Rana temporaria (common frog): 120938046
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Entry
120938046 CDS
T07929
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
rtem
Rana temporaria (common frog)
Pathway
rtem00562
Inositol phosphate metabolism
rtem01100
Metabolic pathways
rtem04020
Calcium signaling pathway
rtem04070
Phosphatidylinositol signaling system
rtem04081
Hormone signaling
rtem04082
Neuroactive ligand signaling
rtem04261
Adrenergic signaling in cardiomyocytes
rtem04270
Vascular smooth muscle contraction
rtem04310
Wnt signaling pathway
rtem04371
Apelin signaling pathway
rtem04540
Gap junction
rtem04621
NOD-like receptor signaling pathway
rtem04912
GnRH signaling pathway
rtem04916
Melanogenesis
Module
rtem_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
rtem00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
120938046 (PLCB4)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
120938046 (PLCB4)
04371 Apelin signaling pathway
120938046 (PLCB4)
04020 Calcium signaling pathway
120938046 (PLCB4)
04070 Phosphatidylinositol signaling system
120938046 (PLCB4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
120938046 (PLCB4)
04081 Hormone signaling
120938046 (PLCB4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
120938046 (PLCB4)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
120938046 (PLCB4)
09152 Endocrine system
04912 GnRH signaling pathway
120938046 (PLCB4)
04916 Melanogenesis
120938046 (PLCB4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
120938046 (PLCB4)
04270 Vascular smooth muscle contraction
120938046 (PLCB4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rtem04131
]
120938046 (PLCB4)
Enzymes [BR:
rtem01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
120938046 (PLCB4)
Membrane trafficking [BR:
rtem04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
120938046 (PLCB4)
Endocytosis
Macropinocytosis
Phospholipase C
120938046 (PLCB4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PH_14
PI-PLC-Y
PLCB1-4-like_EFh
EF-hand_like
PLC-beta_C
C2
Motif
Other DBs
NCBI-GeneID:
120938046
NCBI-ProteinID:
XP_040207636
LinkDB
All DBs
Position
4:465992267..466469507
Genome browser
AA seq
1206 aa
AA seq
DB search
MAKPYEFNWQKAVPAFMQEGAVFDRYEEESFVFEPNCLFKMDEFGFFLSWKSEGKEGQVL
ECSLINSIRCGAVPKDPKILSALESAGKAESDLEGRIVCVCSGTDLVNINFIYMVAESVD
VAKQWVEGLRSITHNFRANNVSPMTCLKKHWMKLMFLTNINGKIPVRSITRTFASGRTEK
GIFQALKELGFPSGKNEDIEHSTFTFDKFYELTQKICPRTDIEELFKTINGEKSDCLTVD
QLVSFLNQHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELRQKGQISSDGFCRYLMSDE
NAPVFLDRLELYQEMEQPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIREYAFVTSEYPVILSFENHCSKYQQYKM
SKYCEEIFGDLLLKQPLESYPLGAGKPLPSPNDLKRKILIKNKRLKQEVEKKQLEALKKM
MESGENVAPTSILEDDIEEEIENADQEEEAHPEYKFGSELSAEDLSQKEAVANSVKKVVE
DSEPENNNKKGQETVDDEQAWMANYKYVGATTNIHPFLSAMINYAQPVKFQSFKVAEEKN
IHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMV
SLNYQTPDLAMQLNQGKYEYNGSCGFLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQV
ISGQFLSDKKTGTYVEVDMYGLPTDTIRKEFKTRMVMNNGLNPVYNEEPFVFRKVILPDL
AVLRIGVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDG
FGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVSDNTKNDKKGKANNAKTSVTPQ
TSSELRQTTASTSGTTNEVKKGVEPIPQVKVEDLKQMKAYVKQLKKQQKELNALKKKQAK
EHSAMQKVHCTQVDKIVAQFDKEKLTLEKNLEKAIKKKGGNSCVEMKKETENKIQVLTSD
HKSKVKDIVAQHTKEWSDLISTHSAEEQELRDLHLSQQCDLLKKLLITVQEQQTQQLKLS
HDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDLLKKAQLEHLEILDKQNEQLLKSCHAVSNSQGKGNPADGQTGSRDGPQACNSCV
KLQNAN
NT seq
3621 nt
NT seq
+upstream
nt +downstream
nt
atggccaagccgtatgaatttaactggcagaaggccgtccctgctttcatgcaagaagga
gccgtgtttgacagatatgaagaggagtcgtttgttttcgagcctaattgcctctttaaa
atggatgagttcggcttctttctttcatggaagagcgaaggaaaggaaggccaagttttg
gaatgttccctgatcaacagcatacggtgcggggcagtgcccaaggatccaaaaatcctg
tctgcgctggagtccgctggaaaagccgaaagcgatctggaagggcggatcgtgtgcgtc
tgctccgggacggacctggtgaacatcaacttcatttacatggtggcggagagcgtggac
gtagcgaagcaatgggtagaagggctaagatctatcacgcataactttagagccaacaac
gtcagtccaatgacatgtctcaaaaaacactggatgaaacttatgttcctcaccaacatc
aatggaaaaatcccagttcgaagtatcacacggacatttgcatcaggaaggacggaaaaa
ggcatctttcaagcgctgaaagaattaggttttccgagtggaaagaatgaggacatcgaa
cactcgacttttacattcgataaattttatgagcttacacagaagatttgtcctcgaact
gacatagaagagcttttcaaaacaatcaatggagaaaaatcggattgtttgacggtagac
caattagtgagctttctaaatcaacatcaaagagatcctcgtctgaatgaaatcttgttc
ccgttctacgatgcaaagagagcaatgcagatcatagagatgtatgagccggatgaagag
ctaaggcaaaaaggtcaaatatcaagcgatggattctgccgatatctgatgtctgatgag
aatgccccagtctttctcgaccgattggaactctatcaggaaatggagcaaccgcttgca
cactatttcattagctcctcccacaatacataccttaccggcagacagtttggtggcaaa
tcatctgtagaaatgtacagacaggttcttctagctggatgcaggtgtgtggagctggat
tgctgggatggaaaaggtgaagaccaggagcccataattactcatgggaaggccatgtgt
actgatatcctatttaaggatgtaatacaagccatcagggagtatgcgtttgtcacctcg
gagtatcctgtaatcctttcatttgagaaccattgcagtaaatatcaacagtacaagatg
tccaaatactgcgaggaaattttcggggatctcctactgaagcagccccttgagtcatac
ccgctcggagctggaaaacctttaccgtctcccaacgacttaaagagaaagatcctcatt
aaaaacaagcgcttaaaacaggaagtggagaaaaagcagctcgaagccttgaaaaaaatg
atggagtctggggagaacgtggcaccaaccagcatcctagaagatgacatcgaggaagag
atcgaaaatgctgatcaagaggaagaagcccatcctgagtacaagtttggaagtgagctg
tcagcagaagacctcagccaaaaagaagctgtagctaatagtgtaaaaaaggttgtggaa
gactctgaaccagaaaacaataataaaaagggccaagaaactgtggatgatgaacaagcg
tggatggccaactataaatatgtaggagccacaaccaatatacatccgtttctgtcagcg
atgatcaactacgcccagccagtaaaattccagagctttaaagtggcagaagagaagaat
attcattacaacatgtcttcttttaacgaatcggttggattggggtatttgaagacgcat
gccattgagtttgtaaactacaacaaacgtcagatgagtcggatctaccccaaggggggg
cgagtggattccagtaattacatgccgcagattttctggaacgccggctgccagatggtc
tccctgaactatcagaccccagatttagctatgcagctgaaccaaggcaaatatgaatac
aacggatcttgtggtttcctccttaagccagacttcatgcgccgtcctgacagaacattt
gacccgttctcggagacccctgtggatggagtgattgcggccacctgctctgttcaggtt
atatccggacagtttctatcggacaaaaaaacggggacctacgttgaggtggacatgtat
ggactgccgacagacaccatccggaaggagttcaagacacggatggtcatgaacaacggc
ctgaatcccgtttacaatgaggagccatttgtatttagaaaggttatcctgcctgacctg
gctgtgctgaggatcggtgtgtatgacgacaataataaattgataggccaaaggatatta
ccactggatggtcttcaagctggctatcggcacatctctcttcggaatgagggcaacaag
cctctgtctctgcccaccatcttctgtaacattgtcctcaagacgtatgttcccgatggg
tttggagatattgttgatgctttatcagatccaaagaagttcctctccatcactgagaag
agagcagaccagatgagggcgatgggcattgaaactagtgacatcgcagacgtgtctgac
aatacaaagaacgataagaaagggaaagccaataacgccaaaacaagcgtcaccccccaa
accagctcggaactgcggcaaaccacggcgtctacttccggcacaaccaacgaagtcaag
aaaggtgttgagccgatcccacaagtgaaagttgaagatttaaaacagatgaaggcatac
gtcaagcagctaaagaagcagcaaaaagaactcaacgctctgaagaagaaacaggcaaaa
gaacacagcgctatgcagaaggtacactgcacacaagttgacaaaatagtggcccagttt
gataaggaaaagttgactcttgagaagaacttagaaaaagcgatcaagaagaaaggagga
aatagctgtgttgaaatgaagaaagaaacagaaaataaaattcaggttttaacttcagat
cataaatccaaggtaaaagatatcgtggctcagcatacaaaggagtggtccgatttgata
agcacccacagcgctgaagaacaggaactccgggacctccacctgagtcagcagtgcgac
ctcctcaaaaaactgctcattaccgtccaagaacaacagacgcagcaactgaaactctca
catgaccgagaaagcaaggagatgagggcaaaccaggccaagatttccatggagaacagc
aaagccataagccaagataaatccatcaagaataaggcagagcgtgaaaggcgggtgagg
gaactgaacagcagcaacacaaagaaattcctggaagagaggaaaagacttgcaatgaaa
cagtcaaaagagatggacctgctgaaaaaagcccagctagaacacctggagatcctggat
aagcagaatgaacagcttttgaaatcgtgtcatgcagtgtctaactcgcaaggcaaagga
aatccagcagatggtcaaactggaagccgagatggaccgcaggcctgcaacagttgtgta
aagctgcaaaacgcaaactga
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