Rana temporaria (common frog): 120941035 Help Entry 120941035         CDS       T07929                                  Symbol OBSCN Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism rtem  Rana temporaria (common frog) Pathway rtem04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:rtem00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     120941035 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rtem01001]     120941035 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rtem04131]     120941035 (OBSCN) Enzymes [BR:rtem01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      120941035 (OBSCN) Protein kinases [BR:rtem01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    120941035 (OBSCN) Membrane trafficking [BR:rtem04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     120941035 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 Izumo-Ig Ig_4 PK_Tyr_Ser-Thr Ig_6 V-set_CD47 fn3 SOS1_NGEF_PH C1-set RhoGEF Adeno_E3_CR1 Ig_DSCAM-DSCAML_C PH Egh16-like IQ SH3_2 Kdo Motif Other DBs NCBI-GeneID:  120941035 NCBI-ProteinID:  XP_040210210 LinkDB All DBs Position 5:complement(13113765..13754636) Genome browser AA seq 10284 aa AA seqDB search MDLSSFSGAPRFLTRPKAFMLSVGKDVTLSCQIIGNPIPQVTWEKNQAHIESGGRFKMTE DGGLYQLTIYDLTAEDSGQYICRAINNIGESFAAVTIKVGDEKEGTQVECAPFFILKPTN ARLNLGEDAIFRCRVQGLPRPVVSWEKDGRALGTPTDSNRICVEVDGESSSLRIHCIRFS DSGTYICRAESPVGQTKASASLLIDSFSNLNANSTAALEPAYGKTASLLSHLQRRREEIR KTDLSILGSYESNATSYGALDSLTSLGLSLSMDYERAATLTPKTGRDSSYNVLTRTCTVT EGKHAKMSCFVTGEPKPEIVWKKDGDVIAEGRRHVIYEDELENFVLKILFCKQIDNGLYT CTASNLAGQTYSSVLVIVKEPRIPFRSKLRDLEVREKETATFQCEVPQAITESSWYKEET QIQQSAKYSIEEEGTIRRLTIQNVNADDDAVYICEMKEGSRTIAELSVEGNFIKKLPRRT AIPVNDTAIFCVELDNDCQKSRWMINGEEVMPGGRISMTSVGKQHTMIIRECQNSDAGEI AFIADECKTSTKFTVTVLRKPPSNAPINPSVTEKTDTSLKLVWSPPPMDRPVPIDGYIVE RKKLGAMTWVRCHQSANVPVPEFTVSHVPDEGSYQFRVSAVNSYGQSPYLEFPGTLYLEP IPAIRLPLRPVEVAVGAEATFSIDLTTVSSGIWTVNGRVVENGEQYLVKRIKNTHMLVIK TVDPLFDQAEVKFTCKGIENSTKLRVKALPHFTNAKKASELKVNSGGQVELLSETSEENV RVAWYKDGKEIRHSKKFLQDVHGKQNKLTITSVRKEDEGTYSCSVGNDSVTFTLKVTEPE PSFTNLDKVQKEVHVKLSEKATLSCEISQEKTEVKWYKEGKLITSSKKMRVETEGRSRRL VVEQVEKKDAGEYTCEAAGQKINFKISVKELEPAFINQEKVQKEVTAILNECATLCCEVS DGKAEAKWYKEGKLITASKKQRLEVEGKYRRLVVEQVEKKDAGDYSCEVAGQKINFKIRV KEPEPSFSNLDKVQKEVQAVVSEKATLSCEVAQEKTEVKWYKEGKLVTSSKTVKVESEGR SRRLVVEQVEKKDAGEYTCEATGQKINFKINVKEPEAAFSNLDKVQKVVQAVVSEKTTLS CEVSQEKTEVKWYKEGKLITSSKKLKIETEGKTCRLVVEQVEKKDAGEYTCEAAGQKINF KINVKEPEPAFTNLDKVQKDVHVKLSEKTTLSCEVSQEKTEVKWYKDGKLITSSKKLKVE SEGKSRRLVVEQVEKKDAGEYTCEAAGQKINFKLNVKEPEPAFTNLDKVQKEVQAVVSEK TTLSCEVSQEKTEVKWYKDGKLITSSKKLKVESEGKSRRLVVEQVEKKDAGEYTCEAAGQ KINFKINVKEPEPAFIHQDKVQKEVQVLVSEKTTLSCEVSQEKTEVKWYKDGKSITSSKK LKLESEGKSRRLVVEQVEKKDAGEYTCEAAGQKINFKINVKEPEPAFISLDKVQKEVQVV VSEKATLSCEVAQEKTEVKWYKEGKLITSSKKLKAETDGKSRRLVVEQVEKKDAGEYTCE AAGQKINFKINVKEPEPAFIHQEKVQKEVQATLSEKATLSCEVAQEKTEVKWYKEGKLIT SSKKIKVETDGKSRRLVVEQVEKKDAGEYTCEAAGQKINFKINIKEPEPAFIHQEKVQKE VQAILSEKATLSCEVAQEKTEVKWYKEGKLITSSKKLKVETDGKSRRLVVEQVEKKDAGE YTCEAAGQKINFKINVKEPEPAFIHQEKVQKEVQAILSEKATLSCEVAQEKTEVKWYKEG KLITSSKKLKVETDGKSRRLVVEQVEKKDAGEYTCEAAGQKINFKINVKEPEPAFIHQEK VQNEVQAILSEKTTLSCELTQEKTEVKWYKEGKLITSSKKLKVETDGKSRRLVVEQVEKN DAGEYTCEAAGQKIKFKINVKEPEPAFIHQEKVQKEVQAILSEKTTLSCEVVQEKTEVKW YKEGKLITSSKTVRVETEGKSRRLVVEQVEKKDAGEYTCEAAGQKISFKITAKEPEPAFT SLDKVQKEVQAVVSEKTTLSCEVAQEKTEVKWYKEGKLITSSKKLRVESEGKSRRLVVEQ VEKKDAGEYTCEVAGQKINFKISVKEPEAKFQKILTQKESMVVQEHEDITLVTSVQPENA PVKWFKDGTELSATKKYQISADGASRTLVVKSAESKDSAVYSCRISSDKQEFKVQVKEVP VKFTKKLEAVTGEIGSAITLTCELGQAKGNVVWKRNGEEIKAGKRFQIQSDGAKRSLTVS QVKAEDGGEYSCESRDDKTITQLTTKAPRVVKFTAELNNVVVEEGAEATFKCTLTPEDAE LTWYRNGAKIEKSNKYSFSKKGTVHTLTISKLTMQDAGEIAAEAEGVKSTANLKVREAPV LFKKKLETMTVEERQTVHLETELTKASKEVKWMKNGIVLQSGGNIEIKSEGPKQILILKN VTYADRGLYGCETLDDKTQAKLNVEMRQVKLVKGLRDVEVRENDSATFELELSHEDVEGS WAKDGLRLKASDSCKLIVKGKKHGLVLSSVKQENAGAVTFKSEGIQTSAKLIVKEPPVKF SHPLKDITVAEKDKVTLECEVSRPNAEVKWLKDGSELRPSKKVTIISQGTKRNLTIHKCE FDDKGTYVCDAGDDKTSANLTVKAREIHFIKPLVDVEVEENGSASFLCQISHDDVQTQWY KNGVKLRAGENVKMRQEGRTYSLNFKSVQSEDAGEIKFAAENAESRANLLIKELPVKITK PLRDKIAIEKHRAFLECQVSRANAEVRWFKKDKQLQPGNRYEIVSQGVYRKLIINEVEFQ DEDTYTCDAGDDKTSAQLLIEEQSINIVNELSDVEVTQPEKAAFECVTSIVSVKPAKWFL GGEVLQDGKDITIEQEATIHRLILWKTSTEMTGAVQFHIGKSKSTANLVVKEIPVQVSQK LEDKTVSEPHTCVLSCEFKPPPKFVEWYRGKTLIEPSERYKLRQEKNLAELKIVRVTPED AGVYTCKAGSAETSATLHVQARDVKVLKPLANVEVEEESSVAFSCELSHDDEEVEWFLNN TLLYTNNYNDIKKIGACHTLTLKQVAPQDSGTVTLKTTKLTLNAELKVKEKPAVFMKSLD DAVGEERGTITLKCEVSKPNVTPVWKKDDQVLPNGDKYQQIQAGKTVSLIIHNLNKSDAG LYVCDIGTDVARSKVGVQELNIGITKRLKSTEAKDGESCTFECVLSHESIDECYWTVNGL EVENDRRFEVSNKGRKYSLNIKEVRASDAGDVVFTARNLSSKASLTVKGKPAVITKPLED KSVTAGENIVLKCEFSSEETSVKWTKDGKVLKRSQKYEIVQEGTESRLIIHETSSKDAGE YICETADSKTKAAVQITEKPNRFTKEISDVKAEEGEEAVFICETEKTAATVKWRKGISEL KASKKFEMTQKGNVLSLTVNDLEKSDSDTYICDIGDAQTKASLTVKGQKILIVEDLEDVE VYEGETATFKCRIAPANYGKVHWFLDKTPLHTNKVNEVQSLPGGYHTLSLNQLGVKDSGM VTFEAGDQKTSVKLLVKEKPSITNLEVSQGESATITYKTSKPNEPVSWYKDGKVVRSSSK YQITRSGCENTLIICDLTNKDSGTYVCEHGTGKNSTILAVKAVQAFFKREVQNAEAEEGE TATLFCELSNEKAEVRWKKDAKLLTSSSKYEIKIKDRRMELLVHNLTQEDSGTYTCETGE LNSSATLTVKAVQVLFKRGLRNEKAKEGSTVKLHCELSKAGAPVKWTKDDQILVSGEKYQ TKQQGTVVELLILNAKLEDSGDYTCDTGGQKSSSHVTVTALPVRFKQDLKDCEAEEGSSV TLSCEVTKADAHVAWKKGITDLKASDKYELRQKGTTVELLIHNITAEDSGNYTCDTGDQQ TAARVKVRELPTRFTKELTHQKATEGKSVSLCCELNKPDAQIEWKKDGEVIKQSKKHKPR QEGSMSELVIRDLVPDDAGNYSCVCGDQQTTAALTVTALPPLFKEELKDAKATEGEKAAL RCELTKPDATIEWRKGSQNLKAGVKYTIRQEGALAELIINILNENDAGSYTCVCGDRETT ATLTVNALPTFFKEKLVDKESMEGENLTLCCELSKPATAVVWKKGQTALKQSDKHKMTLK DTMAELTIQNLEFKDEGNYTCTCGEQETTASVKVNAKPVLFKEELKNIEGKEGSSVTLHG ELTKPPVAIEWRRGDEALQSSHKYDMRQDGAMVELLIRNLELEDTGEYTCMCGEEHSRAV LLVHALPVHFKHGLKDESTTEGDKVILHCELSKPNVPVQWEKENKVLPQSEKHVLRQDGL VAELVISDVNENDAGIYSCVCGDQKTSAAVTVKALPPKFKTELKNKECVEGQSAILNCEL TKENARLEWRKGNAVLQPNDKYKISQDGFNAELVVHNLAFQDGGQYSCMCGEQQTSATLV VNASPPEFKEELKSLEAVEGNSVTLHCELTKTNASLEWRKGQKIIKSSEKYKLVQEGLVA ELVVNNLDQHDTGRYICVCGDNQTAASLTVKALPPQFKEGLANKECVEGESVKLHCTLTK PKASLEWRKGQKTLKPGDKYKFVQEGLVAELVISQLDLEDAGDYTCVCGEHKTSASITVK ALPTQFKKDLKSKEVIEGTSATLICELTKPDAFLEWRKGHNPLKPSDKYRFIQEGLIAEL VLDNVEVKDAGEYTCICGNYRTTASLSVSALPPRFKDELQSKESMEGESVTLHCTLTKPN ASLEWRKGQKTLKPGDKYKFVQEGLAAELVISRVDLDDAGEYVCVCGDQQTKASLNMKAV PPRFKEELKSTEGLEGELASLRCMLTKPKAPLEWKKGQKTLKPGDKYRFIQEGLAAELVI NRLDLEDTGEYTCVCGDQHTTASLTVKALPIVFVEELRNELATEGQAATLRCELSKAGVA VSWKKNGSVIQASNKYVIKLEGAVTELTINNLDLKDAGGYTCVCGEQQTTAKLSVQELPP LFVEGLRNKEEIEGREAIFQCQLSKANAKAEWKKGHQTLKPDHKYKMRLQGVHAELVISN LHLKDSGNYTCLCGEEATTATLTVTELPARFSMELANVEATEGGMGIFHCEVTKKSASVQ WRKGATLLRPSDKYDMRQEGYRAELQINDLELTDADRYTCTCEDQKTSASLIVKALPVNF KEPLKNVEVMEGDAAALRCELSKPNQSVEWKKGPEVLTSGDRVSVGQDGSVAELIIQPVT IKDAGKYTCRCGDKMTTAVLTVNAIPVLFEEELKSVEATEGGTVTLHCRLNKSDVYVEWM KGDKVLVSDNNKYTMRQSGGTAEITVSDIGVEDSGEYTCVCGDVRTAGHLQVQALPITFT APLQNVEAQEEVTATLSCEVSKPGAAVEWRKGGLGLQPGPKYEMRQREKIRELLIHHLRL EDTGEYSCDSGDQDTRAYLTVKALPVVFSKPLKNTVVEDGVTVTLRCETSKPNVPLEWRK GSMALFPCAKYEMRQDGVVAELVVFDTEGEDAGDYTCDTGDQQTTSNVKVNVLQFVKNLE NVVAEEGSTACLRCEVSAKMASVEWRKGAEKLQANHKYEMKQDGTVRELIIHDLELEDNG EYVCIARSKRTTATLTVKELDVTIVRGLKDLSVFAGEDVVFKCEVSHANAKDVAWTLQGI TLVKNEMNEIWVESEKVHVLKMSSMTQEDSGPVTFRVGSHTSTAQLVVKAPLPVIKRQLS DVEVEEDATVVLQCELSQPGASLVWKKGAQQISQSAKYNILDHGAMQVLQILNVAPADSG VYTCDIGTQQTKAKVTVTALPVEFTRDLQNEQGEENGSVTLRAEISKPGAPVQWKKGGAA IKAGAKYEVKQSGHVVELHIHKLQQSDAAEYTCDTGDQKSVATVSVKEPEPYIVDQLQNV SVEEGEDAIFKCKVSKDNAPNVQWSLAGVPLQNNEMNEISVHRGKIHTLTLRKVTPEDAG LISFRVGQNSTEAKLEVKVVVLKFAKPLQPAEAEEQGSVTLNCELSKPNVAAEWRKGSLV IKHGGKYEVTVKGSVHSLRIKDVLLEDAGEYSCSAGGEKTSSKLQVKALPVVFTQELCNI EPEEGGMAMLECQVSKDGAPVEWRKGALVLQPSDKYEMRQSGTLVELVIHNVDMEDCGQY ACSTNSAQTVASVFVQESNVDLVSALKNTDVFAGETAVFSCELSSPSVRNVQWWLDGSPL QNSPVNEISVYGGTVHTLTLKNLGTNDSGVVTFRAGSLVSSAKLLIKDPTLEVVSPMNDL IIDEDDTAEFICQYSRPVQATWKKNDDVDVISDGKRIIVEQDWNVAKLTIKSVVPEDRGV YVCEADGTRVVAMLEVEAKNKILQGLENVDAIEGGEALFECYLAKAECYNYNWLVDDEPV KTTENIELVFFENGRRHLLLLKNLTSEDSCRVTFMAGDAVSSAFLNVRGWRLEVVNPPAD AKVTAGEKATFTCVLSEAVPVNEVSWYFNGLPVQPDENWSMQVEGNQYRLILNDAQLHHS GEVAFASRDVVASAKLAILALPDPPEEPEIVSKTSQSVTLSWFTPLSDGGAPIIGYNVEM KSPGGDWQQCNLEIIQSMEYVVQNLKPGEPYRFRISSINKLGVGEPVHLPQTVQLEHPVA IKQQLEDKTAREGESLRLECELSQETPEVAWMKENEPLQPGKKYECFSEGRKQILIIHNV SANDQGGYSCVTSSGVKTSATVSLEIRSITELITVQEAFTVAHEQSSLGVEDEDSAQPNL PPEAAQEGDLHLLWEALAKKRRMSKEPTLDSISEVPEEDDKHKKKADFSGYTSEDVAKTS EADFSLTSSDDESRAGTPSLVSYLKKAGHSTITYGAKVQTISTKKFFKHFEAATTEVKEV KKPEPQEELENLDDDPELEKAATKIQAAFKGYKARKVIKQQECPLFTETFKDLSVEPGGT VQLECVAIGKTDVTARWLKDDEELLDGRHYHIDNYSDGTCSLIITAVELQDTGKYTCEAS NKFGAVTHSAKLVVGGGVQDIPHRPIHIPAKRSRTTDSETESSSGSELDDAFRKAGRRLH KIFRTKSSLEISDVEEEIFVSADEGEMPPIDHQTYREDDRYIYIKFDIMSEATVAATRFR EMFSAMGFQVKIDILEQGPKKTELRIMKIETGATEQQRLQAKEQMTLMTTDTAPIFITEL QNQEVQDGYPVSFDCVVIGKPMPTIRWFKDGKVIEEDDHYMINEDQEGCHQLIITAVVPT DMGVYRCLAENRIGVASTKAELRVDLTSSDYDTAEAATETSSYLSAQGYMSREQESLESS TEQDQPPQILEELRDMLVAPDTPMAKFQIKVKGIPRPRVHWFKDGQPIHASERLLMTNKR KVRSLEILNVTKEDAGEYSTYISNSSGSAYSSARLTVKGPGELHKEKSTEGAAGSEKPIP PMFLERFTNKKVIKGSSITLSVKTEGIPSPTITWLKEESPEDVLWIKPDTPGYKVASSNR HHSLILLDVGTEFSGTYTCIATNKVGQSICSASVEVLDEKEAQLLEKADKIVKDVLRGAV PGAIAISVPPSEADGEAKPPKQQISLADVGTEEFFQKLTTQITEMVSAKMSQASLRVPGM PGMDSDDESKTPSASPRHGRSRPSSIAVESSSESEDGDSRGEIFDIYMATADYNPITVDK ETITLKEGQYVEVLDSAHPLKWLVRTKPTKLSASRQGWVSPAYLDKRLKLSPEWGSGDVV EFSGESISEEDYKKKLSTFVQDLLASEKEYVQDLQFLHTHYINYTETCADIPETVANQKT VIFRNISDIGDFHARTFFQELKNSDTDDDIAMCFIRNEEEFNKYIMYLVGRVQAESVVVN DAIQEFYKKYTEDTLALADPSQPPMPPLQHYLERPINRIHRYQIILKEMIRNKARNGKNC ALLEQAYAIVSALTRRAENFLFVSLIENYPGTLEALGEPIRQGHFIVWEGAPGARMAWKG HNRQVFLFKNYLIICKPKRDTRTDTYSYVFKNMMKLTNIDVNDQVEGDDRAFEIWHERED SVRKYLLQARTVIIKNSWVKEISGIQQRFSLPLWNPPQFIEVLADCTAELGETIKLACRV TGTPKPIVTWYKDGRTVEVDPHHIIIEDPDGSCTLILDNMSGVDSGQYMCFASSAAGNAS TLGKILVQVPPRFVNKLRNSYFVDGEDARFTCIIEGAPYPQIRWCKDGHLLPESNKYQTF GEPRTGTLVLVIKKASKEDVGYYECELANRLGSSRSGAELNVHTVASLTQERRGDQTITI EDLDEFIRASLQRADQEIRQVLQKLDSGTGLPVSPELTPEDIDIRKEVEQRLREEIRSME MFRDANTQTPEDTIHGTIRWPYQKNLPALFSHIPWIWDSSRSIIIISMLIVVVTFFYLCS GERKVESCVNEAVEVTPDVCCSETQTDEEKIIPIRLQMDASEWYRGRPSSQLWNIHHSQV YIETTDTTYLPLEDGKGTRPPYMQVTIEDVHANCGGTAQFDAVIDGSPPLAVTWYKDNTL LKDSDRIQLVRDGRKCSMVIRSTERGDGGVYTCVARNGGGEVSCKAELVMQEDEKEEDTK IVHKRRKLKSFFEVKEEIGRGSFGFVKRVVHKGNGATCAAKFIPLRSKTRQQAYRERDIL SEVSHERITLLLDAFETKKTLILILEICCGEELLDRLFRKHSITEKEVKLYIRQLLEAVA YLHEKNILHLDIKPSNILMVHTDKEDIKLCDFGFSQKIIQSEFQYSKYGSPEFVPPEIAA QAPVSKSSDIWPVGVISYLCLVSASPFAGQNDRETLMNVQQGKISWSCPGFTQLSANAQD FMRLAIQMSPDARPSATQCLQHKWFVEIPSLEDTQPVSSKNLRFLVARSRWQRSLMCYKS ILVMRSIPELLNGKQESTSLGVPRHLVECSSSSSSSGSSSDNESDVSPTARDCNPSLELH LSIFKMSEKDGLQQPSTPKPEMDKDTKCIPQEEENMESKDVTVHDTSPMIGTKREHDKAS GLSESQEDLKDDEKMLVHSVETSPGVLPLYRAATIEVGGLASKKAKTGSFIRGTSADSAL LIPRGAEKPSLVCVPRQSIINSTFYNQAGEGHGTAPRDATSKDKDFIKHRERARRSLMKA GYSQKILSGLREPLLEQFAMEQGILSQDSSQMDQMGSLKKSASFDLAKVSLRSSFKVSSR SRSLDDNRSRPLSVYKGTVVEEKDHISTKTSRDALNKSDTAITKPHSEEYWTAPPKVTST QRPLSAPPSDRENTIIAVFHQQPLQDNAECRAKSSSAVLGGEESTIIAFIKPKQITESES VAKTSSVVIKDTDVCPTPQSPRKASQEKEQPTDLQTGVKFTVHTTSRRNEFLVSDAPVER IPDRVNKFFPKDEEGEEVTKICEGQIQLVHFREDNSRLAVIHQGAGDILSLSKDITIQEV AECPTVMMQPEPVLDSVFPDRTPTELVIPDRPDHEHKLKPCVDQTFERDANFFVSLAQTL ESGITVLGDSMQIPGKDLPFSAYTDDQCATIDELVGEMSSLSEEMEVLVNEQRETSQVDP TFPSLVDQTKEPPELQDVGNFRGELQAMETEPSPLDEPIKEPPIVSISQCSYYESLSQAR VSPAPLEHFEEFTVESCSSSKTFISHSDSSGTGRRSDNFSDLEETGRHSEVSLVEIGGIH RDASSNDSNKMKLVPFDLESTHLNDFYDILTFQQHFTTEKNSQPAKDLSEAAMETSVKGA AKDTKTAIPLQPLQPSDPGKTALKERKSSRKRIKLFRHNGKSETKSSESSLKQKVKASVA NISRIIKKRQGNGKDATGTSEVHKVPAPEQAATIGVSVPPKKKGLSSFRLPSLSGKEKAP AFVEELTDQTVVVGHLVTLSCRTAQSVTNVEWFKDGVTIQSNERVLISSTLKNYHLLTIL VVNSQDFGIYACVATNLLGSASTCCILKKAEIPCCPTSPDVAQVYRDGALLVWKPVESNT PVTYFLQYRKEGEEWRALTLDISDCCYSTHNLSEGHLYSFRIACISKAGMGPYSDPSPSV RIGRPSPANLSGLREAGGPQGTPDGDQSSDLQKGVKRGRFSAVRLCTEKSTGRLLAAKII PYTEETKESTLLEFHILKKLHHTNVVQLHGAFLSPQDLALILELCEGRELLRCLSVGQSY SELEVRDYLWQILSAVEFLHAKQILHLDLRSENTIVTEHKLLKILDFGNAQFYSPDKVIS PQRYTDYMETMAPEVLEGQGAIPPTDIWAVGITAFIMLSADYPFSPDCGAELEKDIKKGL IRFGHCYAGLSGGAVRFLQSALWANPWGRPSASDCLKMPWLQEAGLATLQQQPPVYFPSA KLRSFLHRRADKTAASQSAGSSRS NT seq 30855 nt NT seq  +upstreamnt  +downstreamnt atggatttgagctccttcagcggggctccgcggttcctgaccaggcccaaagcctttatg ttatccgtgggtaaggatgtcacactgagttgccaaatcatcggaaatcccatcccccaa gtcacatgggaaaagaaccaggcccacatcgagtcaggaggccgcttcaagatgacagaa gatggtggcttataccagctcaccatatacgacctcaccgcagaagacagcggccaatac atctgtagggccatcaacaacattggagaatctttcgccgccgtcaccatcaaggttggg gatgaaaaggaaggcacccaagtggaatgcgcgccatttttcattctcaaaccaaccaac gccaggctgaacctgggagaagatgccattttccgctgcagagttcagggtctcccgcgg ccggtcgtcagttgggaaaaagacgggagggctttggggacgccgaccgactcaaacaga atttgcgtcgaggttgacggggagtcgagctctttgaggatccactgcattcggttttca gatagcgggacatacatttgtcgggccgagagccccgtgggccaaaccaaggcgtccgct tcgctgctcatcgactctttctccaacctcaacgccaacagcaccgccgctcttgaacct gcttacggtaaaacggcatcgcttttgtctcacctgcagagaaggcgagaggagatacgg aaaactgacctttccatcctcggttcctatgagtccaacgcaacttcctacggtgctctg gactcactgaccagtctaggcttaagtttgtccatggactatgaaagggcggctactctt accccaaaaacggggcgcgatagctcctacaacgtcctcacacgcacctgcacggtgacg gagggcaaacacgccaaaatgagttgttttgtcactggggagcccaagcccgaaatcgtt tggaaaaaggatggggatgtcatcgcggaagggcgcaggcacgtcatctatgaggacgag ctagagaacttcgtcctgaagattttattctgtaaacaaatcgacaacggattatacacg tgcacggcttccaacttggccggtcaaacctacagctcggtgcttgtcatagtgaaagaa cccagaatcccctttagatcaaagttgagagacctggaagttcgagagaaagagaccgcc accttccagtgcgaggtccctcaagccattactgaatcatcatggtacaaggaggaaacc cagatccagcagagtgccaaatacagcatcgaggaggaggggaccatccggagactcacc atacagaacgtcaacgcggacgatgacgcagtctacatctgtgagatgaaggagggcagc cgaaccattgcagagctctcagttgaagggaacttcatcaagaagctcccacggagaacg gcgatcccggtgaacgatacggccatcttctgcgttgagctggacaacgactgccagaaa tcgaggtggatgatcaacggtgaggaagtgatgccgggaggacggatctccatgacttct gtgggcaagcagcacaccatgataatccgagagtgccagaactccgacgccggggagatc gccttcatcgctgatgagtgcaaaacctccaccaagttcaccgtaaccgttttaaggaaa ccgccttccaacgccccaattaacccctcggtgacggagaaaaccgacacgtcccttaaa ttagtctggtcccctcccccgatggatcgcccggtgcccatcgatggctacatcgtagaa cgcaagaagctcggagccatgacctgggtcaggtgccatcaatcggccaacgtgcccgtc ccggagttcacagtcagccacgtgccggacgaagggagctatcagtttcgggtcagtgcc gtcaacagctatggacagagcccgtacctggagttcccgggaacgctgtacctagaaccc atcccagccataaggcttcctctgagacccgttgaggtcgcagtgggtgcagaagcaacg ttctccattgacctcaccaccgtatcttctggcatttggacggtcaacggccgtgtcgtt gaaaacggtgagcagtatctggtgaagcggataaagaacacccacatgctggtcatcaag actgtcgacccactgtttgaccaagccgaagtgaaattcacctgtaaaggcatcgagaac agcaccaaactccgagtgaaagctcttccccatttcacaaatgcaaagaaagccagtgag ctgaaagtgaattctggggggcaagtggagctgctctctgagacatcagaggagaacgtc agggtagcatggtacaaagatgggaaggagatacggcactccaagaagttcctccaagat gtccatggaaagcaaaacaagctcaccatcacctccgtcaggaaggaagatgaagggacg tactcatgcagtgtcgggaatgactccgtcacgttcacattaaaagttacagaaccagaa ccatccttcaccaatcttgacaaggtgcagaaggaggtccatgtcaaactgtcggagaag gccaccctgagctgtgagatatcccaggagaagacggaggtgaagtggtacaaggaaggg aaactgatcacctccagcaagaaaatgagggtggagactgagggtagatctcggcgtctg gtggtggaacaggtggagaagaaagatgccggagaatatacgtgtgaggccgccggacag aagatcaacttcaagatcagcgtcaaagaactcgagcctgctttcatcaaccaagaaaaa gtacaaaaggaagtgacagccatcttaaacgagtgcgccactctctgttgcgaggtgtcc gatggaaaagcagaggcgaaatggtacaaggaggggaaactgattaccgccagcaaaaag cagaggctggaagttgagggcaaatatcgtcgcttggtggtggagcaggtggagaagaaa gatgccggggattacagctgtgaagtggccgggcagaagattaacttcaagatcagggtg aaagagccagaaccatcattttcgaacctggacaaggtccaaaaagaggtccaagctgtg gtgtcagagaaggccaccttgagctgtgaggtggcccaggagaagacggaggtgaagtgg tacaaggaagggaaattggtcacctccagtaagacagtgaaggtggagtctgagggtaga tctcggcgtctggtggtggaacaggtggagaagaaagatgccggagaatatacgtgtgag gccacaggacagaagatcaacttcaagatcaacgtcaaagaaccggaggcagcattctcc aatctggacaaggtgcaaaaagtggtccaggctgtggtgtcagagaagaccaccctgagc tgtgaggtgtcccaagagaagacggaggtgaagtggtacaaagaagggaaactgatcacc tccagcaagaaactaaagatagagactgaaggtaaaacttgccgcctggtggtggaacag gtggagaagaaagacgccggagaatatacctgtgaggccgctggacagaagatcaacttt aagatcaacgtcaaagagccagaaccggccttcaccaatctggataaggtgcagaaggat gtccatgtcaaactgtcagagaagaccaccctaagctgtgaggtctcccaggagaagacg gaggtgaagtggtacaaggacggcaaattgatcacctccagcaagaaattgaaggtggag tctgagggtaaatctcggcgtctggtggtggaacaggtggagaagaaagatgccggagaa tatacctgtgaggccgccggacagaagatcaacttcaaactcaacgtcaaagaaccagag ccggccttcaccaacttggacaaggtgcagaaagaggtccaggctgtggtgtcagagaag accaccctgagctgcgaggtctcccaggagaagacggaggtgaagtggtacaaggacgga aaactgatcacctccagcaagaaactgaaggtggagtctgagggtaaatcacgccgtctg gtggtggaacaggtggagaagaaagatgccggagaatatacctgtgaggccgccggacag aagatcaacttcaagatcaacgtcaaagaaccagagccggctttcatccaccaggacaaa gtccagaaagaggtccaagttcttgtctcggagaagaccaccctaagctgtgaggtctcc caggagaagacggaggtgaagtggtacaaggacggaaagtcgatcacctccagcaagaaa ctgaagctggagtctgagggtaaatctcggcgtctggtggtggaacaggtggagaagaaa gatgccggagaatatacctgtgaggccgctggacagaagatcaactttaagatcaacgtc aaagaaccagagccggcatttatcagtctggacaaggtacaaaaagaggtccaggttgtg gtgtcagagaaggccaccctgagctgtgaggtggcccaggagaagacggaggtgaagtgg tacaaggaagggaaactgatcacctccagcaagaaactgaaggcagaaactgatggtaaa tcacgccgtctggtggtggaacaggtggagaagaaagatgccggagaatatacctgtgag gccgccggacagaagatcaacttcaagatcaacgtcaaagaaccagagccagcatttatc catcaagaaaaggtccaaaaagaagtccaggctaccttgtcagagaaggccaccctgagc tgtgaggtggcccaggagaagacagaggtgaagtggtacaaagaagggaaattgatcact tccagcaaaaaaattaaggtagaaactgatggtaaatcacggcgtctggtggtggaacag gtggagaagaaagatgctggagaatatacctgtgaggctgccgggcagaagatcaacttc aagatcaacatcaaagaaccagagccagcattcatccatcaagaaaaggtccaaaaagaa gtccaggctatcttgtcagagaaggccaccctgagctgtgaggtggcccaggagaagacg gaggtgaagtggtacaaagaagggaaactgatcacctccagcaagaaactgaaggtagaa actgatggtaaatctcggcgtctggtggtggaacaggtggagaagaaagatgccggagaa tatacctgtgaggccgccggacagaagatcaacttcaaaatcaacgtcaaagaaccagag ccagcattcatccatcaagaaaaggtccaaaaagaagtccaggctatcttgtcagagaag gccaccctgagctgtgaggtggcccaggagaagacagaggtgaagtggtacaaagaaggg aaactgatcacctccagcaagaaactgaaggtagaaactgatggtaaatctcggcgtctg gtggtggaacaggtggagaagaaagatgccggagaatatacctgtgaggccgccggacag aagatcaacttcaaaatcaacgtcaaagaaccagagccagcattcatccatcaggaaaag gttcaaaatgaagtccaggctatcttgtcagagaagaccaccctgagctgtgagctgacc caggagaagacggaggtgaagtggtacaaagaagggaaactgatcacctccagcaagaaa ctgaaggtagaaactgatggtaaatcacggcgtctggtggtggaacaggtggagaagaat gatgccggagaatatacctgtgaggccgccggacagaagatcaaattcaagatcaacgtc aaagaaccagagccagcattcatccatcaggaaaaggttcaaaaagaggtccaggccatc ttgtcagagaagaccaccctgagctgtgaggtggttcaggagaagacggaggtgaagtgg tacaaagaaggaaaattgatcacctcaagtaagacagtgagggtcgagactgagggtaaa tctcggcgccttgtggtggagcaagtggagaagaaagatgccggtgaatatacctgcgag gccgccggacagaagatcagctttaagatcaccgccaaagaaccagagccggcattcacc agcctggacaaggtccagaaagaggtccaggctgtggtgtcagagaagaccaccctgagc tgtgaggtggcccaggagaagacggaggtgaagtggtacaaagaagggaaactgatcacc tccagcaaaaaacttagggtggagtctgagggtaaatctcggcgcctggtggtggagcag gttgagaagaaagacgccggagaatatacttgtgaggttgccgggcagaagatcaacttc aagatcagcgtcaaagaacccgaagccaagtttcagaaaatccttacacagaaggaatca atggttgtccaggaacacgaagacataacattggtgacctcagttcagcccgaaaatgct ccagtgaaatggttcaaagatggaacagaattgtccgctaccaagaagtaccaaatatct gcagatggtgcatccaggacattggtggtgaaatcagcggagtctaaggacagcgccgtg tactcctgccgcatcagcagcgacaagcaggaatttaaggtccaagtgaaagaagtcccg gtgaagttcacaaagaaactggaagctgtgacgggagagatcggttctgccatcaccctg acctgtgagctgggacaggcgaagggcaatgttgtctggaagaggaacggagaggagatc aaggccggcaaacgctttcagattcagtccgatggagccaagcgcagcctgactgtctct caggtgaaggcggaggatggaggggagtattcctgtgaatcccgggacgataaaaccatc acacaactcacaaccaaagctcctcgggttgtgaagtttacagcagaactgaataacgtg gtagtagaggaaggtgcagaagccacatttaagtgcacattgaccccagaagacgccgag ttgacgtggtacagaaatggggccaagatagaaaagagcaacaagtattcgttcagcaag aaagggactgtgcacaccctgaccatcagcaagctgaccatgcaagatgccggcgagatc gcagctgaggctgagggggtgaagtcaacagctaacctgaaggtccgagaggctccagtc ttgtttaagaagaagttggaaacgatgacggtggaggagcggcagacagtccacctggaa acagagctgaccaaagcctccaaggaagtgaagtggatgaaaaacggtattgtgcttcag tccggcggtaacattgagattaaatctgaaggaccaaaacagatcctcatcttgaagaac gtgacctacgccgaccgagggctgtacggctgcgagactctggatgacaagacgcaggcc aagcttaatgttgagatgcggcaggtgaagttggtgaaaggtctccgggatgtggaggtc cgtgagaacgactctgccaccttcgaactggagctttctcatgaagacgtggaaggttcc tgggccaaagatggactaagactaaaagcctccgattcctgcaaactcatcgtcaagggc aagaaacacggactcgtcctctcctctgtaaaacaagagaacgccggagccgtcaccttt aaatcagagggaattcagacctccgccaagctcatcgttaaagaacctccagtgaagttc agccatcctctcaaggacatcactgtggcagaaaaggacaaggtgacattggagtgtgag gtgtccagacctaatgccgaggtgaaatggctgaaggatggatctgaattacgtcccagc aagaaggtcaccattatctcccaaggcacaaagagaaacctcaccatccacaagtgcgaa tttgacgacaagggcacctacgtctgcgacgccggggacgacaagacatctgccaacctg accgttaaagctcgggaaatccatttcattaagccattagtggatgtggaggtggaggag aacggatcagcctcgttcctctgtcagatctctcacgatgacgtccagactcagtggtac aaaaatggcgtcaagctgagggcaggagagaatgttaagatgcgtcaggaaggaaggacg tattctttgaacttcaaaagcgttcagtctgaggatgctggagagattaaatttgcggca gaaaatgccgaatctcgtgctaatctgcttattaaagaacttcctgtcaaaatcaccaaa cccctgcgggataagatcgccatagagaagcatagggcattcctcgagtgccaagtgtct cgtgccaacgccgaagtcaggtggttcaagaaggacaaacagcttcagccaggaaatcga tatgagattgtcagccaaggggtgtaccggaaactcatcatcaatgaggtggagttccag gatgaggacacttacacctgcgacgccggggatgacaagacctccgctcagttgctgatt gaagaacaatccatcaacattgtcaacgaactgagtgacgtggaggtgacgcaacctgaa aaggccgcctttgaatgcgtgacgtctattgtgtccgtcaagcccgcaaaatggtttcta ggtggtgaagtcctacaagatggaaaagacattacgattgagcaagaggccaccatccat cgtctcatcttatggaaaacgtctacagagatgaccggagccgttcagttccatattgga aaatccaaatccactgcaaatttggtggtgaaagaaattcctgtgcaggtgtcacaaaaa cttgaagacaagaccgtcagcgagcctcacacgtgcgtcttgtcctgcgaattcaaacct cctccaaagtttgtggaatggtacagagggaagacgctcattgagccatcggagaggtac aagctaaggcaggagaagaacctggcagagctgaaaattgtaagggtgaccccggaagat gccggagtgtacacctgcaaagctgggagcgccgaaacttcagcaacacttcatgtacaa gcgcgcgacgtgaaagtgctgaagccactggccaacgtggaagtagaagaagagagcagc gtggccttctcctgtgagctctcccatgacgatgaagaagtggaatggttcctgaataac accctactgtacacaaacaactacaacgacatcaagaaaattggagcctgccacacgctg accctcaaacaggtggccccccaggactccggcaccgtgactttaaagaccacaaaactc acgctgaacgcggagctaaaagttaaagaaaagccagccgttttcatgaaatccttggac gacgcagtgggtgaagagcgaggaacgattacgctgaaatgtgaagtctccaaacccaac gtcacaccagtgtggaagaaggatgaccaggtcttaccaaatggagacaagtaccaacag atacaggccggcaagaccgtctctcttatcatccacaacctgaacaagtccgatgccgga ctatatgtctgcgacattggaactgacgtggccaggtccaaagttggagtacaagaactc aacattggaatcacaaaacgcctaaagagcactgaggcaaaggacggagagagctgtacg ttcgaatgtgtcctttctcatgagagtatagacgaatgctactggacagtgaacggactg gaggtggagaatgatcggaggttcgaggtgtccaataagggccggaagtactcactaaac atcaaggaggtgagagccagtgatgccggtgatgtggtcttcactgcccgaaacttatcc tccaaggcctccttaactgtcaaaggtaaaccagctgttatcacaaaacctcttgaagac aagtctgttactgctggagaaaacattgtcttgaagtgtgagttttccagtgaagagacg agcgtgaaatggaccaaggatggcaaagtgctgaagaggagccagaaatacgagattgtt caagaaggtacggaatccaggctgattatccatgaaacatcatccaaagatgccggagaa tacatctgtgagactgctgattccaagaccaaagccgctgttcagatcacagaaaaaccc aatcgattcaccaaagagatttctgatgtcaaggctgaggaaggggaggaggccgtattt atctgcgagactgagaaaactgctgctaccgtaaaatggaggaaaggcatctctgaactc aaggcgtctaagaaatttgagatgactcagaagggcaacgtcctcagcctgactgtgaac gacctggagaagagtgacagtgacacctacatatgtgacattggagatgcccagactaag gcctctctcactgtgaaaggccagaaaattctcatagtagaagatctggaagatgttgaa gtatatgaaggggaaactgcaacttttaaatgtagaatcgcaccagcaaactatgggaaa gtgcattggttcctggacaaaaccccgttacataccaacaaagtcaatgaagttcagtca ctaccggggggctatcacacactgtcgctcaaccagctgggggtgaaggattctggcatg gtcacgtttgaagctggtgatcaaaaaacatctgtaaaactattagtgaaagagaaacct tctatcaccaatttggaagtatctcagggcgaaagtgcaaccattacttacaaaacctca aaacctaatgagcctgtttcctggtataaagatgggaaagtggttcgcagttcttcaaaa tatcaaataaccagatccggatgtgagaacacactgatcatatgcgacctgaccaacaaa gacagcggcacatatgtctgtgaacatgggacgggcaaaaatagcacaattcttgctgtg aaggcggtgcaggctttcttcaaacgtgaagtgcaaaacgctgaagccgaggaaggtgaa acggcaacgcttttttgcgagctgtccaacgagaaagccgaggtgcgttggaagaaggac gccaaactgctgacatccagtagcaagtatgagattaagataaaagaccgcaggatggag ttactggtccataacctgacccaagaagactctggaacctacacctgcgaaaccggagaa ctgaactcttctgccaccttgacagtgaaggccgttcaggtcttgttcaaacgaggcctc cgtaatgagaaggccaaagaaggaagtacggtgaagctacactgtgagctgagcaaggcc ggagctcctgtgaagtggacgaaggacgaccaaattctagtgagcggtgagaagtaccaa accaagcaacagggcacggtggtggagcttctcattctaaatgcaaaactagaagattct ggagactacacatgtgacaccggaggccagaagagctcatctcacgtgactgtaactgct cttcccgttcgctttaagcaagacctgaaagactgcgaagcggaagagggctcatcggtc actctttcctgtgaggtcaccaaggctgatgcccatgtggcgtggaagaagggcatcacc gaccttaaagccagtgacaaatatgagctcagacaaaagggaaccacggtggagcttctc attcataacataacggcggaggattctggaaactacacctgcgatactggcgaccagcag actgctgcacgggtcaaagttcgggagcttccaacccgctttaccaaagagcttacccac cagaaggctaccgaggggaaatcagtgagtttgtgctgtgaactcaacaagcccgacgct caaatagagtggaagaaggacggggaagtcataaaacaaagcaagaaacacaagccacgc caggaaggttccatgtcggagctggttatacgtgacctggtgccggacgacgctggaaat tactcttgtgtctgcggggaccaacaaacgacggctgctctgacagtaactgctttacct ccattattcaaagaagagcttaaggatgcaaaggctacagagggagaaaaggccgccctt cgatgtgagctcaccaaacctgatgccaccatagaatggagaaaagggagccagaattta aaagctggtgtcaagtacaccataaggcaggaaggggcccttgctgaattaataattaac attctaaacgaaaatgatgctgggagttacacatgcgtttgtggagaccgggaaaccaca gccactttgactgtgaatgctcttccaaccttctttaaagaaaaactggttgacaaagaa tccatggaaggagaaaatctcactctctgctgtgagctttctaaaccagccaccgccgtt gtttggaagaaaggtcaaacggccttgaaacaaagtgataaacataagatgaccttaaaa gacacaatggctgagctgaccatccagaatcttgaatttaaagatgaaggaaattacacc tgcacatgtggagagcaagaaaccacagcaagtgtaaaagtcaatgccaagcctgttctt ttcaaagaagagttgaagaatatagaaggcaaggagggctcttcggttacactgcatgga gagctgaccaagcctccagtggccattgagtggagaagaggagatgaggcgctccagtca agtcacaagtatgacatgaggcaggacggagcaatggtagagctcttaatacgaaatttg gagctagaagacactggagaatacacgtgtatgtgcggagaggagcactccagagcagta cttttagttcatgcactgcctgtccacttcaagcatgggctcaaggatgagagcacaaca gaaggtgataaagtcatcctccactgtgagctcagcaaacccaacgtacccgtgcaatgg gaaaaagagaacaaagttcttccccaatcggagaagcatgtcctaagacaagatggctta gtggcagaacttgtcatttcagacgtcaatgaaaatgatgcgggaatatacagctgtgtc tgcggagaccaaaaaacatctgcagctgtaactgttaaagctttgccacccaagttcaaa actgagctaaaaaacaaagagtgtgtggaagggcagtcggccattttgaactgtgagctg accaaggaaaacgctcgcctagaatggaggaaaggaaacgcggtcctccagccaaatgat aagtacaaaattagccaggatggctttaatgccgaacttgtggttcacaacttggctttt caagatggaggccaatactcttgtatgtgtggagagcaacagacttcagctacattagta gtgaatgcttcgccgccagaatttaaagaggaactgaaaagccttgaagccgtagaaggg aactctgtaactttgcactgtgagttgaccaaaacaaacgcttccctcgaatggcggaaa ggacagaaaattatcaagtcaagtgaaaagtacaagctcgtacaggagggcctggtggca gaactggttgtaaataatctggaccaacacgataccgggagatacatttgtgtctgtggg gataaccagactgccgcgtcattgactgtgaaggcacttcctccacagtttaaggaagga ctagcgaacaaggaatgtgttgaaggtgagtcagtgaaattgcattgtacgttgaccaag ccaaaagcttctctggagtggaggaaaggccagaagacccttaaacctggagataaatat aaatttgtccaagaaggtcttgtcgctgagttggttattagtcaactggacctggaggat gcgggagactacacatgtgtgtgcggagaacataaaacatcggcctccataactgtgaag gcccttccaacacaatttaaaaaggatctaaaaagcaaggaagttattgagggaacttca gccacgctaatctgcgagttgacgaaacccgacgcattcctagaatggagaaaaggacac aatcctctcaaaccaagtgacaagtaccggttcatccaggagggccttattgctgagctg gtgttagataacgtggaggtgaaggatgccggcgagtacacttgcatatgtggaaactat cggacaactgcgtccctgagcgtgagcgctcttccacctcgatttaaagatgaacttcag agcaaagaaagtatggagggggaatctgtgactctgcattgcacattgaccaaaccaaat gcttctctggagtggaggaaaggacagaagactcttaaacctggagataaatataaattt gtccaagaaggtcttgccgcagaactagttataagtcgagtggacctggatgatgccggg gaatacgtgtgtgtttgtggagaccagcaaacaaaggcatccctcaacatgaaggctgtt cctccgcgatttaaggaggaactgaagagcacagaaggcctggagggagagttggcatcc ctacgttgtatgctgaccaaaccaaaagctccgctggaatggaagaaaggacaaaagact cttaaacccggagataaatacaggttcatccaggaaggtcttgccgcggagttggtaata aatcggttggacctggaagataccggtgaatacacatgcgtgtgtggagaccagcatacc accgcatctcttaccgtgaaggctcttcccattgtctttgtggaggaactgagaaatgaa ttggcaaccgaaggccaagctgccactttgcgctgtgagttgagtaaggccggtgtcgcg gtgtcttggaagaagaacggttctgtcatccaagcaagtaataagtacgtcataaagctg gagggagcagttacagagctgaccattaacaatctggatctgaaggatgctggaggttac acctgcgtgtgcggagaacaacaaactaccgcaaaattatcagtacaggaactgcccccg ctatttgtagagggactacgaaacaaagaagaaatagaaggccgagaagccatttttcaa tgccagctcagcaaagccaacgcaaaggcggagtggaagaaggggcaccagaccctgaaa cctgaccacaaatataagatgagactgcagggtgtccacgctgaactcgtcatctccaat ttacacctgaaggattctgggaactacacctgtctgtgtggggaggaagcaactaccgcg accctgacagtaactgagttgccagcccgtttcagtatggagttggccaacgttgaagct acagaaggaggaatgggcatctttcattgtgaggtgaccaagaaatccgcttcagtgcaa tggaggaagggtgcgactctgctgagaccaagcgacaaatacgacatgagacaggaagga tatagagcggaactccagataaatgatctggaactgaccgatgcggaccggtacacctgc acttgtgaagaccagaagacctcggcctccctgatagtcaaggctctaccagttaatttt aaggagccgttgaaaaatgtggaagttatggaaggcgacgcggcggctctgcgctgtgag ctcagcaaaccaaaccagagtgtagagtggaagaaagggccggaagttctgacctcgggg gatcgggtcagcgtcggacaggacggctcggtggcggagcttatcattcagcctgttacc ataaaggatgctgggaagtatacctgcagatgtggtgacaagatgactacagcagttttg acagtaaatgctattccagtgttgtttgaagaggaactgaaatcggttgaagccacagag gggggaaccgtcaccctccactgccggctgaacaagtcggatgtgtacgttgagtggatg aaaggtgacaaggttctggtgtcagacaacaacaagtacacaatgcggcagagcggaggc accgcggagatcaccgtctcagacatcggtgtagaagacagcggggagtacacctgtgtc tgcggagatgtgcggacagcgggacaccttcaagtccaagctttgcctatcaccttcacc gcgccgctccagaacgtggaagctcaggaagaagttaccgccaccctgagctgtgaggtc tccaagcccggagccgcggtggagtggaggaagggcggcctggggctgcagcccggcccc aaatacgagatgcggcaaagggagaagatccgggagttactgatacatcacctgaggctg gaggacaccggagagtacagctgcgattccggggatcaggacaccagggcctacctgacc gtgaaagcccttcctgtggtgttcagcaagccgttgaagaatacggttgtagaggacgga gtcacagtgactctccgctgcgagacctccaaacccaacgttcccctagaatggaggaaa gggtccatggctctcttcccttgtgccaagtatgaaatgagacaagatggggtggtagca gagttggtagtcttcgacaccgagggggaagatgccggagattacacctgtgatacagga gaccaacaaaccacctccaacgtcaaagtcaacgttctccagttcgtgaagaatttagaa aatgtagtggctgaagaaggctcaactgcctgtctccgctgtgaggtctccgccaagatg gcctccgtggaatggagaaaaggtgctgagaaactacaagccaaccacaagtatgagatg aagcaggatgggactgtgcgggagctgatcattcatgatctggagctggaggacaacggg gagtatgtttgcatcgctcgaagcaaaagaactacggccacgctaactgtgaaggaactg gatgtcaccattgtccgtggcctcaaggacctgtccgtctttgccggagaggacgttgtg tttaagtgtgaagtctcccacgccaacgcaaaggacgtagcgtggaccttgcagggcatt acgctggtaaagaatgagatgaatgagatctgggtggaaagtgagaaggtccatgtcctg aaaatgagcagtatgacccaggaggacagcggtcccgtgactttcagagttgggtcacac acatctacagcccaacttgtggtcaaagctcctctcccggtgattaagagacaactctct gacgtggaagtggaggaggacgccacagtggttctacagtgtgagctgtcccagcccgga gcgtccctggtgtggaagaagggcgcccagcagatcagtcagagcgccaaatacaatatt ctggatcatggcgccatgcaggtcctgcagatcctcaatgtggcgcctgcagattccggc gtctacacctgtgatatcggaacccagcagacgaaggccaaagtgaccgtaacagcacta cccgtggagttcacgcgggatctacagaacgagcagggagaagagaacggatcggtgacg ctcagagccgagatctccaaacctggcgcccccgtgcagtggaagaaaggcggagcagcc attaaagccggggccaagtatgaagtgaagcaatctggacacgtggtggaacttcatata cacaagctgcagcagtccgatgcagctgagtacacatgcgacaccggcgaccagaaatca gtggctacagtgtctgttaaagaaccagaaccgtatatagtggatcagctccagaacgtg 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tcatggttcacccccttgagcgatggtggcgctccgattattggatacaatgttgagatg aaatcacctggtggtgattggcagcagtgcaacctggaaatcattcaaagtatggaatac gttgtgcaaaacctgaaaccgggcgagccttatcgtttcagaatctcctccataaacaag ctgggtgttggggaaccggttcacttacctcaaacagtccagctagagcatcccgtggca ataaaacagcagctggaagataaaactgcaagagagggcgagagtcttcgcctggagtgt gaactttcccaggaaactccggaggtcgcctggatgaaggagaatgaaccgctccaacca gggaagaaatatgaatgcttttctgaaggcagaaaacagatcctaatcattcataatgtc tctgcgaatgaccagggcgggtactcctgtgtgacctcatcgggggttaaaacctctgca accgtctctttggaaattcgatccatcacggaactgatcacagtacaggaggcttttact gtggcccacgaacagtccagtcttggagttgaagatgaagatagcgctcagccgaatttg ccccctgaagccgcgcaagaaggcgatctccatttactgtgggaggcattagctaaaaag agaagaatgagtaaggagcccactttggattccatctctgaggttccagaagaagacgat aaacacaagaaaaaagctgatttttcaggctatacctccgaagatgtggccaaaaccagc gaggcagatttctctcttacaagttcggatgatgaatcccgggctggaacgccatccctc gtgtcctatcttaaaaaagctggccattccactattacatatggggctaaagttcagaca atatctacaaaaaaattcttcaagcattttgaggccgccaccactgaagtcaaggaggtt aagaaaccagaacctcaagaagaacttgagaatttggatgatgatcctgaactggagaaa gcggcaacaaaaattcaagctgccttcaagggatacaaagcacggaaggtcatcaaacaa caagaatgtcctttgtttacagagaccttcaaagatctttcagtggaaccaggtggaact gtccagcttgaatgtgtcgccatcggcaaaaccgatgttacggctcgttggttgaaagat gacgaggagcttttggatggacgccattatcatattgacaactacagtgatgggacttgc tccctaattatcactgctgtagaactccaggacactggaaaatatacatgtgaagcgtca aacaaatttggagcagtgacccacagtgcgaaattggtggtggggggtggcgtacaagac atcccacataggccaatacacattccggccaagcgtagtcgtactactgacagcgagaca gagagctcttctggaagtgagttagacgacgccttccgaaaagcaggacggaggctgcac aagatctttagaacaaaatcttctctagaaatatccgacgtggaagaagaaattttcgtg agcgccgatgagggagaaatgcctcccattgaccaccagacctaccgagaggatgacaga tacatctacatcaaatttgatattatgtctgaagctactgtcgctgccacaaggttcagg gaaatgttttctgccatgggtttccaagtgaagattgacattcttgagcaaggcccaaaa aagactgagctacggataatgaagatcgaaacaggggctacagagcagcaacgccttcag gccaaggagcagatgactttaatgacaacagacacagctcctatatttattaccgagctc caaaaccaagaggttcaagacggctaccccgtcagttttgactgtgttgtgatcggaaag 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gaagcacagctcctggagaaagccgataaaattgtgaaggacgtattgaggggcgccgtt cccggagcaatcgcaatctcggtgccgccctcagaagcagacggtgaagccaagccacca aagcaacagatttccctagcagacgttggaacggaggagttcttccagaagctgaccaca caaatcacagaaatggtttccgccaagatgagccaagcttcccttcgagtgcctggaatg cccggtatggatagcgatgatgaatccaagactccctctgcttctccgcgtcatggcagg tccagaccatcctccattgctgttgagtcttcgtcagaatcagaagacggggactccaga ggagagatatttgatatctacatggccacagcagactacaacccaataacagttgataag gaaaccataactctgaaagagggccagtacgtggaagtccttgactctgcccatcccctg aagtggcttgtcaggacaaaaccaaccaagctaagtgcctcccgacagggttgggtatct cctgcatacctggataagcgtttgaagctatcgccagaatggggatcaggagatgttgtg gaattttcaggagaatcgatttcagaagaagattataaaaagaaactcagcacatttgtt caagatcttctagcctcagagaaggaatatgtccaggacctccaattcttgcatacccat tatataaattacactgagacctgtgctgatattcccgagactgtggccaatcagaagacc gttattttcaggaacatcagtgatatcggtgacttccatgccagaactttcttccaagaa cttaaaaactctgacacagatgatgacattgccatgtgcttcatcaggaatgaggaagag tttaataagtacatcatgtacctggtgggtcgtgtgcaggctgagtctgttgtggtcaat gatgccattcaggagttctacaaaaaatacacagaggacactttggcccttgctgacccc tcccagcctccgatgccaccactgcaacactatctggaacgaccgatcaacagaatacat cgatatcagatcatcctgaaggaaatgatccggaacaaggcaaggaacgggaagaactgc gcactgctggagcaggcttatgccattgtgtccgcacttacacgtcgggcagagaacttt ctgttcgtatcattgattgagaactacccaggaaccctggaggcattgggagaacccatc cgccagggtcatttcatcgtctgggaaggtgccccaggagcccgaatggcttggaaagga cacaatcgtcaggtcttcctcttcaagaattatctcatcatctgcaaacccaaaagagac accaggacggacacttacagctatgtcttcaagaatatgatgaagttgaccaacattgat gtgaatgatcaggttgaaggtgacgatcgggcctttgagatatggcatgaacgagaggac tcggttcgcaagtacctcttgcaagcccgcaccgtcatcatcaagaactcatgggtgaag gagatttccggcatccagcagaggttcagcctgccactgtggaatcctccacaattcatc gaagttttggcagattgtacagcagaactaggagagactattaagctagcctgccgggtc accggaacaccaaagcctatcgtcacctggtacaaagatggccgtacggtggaagtggat ccccatcacatcatcattgaagaccccgatggttcctgcaccctcatattggacaacatg agcggagtggactcaggacagtatatgtgcttcgcctccagtgcagccgggaatgccagc acgttaggaaagatccttgttcaagttcctccaagatttgtcaacaagctgcgcaattcc tactttgtggacggtgaagacgctcggttcacgtgcatcattgagggagctccgtaccca caaatccgatggtgcaaggatggacatctactgccggaatctaataagtatcagacgttt ggcgagccgagaacaggaaccctggtcctggtgataaagaaagccagcaaggaagacgtt ggctattatgaatgtgagttggcgaacagactggggtcctcacgtagcggagccgaactg aatgttcacacagtggcatcactgacccaagagaggaggggagaccagaccatcaccata gaagatttggatgaatttatacgggcatctctgcaacgcgcagatcaggagatcagacag gttctccagaaacttgactctggcactggcctacctgtgtctccagagcttactccagaa gacatagatattcggaaggaggtggaacaacggttacgggaagagatccgatcaatggaa atgttccgagatgctaacacccaaacccccgaggacaccatacatggtacgataaggtgg ccttaccagaagaatctccctgctctcttttcacatattccctggatctgggattcctcc aggtctattatcataatcagtatgttaatagtggtggtgacttttttttatttatgttca ggtgagcgaaaagtggagtcctgtgtaaatgaggccgttgaagtaactcccgatgtctgc tgttcagaaacacaaacagatgaggagaaaattatcccaatcaggcttcagatggatgca tcggagtggtaccgcgggagacccagctctcagctctggaatatccaccacagccaagtt tacatcgagaccaccgacaccacttacctgccgctggaggatggcaaggggacgagaccc ccgtatatgcaggtgactatagaagatgtgcacgccaactgtggggggacggcacagttt gacgcagttatagacgggagccccccgcttgccgttacctggtacaaggataacacgttg ctgaaggacagcgatcggatccagctggtgagagatggcaggaagtgctccatggtcata cggagcacagagcgtggcgatggcggggtgtacacctgtgtggccaggaacggcggggga gaggtgtcttgcaaggccgagctggttatgcaggaagacgagaaagaagaagacaccaag atcgttcataagagaaggaagctcaaatctttctttgaggttaaagaggagattggcaga gggtcatttggcttcgtgaaacgcgttgtgcacaaaggaaatggcgcgacatgcgccgcc aaattcattccactgagaagcaagactcggcagcaagcgtaccgcgagcgcgacatcttg tcggaagtgtcccatgagcgaatcactctgctccttgatgcctttgaaaccaagaagacg cttattcttattttggaaatatgctgcggggaggaacttctggaccgactcttccggaaa cactctatcacagaaaaagaggtgaagctgtatatcagacaactcctcgaagctgttgct tatcttcatgaaaaaaatattcttcatctggacatcaagccttccaacatcctgatggtt cacaccgataaggaagacattaaactctgcgacttcggattctcccagaagataatccag tccgagttccagtacagcaagtacggctcgcctgaatttgtccctccagaaatcgccgct caggcgcctgtatccaagtcttccgatatctggcctgtcggagttattagctacttatgt ttggttagcgcttccccattcgcgggtcagaacgacagagagacgctgatgaacgtacag caaggcaaaattagctggagctgcccgggcttcacccagctaagtgccaatgcccaggac 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tgcgtagaccaaacgtttgagagagacgccaatttctttgtttctttggctcaaacatta gaaagtggaataactgttctgggagatagcatgcaaattcccggcaaagacttgccgttt tcggcatataccgacgatcaatgtgccactatagatgaacttgttggtgagatgtcttct ttgtccgaagagatggaggtgttggtcaacgaacaaagggaaacaagccaagtagaccca acttttccatccttagttgatcaaaccaaggaaccaccagaactgcaagatgttggaaat ttcaggggagagttgcaagccatggaaacagagcccagtcctttggacgaacctataaaa gaaccaccaattgtatcaatctcacagtgcagctattatgaatctctatctcaggctcga gtgtcacctgcaccccttgaacactttgaagagttcaccgtagaaagttgcagttctagc aaaacctttatttctcattctgatagctccgggacagggaggaggtctgataacttctct gacttggaggaaactggacgccattcagaagtatcgcttgtggagattggagggatccat cgtgatgcatcttcaaatgattccaacaaaatgaagctggttccatttgatttggaatct actcatctcaacgatttttatgatattttaacgtttcagcaacactttaccactgaaaaa aattcacagcccgcaaaagaccttagcgaagcggcaatggaaacctcagtgaaaggagca gcaaaggacacaaagactgctattcccctacaaccattgcagccctctgatcctggcaag actgcactgaaggagcgcaaatcctccaggaaacgcattaaactcttccgacataatgga aagtcggagacgaaatcctcagagtccagtctgaaacagaaagtcaaagcttcggttgct 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catcacaccaacgtggtgcagctgcacggggcgtttctaagtccgcaggacctggcgctg atcctggagctctgcgagggccgcgagctgctgcgctgtctgtccgtggggcagtcatac tcggagctggaggtcagagactacctgtggcagatcctcagtgcagtggaattcctccac gctaagcagattcttcacctggatctgaggtcagagaacaccatcgtcaccgaacacaaa ctgctgaagatcctggacttcggcaatgcccagttctattccccggataaagtcatcagc cctcagagatacacagattacatggagaccatggctccggaggtcctggaggggcaggga gccatcccccccaccgatatctgggccgtcggaattacagcgttcatcatgttaagcgct gactatccattcagtcctgactgcggggcggagctggagaaggatatcaagaaaggattg atcagattcggccactgctacgccggtctgtccggaggggccgtccgcttcctgcagagc gcgctgtgggcaaatccttgggggcgtccctctgcatcagactgcctgaaaatgccgtgg cttcaggaggccggactggccacgttgcagcagcagccgccggtctacttccccagcgcc aaactgagaagcttcctccaccggagagccgacaagacagcagcaagtcagagcgcgggg tcatcgcggtcctga

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