Rana temporaria (common frog): 120943279 Help Entry 120943279         CDS       T07929                                  Symbol PKD1 Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism rtem  Rana temporaria (common frog) Brite KEGG Orthology (KO) [BR:rtem00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:rtem03037]     120943279 (PKD1)    04812 Cytoskeleton proteins [BR:rtem04812]     120943279 (PKD1)    04040 Ion channels [BR:rtem04040]     120943279 (PKD1)    04091 Lectins [BR:rtem04091]     120943279 (PKD1) Cilium and associated proteins [BR:rtem03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    120943279 (PKD1) Cytoskeleton proteins [BR:rtem04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     120943279 (PKD1) Ion channels [BR:rtem04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    120943279 (PKD1) Lectins [BR:rtem04091]  C-Type lectins   Others    120943279 (PKD1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PKD_channel Polycystin_dom PLAT Lectin_C LRR_8 Ig_3 LRR_4 K319L-like_PKD WSC GPS Y_Y_Y Motif Other DBs NCBI-GeneID:  120943279 NCBI-ProteinID:  XP_040212422 LinkDB All DBs Position 6:complement(25664222..25855562) Genome browser AA seq 4325 aa AA seqDB search MHCGNGQAGVRRKDGASPPVRALRVCPLFLLAAAAGLLLGLGSGAPPDTWCQPCPGNCTC DPPTCLVNCSGGGLQELDQVPGNVTVLDISNNNIETLNEELFEELQNLTEINLSDNPWLC DCRLSWLPRWANKSGISVVQADSTLCDRPHVASGQQLFNVSFSKYLCGSDLIYCPPSPST HSESVLIFVPSALTYANNETCSAQCYADLYNYWAVDSKHGCLCGVILPSNASLRCREVCG TPSLLSGCGLTIIQDVLRTESHTFLHASSDVYRLWEAVHLQVKSPIPVRNLRWNLGSQEF NLSQVFNTNEVSITHRYAQPGVYNVTVELRFGSRDLLLHEELRVVGIPEEVKLLGPSLVR TNETVDVHVMTRGGTDVEVQYIVTSQDDLAMSPTCPPGSVVYPSNNHCYQLISEKAGWFE AQKTCQDWGNGDMAVVSSLELQSFLKAHVTSGLEVWIGFNDSRSSESLPAGKRFDLESCQ NWLPGQPEPSQADRCVKMGPNGVCNTDLCSATHNYICEYKPQAVSLNAEYFAVGSLAFDR NWPLQNLTRVESALSSGEVEVLVFPGLHFSREVYISALEFITEEVQDPVQLRFQVYTQST EQDCPVQSTSSPPSSKPINETLPDCEEDLDSCNYTNSSIPVESGHFPASESKDATFSSMA QSNRSLPNFTLLKEYLFTIPAGNATQYLATFEDVSVPMLPNDLIVLQHDAPNKTFLHCHS SRSYYTFHQSDWVTCIPGHLVGEALINNTSCSLRVIGTTKELALIFSDQPNPGLWPPGKY TVTANFTNQLYEATQSYSFSVVSPVSGLSVIYPTPQDEIYYIPSDNPVVILKILSGSDVT SFWTGNNQTWSFSRTCPLNFFAVSTECSTDKGDISYSEVNLLGLGRGVVEVSITVQNEIS SQNISFLVKMEDPIRGLSASPYPQARVLLNTRVNNVASVESGSDVIFKWTVDDRSSFTYY NTVFNVIYQSAAVYKLTLTASNHVSNASVSYNVTVEKMNPMRDLKISSIPGIVTQDAPLQ LSASILIDSAVEVAFRWTFGDERQLDHNFRPPYNESVPDLPMHMVVVESSVTHTYQETGA YNVTLLVFNKHENMSKLISLQVQSILTNLTIETDAEVLVSGRMVSFQAAAEPSPFGVIYS WNLGDGTYYDNSSKSIVNHTYNNTGFFTVSIWALNDVSEKRVEKTFYVYEEITDLVVTSD EPTERGLQTFINASVESGDAITWRFDMGDGSILEGNEPMVNYTYSKDGNYTVNVTARNPV NSMSEILQVRVYVLQILKIEPSTCILENSNVTLTAHVTGDYQTYTFNWTFDNGSSSITVN GFPSVEYDFSNSGIFPLSLILSSHVNKAYYYTNICIEPQIINVTILPALQNVSLGNESLF EVIVFPLYQYRYSWDFGTNGSKYNGGTETSFVYKVPGVYQVTVSVFNNVSFHNGTAIVDV QEPIGALDIKHNGSEVLALDQVYLFEALGGGSKVEHHWDFGDGFTDKRQSVAHAYNSTGT FTINLYSYNSVSFNRTHLNVTVKTRIQGLTMNATRTIVPLNGSVTFSAFLQAGDNVRYSW ILCDRCSPIFCNSTISYTFRSIGTFNVIVTAENELGSLQDSIIIYVLEIIEGLQIITGDL VNDCCFPTNKSLPLQATVKDGTNISYSWFILKNDSVVQTGAGKTYQFTSLQPESYTFVLK AVNMLGNASVSMSVTFVESLGQVQLHACPNPVAINTTVNISMSLSSGSGVMYTWYLEESV VWFTYESFVLYNFLRPNPKEVFAIANNTLGLVNSTITIFVQEPVDGLSITSLDHKNDYVP TGTLVYLIGNVQRGTNVSWIWSIEDEHKKERSATVHFNRPGFYTVSLNASNDVSWEIAYK NFTVQDKICGLKLLVSKMVVEPGERVTFNVTMSAGTDVTYKLTINGDFSILLNGTSYTHD FTKIGGYPVTVVAHNQVSEDRVTVMISVLEAIENLKIVNCCEVALPARIEKSFRAEVSNG SLVAYTWQFDLQGHPPTSLAGRNVTYMPMAAGVLTIHLSASNALGSQNISKVIIIQELIV SVTLVPVKPFVNRSATFTAVVVPSPLDVRFEWTFGDDAFALVTYAATAKHTYLTPGDFVV KVNASNLIIFWIAEMTVKTQILECEEPEVQLELPTQVIMRRSQRNYIEAEFNLRGCVSYK TEYLWEIYKASSCLSYHESDKVHLLNVDMSRPQLVVPKLALDIGNYCFVFSVSFGDTPLS RSSFANVTMMPSKLVPIIDGGSYRVWSSSRDLVLDGKKSYDPNLEEDEQTPLTYKWSCTT LAKNLQNTVCSSDIMSELGEVSIHRSRLHPDVEYTFFLTVSKPGRHAESTNQTVLIKKGR VPIVSLKCVSCKAQSVYEVSASSYVYLEGSCTNCDDESRTGRWTAQSFSNKTLVLNATTT TTGDREMNLVLRQGVLKDGEGYTFTLHVSDPTMEEEGFASIDLLPNSPPFGGTCRIFPNE TIHALNTRVHFNCTGWRDTEDEVALVFILRAKRCRAGNCDDFWVYKGSRSEHSTFLPVGY NETNFVVELSILVQDQQGAIAVALNQSLVISMPKIPEGFQSIGHWLYNLTESALQGILKQ GDPQHVAEYSLALITVLNEYEQTVNKDEDIGKQNLGIVRKNITDALISLKVNTVDDIRQI ASALAQCTVASKELACASCQRKTLEKLEAMMSILQNETTQGMMTPTTIADNILNITGDVI QLVNTKSSVHKGGKLCGSLNNATVASEAYNLSSNLIRIMMKSRVLNEEPLTLQGGEILAR GKRSDPLNLLCYSNRTGCQFFIPQGFNSTFPDLTDIIQVMIQVDSNPYPFGFISNYTVST KVASMEFQTSNGSQIPVESLDSEKAITVSVANSTGVGNITAGVATIESRRSVKVDIEAES SNENAGLHIQLTYKVLDEWYSHMEKEPYIAAYLHETDHPNQYNYSAMKQITLDAMKGDDH KLYTFFIGPIKGNLTRHYYLNITNHYMWSSVDVTVGLYTSLCQYFDGTEMRWKTEGVQPL EDTRSNQAVCLTQHLTAFGASLFVPPHSVNFIYPPPPPGINYIVLLTCAVCFATYSIATI IVHKLDLLDVSKAGVIPFCGKAGVYKFEVLVKTGWGRGSGTTAHVGISLYGVDNKSGHRH LDGENTFHRNSVDIFQIATEKSLGNVWKIRLWHDNKGLSPSWYVQHVIIRDLQSGKSYFF LVNDWLSVGQEDSGRRVEKEIFAASETELKRFSRIFVAELQRGISEKHVWLSMWDRPPRS RFTRVQRATCCAVLIFLFLCANTVWYGVVGDRNHGDGAVSQVVPLSVDSVAVGLVTSVLV YPIYLFILFLFRRARSKTCVRPSLTYFDQNSLEIDNYLDNMLMESSFMTYTGIHGEGFSD QTKTEIIVDDTKGFIQWSANDGMLSWPDLLSDPTIMGNSIQKLEKHRSSQHLGLDGSCHP SEEDNVVLGLPPSMPRHFLASDGASSMSLPPELQRISRTETDLLSDLSNPFADKTETIML DKLNEKGQTITGPPREVKSIKSTRTVITDAFQRRGSMLPSWCTRVAHVLSCFLLFCCFGV SVWIGVGFTSSVGLMWLISGIFSFLFSFFVLEPLKVMAEALYFALVVKRLHPEEEDTLIE CPLVEHVSERITKVRPPQGFALFQAREEARKVKLLHKMLKNLVVYMLFFLVVLLTNYGDS SVNSSAYLLRRSIRQELASPRFLQIKRSEEFWAWASDVLLPYLGNIQRGSYSNLLGSARL RQIRLKKACRHGACPEEIEVFDDAGYDGGWLTSSQSWLHSPPDNTGAWYWGYLSFYDSSG YIQQLGVGLEENKAIIGKLQEDHWIDNLTRALFVEFSLYSPGVDLYSSVMLLLEFPLAGR TLPSVEIRAFPLLRLSSGPHLLLVMMVFLMMFVVYFVLSECLVIRKEGCQYFTHFWNYIQ WLMTVLSVCTVVMYLSRGSLADEQWDRYLKDRAAFLGLHQVAFLSSTFHSLSACVLFILT VKAAQQLRFIREWSMFGKTLGLSVRELCAAAGAVLGLLLVYAQLGFLLFSSSWERFHSFS SSALSLFSVARGAFSLKVPFPYSSCLHRLYFVSYQVLELWILVRFFAAILVNNYRHVRLD MFRPAFELQDYEMVELFLRRLRIWMGVSKVKEFRHKVRFEGMEPLPSRSSSETKSLRGST PSAASDTSSSSSFSTISSQLDTLSAISTRERAEVDANMQRLLPVLETLLSQFDLVNNATE EVYQIERSLEEVRGRAAKRRKHVKASTQKILCTTEVTTGLNRSFTTTKSRSSKSEPYPRV SKNSLAPRPSTVSQALENSSASKVITVDKVVTEEPALIPMQVSYTSQTKRRKSARAHNRV HPSVS NT seq 12978 nt NT seq  +upstreamnt  +downstreamnt atgcattgtggaaatggccaggctggagtccggaggaaagatggcgcctccccccctgtg cgggctctgcgggtctgccccctcttcctgctggccgctgctgctgggctcctgctgggg ctcggatcgggggcaccccccgacacatggtgccaaccctgcccgggcaactgtacgtgc gacccaccgacctgcctggtgaactgctccggaggaggactgcaagagctggaccaagtc cctgggaatgtcactgtgctggacatttccaataacaacattgaaaccttgaacgaagaa ctttttgaagaattgcagaatctaacggaaataaaccttagtgacaatccatggttgtgt gactgccgtctatcatggctccctcgctgggcgaataagagcgggattagcgttgtgcag gcggattctactctatgcgaccggcctcacgtggcctctggccagcaactctttaatgtc tctttctccaaatatctgtgcggatctgatctgatctactgtccacccagtccatcaact cacagtgaatctgtgttgatcttcgtgcctagcgccttgacttatgccaataatgagaca tgcagtgcccagtgctatgccgatctctacaactactgggctgtagactccaagcatggt tgcctgtgtggtgtcatcttgccctctaatgcctctcttcggtgtcgggaggtttgtggc actccatctctcctgtctgggtgtggtctcaccattatccaggatgtactcaggaccgag tctcacacctttcttcatgcctccagtgatgtgtacagactctgggaagctgtgcacctt caggtcaagtctccgatccctgtccgtaatctacgctggaatttggggagccaggaattc aaccttagccaggtattcaacaccaatgaggtgagcatcacccacagatacgcccagcca ggggtgtacaatgtgacggtggaactgaggttcggcagcagagatctcctcttacatgaa gagctccgggtggtgggcattccggaagaggtaaagctcctgggcccatccctggtcagg accaatgaaaccgtggatgttcatgtgatgactagaggaggaacagatgtggaagttcaa tatattgtaacatcacaggatgacttggcaatgtctcctacttgtccaccgggaagtgtg gtataccccagcaataaccattgttaccagctaatatcagagaaggctgggtggttcgag gcccagaagacctgccaggactgggggaatggcgacatggcagtggtcagcagtttggag ttgcagagttttttgaaggctcatgttaccagtggtttggaggtgtggatcggattcaat gacagccggagctctgaatccctccccgcggggaaacgctttgatttggagagctgccag aattggctccctggccagccggagccgtcccaggcagatcgttgtgtaaagatggggccc aatggagtgtgcaataccgacctgtgcagtgccacacacaactacatctgtgaatacaag ccccaggctgtttctctgaacgcagaatactttgcggtgggatctttggcgtttgacagg aattggcctctacaaaatctaacaagagtggagagtgctctgtcttctggggaggtggag gttttggttttccctggtttgcacttttcccgggaagtgtacatatcggctctggaattt ataaccgaggaagtacaagaccctgtgcagctgaggttccaggtgtatacacagagcaca gaacaagactgtccagttcaaagtacaagctccccaccaagcagcaaaccaataaatgag actctccccgactgcgaggaagacctggattcctgcaattacaccaacagtagtattcca gtggagagtggccatttcccagccagcgaatctaaagatgccaccttttcatcaatggcc cagtccaacagaagccttccaaacttcaccttattaaaggaatatctcttcacaatccct gctggaaatgccacacagtatttggcaacgtttgaagatgtaagtgttccaatgctccca aatgaccttattgttctacaacatgatgcccccaacaaaacgtttctacactgccactcc tctagatcatactatacattccaccagtcagattgggttacctgcattcctgggcacctc gttggagaagcacttatcaacaacacatcatgctcattaagagtcattggcaccaccaaa gagcttgccttgattttcagcgatcaaccaaaccctggtctgtggcctcctggaaaatat acagtcacggcaaactttaccaaccagttgtacgaagctacgcagtcttacagctttagt gtggtgtcaccggtttctggtctgagtgtcatctatccaacaccacaagacgaaatctac tacattcccagtgacaatcccgttgtgattctcaagattctctcaggctccgatgtcacc tcattttggactggcaacaaccagacatggagcttcagtcggacgtgtcctctaaatttt tttgctgtatccacggaatgttcgacagataaaggagacatttcatactctgaggtcaat ctgctcgggctggggagaggggttgtggaagtttcaataactgtgcaaaacgagataagc tcccaaaatatatcgtttttagtgaagatggaggacccaatcagaggactgagcgcaagc ccttaccctcaagccagagtgctgctcaacacccgagtgaataatgttgcttctgtggaa tccggatcagacgtgatctttaaatggactgtggacgaccgctcatcttttacatattac aacaccgtctttaatgtgatctatcagtctgccgctgtttacaagctcacattgacagct tcaaaccatgttagcaatgcttcggttagttacaacgtgactgtagaaaagatgaaccca atgcgcgaccttaagatctccagtatcccaggcattgttacccaagatgctccgttgcag ctctccgcaagcatacttatcgactctgcagtggaagtcgcatttcgatggacatttgga gatgaaaggcagcttgatcataattttcggcctccctataatgagtctgttcctgacctg cccatgcatatggtagttgttgagagtagtgtcacccacacctaccaagaaacaggtgcc tataatgtgacactgttggtgttcaacaagcatgaaaatatgtcaaaactgatctctctc caagttcagagcatcttgactaacttaaccattgaaacagatgccgaggtcttggtcagt ggcaggatggtcagttttcaagcagcagctgaaccctctccatttggcgtcatttactca tggaacctaggtgatggtacttactatgacaacagcagcaagtcaattgtgaaccatacg tataataacacaggattcttcactgtcagcatctgggcactaaatgatgtcagtgaaaaa agggttgagaagactttttatgtctatgaagaaattactgacttagttgtaacatcagat gagcctactgaaagaggtttgcagacattcattaatgcctcagtggaaagtggagatgct attacatggagatttgatatgggagatggttctattctagagggtaatgagcctatggta aactatacatactcgaaagatggtaactatactgttaatgtcactgcacggaatccagtg aactccatgtctgagattctccaagtgcgggtgtatgtcctacaaattcttaagatagag ccttctacttgcattttggaaaattcaaacgtcactctgaccgctcatgttacaggagac taccagacttacacttttaactggacatttgataatggttcatcaagcatcactgttaat ggattcccatctgtagagtatgacttttcaaacagtggaatttttcctctttccctaatt ctctcaagccatgtcaacaaggcttactactataccaacatctgtatagaacctcagatt atcaatgttacaatactgcctgctctacagaatgtaagtttaggtaatgagagtttgttt gaagtgattgtcttccctctctaccagtacagatacagttgggactttgggaccaatggc tcaaagtataatggtggaacagaaactagttttgtgtataaagtccctggagtatatcag gttacagtgtccgtgttcaacaacgtatcttttcacaatggaacggcaattgtagatgtc caagaacccatcggagcactagatatcaagcacaatggaagtgaggttttggcactagat caagtgtacttatttgaagccttgggcggtgggtcaaaagttgaacatcactgggatttt ggcgatggctttacagacaaaagacaatccgtagcacatgcttataatagtactggcacc tttactattaatctatatagctataatagtgtaagttttaatcgaacacatttgaatgtc acagttaagacaaggattcaagggctgactatgaatgccaccaggacaatagtgccttta aatggctctgtgaccttctcagccttcctacaggcaggggataatgttcgatactcgtgg atattatgtgatcgatgctcgcctatattttgcaattccacaatttcttacacttttcga tctattgggacttttaatgttattgtgacagctgaaaatgaacttggctccttgcaggat agtatcatcatctacgtcttggaaattatcgaaggactgcaaatcatcacaggggacttg gttaatgattgttgtttcccgaccaacaagagtctgcctctccaggccacagtgaaggat gggacaaacatctcgtacagctggtttattttgaaaaatgacagtgtagttcagactggt gctgggaagacctaccagttcacaagtctacaaccagaatcttacacatttgtcttaaaa gctgtaaacatgttgggaaatgcaagtgtatccatgagtgtaacttttgtggaaagcctt ggtcaagttcagctccatgcttgtcctaacccagttgcaatcaataccacagtcaacatt agcatgagtctgagtagtggttcaggagtgatgtacacttggtatctagaagaaagtgtg gtgtggttcacatatgaatcttttgtcctttacaatttcctacgtcctaatccaaaggaa gtgtttgccattgcgaacaacactttaggtttagtcaactcaaccatcaccatctttgtt caagagccagttgacggtttgagcattacaagcctggaccataaaaatgattatgtacca actggaactcttgtgtaccttattggcaatgtgcaacgtggtaccaatgtgtcgtggatt tggagtattgaagatgagcacaagaaagaaaggtcagctaccgtgcactttaatagacct ggattctatactgtcagcctgaatgcatccaatgatgtaagctgggaaattgcctataaa aattttactgtccaagacaaaatatgtggtttgaagctgctggtgagtaaaatggtggtg gaacctggtgagagagtcacatttaatgtcaccatgtcagccggtactgatgtaacctat aaattgactattaatggggatttctccattttacttaatggcactagttacacccatgac ttcacgaaaatcggtggctatcctgtgactgtggttgcccacaaccaagtgagtgaagat cgggtcacagtcatgatttctgtgcttgaagcaatagagaatctgaaaattgtaaattgc tgtgaggtggcgttaccagccagaattgaaaagagcttcagagcggaggtcagtaatggc tccctggttgcttacacttggcagtttgacttacagggtcatccgccaaccagcttagca ggcagaaatgtaacctacatgccaatggctgcaggggtgcttacaatccacttgagtgca tctaatgctttaggaagtcagaacatctccaaagtaatcataattcaagaactgattgtc agtgtcacattggtgcctgtcaaaccttttgtcaaccgaagtgcaacttttactgctgtt gtggttcctagccccttagatgttcgttttgagtggacatttggggatgatgcctttgct ttggtgacatatgctgccactgccaaacatacctacctaaccccaggagactttgtggta aaggtcaatgcctccaatctgatcatcttttggattgctgaaatgacagtcaaaacccag attttagaatgtgaagagccagaagttcagctggagctaccaactcaagtaatcatgagg aggtcacaaagaaattatattgaggcagagtttaatttgcggggttgcgtcagctataaa acggaatacctatgggagatttataaagcttctagctgcctaagctatcatgagtcagac aaagtgcacctactgaacgttgatatgagcagacctcagcttgtggtgcctaaactagcc cttgatataggaaactactgctttgtcttctctgtgtcttttggagacacgcccctctct cgaagcagctttgcgaatgtgactatgatgcctagtaaattggtgcccatcattgatggt ggatcttatcgtgtttggtcaagtagtcgggacttggttttggatggaaaaaagtcttat gacccaaacctagaagaagatgaacaaactccactgacttataaatggtcttgtacaacc ttagcaaagaatttgcagaatacggtttgcagttcagacatcatgtctgagctcggtgaa gtgtctatccataggtcaaggttgcacccagatgtggagtacacattttttctgactgtc agcaagcctggaagacatgccgagtccaccaatcaaacggttttaataaaaaaaggcagg gttccaattgtgtctcttaaatgtgtctcctgtaaggcacagtctgtgtacgaagtgagt gccagctcctatgtttacctagaagggtcctgcaccaactgtgacgatgaatccaggact gggaggtggaccgctcagagcttcagcaacaagactcttgtcctcaatgccaccaccacc accactggagaccgggagatgaacctagtgcttaggcagggagtgttgaaggacggagag gggtacaccttcactcttcatgtcagtgatcccacaatggaggaggaggggtttgcttcc attgatctgctaccaaacagccctccatttggaggaacatgtagaatcttccccaatgaa accattcatgctctgaacacacgggtccactttaactgcacaggttggagagatacagaa gatgaggtggccctagtgttcattctgagagctaaacgttgccgggccggtaactgtgat gacttctgggtgtataaaggcagccgatcagagcacagcaccttcctgcctgtcggctac aatgagaccaactttgtggtggagctttccatactagtacaagaccagcagggggcaatt gccgtggccttaaaccagtccctagttatttccatgcctaaaatcccagagggcttccaa agtattggtcactggttgtataacctaacagagagcgccctgcagggtatactgaaacag ggagacccccagcacgtggctgagtattccttggctctcataacagttctcaatgagtat gaacaaactgtgaacaaagatgaagatattggcaagcagaacttgggaattgtacgcaag aacatcacagatgcccttatatccctgaaagtcaacaccgtggacgacatacggcagata gcctctgcactggcgcagtgtacggtggccagtaaggagctggcatgtgcatcttgtcag cggaaaactctagagaagctggaagccatgatgtctatccttcagaatgagaccacgcaa ggaatgatgactcctaccacaatcgcagataatattttgaacattacgggagatgtcatc caacttgtaaataccaagtcatcagtccacaaaggaggcaagctgtgtggtagtctgaac aatgccacagtagcctctgaagcttacaatctgtcctccaacctcataaggatcatgatg aagtccagagtgctgaatgaggagcccctgaccttacaaggaggagaaattctggccaga ggcaaacggtctgatccacttaacctgctctgctacagtaacagaacaggctgccagttc tttatacctcagggctttaatagcaccttcccagatttaacagacattatccaggtcatg atccaagtggactccaacccttacccctttggcttcatcagcaactacaccgtctccacc aaggtagcctctatggaattccagaccagtaacggcagtcagatcccagtggaaagcctg gattctgaaaaggcaatcacagttagcgtcgccaatagcactggtgttggcaatatcaca gcaggtgtggctacgattgagagccgccgctcggtgaaagtggacattgaagcagaaagc agtaatgagaatgcaggccttcacattcagcttacctataaagtcctggacgagtggtac tcccacatggaaaaggagccgtacattgctgcctatcttcatgagaccgatcatcccaac cagtacaattacagcgccatgaagcagatcacattggatgctatgaagggagatgaccat aagctgtacacgttcttcatcggtcccataaaaggaaacctgaccagacactattaccta aacatcaccaaccattacatgtggtcctctgtggatgtgacggtgggactgtacacctcc ctgtgtcagtacttcgatggtactgaaatgagatggaagacagagggagtccaacccctg gaggacacccgttctaaccaggctgtctgtctgacccagcacctcactgcctttggtgcc agcctcttcgtccctccccactccgtcaactttatctaccctcctccgcctcccggaatc aattacattgtgcttctgacatgtgccgtctgctttgccacctactccatagccaccatt atcgtccacaaactagacctcctggatgtcagcaaggccggggtcataccgttctgcggg aaggctggcgtctataaatttgaggtcctggtgaaaacgggctgggggcggggatcaggc accacggcccacgtaggtataagcttatatggagtggataataaaagtggacacagacat ctggatggtgaaaataccttccaccggaacagcgtggatatcttccagattgccactgag aagagcttgggaaatgtgtggaaaattcgcctatggcacgataacaaagggctcagtcca tcttggtatgtgcaacacgtcatcatccgagacctgcaaagcggcaaaagctacttcttc ttagtcaatgattggctgtctgtaggtcaggaggacagtggccggcgggtggagaaggaa atctttgctgccagtgagacggagctgaagaggttctctcgaatttttgtggcagaactg cagagaggaatttcggagaaacacgtctggctgtctatgtgggaccgcccgccacgtagc cgcttcacccgcgttcagagagccacctgctgtgctgttcttatcttcctcttcctgtgt gccaacacggtgtggtatggcgttgtgggagatcggaatcatggggatggtgccgtgtct caggtggttcccctcagtgtggactcggtggctgtaggattggtgacaagtgtcttagtc tatcccatttacctgttcatcctcttcctattcaggcgagctcgcagcaagacctgtgtc aggccgtccctcacatacttcgatcagaactccttggaaatagataactacctggacaat atgttgatggagagttcttttatgacatatacagggatacatggagagggattttctgac cagaccaaaacagaaataattgtggatgacacaaagggtttcattcagtggagtgctaat gatggtatgctcagctggccagacctactaagtgacccgaccatcatggggaacagcatc cagaaactggagaaacaccgcagtagtcaacaccttgggttagatggcagctgccatccc agcgaggaggacaatgtggtactaggccttccgccatccatgccacgccatttcttagca tcagatggagccagcagcatgtctctccccccagagctgcagaggatttcccgtacagag acggatcttttgtcagacctgtcaaacccttttgcggataaaacagaaaccataatgctg gataaattaaacgaaaaaggccaaaccataactggacctcccagagaagtcaaatctatc aagtcaaccaggacagttatcacggatgccttccagagacgtggaagtatgttaccctct tggtgcacccgtgtagctcacgtccttagctgctttctcctcttctgctgcttcggggta tctgtgtggattggggtcggcttcacctccagcgtaggcctcatgtggttaatatctgga atattcagcttcctcttctcattctttgtcctggaacctttaaaggtgatggcagaagcc ctgtactttgctttggtggtgaagcgtttgcaccctgaggaggaggacactcttatagag tgccccctggtggagcacgtctccgaaaggatcaccaaggtccggcccccgcagggcttt gctcttttccaggccagagaggaggctcgcaaggtgaaactgctgcacaagatgctaaag aacctggtggtgtacatgctgttcttcttggtagtacttctcacaaactatggtgattct tctgtgaactccagtgcttacctgctgcgacgttcaattagacaagagctggcgagtcca agattcttgcagattaaaagatccgaggagttttgggcctgggcatcagatgtcttgctg ccatacctgggcaacatccagaggggaagctacagcaacttgctgggatctgctcgttta cgccagattcggctgaaaaaagcatgcagacatggcgcatgtccagaggagattgaggtc tttgatgatgcaggttatgatggcggctggctcacctcttcccagtcttggttgcactct ccacctgataataccggagcctggtactggggttacttgtccttctatgacagctccggg tacattcagcagttgggtgttggtttagaagaaaacaaggctatcattgggaaactccag gaagaccactggattgataatctgacgagggcgctgtttgttgaattctcgctgtacagt cctggggttgacctgtactcctcagtgatgcttcttctggagttccctttggcgggtaga actcttccatctgttgagatccgtgccttcccattactgcgcctaagcagcgggccccac ctccttctggtcatgatggtctttttaatgatgtttgtggtgtactttgtcctctctgag tgtctggtcataaggaaggagggatgccagtacttcacccacttctggaactacatccag tggctgatgacagtattatcagtgtgtactgtggtcatgtaccttagtcggggcagcctg gctgatgaacagtgggaccggtacctgaaggacagagctgcattccttggtctccatcag gtcgcattcctgagctccacctttcacagcttgtctgcctgtgtccttttcattctaact gttaaggccgctcagcagctgagattcatccgagagtggtccatgtttgggaagacactg ggcctgtctgtaagggagctgtgtgctgcagctggggcggtattaggactgctactggtg tacgctcagctaggatttttgcttttctcctcctcctgggaacgttttcacagtttcagc tccagcgctctctcacttttctctgtggcacgcggtgcttttagtctgaaagttcctttt ccgtattcatcctgcttacaccgcctttactttgtgagctaccaggtcttggagctgtgg atcctagtgaggttctttgcagccatcttggtcaacaactaccgtcatgttcgactcgac atgttcagaccagcattcgaactgcaggattatgagatggtggagctttttcttaggaga ttacggatatggatgggtgtcagcaaagtgaaagagtttcgtcacaaagtgaggttcgaa ggtatggagcctcttccttcacgttcctccagcgaaacaaagtcacttagaggttccact cctagcgctgcttctgacacctcctcctcttcatccttttccaccatctccagccagttg gacactttgagtgccataagtaccagggagagagcagaggtggatgccaatatgcagaga ttgctacccgtgctagaaaccttgttgtcccagtttgatttagtcaacaatgccacagag gaggtgtatcaaattgagcgaagcctagaagaagtacggggaagagcagccaagagaaga aaacatgttaaagcttcaactcaaaaaatattatgcaccacagaagtgaccacaggtctc aaccggagcttcaccacaacaaagagcagaagctctaagtcagaaccctacccaagagtc agcaagaactctttggctccacggccatccacagtttctcaagccctagagaacagttca gcaagcaaagtcatcacagtggacaaggtggtgacagaagaaccagctctcattcctatg caagtatcgtacacttctcaaaccaaacggagaaagtcagcgcgggcccacaacagagtt caccctagtgtcagttag

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