Rana temporaria (common frog): 120933287
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Entry
120933287 CDS
T07929
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
rtem
Rana temporaria (common frog)
Pathway
rtem04217
Necroptosis
rtem04620
Toll-like receptor signaling pathway
rtem04621
NOD-like receptor signaling pathway
rtem05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
rtem00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
120933287 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
120933287 (TYK2)
04621 NOD-like receptor signaling pathway
120933287 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
120933287 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rtem01001
]
120933287 (TYK2)
Enzymes [BR:
rtem01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
120933287 (TYK2)
Protein kinases [BR:
rtem01001
]
Non-receptor tyrosine kinases
JAK family [OT]
120933287 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kinase-like
FERM_C_FAK1
RIO1
ABC1
Kdo
CttA_N
RA
Motif
Other DBs
NCBI-GeneID:
120933287
NCBI-ProteinID:
XP_040202348
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All DBs
Position
3:complement(438107563..438217071)
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AA seq
1180 aa
AA seq
DB search
MALCQCTVKHSDSDMEGCTFNGAGLRVYLYWSNGKEHYVSFTQTVTTAEEICIHIAQRLG
ITPLCYTLFALYDVQEKHWYPPNHQFNITKEMKLLLHFRMRYYFRNWHGMNEKEPIVCRN
VPKVSDSSEDKSRAEQTGAILDLASFEYLFEQGKFDFVNDIVSMKDFHSEQDVHKFKNES
LGMAVLHLSHIAIKKKVSLEEVAKQIGFKECIPKSFCHQIQQNNYLTKYRMRKVFKKFVR
HFHLHTVSPGKLSMEDVMYKYLSTLENLAPKFGCEIFRALSLELPKEDEKLSLYVNGGYM
DHTECTSKEPTATHQVMVRGMEGIRWRVMREEELLESVGQRSYFGKKSRGKGQKAGKPVT
RSEPSAPKWNHFCDFQDITHIVVSQSRVSLNCQNNQCLEILLPSYEEALSFVSLVDGYFR
LTTDSNHYLCHEVAPPRLVMSVANGIHGPLQEQYVVQKLKREEQVDGLYVIRWSAFNFNR
LIMTVKGSNQGKIFSYRQFRIDKVGELYTLEQWDRGFLSVKELTENLRGCTLRSGMETFH
VKQCILPKSGEVSNLTICRKGKNSKENAVSRNLNLSQLSFHQIRKHEISQKAHLGQGTRT
NIYEGVLMVSGGGDEDSEYESSELNNNSRDLRVVLKVLDPSHQDIALAFFETASLMSQVS
HIHLVFVHGVCVREAENIMVEEFIEHGPLDVCLRKDKHLITTGWKFTVARQLASALSYLE
DKNLVHGNVCANNILLARKGLEDGSSPFIKLSDPGVTFTVLSREERVDRIPWISPECVRN
IATLSTAADKWSFGTTLLEICFNGEVPLKERTPPEKERFYEKELGLPEPSCKELADLIGQ
CHNYNPSGRPSFRTILRELTQLQPQDLSDIASINPDFSIADPTVFQKRYLKKIRELGEGH
FGKVSLYCYDPNNDGTGEMVAVKSLKSGCSQQLETSWKGEIKILKTLYHENIVKYKGRCS
EQGDKIVQLIMEYVPLGSLRDYLPKHNVSLAQILLFAQQICEGMAYLHTQHYIHRDLAAR
NVLVENENVVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAAECLKECKFFYASDVWSF
GVTLYELLTRCDSYLSPPAKFIEMIGVTQGQMTVVRLIDLLDRGQRLPCPNDCPMEIYKL
MKDCWETEANFRPSFPNLIPILKSFRATYSTPAPSVFSVC
NT seq
3543 nt
NT seq
+upstream
nt +downstream
nt
atggctctgtgtcagtgtacagtgaagcacagtgattctgacatggagggctgtacattc
aatggagctgggctcagagtttacctgtactggagcaatggaaaggagcactatgtcagc
tttacccagactgtgaccactgcggaggagatctgtattcatatcgcacagaggctcgga
attactcctctctgctacactttatttgctctgtatgatgtccaagaaaaacactggtat
cctcccaatcatcagttcaacattaccaaagaaatgaaactgcttctccattttaggatg
aggtactatttcaggaactggcacggcatgaatgagaaggagcccatagtctgtcgcaat
gtgcctaaagtcagcgacagtagcgaagacaagagccgggctgagcagactggggctatc
ctggacttggcatcatttgagtatttgtttgaacagggaaaatttgactttgtgaatgac
attgtgtcaatgaaggattttcactccgaacaggatgttcataagtttaaaaatgagagc
ctaggaatggctgtactgcacctgtctcacattgccattaagaagaaagtatctttggaa
gaagtagccaagcagatcggcttcaaggagtgtattccaaaatcattttgccaccagatc
cagcagaacaactaccttaccaagtaccgcatgaggaaggtgttcaagaagtttgtccgt
catttccacctccatacggtgagccccggcaagctgagcatggaggacgtcatgtacaag
tacctgtccacgctggaaaacttggcacctaagtttggctgtgagattttcagggctctg
tccttagaactgcctaaagaggatgagaaactttcactttatgtcaatgggggttatatg
gaccacacagaatgtaccagcaaggaaccaactgccactcaccaggtgatggtgaggggg
atggaaggcatcagatggcgggtcatgagagaagaggagctgctggaaagcgtcggtcag
agaagttacttcggtaagaagagtcgaggtaaaggacagaaggctggtaagccggtgacc
aggtcagaacccagtgcacccaagtggaatcacttctgtgacttccaggacatcactcac
attgtcgtcagccagagtagagtcagcctcaactgtcaaaataaccagtgcctggaaata
cttctgccttcgtatgaagaagccttgtcttttgtgtctcttgtggatggttacttccgg
ctgaccacagactcaaaccattacctgtgtcatgaggtggcacctccacgtttggtgatg
agcgtagcgaatgggattcatggacccctacaggagcaatatgttgtccagaagctgaaa
cgagaggagcaagtggatggtttgtacgtcattcgatggagtgcatttaacttcaacagg
cttattatgacggtgaaaggatcaaaccagggtaaaatcttcagctacagacaattcaga
atagataaagtgggagaattgtacacactggagcagtgggatcgaggcttcctcagtgtg
aaggagctgacggagaacctacgaggctgcacactgaggtctggaatggagaccttccat
gtcaagcaatgtatcctccccaaatctggagaagtttccaacctgacgatctgtcggaag
gggaagaacagcaaagagaatgcagtatcacgaaacctgaacttgagccagctgagcttc
catcagatccgcaaacatgaaatctcacagaaagcccatttgggtcaaggcactcgcaca
aatatctatgagggggttctgatggtgagcggtggtggagacgaggactcggaatatgag
tccagtgagctgaacaacaactcgcgggatttaagagtggtcctgaaagtgctggacccc
agtcaccaagacatagcgctggctttctttgagactgcaagtctaatgagccaagtgtct
catatccacctggtgtttgtccatggagtctgtgtgcgggaggccgagaacatcatggtg
gaggagtttattgaacacgggccgttggatgtctgcttacgcaaagataaacatctgatc
acaacaggttggaagttcactgtcgctagacagctggccagtgctttgagttacctggaa
gataagaatttggtccatggaaatgtctgtgcgaataacatcctactggccaggaaaggc
ctagaagatggatcttctccgttcattaaactcagcgacccaggcgtgaccttcacagtg
ctgtccagagaggagcgtgtggacagaatcccatggatttcacctgagtgcgttcgaaat
atcgccactctcagtaccgctgctgacaaatggagtttcgggactaccttactggaaata
tgttttaatggggaagttcctttgaaggaaagaacacctcctgagaaagaacggttttat
gaaaaggagttgggcctccctgaaccatcctgcaaagagttggcggatctgattggacaa
tgtcacaattacaacccctcaggaagaccctccttccggacaatcctccgagaactaaca
caactgcagccccaggatctgtccgacattgcctccatcaaccccgatttctccatcgca
gaccccacagtgttccagaagagatacctgaaaaagatccgggagttgggagagggacac
tttgggaaagtaagcctgtattgctatgatccgaataacgatggtacaggggagatggtg
gctgtgaaatctctcaagtccggctgcagtcagcagctggagaccagctggaaaggagaa
attaagattctgaagaccctttaccatgaaaacattgtcaaatacaagggacgctgcagt
gagcaaggagataagattgtccagctaataatggagtatgtccctctggggagtctccgg
gattacctacccaagcacaatgtgagcctggcacaaatattactctttgctcagcagatc
tgtgaggggatggcttacctccacacccagcattacatacaccgcgatcttgcagcacga
aatgttttggtggagaatgagaatgtggtgaagatcggggactttggactggccaaagcg
gtgcctgaaggccatgaatattacagagtaagggaggacggtgacagccccgtgttctgg
tacgccgctgaatgtcttaaagaatgtaagttcttctatgcctcggatgtctggtcattc
ggagtgactctgtatgaacttctgactcgctgtgactcctatcttagccccccggctaaa
ttcatagagatgattggcgtcactcagggacagatgacggtggttcgactgattgatctg
ctggatcgaggtcaaaggttgccatgtccaaatgactgccctatggagatttacaaactg
atgaaggactgctgggagacggaagccaatttccgaccctcgtttcctaatcttatcccc
attctgaaatctttccgtgccacatacagcactcccgccccatctgtgttcagtgtgtgc
tga
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