Rana temporaria (common frog): 120945544 Help Entry 120945544         CDS       T07929                                  Symbol HMCN1 Name (RefSeq) hemicentin-1 isoform X1   KO K17341   hemicentin Organism rtem  Rana temporaria (common frog) Brite KEGG Orthology (KO) [BR:rtem00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:rtem04990]     120945544 (HMCN1) Domain-containing proteins not elsewhere classified [BR:rtem04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    120945544 (HMCN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 TSP_1 VWA_4 C2-set_3 EGF_CA V-set_CD47 G2F TSP1_spondin cEGF C1-set GBD_Hemicentin Ig_VEGFR-1-like_5th Sp38 TSP1_ADAMTS EGF_3 FXa_inhibition TSP1_CFP_C TSP1_CCN Fibulin_C EGF VWA_2 hEGF Motif Other DBs NCBI-GeneID:  120945544 NCBI-ProteinID:  XP_040215726 LinkDB All DBs Position 7:complement(100945342..101329494) Genome browser AA seq 5518 aa AA seqDB search MSISQESEIRRNVRMLFFRNFSIQLPIVLLLLQLLQLNSCAESEPDIGKTPDGASTLAFV FDVTGSMYDDLVQVIDGASKILETSLNRQKKPLYNFALVPFHDPEIGPVTITTDPETFQN ELKELYVQGGGDCPEMSVGAIKIALEISLPGSFIYVFTDARSKDYQLASDVLQLIQQKQS QVVFVLTGDCDDRGHVGYKVYEEIASTSSGQVFHLDKKQVKEVLKWVEETVQASKVHLMS TDHSSEASFTWEIPFDPSLKEVTVSLSGPAPDIELYNPLGRQMKPETGLNELLNIYNSAK VLNIKEPIPGMWKIKTSSSARHSVRITGVSTVDFQAGFSNKPTLDFSKTSSRPIEGILTY VLLNTTGLQHPARIDRLDLLTISGKLLESIPVKYYPDKIPYEIWNVTEFIPPNEAFILRI TGYDKDDYLFQRASSVSFSNIIPGVPKVSMPEVTPGYYLQLGHIPCSVESLIPITLHFSK NGVRLGPEQKFRESVNTSWVIANVSSLDEGYYDCFVTSSAGSGRARTFLDVNEPPPVIKA SNNITINIGKQAILSCNVLSTVSYNLTWLRNKLDLRQASVSGIQVLSNNSLKIISVDITD AGEYICFASNEGGTAAASVILTVQDPPKVLVEPKNETFTKGLRIKLKCSATGFPVPQIVW THNDMFLTYSSRYVITEDGSFIIKNAVEKDSGIYTCLAANNAGTDRQTSKLTYIEAPVVT VFRKEMLIAVDTEANIECKATGIPEPQFDWYKGDVKLSTSSHISIDHIHGTLAIKSTQYI NAGEYTCEARNEAGKSSGKVTITVGAAPVFTQSPSDIAIDIGSNVILPCSVQGFPEPKIK WSKLTGTTASSKPLVPQQKTGALKITNLWVGDEGTYICEAENQFGKIQAQATVTLTGLVI PVIGESPPVVNVIEGNQVTLPCILLAGNPLPVRQWLRNNEVLISSPYVSIRSDGTLHLES VHLKDSGEYICVATNVAGTSRRVTAVNVHVIPVIKHGPQIFSTVEGNAISLPCKASGVPT PSIIWKKKGENVVPNNGTILIDSDGSLFLSTPHGEDSGEYSCSAINAAGYATRKVQLTVY VKPRILNTGSSSLQDGFKGQIEISAKVSDDVVLPCEVKSVPPPFITWAKETQLISPFSQR HTILPPGSMRILDVRVTDAGTYTCVATNIAGNVTQIVTLNVYAPPKIQRGPQMIRIQVKQ SFEIACISQGIPPPRTAWFKDGRMLTLDEKLQHFTIRVASAELSDAGVYTCIASNMVGQD SANVTIEVQAPPTLSDLEPPYDKTHQERLSSQQVAFPCPAKGNPKPVIKWLRNNKELSGT EPGIKIAEDGTLLIISSLTSYDNGEYKCVASNQAGLTERKYNLKVHDPPAIKDKEKLTNV SVLLSHDTNLFCDATGSPPPFITWYNGSTQVIESDNIKILEKGRILKIMKTTLSHSGSFS CTASNIAGSDEKHFFVDVLEPPEIAGRGTVDDISVIIGRAAKLKCEVKGKPYPAIQWFKD NRLVGGGDTNVNILENGQTLYIKNSRLTDSGQYKCVATNSAGLQTKESKLVVNVPPSIKN ENTTTELSFNVDSRVSLECDVWGIPHPAITWYTDGKRIQASTHISFIENGKYLHISEVKV THSGKYKCYATNSAGHAEREYLLDVYAPASIHKDLSKPQTTKVIVGKTLVLECEATGHPL PLITWLKEGVPIQISDNIRLLYNGKKLEIKSTVESDQGQYICVATNLAGKSEMIYNVHIL VPPTIEDIDDPGEYTVIASNPVELECYIKGIPLPAVMWLKNGIPLEPSNDLHIQDKGQKL IISSSGSSDSGVYECVVKNEAGTSRKIFNVNVHVLPSIKPEPSPLSVVMRKPIILQCIAT GIPSPQITWLKDGLPFNIIKENISVESFGRILHFKSTMTDDAGKYSCVASNAAGEAEQSI WLNVYEPPKIENSDEVHHETILGNQSVRLECKASGNPDPVVTWLKDNHPLTIVDNILLSN QGQVLQITNAKIHNAGVYKCVASSLVGTAEMTYVLQVHVLPSIFGNNDPVSVIVNKPVRL ECEATGFPAPSLTWLKDGIPVSSISGGIQILSGGRVLMLANTRIGDAGKYTCVAVNAAGE HQKDFDLSVYVPPNIMGEQQNITILMGQKLSLKCESNAIPPPVLMWFKDWRPLVNRPGLG ISESGQFLEIENAQVKDTGRYSCEAVNIAGRTQRNFNVNILVPPTIKDSEEESDVTVIEG TLISLVCDSSGIPPPALTWKKNDTPVTPDSKGRIRFLSGGRHLHIAVAMESDASSYTCTA SNTAGNAAKKYNVKVYVHPSISGGGPAPLDVVVIEENNVTMECDPSGSPQPMLTWLREGI PLNNGDGLKILRNGRQLHLEKAQASDSGLYLCVAVNVAGQADKKYDLKVFVPPRILGSFE EHENVSVVERNPVTLTCEVSGIPPPKITWFKDGQPIHPNNTPQVMSGGMTLRFVHTALSD AGRYKCVVSNAAGVKNKEFHLNVLVPPRLTGNVLEDIKVKEKSDVVLSCEATGNPVPQIT WLKDGQPLQEDTHHRIKDGGQHFQIISAMETDTGRYTCIVSNLAGDKSRRFSLAVMVSPI ISGAKPKESPEDISVIQDSSVLLACEVHSIPTSTIVWYKDGQQIHSKDNIRILPGGHTLQ ILKAHEDNFGKYSCIAANEAGVAEHHYNLKVYTPPRITKDNLAGTGYLSKQIKAKVGTNI SLECNVQAFPVATVRWYKDGQPLDPRSLIVNGNKLNIDKADLSDTGRYTCVASNVAGEDE LDFDVNIQVPPNFPKLSSLLLNTDSSIVERIGERKDVIVNNPFTLYCETNAIPPPTITWY KDGKVLTSSDKTFLSPGGHSLQIARARMEDAGTYSCVAVNEAGEDSLQYNVRILLPPTFE GGSENLSEDVSFLANQTVLLDCVGESIPAPTVSWQKDGQAIKDGKHYQILSDGRYLQISN AELSDTGRYICIVENVAGSAQKLFKLNIYVPPKVTGDAFENVTAIENDFISLSCDVTGFP PPAINWIKDGNVLSSSKHLLIVPGGRVLQIPQMKLTDAGDYVCVAINQAGESKKTFYLSI FVPPTIIGSGRDSSTEVNINIATSASLECFTNAVPPAVINWYKNGQMLLESTNYIILDEG QIMKIKNAQVSDTGEYECVATNVAGQDKKTFLVNVYVPPSIQGPQVEYNNGIIENSVTLH CNAYGIPPPTITWLKDGNPINYSDSLEILFLSGGSIMKITRAQLTNSGNYTCLASNIEGS THKTFILAVQVPPSITGSGTSNEVNALPDDDVQLMCKTRGVPTPVVHWSKDGQPINTDDR LNIRKIDNGEILSIPKVQRADMGKYTCVAINLAGEDDRIFHLNVYVPPKIADNEETVSIA AALETSVNIECFVTGDPTPQINWLKNGLPLPVSSQIRPLSSGKILRISRLQKSDEGFYTC VASNRAGVDKKKYNLKVYIAPTMDGSDITEELTTIKGNPTTMRCIADGYPEPHISWLRNG KYIDLVPNKGTTFHILNTEITDIGRYTCTATNEAGSISKHFILNVLEPPHINGSRYIDEL SVTINNQVELVCYTTGFPSPLINWLKDGQLLSQTENVHFIKGGQILQITSAQEENVGLYT CLASNNAGNTKKEFSVKVHMPPNIAGINGIHNITSLKDKQVTLECKSDAVPPPEITWLKD NKPLLPSVRIHIESDGRFVHINSAEVEDAGHYICIARNIAGKTTREFILNIYVPPTIKDG PNLVTSFVNNPANLECKAAGVPLPRISWRKNGAILHENNERYTVMESGTLYFPSANVTDS GLYTCLAANAAGSNQKQTKLLVYDPPLINSGSTNITTIVNNEITLNCEVTGTPKPTVEWK KNGLLINTNMNYNIYRFLSSGSLIIISTAVEDTGMYVCFASNDAGHDEIAIYLSVLVPPS IADEVTNIFINKLSSSIIPCTTYGVPQPVVHWLKDGIRLPAVGESYKILSSGSIEIPRTD LTHTGRYSCKAINEVGSAEIHINLYVQEVPVIYSQGDYFEATVNNSITLSCEALGTPSPT ITWQKEGVGIKTGGHFTMFINGNLNIAYVTQEDGGTYTCIAQNPAGTALGKIKLKVLEPP LIKPHKKEYTVVVDEPVTMICEAFGNPMPEIAWHKNGAPLSKSAVQRIIGTGALQIGYAQ PDDAGLYTCTAENAVGSMSSSMNLSVLVPPQIQKKINELFVIQSFPVTIPCNTYGIPTPS IAWTKNNVSIADNSEKYAVTKSGDLILRQTEHHDMGNYTCTASNIVGKDSHTISITIQYG PSFTELPSDVSLNKEEKLRLTCKATGNPRPQITWTFKHKSTPVQIGQSKYLNDFVIERVS KEDSGTYTCIAENIVASINTTVKVFVKEPPVLVGFHHTNLTAALGGSIILNCIVQGNPIP KIQWNKKENDIPFNRRFKQFNNGSLAIYNTTNEDIGDFICIATNDAGTMGHTVTLSLQKP PIIKSPPVDMTVNAGTSVVLNCQAEGEPVPDIFWSRLTRPISGDSRFSILSNKSLHIVAV RKEDTSVYECRATNVMGSAVAKSSFIVQVHGGFSEWLPWQSCSVTCGQGIQKRMRLCDNP APANGGLYCQGEESETRLCQNKPCPADASWLDWSPWEECSKTCGSGKQTRTRICNIPPAQ EGGKTCDGKAIDTKVCNIKSCPVDGEWSSWQVWGPCSKTCGKGTQIRARLCNNPPPSFGG TFCEGQDTQSQICNIRHCPVDGKWSPWGSWTPCSVSCNGGLRQRTRECSSPQPQYGGHKC KGKAFENEFCNGDSCPIHGNWGPWSAWETCSRTCNGGQRRRHRTCDSPTPSHNGRGCAGK DTEIHKCNTEICPADSNWGPWEAWSKCSVSCGGGQQIRTRICKHPVRSNNGRTCPGDSTQ LLRCNVQGCQGGVQSVRGTLSGTINDVDLHIAQLNGSVSNNSESHASTIKATFTNIPKSL GSSMRNLASLLDPIYWTVAKERGEAVNGFTLTGGEFIRETQVEFATGEIMRITHNSRGLD ADGFLLVDTVVKGYIPQLPISTNIKLKGYTEDYVQTGLGQLYAYSTRMFYLDEVSVPYTW NHTVSYDPSHGKMPVMLETLHVSSIGADYNPLEETLSFQMHAFISKGDIDDQCPPGFSYD ISGLYCADDDECAINSPCTQSCHNIMGSYYCSCPKGFMTSPDGRTCLDIDECTLEESVCR KNQECKNSIGSYICVLKCGTGFTAAPNGLECQDINECKESNPCHQRCFNTIGSYRCGCDP GYHLKGRSCFDLNECHQNVCRPDQLCRNTRGSYKCIDICPIGFTKAENGSCVDIDECRDS SHRCKSNQICENTQGRYLCVCPRGFKSEGPGKPCKDVNECEKQDVCQHECRNVLGSYQCL CPTGYQLMANEKTCQDIDECLVHNIHCGVNQMCFNMRGSHQCIDTPCPPNYVRDSSGYCL KNCAPNDLECALSPYALQYKLVSLPFGIAANQDLIRLVAYTQDGILHPRTTFLITDEDST VPFSIREENMKGVVFTNRPLKEPETYRMKVRALSYSTDRTIEYQTTFIVYISVSPYPY NT seq 16557 nt NT seq  +upstreamnt  +downstreamnt atgtcaataagtcaagaaagtgaaatcaggaggaatgttaggatgcttttctttaggaac ttttctattcagttgccaattgttctacttctgcttcaactactccaactaaattcctgt gcagaatcagagccagatataggaaaaaccccggacggagcttctactttagcatttgtt tttgatgtcactggatccatgtatgacgacttagttcaagtgattgacggcgcatcaaag attttagaaacatctttaaacagacagaaaaagccgctgtataattttgctctggtgcca tttcatgatccagaaattggccctgtcacaattacaacagatccagagacatttcagaat gaacttaaagaactctatgtacagggaggaggagactgtcctgagatgagtgtgggtgct attaaaattgcattggaaatatctctgccgggatcttttatttatgttttcactgatgcc agatccaaggactaccagcttgccagtgatgtgctacaactgatacagcaaaagcaatct caagtggtgtttgtgctcactggagactgtgatgacagaggccatgtggggtacaaggta tatgaagaaattgcttccaccagctctggtcaagtatttcacctagacaagaagcaagtt aaagaggtattgaaatgggtagaagagactgttcaagcttccaaggttcatcttatgtcc acagaccactcgagtgaggcatcattcacctgggaaatcccctttgatccaagccttaaa gaagtcactgtgtcactgagtgggccagcaccagacattgaactgtacaatccattgggg agacagatgaagccagaaacaggtctcaatgaattactgaacatatacaattctgccaaa gtcttaaatatcaaagaaccaataccggggatgtggaaaattaagacatcaagcagtgca cggcattcagtgagaatcacaggtgtcagtacggtggatttccaagcaggattctccaat aaacctacattagatttcagcaaaacttccagcagacccatagaaggcatccttacatat gtgcttctaaatacaactggattgcagcatccagctagaatcgatcgtcttgacttgctg actatctcaggaaagcttctggagtccattccagtaaaatattaccctgataagataccc tatgaaatatggaatgtaactgagtttattccaccaaatgaagcattcattttaagaata acaggatacgataaagatgattacttgtttcaacgggcatccagtgtttccttctcaaat attattccaggagttccaaaagtgtcaatgcctgaagtaactcctgggtattacttgcag cttggtcacattccatgctctgttgaaagtctcatacctataaccttgcacttcagtaaa aatggggttcgacttggtccagaacaaaagttcagagaatcagtcaatacaagttgggta atagccaatgtctcttcccttgatgagggctattatgactgttttgttactagcagtgca ggaagtggacgagcccggacatttctagatgtaaatgaaccaccacctgtaattaaagct tcaaataatatcaccatcaacattggaaagcaagcaatattgagttgcaatgttttaagc accgtcagttacaatttaacatggctgagaaacaaacttgatttacgtcaggcaagtgtt tcagggattcaggttctgagtaataactctctgaagataataagtgtggatattaccgat gcaggggagtatatctgctttgcatcaaatgaaggtggaacagctgcagcttctgtaatt cttactgtacaagacccacccaaagttttagtagagcccaaaaatgaaacatttactaaa ggacttagaattaagctgaaatgctctgcaacgggattccctgtgcctcagattgtttgg acccacaacgacatgttccttacgtactctagcagatatgtgataactgaagatggcagc tttattattaaaaatgcagtggaaaaagattctggaatttacacatgtctggctgctaac aatgctggaacagatagacagacatccaaacttacttacatagaggcccctgtggtgaca gttttcagaaaagaaatgttaatagcagttgataccgaggcaaatatagaatgcaaggca acggggattccagagccacagtttgattggtataaaggagatgtaaagttgagtacatcc tcacacatttctattgatcacattcatggaacactagcaattaaaagtacacagtatatt aatgctggggaatatacttgtgaggcaaggaatgaagcaggaaaatcaagtggaaaagta acaattactgttggtgctgctcctgtgttcacacagagccctagtgatatagcaatagat attggatcaaatgtaattttgccttgttcggtccaaggattcccagaaccaaaaataaaa tggagtaagttaactggaacaacagcatcatcaaagccacttgtaccacagcagaagact ggagcactaaagattaccaatctgtgggtaggagatgaaggtacctacatctgtgaagct gaaaatcaatttggaaaaatccaagcccaggccactgttacattaactggactagtaatt cctgttattggtgagagccctcctgtggtcaatgttatcgaaggaaaccaagttacattg ccatgcattctgttagctgggaatcctcttcctgtgaggcaatggctcaggaacaatgaa gtattgatctccagcccatacgttagcatacgttctgatggaacccttcatcttgaaagt gttcatttaaaagacagtggagagtatatatgtgtagcaacaaatgttgctggtacaagc agaagagttacagctgttaatgtacatgttattccagttataaaacatggaccacagata ttcagcacagttgaaggaaatgcaatatctttgccatgcaaagccagtggagtccctaca ccatcgattatttggaaaaagaagggtgaaaatgttgttccaaacaatggcactatattg attgactcagatggaagtctgttcctgtctactccacatggggaggattctggggagtac tcctgcagtgcaattaatgctgctggttatgcaacacgtaaagttcagttaacagtttat gtaaagcccagaatcctaaatacaggatcatcgagtcttcaggatggctttaaaggtcaa attgagatatcagcaaaagtgagtgatgatgtggtgcttccttgtgaggtcaaaagtgtt cctccaccatttattacctgggccaaagagacacaactcatttcacctttttctcagaga cacactattctaccacctggctcaatgaggatattagacgttagggttactgacgctgga acatatacttgtgtagctacaaacatagcaggaaatgttactcaaatagtaacactcaat gtctatgccccacccaaaatccagcgtggccctcaaatgataagaatacaagttaaacaa agctttgaaattgcctgcataagtcaagggatcccaccaccaagaacagcctggtttaaa gatggaagaatgttgacgctggatgaaaagcttcagcactttacaatcagagttgctagt gctgaactttcagatgctggagtatacacttgcattgccagtaacatggttggtcaggac agtgcaaatgtgacaatagaggttcaagcaccacctacgttgtctgatttggagcctcct tatgacaaaacacaccaggaaaggctttcaagtcaacaggttgcatttccctgccctgca aaaggtaatcctaaaccggttattaaatggttacgtaacaacaaagagttatctgggaca gaacctggtatcaagattgcagaagatgggactctgctcatcatcagttctttgacatcg tatgacaatggagaatataagtgtgtggcctctaatcaggcaggattgacggaaaggaaa tataatttgaaagttcatgatcctccagctattaaagacaaggaaaaactgacaaatgta tccgttttgttgagtcatgacacaaacttattttgtgatgctacaggaagtccgccacct tttatcacatggtataatggaagtactcaggtcattgaaagtgataatatcaagatttta gaaaaaggaagaattctgaagattatgaaaacaaccttgtcacattctggatcttttagt tgcactgccagcaacattgcagggagtgatgaaaagcacttctttgtagatgtgctagaa ccacctgaaattgctggtcgtggaacagtcgatgatatttctgtaattattggaagagcg gctaagttaaaatgtgaggtaaaaggaaagccctatcctgctattcagtggttcaaagat aatagattagttggaggaggagacacaaatgttaatattttagaaaatggacaaactttg tacataaagaactcacgtttaactgacagtggacaatataaatgcgtagcaaccaattca gctggtttgcaaactaaagaaagtaaattagttgttaatgttccacccagcattaagaat gaaaacactacgacagagttatcttttaatgtggacagcagagtcagccttgaatgcgat gtttggggaattcctcaccctgcaataacatggtatacagatggtaaaagaattcaggcg agcacacatatcagtttcattgaaaatggcaaatatcttcatatttcagaggtgaaggtt acacattcaggcaaatacaagtgttatgcaaccaattctgcaggacatgctgagagagag tatctgcttgatgtttatgctccggcttccattcataaagacttaagcaagcctcaaacc acaaaggtcatagttggtaaaacacttgtactggaatgtgaagccacaggacatccatta cccttaatcacttggctaaaagaaggagtgcctatacagataagtgataacatacgactt ctgtataatggaaaaaagctggagataaagtcaacagtggagtctgaccaaggacagtat atctgtgtggccacaaatctagcaggaaaatctgaaatgatatacaatgttcacatttta gtaccgccaactatagaggatattgatgatccaggagagtacactgtcattgccagcaat cctgtggaactggaatgctatatcaaaggaatcccccttccagctgtaatgtggctaaaa aatggaattcctcttgagccaagcaatgatttgcatattcaagacaaaggacaaaagctc ataatttcaagctcaggctcatccgatagtggagtttatgagtgtgttgtgaaaaatgag gctgggacaagtagaaaaatatttaacgtcaatgtgcatgtcctgccttccattaaacct gagccatcaccattgtctgttgtaatgcgcaaacccatcattttgcagtgtattgctact ggaattcctagcccacaaatcacatggttaaaggatggactaccatttaatatcattaaa gaaaatatctcagtggaatcgtttggtcgtattctacatttcaaaagcacaatgacagat gatgcggggaagtattcctgtgtggcaagcaatgcagctggagaggctgagcaaagcata tggctaaatgtctatgaaccacccaaaatagagaattcggacgaagtccaccatgaaacc atacttggcaatcaatctgtaagactggaatgcaaagcatcaggcaaccccgatcctgtt gtaacttggttaaaagataaccatccccttacaattgttgataatattctcctgtcaaat caaggacaagtcctccagataacaaatgcaaagatacacaatgccggtgtatataaatgt gttgcaagcagcctcgtagggacagctgaaatgacttatgtcttacaagttcatgttcta ccttccatttttggtaacaatgatcctgtatctgtgatagtcaacaaacccgtcagatta gaatgcgaagccacagggttcccagctcccagtttaacatggctaaaagatggcatccca gtttccagtatcagtggcggaattcagattctttcaggtggaagagttctaatgctagcc aatacacggattggagatgcagggaaatatacatgtgtggcagttaatgctgcaggagaa catcaaaaggattttgatttatctgtgtatgtgccaccaaacataatgggagaacagcaa aatataacaatcctaatgggccaaaaactttcactgaaatgtgaaagcaatgcaatacca cctcctgtgctgatgtggtttaaagactggagaccattggtaaacagaccaggacttggc atttctgagagtggacagtttttggagattgaaaatgctcaagtgaaggatactggacgg tattcttgtgaggctgtaaatattgctggaagaacacaaaggaattttaatgtgaatatt ttagttcctccaacgataaaagattcagaggaagaatcagatgttacagtaattgaagga acactgataagtcttgtgtgtgattccagcggtattccacccccagcactgacttggaaa aagaatgatactccagtaacaccggacagcaaaggtcggattcgttttctgtcaggaggg agacatcttcatattgcagttgctatggaatctgatgcatcatcatatacatgcacggct tccaacacagcagggaatgcagcaaaaaagtataatgtgaaggtttatgtacatcccagt atatcgggaggtggacctgcacccttggatgtggtagtaattgaagaaaataatgtgact atggaatgtgaccctagtggaagtccacaacccatgctgacttggcttagagaagggatt cctttaaataatggggatggacttaaaatcctcagaaatggaagacagctacatttagaa aaagcacaggcttcagattctggactgtatctatgtgtagcagtgaatgtggctgggcaa gcggataaaaaatatgatttaaaggtgttcgtccctccaagaattttgggatcatttgaa gagcatgaaaatgtaagtgtagtggagagaaatccagtgactttaacatgtgaagtatcg ggtatcccaccacccaaaataacatggttcaaagatggtcagcccattcacccaaacaat acacctcaagtcatgtcaggtggtatgaccttacggtttgtgcacacagccctctctgat gctggaagatacaagtgtgttgtgtccaatgctgctggagtgaaaaataaagagttccac cttaatgtattagtgcccccaagacttacaggaaatgttttggaagacataaaagtgaaa gaaaaaagtgacgttgtcctttcctgtgaagcaacaggcaatcctgtaccacaaataacc tggctaaaagatggacagccattacaagaggacacccatcatcgtattaaagatggcggc caacactttcaaattattagtgccatggaaactgacacaggaagatacacttgcattgtt tccaatttagcaggggataaaagcagaagatttagtcttgctgtgatggtatctccaata atctctggtgctaaaccaaaagaatctcctgaggatatcagtgtaattcaggacagctct gtattattggcctgtgaagttcattccattcctacatctaccatagtctggtataaagat ggacaacaaatacattccaaggataacatcagaattctcccaggagggcatactctacag atcttgaaggcccatgaagacaactttggaaagtacagctgcattgctgctaatgaagca ggagtggctgaacatcattataatttgaaagtttacactcctcctcgtattacaaaggat aatcttgcaggaaccggatatttatcaaagcagataaaagctaaagtgggcacaaacatt tcattagaatgtaatgtgcaggctttcccagtagccacagttaggtggtacaaagatggg cagccacttgatcctagaagtcttatagttaatggtaacaagcttaacatagataaagca gacttgtctgatacaggacgttatacatgtgtggcctccaatgttgctggagaagatgaa ctcgattttgatgtcaatatacaagttcctccaaacttcccgaagttgtctagcctcctg ctgaatactgacagcagcatcgtggaaagaataggagagagaaaagatgttattgtcaac aatccatttactctgtattgtgaaacaaatgccattccaccaccaactatcacatggtat aaagatggcaaggttctaacttccagtgacaagacatttctatcaccaggtggacacagt ctacagattgcaagagcacgcatggaggatgctgggacatacagttgtgttgctgtaaat gaggcaggagaggattccctgcagtataatgtgcgaatactattgccaccaacctttgag gggggaagtgaaaatttgtcagaggatgtatcatttctggcaaatcagacagtgttgctg gactgtgtgggggaaagcattcctgctccaactgtgagctggcagaaggatggacaggcc attaaagatggaaagcactatcagattttatccgatggaagatacttgcagatctcaaat gctgagttatcagatactggtcgttacatctgcattgtggagaatgtagcaggaagtgca cagaaattgttcaagctgaacatctatgttccccccaaagtcacaggggatgcctttgaa aatgttactgccatagaaaatgatttcatctccctatcatgtgatgtaactggatttcca ccacctgcaataaattggataaaggatggcaatgtcctcagttctagcaagcatctatta attgtcccaggtggtcgagttttgcagattcctcagatgaaactaacagacgctggtgat tatgtatgtgtggccatcaatcaagccggtgaaagcaagaaaacattctaccttagtatt tttgttcctcccaccatcataggtagtggcagagattctagtactgaggtgaacattaac attgctacatctgcgtcacttgaatgctttacaaatgctgtcccacctgctgtcattaac tggtataaaaatggtcaaatgctcttggaatccacaaattacattattctggatgaagga caaataatgaagataaagaatgcccaggtatctgatactggtgaatatgaatgtgtagca accaatgttgctgggcaagacaagaagacatttttagtgaatgtttatgtaccacccagt atacaaggtccccaagtggaatataataatggaatcattgaaaactctgttaccttgcac tgcaatgcttatggtataccccctccaacaattacctggcttaaggatggaaatcctata aattattcagattccttggaaatactctttctttctggaggaagtattatgaagataacc agggctcagctgacaaacagtgggaattacacatgtcttgcatcaaacatagaaggcagc actcacaaaaccttcattttggctgttcaagttccccctagcattactgggtctggaaca tccaatgaagtcaatgctctgccagatgatgatgtacagcttatgtgtaagaccagagga gtcccaacacctgtggtccattggtcaaaggatggccaacccattaacactgatgatcgc cttaacatcaggaaaattgataatggggagatactatccattccaaaagtccaaagagct gatatgggaaaatacacatgtgtagctatcaatttagcaggcgaagatgatcgcattttt cacctaaatgtgtatgttcctcccaagattgctgataatgaagaaacagtgtcaatagca gcagctttggagacatcagtaaacattgaatgttttgtaactggtgatccaacaccacaa atcaactggctaaaaaatggccttcctcttcctgtatcctcacaaatacgacctctttct tctggaaaaatcttaaggatttcaagattacagaaatctgatgaaggattctacacatgc gtggcttcaaacagggctggtgttgacaaaaaaaaatacaatttaaaggtgtacattgcg ccaactatggacggttcagatataaccgaggagctcaccaccatcaagggaaatccaact acaatgaggtgcattgctgatggataccctgaaccccatatctcatggttaagaaatgga aaatatattgaccttgtgcccaataaagggacaacattccacatcctgaataccgaaatt actgatattggtagatatacatgtactgcaactaacgaggcaggcagtatcagcaaacat ttcatactaaatgttctggagccaccacatataaatgggtcaaggtacattgatgaatta tcagtaactatcaataaccaagtggagctggtttgctatacaacaggatttccctctcca ctaattaattggcttaaagacggtcagcttctttctcagactgagaatgtgcactttatt aaaggggggcagatacttcaaataaccagtgcacaggaagaaaatgtagggttgtatacc tgcctggcttcaaacaatgctggaaacaccaagaaagaattttctgtaaaagttcacatg ccccctaacattgctggcatcaatggcatccataatataacttcacttaaggataaacaa gttactctggaatgtaaatcagatgctgtccctccaccagaaatcacgtggctaaaggat aataagccattgttgcccagtgttagaatacacattgaatctgatggacgatttgtacat atcaatagtgcagaggtggaagatgctggacattatatctgtattgctagaaacattgct ggaaaaactaccagggagtttatccttaatatatatgttcctccaacaataaaagatgga ccaaacctagttacaagttttgtcaacaatcctgccaatttggagtgcaaggctgctgga gtcccactgccccgcatatcatggagaaaaaatggagctatcctccatgagaacaatgag aggtatactgttatggaatctggcacactttattttccatcagccaatgttacagactct ggcctgtacacctgccttgcagctaatgcagctggatcgaaccagaagcagaccaaactt ttggtttatgatcctccactgataaactctggctcaacaaatattaccacaatagtgaat aatgaaataacattaaactgtgaagtaacaggtacccctaaaccaacagtggaatggaag aaaaatggactgttaataaacacaaatatgaattacaacatttacagatttctttcttca ggatctctcataatcatttcgacagctgtagaagacacagggatgtatgtgtgttttgct tcaaatgatgcaggtcatgatgaaattgcaatttatctttcagtacttgtgccaccttcc atcgctgatgaagtaacaaatatatttattaataaattgtcatcatccataattccttgt actacgtatggtgttccacagcctgtagttcattggttgaaggatggaattcgccttcca gctgttggagaaagttacaagatattgagttctggaagtattgaaataccacgtacagac ttaacccatactggaagatactcttgcaaggcaataaatgaggttggctcggctgagatt catataaatctctatgttcaagaggttcctgttatatacagtcaaggtgattactttgaa gccacagtaaacaattccatcacactttcatgtgaagcacttgggacaccttcacccact atcacgtggcaaaaggaaggtgttggcatcaaaacagggggtcattttactatgtttatt aatggcaaccttaacattgcatatgttacacaagaagatggcggtacttatacttgcatt gcccaaaatccagctggaacagcattggggaagataaaacttaaagttcttgagccacca ttaataaaaccacataagaaagaatatacagttgtagtggatgagcctgtcacaatgatc tgtgaggcctttggcaacccgatgccagagattgcttggcataaaaatggagcacctctt tccaagtcagctgtacagagaataatcggcactggagctcttcaaataggatatgcacag cctgatgatgcaggcctgtacacatgtacagcagaaaatgcagtgggatccatgagctcc agtatgaatctatcggttttagttcctcctcaaattcaaaaaaaaattaatgaattattt gtgatacaaagttttccagttactattccttgtaatacatatggaattcctactccatca atagcctggacaaagaacaatgtttcaatagcagataacagtgaaaaatatgctgtgact aaatctggggatttaattttgcgtcaaacagagcatcatgatatgggtaattacacctgt actgccagtaatattgttgggaaggattctcacacaattagtatcactatccagtatggt ccatcctttacagaactgccttcagatgtatcattgaataaagaagaaaaactgagatta acatgtaaagcgacaggaaaccctcgccctcagataacatggacatttaagcataaatca acacctgtgcagattgggcaatctaaatatctgaatgattttgtaattgagagggtttca aaagaggattctggcacctatacttgcatagcagaaaatattgttgcatcaattaatact acagtgaaagtttttgtaaaagagcctcctgttcttgttgggttccaccacaccaatctg actgcagcactaggaggcagcattatcctaaattgtatagtacaagggaatcctatacct aaaattcagtggaataagaaagaaaatgatatcccttttaataggcgatttaaacagttc aataatggctctcttgcaatttacaacacaacaaatgaagatattggtgattttatatgt atagctacaaatgatgctggaacaatggggcacacggtaacactgtccctgcaaaaacct cccattataaagagtcctccagttgacatgacagttaatgctggtacatctgtggttttg aattgtcaagcagaaggagaaccagtgcctgacattttctggtctcgtcttactcgtcct atttctggggatagccgtttctcaatattgtcaaataaatctctgcatatagttgctgtt cgtaaagaagatacatcagtgtatgaatgcagggctacaaatgtcatgggatcagctgtg gctaagtcttctttcattgttcaagttcatggtggattttccgaatggctgccatggcaa tcctgcagtgtgacttgtggtcaaggaatacaaaaaaggatgaggctgtgtgacaatcca gccccagcaaatggtggattgtattgccagggagaagaatccgagacccgtctctgtcaa aataaaccttgcccagctgatgcaagttggttagactggagcccatgggaagagtgctct aaaacttgtggaagtggcaaacaaacaagaacaagaatttgcaatattcctccagcccaa gaaggaggaaagacatgtgatggaaaagctattgacaccaaagtttgtaacatcaaatcc tgcccagttgatggagaatggagttcctggcaagtgtggggtccatgcagtaagacatgt gggaagggaactcaaatacgtgcaaggctctgtaataatccacctccatcctttggtgga acattttgtgaaggacaagacacgcaatcacaaatatgtaacatacgccattgtccagtg gatgggaaatggtcaccctggggaagttggacaccttgcagtgtttcctgcaatggaggc cttcgacaaagaactcgtgaatgttccagtccacaaccacaatacggaggccacaagtgt aaagggaaagcatttgagaatgagttttgcaacggagactcatgtcctattcatggaaac tggggaccatggagcgcatgggaaacatgtagtcgtacatgcaatggaggccagaggagg aggcatcgcacctgtgacagccctactccttcacataatggaagaggatgtgctggaaag gatacagaaatacacaagtgtaacactgaaatatgtcctgctgatagtaactggggtcca tgggaagcatggagtaaatgttctgtatcatgtggaggtggccaacagattcgaacgcgt atttgtaaacatcctgtcaggtccaacaatggccgaacatgcccaggggattccacgcag cttttgagatgtaatgttcaaggttgccagggaggagttcagtctgtaagaggaacgtta tcaggaaccattaatgatgttgaccttcacattgcacagctaaatggttcagtttccaac aattcggaatcacatgcaagtacaattaaagcaacatttacaaacatccctaaaagtctt ggttcttctatgaggaatcttgcatctttattggatcccatatattggacagtagcaaaa gaaagaggagaagcagtaaatggatttactctgacgggtggtgaatttataagagaaact caagtggaatttgcaacaggagaaatcatgagaatcactcacaattctcgcggtcttgat gctgatggcttcctcttggtggacacagtggtgaaaggatatattccacagttacctatt tctactaacatcaaattaaagggttacacagaggattatgtccagactggtcttggacaa ctttatgcttattcaacaagaatgttctatctcgacgaagtgagtgtgccatacacctgg aatcacactgtcagctatgaccccagccatggaaaaatgcctgtcatgttggagactttg catgtgtcttccataggagcggattacaatccattagaagaaactctaagctttcaaatg catgctttcatctccaaaggtgacattgatgaccagtgtcctcctggatttagttatgac atctctggactttattgtgcagatgatgatgaatgtgccataaacagtccatgcacacaa tcttgccataatattatggggagttactactgttcatgccctaaaggcttcatgacttca ccagatggaaggacgtgtcttgatattgatgaatgtacactggaagagtctgtgtgtcgc aaaaatcaagagtgtaaaaattccattggttcttatatttgtgtactaaagtgtggaact ggatttacagctgctcctaatggcctggaatgccaagacattaatgaatgcaaggagtca aatccttgtcatcaacgctgcttcaatacaattggaagctatcgctgtggatgtgatcca ggttatcatttgaaaggcagaagttgttttgatttaaatgaatgtcatcagaatgtatgt cgacctgatcaactttgcagaaacacacgtggaagttataagtgcattgacatttgtccc attggatttacaaaggctgaaaatggatcatgcgtagatattgatgagtgcagggattct tcacatcgttgtaaaagcaatcaaatatgtgaaaacacacagggaagatatctgtgtgtt tgtcctcgtggattcaagtctgaaggccctggaaagccatgcaaagacgtaaatgaatgt gaaaagcaagatgtgtgtcaacatgaatgcagaaatgttcttggaagttatcagtgctta tgtcctactggttaccagctcatggccaatgaaaagacatgccaagatatagatgaatgc cttgttcataacattcattgtggggtaaatcagatgtgtttcaacatgagaggaagccac caatgcatagataccccttgtcctcctaattatgtgcgcgactcttctgggtattgtttg aaaaattgcgcaccgaatgatctggagtgtgcgcttagcccatatgccttgcaatacaag ctggtttcacttccatttggtatcgctgctaaccaggacttaattcgcttggttgcctat acacaagatggcatattacatccaagaacaacttttctgatcaccgatgaagattctaca gtgccattttctataagagaagaaaacatgaagggcgtagtatttaccaacagaccactt aaagaaccagaaacctacagaatgaaagtgagggccttatcatacagcacagatcgcacc attgaatatcagactacttttattgtttatatttctgtgtctccctatccttattaa

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