Raoultella terrigena: NCTC13098_06326
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Entry
NCTC13098_06326 CDS
T06046
Symbol
thrA
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
rtg
Raoultella terrigena
Pathway
rtg00260
Glycine, serine and threonine metabolism
rtg00261
Monobactam biosynthesis
rtg00270
Cysteine and methionine metabolism
rtg00300
Lysine biosynthesis
rtg01100
Metabolic pathways
rtg01110
Biosynthesis of secondary metabolites
rtg01120
Microbial metabolism in diverse environments
rtg01230
Biosynthesis of amino acids
Module
rtg_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
rtg_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
rtg00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC13098_06326 (thrA)
00270 Cysteine and methionine metabolism
NCTC13098_06326 (thrA)
00300 Lysine biosynthesis
NCTC13098_06326 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC13098_06326 (thrA)
Enzymes [BR:
rtg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC13098_06326 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC13098_06326 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
VDR29901
UniProt:
A0A3P8KRA4
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All DBs
Position
1:complement(5287177..5289639)
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LTNIADAERIFAELLQGLADAQPGFALAQLKTFVEQEFSQIKHVLHGISLLGQCPDSVNA
ALICRGEKLSIAIMAGLLEARGHKVSVINPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASLD
EDGLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKRVMEEEFYLELKEGQLEPLAIMDRLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIKRQQGWLKNKHIDLRVCGVANSQALLTNVHGLNLENWRAELAEAKESLNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELLHFSGILSGSLSFIFGKLDEGMTLSAATTLA
RDMGYTEPDPRDDLSGVDVARKLLILARETGRELELSDIIVESALPEAFDASGDVESFMA
RLPALDNEFASRVAKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatattctggagagcaatgccaggcaggggcaggtagcgaccgtactgtctgccccg
gcgaaaattaccaaccatctggtcgcgatgattgaaaaaaccatcggcggccaggatgcg
ctcaccaatatcgctgatgctgaacgcatttttgctgaactgctgcagggtctcgccgat
gctcagccgggctttgcgctggcgcagctgaaaaccttcgtcgagcaggagttttcccag
ataaagcacgtgctgcacggcatcagcctgcttggccagtgcccggatagcgttaacgct
gcgctgatttgccgcggagagaagctctccatcgcgatcatggccggccttcttgaagcg
cgtggccataaggtcagcgtgattaaccccgttgaaaaactgctggccgtgggccactac
ctcgaatccaccgtcgatattgccgaatcaacccgccgcattgccgccagccagatccca
gcggaccatatggtgctgatggccggatttaccgccggcaacgaaaagggcgagctggtg
gttctgggccgtaacggctccgactattctgccgccgtactcgccgcctgcctgcgcgcc
gactgttgcgaaatctggaccgacgttgacggcgtttacacctgcgatccgcgtcaggta
ccggacgcccgcctgctgaagtcgatgtcctatcaggaagcgatggagctctcctacttc
ggcgctaaggtactgcacccgcgcaccatcgcacctatcgctcagttccagatcccctgc
ctgatcaaaaataccggcaatccgcaggcgccgggtacgcttatcggcgccagccttgat
gaagatggcctgccggttaaggggatctccaacctcaataatatggcgatgttcaacgtc
tccggtccggggatgaagggaatggtcggcatggccgcccgcgttttcgccactatgtcc
cgcgccggcatttcggtggtcctgatcacccagtcctcttctgagtacagcatcagcttc
tgcgtgccacaaagcgactgcgcccgggcaaaacgggtgatggaagaggagttctatctg
gagctgaaagaggggcagctggagccgctcgccattatggatcgcctggctatcatttcc
gtcgtcggcgacggtatgcgcaccctgcgcggtatttcggccaagttcttcgcggcgctg
gcgcgcgccaatatcaatatcgtggcaattgcccagggctcttccgaacgctctatctcc
gtagtggtcagcaatgatgacgccactaccggggtccgcgtcacccaccagatgctgttc
aataccgaccaggtcattgaggtgttcgttatcggcgtcggcggcgttggcggcgcgctg
attgagcaaatcaagcgtcagcagggctggctgaagaacaagcatatcgacctgcgcgtg
tgcggcgtcgccaattcccaggctctgctgaccaacgttcacggtctgaatctggagaac
tggcgcgctgagctggcggaagcgaaagagtcgcttaacctcggccgcctgatccgcttg
gtgaaagagtatcacctactcaacccggtgatcgttgactgtacctcgagccaggcggtc
gccgatcagtacgccgatttcctgcgcgaaggtttccacgtggtgacgccgaacaaaaag
gccaacacctcgtcgctggattactatcatcagctgcgtcacgcggcgagcagctcccga
cgcaaattcctctacgacactaacgtcggtgccggtctgccggttatcgagaacctgcag
aacctgctcaacgccggtgacgaactgctgcacttctccggtattctctccggctcgctg
tcgtttatcttcggtaagctggacgaggggatgacgctctccgcggcgacgacgctggcg
cgggatatgggctataccgaaccggatccgcgcgacgatctttccggcgtcgacgttgcc
cgcaagctgctgatcctggcccgtgagaccggccgcgagctggagctgtcggacattatc
gttgagtcggctctgcctgaagcgtttgatgccagcggcgacgtcgagagctttatggcg
cgtctgccagcgctggataacgaatttgcttcgcgggtggcgaaagcgcgcgatgaaggt
aaagtcttgcgttacgtcggtaacatcgaagaggatggaacctgccgcgtgaaaattgcc
gcggttgacgggaacgatccgctgtttaaagtcaaaaacggtgagaacgcgctggccttt
tacagccactattatcagccgctgccgctggtgctgcgcggctatggcgcgggtaacgat
gtgaccgcggccggcgtattcgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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