNDELVELQNHRARTRENINIGRPSIASSCDSQRPMLRHSTP
FHNTRVPSKRNTVSSMTSRTPENYFEIEAAESAKAFMDDEDLTDGIMKADATNKLLILRN
GKRLRSDDRTSHGEPPIKRQLLPEFDRSLMQESKLALKPLTSSPHSDFKDRRKFVYNVSL
KASFCDPMSFSAGNKEAQKSQLITRSAAFRHSSSDISADASDDGRQLKDIPSYKPATGTS
EEWTSDQDDLEPHNSADVSQLLASLHCARDLQEMRVRKKQRQNIKPYSGSLYGLKATSTD
RITLISAVQGKLPTMYPKEQLYRFGVLKNHIGIDSETAKIFDFHCLDYFTKSCLSGGGVQ
IADGGWLIPSDKLTAGREEFYRALCDTTGVDPKLISSEWVYNHYRWIVWKLAAMEVMFPE
QFAGRCLTPERVLLQLKYRYEVEIDKSRRSALKRIMERDDTAAKTLVLCVSKVISWGGND
KSESKDTKQGPAVIEVTDGWYGIKALLDTSLTALLHRRRLFVGQKIIIHGAELVGSEEAC
TPLEAPESLMLKLAANSTRPARWYTKLGYFCDPRPFCVPLSSLLAEGGIVGCVDIVIQRI
YPIQWMEKMANGTYVFRNDRAEKREAERHSLKQQKNLEVLFLKIQQEFEQQEACESKAKG
TKRNSLSVTQIAALQDGAEIYEALQNEPDPGYLESCMSSEQLRVLNHYRQVINDKKQALI
QTEFRKAIESTEQGSEGCTRREVTPVWKVRIVDYKEQDPTSAYILNIWRPLPDLVSLLKE
GCHFKIYQLATSHPKCKADTAAVQLTATKKTQFQQLQSSQDILEQIYTERQVTDFSQLME
PNFKTEYGEVDIVGLVISIHQKIGAAPIVYLSDEAHDIVAVKFWIDLSQLSLEELAKPGT
LIAASNLRWRSESTAGIPIVSFGDLSYITANPKETHLQKAIHKLRQSVQATQKFHHEAEI
QLFNILRVPHPEEKPPPAQHSSDSYAATTKFSTPAGKLGSAQMNPLNTPSRSNTVIISGS
DMDPKTCKKIKGLDLLSRIPSPPPITPVRPSVTPSLQRAFRPPRSMQKDVQTSEQPILSK
GEFVDDEELAMINTQALVSGLEKRKIQQKIEMSAEKTEKISPDQSDGKPDPSGNDTKKED
TGHGKLHKRRRHKL
NT seq
9225 nt
NT seq
+upstream
nt +downstream
nt
atggctgctgtacagctggggggctccgtcttcctgcacctcctccgtgctcactgtccg
gcctcagatctaggtcctatcagtgtgaactggtttgaggagctcactgcagaagctgta
cagaggcagtccaggctgtgtgtagatgaagagaagggagtggaaggactggatgacagc
ctttttaagaccccaaaacgcaaacgaccaatcgacagccagcttgactctacaccaatc
atatttaaagaacaaagcctttgttcaccccttttcctttcaccaaccagggattttcct
aaaaatcaaccttcggcaaaaaatgtcagtaaaacagaaaaaagtcccggagatgcaacg
cagtgtcttcgcgatgaagtctttggtacctcaaagcagtgtcataacagtcctagtgtt
atgggggagatgtttaagactccactttgggataaaaagtacacctacagaacaccccag
cgggattggaaaaatgatgtgtttgatagcctgtgttgcacaccaaaatttattgggaac
acaacctcaaggtgtatatcagaaagtcttggtgcagaagcagaccctgagatgtcttgg
tcaagctctttagcaacaccaccctctccaacagtgataattgctcaagctaatgatgaa
acttctaaaataaggccctttgataataaagatgcggtgattgtgcagagcctattttct
aagctttgtaatgatgcagaaacatcttttatggctggaccaactgaccccaaggttgac
aaggacttccaaatgaaggctgatgaccacttggctgattcagcttatgctgttcctaat
gaagcagccaggggtgcatttgaatcttctgagtctggggaggtgcaaaagaacgttcta
aagaataaagatgcttgtcagaagactgagaatgttcttgaggggatggaagacatcttg
tccatattttttactcgtgagaaacctccaggactgagaaaagtgaaggttgataatcga
gccaaaagaagaaaaaaaaatgatagtaatggggttcaggaatctgctgttggccagagt
atattttccttggaggcattccttaatatggagagccagaataaatgcaacaaacctgaa
ctggaaaacacgcatgttgcgaattttcatccctcttctatgccgtcttcatatgaatgg
tctccaatagccctgcctgatctaaataccacacagggagatgtgcacttgccagttcaa
acagatgtgatttatgggggaggaaaggagttgggaccttcaataactaattattcacca
acaaggaacagtggaaaatccagttcataccatacaccagcaggatcctgtaaagtggcc
aatggtctggaaatggccattcccattactgtacaacagacattacctgacacaaagcct
gatgtggacacaacttgcagtgctcagaacactagaccaacagagggaactacttcagct
gacctggagctgtcagctcaacaagtgctggtagaaataaatgagaaaagacctcagata
gggagtaccaatataaaagctacactttctatattgaagaggcagccaaagtttctgtat
tgtttaaatgatgggaaaaatggtcaagatggaagaacaagggacattggtaaagtttca
cacaatgagcctattagaatacctgaaaaacatgctggatttggagaagttcaaaaggaa
ctggattcagtgaatgcagcatgtacacatatacagcaagatgcacaacttgaacctaaa
gaagactctgaatatttgaaagaggatgctctggatgtccaggaaattgaagaaaacctc
ttgaacttgaagcacgtggacaaaccaatttctaagcaagcaccccgtttagacactgct
actgacatttcaacaaccattaatatccaagcggatgtaaaggggacagaacacaggaat
actggagatgcctcaaagaaatccttgctggaatctgttagtatctccaaaaaaaacagt
attgataaaaatgtagggcacagtgatgttacattagctaaaaaacaagttatggaaaat
gaccattcttcagatgtcaccaaagaccataaagaacagcttgacagccacgaggaatgt
gctttttcaactacagagcatcacaatgccagcactgacagtcttccacttgatgtatct
ctttgcatcagaaaggttgagaactttggaggctttaaaacaggatctaacaagcttatt
tctatttcagaagaaaacctgagaaagggagaacttctgtttaaagacgatgatcctata
catcatattagtcaccctttacctccagctgttgacattaacaacactcttgacattgct
gattcagcatcagtgttcaatggattcagaacagcatcacgtaaggaaattaaagttgat
gaatgtaaaatcgctaagggaatgctcctgtttaaagatcttgaagatggaatgtgtgat
aacatcatcaccaataaggatttacgtacgccagctgctaacttggtgccagaaaatgag
aaagcaagagaaccagataataattttgagcccttgaacaagctgtcaacagaggagaca
aaggatagccgaacttcaaatctattacgcttaaacaaccattcctccaaagaagtccaa
attaaagggatgcgtagccaaaatgttttactcttgcaacatagcaaaagtagcacatct
gatggaaaaagccagaaggaaacaagtttatcttctgaaatccagtcccgcttctgtgag
atactgacagaaagtcagaaagctgaagtcagtgaactgtcttctattctcgagaatgca
gacagtcagtttgacttcacacagtttcggaaaaccggtaccgtaacatcaaataataat
caaaacttgcggagtgctgaagatggtattggcgaatctgagaatcttaataattctgat
gtttggaacgatgttgacttcaatgatagctttgcaactggagcagaacatgtagaaaat
aaagattccagtgtcaaattgtcattggaaaagaaagataactctgttggagcaactgct
tatgactctggtgtggcttcggtatctgaaaaattggtttccaaagacaaaaagaagaaa
tttggtggatttagcttagcgagtgggaaatgcataaacattactgatgacgatatggtc
aaagcttttgaattgttttgtgatttagatgataccacattgtcggtaaagcacccctca
acagatgtcaacaaagggaattttcctacaacttcagctgttccctcgacaccaaatgtt
cagcaagtttcaaaagattctatcactgttccgcgtaatgttaaggaatcgagcattgta
tactccaaaaccgaatcctctacaaaatgtgaaaaaaggagttcaacttttaatgaatat
atgtttaatagagagaaacataattccaaaatgaaattgatgaatgagtttgtggatagt
ggtaatgaggttagcggttctgaagaagcattttgtgtacaaaatatcaacactgcatcc
tgtggaagtcttgcttctgcttcttgtgtctcgacaatgccagttgggttttctactgga
aaaggcaaagttattagtgttgataaggcagctctagcaaaggcaaaatccatctttaat
gatctattacatccagatgacatagataggaatcaaggttcgacttccggtgtggttgta
aaggaaaatataaacacaattagtcatggtgaacctggcaagagaacacatgaactaact
gtcgaacaatctgctgttggtttcatcacaagtggaacaggtgctcctattcctcacgat
tctgtccagaaagaaaaaacaatttttgacaaggtctctggatcagaactggctcattgt
atatccttgcctaaggaagatactcttaatacaaagagagtggaatttagcactgcacat
ggtaaatctgttcatctttctgaagagtctttgaggagagctcaagagatatttgctgat
atagatgaccaccatctggtaactgttggggagaattctaaattcagtctgtgtgacgta
gagaagatcagttccaggtcacccaataccaacaacgtacaagatgtattaagcaaaacc
ctgcaagaaaaagagcctgtcctccctctactaggtttcagtacagctagtggtaaatct
gtagtagtctcttgtgattctctgcagaaagcaaaaatgatgtttgcagaaaccgatttg
gcagtacataatggacttgagggaatagagtaccagcaaatgcacgatagacctcggtca
aatccagctgaaattaaattgagtaagccgaacattaggggttgtaatgttgccacgaaa
aacaccacacaagtgattgttaatgtccctccacctctaggtttcagcacagcaagtggg
aaaacagtagcagtgtctaatgagtctctccaaaaagcaaggcggatgttatctgatact
gataatagtgggttggaaaatggatttcaatccagtcagactggacttgaaataggtaat
caggaaaaatgcagggatcttgttttgtgctcctcagaaaacacaaaacttagtaaggta
cgtctagcagagggtaatccaatgaaaccatttcttagagatggcaccactgattcttgt
ttggaaaaaactgatttaccacctatagtaaaaacgtccagagtagcacagcctagagat
atgcatttaccacaggaaactgcccccaatatagtgaagccatcttttatcacagcaggt
ggtaaacctcttcaaatgtcagaaaatgctttgaaaaaagcttgtgaaatgtttgctgaa
atagacgggcaattggaaaactcatgttctcttaaacagagtgtagaaagaaatactaaa
tggaataccccagagagcagcaatgtacaagacccagcatcacccactgtatcaaaggaa
acaatccttgcacttccagctccaggctttagcactgcaagtggaaagaatgtcgcagtg
tctgctgatgccctcctaaaagcaaggattttgctcgctgatggtgaagatggcattact
gatgaaagtatagctcaaggtaaaagcaaagcaatcagtgttaaaaaccgtgaagaaaat
gaaatgactttgaagcccagtacatttcactcaggcactaaagaattaatgtcactctct
aaaacgagccgtggtatgtatccattttctgaagaccatatgcctgaaaaagcttccaaa
atgttagtgaataacagttttatgcctgggatgccatgttttagcactgccagcggtaaa
acagtaactttatcagaagaggctttaaagaaagctcaacaaatattttcagaaatggaa
aactgtccctcgcaacaagacaaacttgaggacgttcttggtgacaatcctttacgtgta
tccaaagttcaaacatcattacatcaaaagccaaaagagcagacaactttagaaacttca
gaaacaagtaatttacctaaaacgactactaatagatttggatttagcacagcaagtgga
aaacaagtctctgtttcagaaacggcaatacagacagttaaggacctatttcaagagttt
acagaatctgaaaaccttcaagaacattgtcctaatgggaaaggtgacagcaacagtagt
aagacggcaaacacgctcactccattagtgaacaaagctgatgttattgctaattttaat
gacgagcttgttgaattgcagaaccacagggcaaggacaagagagaatattaacataggt
agaccatctattgcaagctcttgtgattctcagcgtccgatgcttaggcattccactcca
tttcacaatacaagagtacctagcaagaggaatactgtttcttcaatgacatctcgcaca
cctgagaactattttgaaattgaggctgctgaaagtgcaaaagctttcatggatgatgaa
gatttaactgatggtataatgaaagcagacgctaccaacaagcttctgattcttagaaat
gggaagcgattaagatctgatgatagaacttcacatggtgaaccaccaatcaaaagacag
cttttaccagaatttgacagatcgttgatgcaagaatcgaaactggctttgaaaccttta
acaagcagccctcatagtgattttaaagatagaagaaaatttgtatacaatgtttcttta
aaggcctcattctgtgatcctatgagcttttctgctggaaacaaggaagcccagaaatct
cagcttattactagatctgctgcttttcgacattcctcgtcagacatttctgctgatgct
tctgatgatggaaggcaactgaaagacataccttcttacaaaccagctactggcacatct
gaggaatggacaagtgaccaagatgacctagaaccacacaacagtgcggatgtttcccaa
ttgcttgcaagtctacattgtgccagagacctgcaagaaatgagagtacgaaagaaacaa
aggcagaacattaaaccatactcgggatcattgtatggactaaaagccacgtctacggac
agaattacactgatttcagcagtacaagggaagctgcctacaatgtacccaaaggaacag
ttgtacaggtttggcgttttaaaaaaccatattggaatcgacagtgagacagccaagatt
tttgacttccattgtttggattatttcacaaagagctgtctgtctggtggtggagtgcag
atcgcagatggtggttggctgataccttctgataaactgactgctggcagggaggagttc
tacagagctctatgtgacaccacaggcgtggatccgaagctgatctcctcagaatgggtg
tacaatcactataggtggattgtgtggaaactggctgcaatggaggtcatgttccctgaa
cagtttgcaggaagatgtctgacaccagagcgggtcctattacagctcaaatacaggtat
gaagtggaaattgataaaagccggagatcagctctcaagaggatcatggagagagatgac
acagccgccaagacccttgtgctttgtgtttctaaagtcatttcctggggaggcaatgat
aagagtgagtccaaagatactaagcaaggtcctgctgtcatagaggtgaccgatggctgg
tatggaatcaaggctttgttggacacttcgctaactgcattgctccacagaaggcggttg
ttcgttggtcagaaaataataatacatggggcagaattggtgggttcagaagaggcatgc
actcccctggaagctccggaatctcttatgttgaagcttgcagccaacagtactcgtcct
gctcgctggtataccaagcttgggtacttctgtgaccccagacctttttgcgttcctcta
tcatccctgcttgccgaaggtggcattgtggggtgcgttgacattgtcatacaaaggatc
taccctatacagtggatggaaaaaatggccaacggcacgtatgtattccgtaatgaccga
gcagagaaaagagaagcagaacgtcattctttgaaacagcaaaaaaatctggaagtctta
tttttgaagattcagcaagagtttgaacagcaggaggcatgcgaaagtaaagcaaaaggt
acaaagcgcaattctttaagtgtaacccaaattgctgcgcttcaggatggtgcagagatc
tatgaggcccttcagaatgaacctgatccaggatacttggagtcatgtatgagcagtgag
caactgcgtgtcctgaatcattacagacaggttattaatgataagaaacaagctctaatc
cagacagaattcaggaaagccattgaatctactgagcaagggtctgaagggtgcacaaga
agagaggtgacacctgtatggaaagtgcgcattgtggattacaaggagcaagatccaacc
tcagcctatatactcaacatatggcgccctttacctgatctagtctcccttctaaaagag
ggatgtcacttcaagatatatcagttggcgacttcccatccaaaatgcaaagcagacact
gcagctgtgcagctaaccgctacgaagaagacgcagttccagcagctgcagtcctcacag
gatatcctggaacagatttacacagagaggcaagtgaccgacttcagccagctcatggag
cctaattttaaaacggagtatggtgaagtcgacattgtgggcttggtgatatccatacac
caaaaaataggtgctgctcctattgtgtatttgtctgatgaagcccatgatattgtagcc
gttaagttctggatagacctgtctcagctctccctggaggaacttgcaaaaccgggtact
ttgattgcagccagtaaccttcgctggagatcagaatctactgctggaattcccatagtg
tcttttggagatctgtcctatattactgccaaccccaaagagacacatttacaaaaggct
attcacaaacttcgccagtctgtccaggctacccagaagttccaccatgaagcagagata
caactgttcaacatcctgagagtcccccatcccgaggagaaaccacctccagctcagcat
agttcggattcgtatgctgcaacaaccaagttctcaactccagcgggcaaacttggaagt
gcccagatgaatcccctgaatacccctagcaggagtaatacagtaatcatctccggtagt
gacatggacccaaagacttgcaagaagataaaaggtctggacctccttagccggatacct
tcccctccaccgataacgcccgtgcgcccctctgtgacgccatcattacagagagcgttt
cgtcctcctcgaagcatgcagaaagatgtacagaccagtgaacagcccattctgagtaaa
ggggaattcgtggacgatgaagaactggccatgatcaatacacaggctctggtttccggt
ttagagaaaaggaaaatacagcaaaaaatagaaatgtcagctgagaagacggaaaagatc
tctcctgaccagtctgatgggaaacctgatccttcaggtaatgatacaaagaaagaagac
actggccatgggaaactccacaaaagaagaagacacaaactttaa
DBGET
integrated database retrieval system
